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The map label for this gene is ctaC [H]

Identifier: 71907103

GI number: 71907103

Start: 1593961

End: 1595166

Strand: Reverse

Name: ctaC [H]

Synonym: Daro_1471

Alternate gene names: 71907103

Gene position: 1595166-1593961 (Counterclockwise)

Preceding gene: 71907106

Following gene: 71907102

Centisome position: 35.44

GC content: 63.35

Gene sequence:

>1206_bases
ATGGTGATCGTACCGCAAGATTCTTCGGCCAGCCGCCGTCGCCGGCGGCTTTCCCTGCTCCGACGAGCAGCCCGCCTTGC
CCCCGCCCTGCTCCCTGCTTCCGCCAGCGCAGGCTACAGCTTCAACTTCCCCGAGCCGGTCACGCCCATCGCCCGGGAAA
CGCTGCACATCCACAACGAGTTCATGCTGATCATCACCACGCTGTTCGTGGTGGTCTTCGCCATCATGATCTACTCGATG
ATCCGGCACCGGAAAAGCAGCGGCCACCAGCCGTCGAAATTCTCCGGCCCGACCGGCGCCCTGCAATGGTTTTGGGCGCT
CATTCCGTTCGCCATCCTGCTGTTCATCGACTTCGTGCTGATGGGTATCCCGGCGGTGCAGGCCATCATCAACATGGAAG
ACACCAAGACCAAGGCCGATCTCGTGCTCAAGGTCACCGGCATGCAGTGGAAATGGCAGTACGAATACCCCGAGGCCGGG
GTCAAGTTCATCAGCACCCTGGCCACGCCGCGCGACCAGATCACCAACGCCGAGGCCAAGGGCGAGCACTATCTGCTCGA
AGTCGACAAGCCGGTGGTGTTGCCGGTTGGCAAGAAGGTGCGCGTGCTGCTCACTTCGATCGATGTCATCCACACCTGGT
GGGTGCCGCAGTTCGGCGTCAAGCGCGATGCCATTCCCGGCTTCCTGCGCGAAACCTGGGTACTGATCGAGAAGCCCGGA
ATCTACCGCGGCCAGTGCGCCGAACTGTGCGGCAAGGATCATGGCTTCATGCCGGTGGTCGTCCATGCCGTGCCGGAACC
GGAATACCTCGCCTGGCTGGAAGCGCAAAAGGCCGAAGCCAAGGCAACCGCCGGCGGGGCCGACCGGACATGGAGCCGCG
ACGAGCTGATGGCCCAGGGCAAGGCCGTCTATGAAAAAGTCTGCGCCGCCTGCCACCAGCCCGATGGCAAGGGGCTGCCG
CCGGCCTTCCCGGCGCTGGCCGGCAGCAAGATCGTCAATGGACCGCTGCTCGACATGAACGGCAAGGTGATCACGGACAG
CCACGTCGACCGGGTAATGCACGGCAAGGCGGGCACCGCCATGCAGGCATTCAGCACCAGCCTGTCCGATGTCGAACTGG
CCGGCATCATCACTTACGAACGCAACAGTTTCGGCAACCAGATGGGCGACATGATCCAGCCCGCCCAGATCAAGGCCCTG
CGCTAG

Upstream 100 bases:

>100_bases
GAGAAATTGGCGGCGATGCATGATGTTAAATATTGTTGAACTAATTACGAAAGTTTGATTCTCACCGGACGAATCGGTTC
TCACAAGGGGAGGGAACGGG

Downstream 100 bases:

>100_bases
GAGAACCGAGATGAGCCTCGCCACCACCCATCCTGCCGCCCACCCCGAGCACCACGAGCCGACCGGCCTGCTGCGCTGGC
TGACGACGACGAATCACAAG

Product: cytochrome c oxidase, subunit II:cytochrome c, class I:cytochrome C oxidase subunit II, transmembrane region

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MVIVPQDSSASRRRRRLSLLRRAARLAPALLPASASAGYSFNFPEPVTPIARETLHIHNEFMLIITTLFVVVFAIMIYSM
IRHRKSSGHQPSKFSGPTGALQWFWALIPFAILLFIDFVLMGIPAVQAIINMEDTKTKADLVLKVTGMQWKWQYEYPEAG
VKFISTLATPRDQITNAEAKGEHYLLEVDKPVVLPVGKKVRVLLTSIDVIHTWWVPQFGVKRDAIPGFLRETWVLIEKPG
IYRGQCAELCGKDHGFMPVVVHAVPEPEYLAWLEAQKAEAKATAGGADRTWSRDELMAQGKAVYEKVCAACHQPDGKGLP
PAFPALAGSKIVNGPLLDMNGKVITDSHVDRVMHGKAGTAMQAFSTSLSDVELAGIITYERNSFGNQMGDMIQPAQIKAL
R

