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The map label for this gene is tas [H]

Identifier: 71906759

GI number: 71906759

Start: 1222919

End: 1223965

Strand: Reverse

Name: tas [H]

Synonym: Daro_1120

Alternate gene names: 71906759

Gene position: 1223965-1222919 (Counterclockwise)

Preceding gene: 71906760

Following gene: 71906758

Centisome position: 27.19

GC content: 59.69

Gene sequence:

>1047_bases
ATGAATCCTTTCCAGAAAAATCCGCTAGGGCGCAACCACTTCGAAGTTCCCGAAGTCTGTCTTGGCACGATGACCTTCGG
TGAGCAGACCAGCGAGAGTGACGCGCACGCCCAGCTCGACTTTGCGCTGGCCAATGGCATCAATTTCATCGACACCGCAG
AGATGTATGCTGTCCCGCCACGCGCGGAAACCTGTGGCGCCTCGGAAACCATTGTCGGCCACTGGTTGAAGCGCCAGGCC
CGCGACAAGGTCTTGATCGCGACCAAGGTCGCCGGCCCAAGCCGCAACCTGAACTGGATCCGCAACGGTCCGCCTGCCCT
GGACAGAACAAATATCCGAGCAGCCATCGACGGTTCGTTGCAACGCCTGCAAACGGATTACGTCGACCTCTACCAACTTC
ACTGGCCCGAGCGCAACCAGCCGATGTTCGGACAATGGCAATTCGATCCCGACAAGGAACGCGACGGCACTCCCATCCGT
GAGCAGCTTGAAGCACTCGGCGAACTCGTTCGGGAGGGCAAGATCCGCCATATCGGCGTCTCCAACGAACACCCGTGGGG
CATCATGCAATTCACCCGGCTGGCCGATGAATTGGGCCTGCCGCACATCGTGTCGACGCAAAATTCCTACAGCCTGCTGA
ACCGCACTTTTGAAACGGGACTGGCTGAAGTCTGTCACCGCGAACGGGTCGGCCTGCTGGCCTACTCCCCCCTCGCTTTC
GGGCACCTGACCGGCAAATATTTGAACCAACCGGATGCGCCGGGCCGCCTGACCCAATGGCCGAGCTTTGGACAACGCTA
CACCAAACCCAACGTCATTCCCGCCGTTCAGGCTTACGCCGAGCTGGCCAGGAAACATGACCTGACACCAACTCAGCTGG
CACTCGGTTTCGCCCGGTCGCGCTGGTTCGTCGCCAGTACCATCATCGGCGCCTCGTCGCTTGAACAACTCAAGGAAACG
CTACCGGCCACGCAGACGCCGATGTCGCAAGAAATACTGGCCGAGATCGACGCCATCCATTTGCGCTACACCAATCCTGC
GCCATGA

Upstream 100 bases:

>100_bases
CTCGCTATCGTCCCGGCCGGCTACGACTCAATACTTGAGCGCCACATACTGATATATGGCGTTCTTGGCGGACAACCATG
ATGCATATCGGAGACCTCTC

Downstream 100 bases:

>100_bases
CCGAATCGCTGTTTCCACGCCTATCAAATGCCCTCGCGGCGACCGATATCGCCGAGAAGATCGAGTTGACGGCGAAAATC
GCTGCAGACTGGCGGGCCGG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MNPFQKNPLGRNHFEVPEVCLGTMTFGEQTSESDAHAQLDFALANGINFIDTAEMYAVPPRAETCGASETIVGHWLKRQA
RDKVLIATKVAGPSRNLNWIRNGPPALDRTNIRAAIDGSLQRLQTDYVDLYQLHWPERNQPMFGQWQFDPDKERDGTPIR
EQLEALGELVREGKIRHIGVSNEHPWGIMQFTRLADELGLPHIVSTQNSYSLLNRTFETGLAEVCHRERVGLLAYSPLAF
GHLTGKYLNQPDAPGRLTQWPSFGQRYTKPNVIPAVQAYAELARKHDLTPTQLALGFARSRWFVASTIIGASSLEQLKET
LPATQTPMSQEILAEIDAIHLRYTNPAP

Sequences:

>Translated_348_residues
MNPFQKNPLGRNHFEVPEVCLGTMTFGEQTSESDAHAQLDFALANGINFIDTAEMYAVPPRAETCGASETIVGHWLKRQA
RDKVLIATKVAGPSRNLNWIRNGPPALDRTNIRAAIDGSLQRLQTDYVDLYQLHWPERNQPMFGQWQFDPDKERDGTPIR
EQLEALGELVREGKIRHIGVSNEHPWGIMQFTRLADELGLPHIVSTQNSYSLLNRTFETGLAEVCHRERVGLLAYSPLAF
GHLTGKYLNQPDAPGRLTQWPSFGQRYTKPNVIPAVQAYAELARKHDLTPTQLALGFARSRWFVASTIIGASSLEQLKET
LPATQTPMSQEILAEIDAIHLRYTNPAP
>Mature_348_residues
MNPFQKNPLGRNHFEVPEVCLGTMTFGEQTSESDAHAQLDFALANGINFIDTAEMYAVPPRAETCGASETIVGHWLKRQA
RDKVLIATKVAGPSRNLNWIRNGPPALDRTNIRAAIDGSLQRLQTDYVDLYQLHWPERNQPMFGQWQFDPDKERDGTPIR
EQLEALGELVREGKIRHIGVSNEHPWGIMQFTRLADELGLPHIVSTQNSYSLLNRTFETGLAEVCHRERVGLLAYSPLAF
GHLTGKYLNQPDAPGRLTQWPSFGQRYTKPNVIPAVQAYAELARKHDLTPTQLALGFARSRWFVASTIIGASSLEQLKET
LPATQTPMSQEILAEIDAIHLRYTNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436962, Length=352, Percent_Identity=29.5454545454545, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI27436964, Length=352, Percent_Identity=29.5454545454545, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI27436966, Length=352, Percent_Identity=29.5454545454545, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4504825, Length=352, Percent_Identity=28.125, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI27436969, Length=347, Percent_Identity=27.9538904899135, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI27436971, Length=344, Percent_Identity=29.0697674418605, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI223718702, Length=328, Percent_Identity=29.8780487804878, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI41327764, Length=324, Percent_Identity=29.9382716049383, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41152114, Length=328, Percent_Identity=28.0487804878049, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=51.7341040462428, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI87081735, Length=345, Percent_Identity=33.3333333333333, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1788070, Length=343, Percent_Identity=30.0291545189504, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789375, Length=344, Percent_Identity=29.3604651162791, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788081, Length=337, Percent_Identity=27.5964391691395, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6325169, Length=353, Percent_Identity=24.929178470255, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=308, Percent_Identity=24.3506493506494, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=338, Percent_Identity=23.6686390532544, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319951, Length=326, Percent_Identity=23.3128834355828, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322615, Length=271, Percent_Identity=21.4022140221402, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324694, Length=237, Percent_Identity=26.5822784810127, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39041; Mature: 39041

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFQKNPLGRNHFEVPEVCLGTMTFGEQTSESDAHAQLDFALANGINFIDTAEMYAVPP
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHEEHHHHHCCCCCEECHHHEECCC
RAETCGASETIVGHWLKRQARDKVLIATKVAGPSRNLNWIRNGPPALDRTNIRAAIDGSL
CHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
QRLQTDYVDLYQLHWPERNQPMFGQWQFDPDKERDGTPIREQLEALGELVREGKIRHIGV
HHHHHHHHHHHHEECCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECC
SNEHPWGIMQFTRLADELGLPHIVSTQNSYSLLNRTFETGLAEVCHRERVGLLAYSPLAF
CCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHH
GHLTGKYLNQPDAPGRLTQWPSFGQRYTKPNVIPAVQAYAELARKHDLTPTQLALGFARS
HHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RWFVASTIIGASSLEQLKETLPATQTPMSQEILAEIDAIHLRYTNPAP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCC
>Mature Secondary Structure
MNPFQKNPLGRNHFEVPEVCLGTMTFGEQTSESDAHAQLDFALANGINFIDTAEMYAVPP
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHEEHHHHHCCCCCEECHHHEECCC
RAETCGASETIVGHWLKRQARDKVLIATKVAGPSRNLNWIRNGPPALDRTNIRAAIDGSL
CHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
QRLQTDYVDLYQLHWPERNQPMFGQWQFDPDKERDGTPIREQLEALGELVREGKIRHIGV
HHHHHHHHHHHHEECCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECC
SNEHPWGIMQFTRLADELGLPHIVSTQNSYSLLNRTFETGLAEVCHRERVGLLAYSPLAF
CCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHH
GHLTGKYLNQPDAPGRLTQWPSFGQRYTKPNVIPAVQAYAELARKHDLTPTQLALGFARS
HHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RWFVASTIIGASSLEQLKETLPATQTPMSQEILAEIDAIHLRYTNPAP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]