Sequences:

>Translated_401_residues
MVIVPQDSSASRRRRRLSLLRRAARLAPALLPASASAGYSFNFPEPVTPIARETLHIHNEFMLIITTLFVVVFAIMIYSM
IRHRKSSGHQPSKFSGPTGALQWFWALIPFAILLFIDFVLMGIPAVQAIINMEDTKTKADLVLKVTGMQWKWQYEYPEAG
VKFISTLATPRDQITNAEAKGEHYLLEVDKPVVLPVGKKVRVLLTSIDVIHTWWVPQFGVKRDAIPGFLRETWVLIEKPG
IYRGQCAELCGKDHGFMPVVVHAVPEPEYLAWLEAQKAEAKATAGGADRTWSRDELMAQGKAVYEKVCAACHQPDGKGLP
PAFPALAGSKIVNGPLLDMNGKVITDSHVDRVMHGKAGTAMQAFSTSLSDVELAGIITYERNSFGNQMGDMIQPAQIKAL
R
>Mature_401_residues
MVIVPQDSSASRRRRRLSLLRRAARLAPALLPASASAGYSFNFPEPVTPIARETLHIHNEFMLIITTLFVVVFAIMIYSM
IRHRKSSGHQPSKFSGPTGALQWFWALIPFAILLFIDFVLMGIPAVQAIINMEDTKTKADLVLKVTGMQWKWQYEYPEAG
VKFISTLATPRDQITNAEAKGEHYLLEVDKPVVLPVGKKVRVLLTSIDVIHTWWVPQFGVKRDAIPGFLRETWVLIEKPG
IYRGQCAELCGKDHGFMPVVVHAVPEPEYLAWLEAQKAEAKATAGGADRTWSRDELMAQGKAVYEKVCAACHQPDGKGLP
PAFPALAGSKIVNGPLLDMNGKVITDSHVDRVMHGKAGTAMQAFSTSLSDVELAGIITYERNSFGNQMGDMIQPAQIKAL
R

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=219, Percent_Identity=32.8767123287671, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6226540, Length=244, Percent_Identity=29.5081967213115, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 44370; Mature: 44370

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIVPQDSSASRRRRRLSLLRRAARLAPALLPASASAGYSFNFPEPVTPIARETLHIHNE
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FMLIITTLFVVVFAIMIYSMIRHRKSSGHQPSKFSGPTGALQWFWALIPFAILLFIDFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MGIPAVQAIINMEDTKTKADLVLKVTGMQWKWQYEYPEAGVKFISTLATPRDQITNAEAK
HHHHHHHHHHCCCCCCCCEEEEEEEECCEEEEEECCCHHHHHHHHHHCCCHHHHCCCCCC
GEHYLLEVDKPVVLPVGKKVRVLLTSIDVIHTWWVPQFGVKRDAIPGFLRETWVLIEKPG
CCEEEEEECCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEECCC
IYRGQCAELCGKDHGFMPVVVHAVPEPEYLAWLEAQKAEAKATAGGADRTWSRDELMAQG
CCCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
KAVYEKVCAACHQPDGKGLPPAFPALAGSKIVNGPLLDMNGKVITDSHVDRVMHGKAGTA
HHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCEECCCCCEECHHHHHHHHCCCCCHH
MQAFSTSLSDVELAGIITYERNSFGNQMGDMIQPAQIKALR
HHHHHCCCCCEEEEEEEEECCCHHHHHHHHCCCCCHHEECC
>Mature Secondary Structure
MVIVPQDSSASRRRRRLSLLRRAARLAPALLPASASAGYSFNFPEPVTPIARETLHIHNE
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FMLIITTLFVVVFAIMIYSMIRHRKSSGHQPSKFSGPTGALQWFWALIPFAILLFIDFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MGIPAVQAIINMEDTKTKADLVLKVTGMQWKWQYEYPEAGVKFISTLATPRDQITNAEAK
HHHHHHHHHHCCCCCCCCEEEEEEEECCEEEEEECCCHHHHHHHHHHCCCHHHHCCCCCC
GEHYLLEVDKPVVLPVGKKVRVLLTSIDVIHTWWVPQFGVKRDAIPGFLRETWVLIEKPG
CCEEEEEECCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEECCC
IYRGQCAELCGKDHGFMPVVVHAVPEPEYLAWLEAQKAEAKATAGGADRTWSRDELMAQG
CCCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
KAVYEKVCAACHQPDGKGLPPAFPALAGSKIVNGPLLDMNGKVITDSHVDRVMHGKAGTA
HHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCEECCCCCEECHHHHHHHHCCCCCHH
MQAFSTSLSDVELAGIITYERNSFGNQMGDMIQPAQIKALR
HHHHHCCCCCEEEEEEEEECCCHHHHHHHHCCCCCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2820725; 7651515; 9380672 [H]