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The map label for this gene is acoR [H]

Identifier: 71906639

GI number: 71906639

Start: 1092748

End: 1094733

Strand: Reverse

Name: acoR [H]

Synonym: Daro_1000

Alternate gene names: 71906639

Gene position: 1094733-1092748 (Counterclockwise)

Preceding gene: 71906645

Following gene: 71906630

Centisome position: 24.32

GC content: 63.85

Gene sequence:

>1986_bases
ATGGGACAAATTCAAATGCTGGCCGAAGTCCATGACCAGCGCCTGCAACAGGCAAGGCAACTATTCTTTGATCAGGGCGG
CTTGCCCGAGGGTCTGATCGACCCGCTGATTCTCCGTTCGTGGGAGCGCTGTCGGCGCTTTGGTCTGGGCGAACTCAGCC
TGACACCGGCCACCGAAGCAATGGATCGCGTCGCCCTGAAAACCGAACAGGATCGCAACCGTTATCTGCTGATGCAGGGC
CGGCCGATCATGGAGCATGTCTTCGAGCAGATTCGCGACTCGGGCAGCATGGTCATCCTGGCCGACGCCAACGGCCTGCT
GCTGGAAACCGTCGGCGACCCGGAATTCGTCAACCGGGCTGATCGTGTCGCACTGTCCGCCGGCGCCTCGTGGGATGAAA
ACCTGCGCGGCACCAATGCCATCGGCACCGCGCTTTCCGAAGAAGCCCCGGTCGCCGTCCTTGGCGGCGAACACTTCATC
GAACACAACGGCTTCCTGACCTGCTGCGCCAGCCCCATCTTCGGTCCGGATGGGCGTCTGATCGGCGTCCTCGACATTTC
CGGCGACTACCGCAGCCATCAACGCCACACGCTGGGCCTGGTCCGCCTGTCCTCGGCCATTGTCGAAAAGCGCCTGTTCG
AATCGATTCACGCCCGCGACATCCTGGTCTGCTTCCATAGCCGCCCCGACTATCTGGGCAGCCCGAAGGAAGGCATCGCC
GCCGTTTCGCCGGATGGTCAGGTACTGGCGATCAATCGCAACGGCACCGAGATTCTCGGCATCCGCCAGGTCGACGCCGT
GCGCCGCGATTTCTCCATGGTCTTCGAGAGCAACCTGTCCGCCCTTGTCGACCGTCTGCGCCACAACTCTCAGGGCACCT
GCGAAATCAATGTCAGCGGCAAGGTCATCAACGTCCAGCTGCGCGGTCAGTTGCCGCCGCTGGCCGTGGCCGGGCGTGTT
TTCGACGAGCCCCTGCCGCAACGCGCGCCGCGCCGCGCCGAAACCGCGGCCGCACCAACGCTGACGCTGGACACCCTGAA
CACCGGCGACCCCCGCCTGCAGGCGGCCATCGACCGCGCCCGCCGCATGCTGGGTCGCGACATCCCCATCCTGATCCAGG
GCGAATCCGGCGCCGGCAAGGAAATGTTCGCCAAGGGCTACCACAACAGCGGCCCGCGTCGTGACCAGGCCTTCGTCGCG
CTCAACTGCGCCTCCATTCCGGAAACCCTGATCGAATCGGAACTTTTCGGCTATCAGGGCGGCGCCTTTACCGGCGCCCG
CAAGGAAGGCGCCCCGGGCAAGATTCAGCAGGCCCATGGCGGCACGCTGTTCCTCGATGAAATCGGCGACATGCCGCTCA
ACCTGCAGGCCCGCCTGCTACGCGTGCTGCAGGAACGCTGCGTGACACCTTTGGGCAGCACACGTTCGATCCAGGTCGAT
ATCTCGCTGGTCTGTGCCACGCACCGCAAACTACGCGAAGAAGTCGCCCGCGGCACCTTCCGCGAAGATCTCTATTACCG
CCTGAACGGCATGAGCGTTACCCTGCCCGCCCTGCGCGAACGAACCGACATCCGTTCCATGGTCGCCAAACTGGCTGCTG
TCGAAATCGCCGCACGTGGTGGTCCGGTCAAGTTTTCCGAAGGCGCGCTGCAAGCTATCGAAGGGTACAGCTGGCCGGGC
AATATCCGCCAGCTGTTCAACGTCATCCGCGTCGCCATTGCGCTACTCGACGATGATGAAACCCTGATCACCGAAAGCCA
TCTGCCGGAAGAACTGTTCGAATCCTCCCCGCTCGCCGCGACCGCCAGCGTTCCAGCCTACGACCCATGGGCCGCCGCAC
CTCTCGAAGGCGCCAACAGCATGGATGCGATCAGCCGCCAAGCTGCGATGCGAGCACTGGAAGCAGCCGGCGGCAACATT
TCGTCGGCGGCCCGCCAACTCGGCATCAGCCGCAACACGCTGTACCGCAAGCTGGGACGGATGTAG

Upstream 100 bases:

>100_bases
CTGCAGCGCACTGCTCGCTTCATTGCTTATAAAAAGGGCAGGTGTTACGTTATGAAGCAACAAAACAACAACGATAAATT
CTGGGTGTACCGGAGGCGAG

Downstream 100 bases:

>100_bases
AAGCCACCGATGCGCCTGCCAAGGTGGGCGCATCGCGATCTATCGGTCAGAGGAAAACCAGCGGGTTACGGGTCAGCGCC
ACGCTAACGATATAAACGTA

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MGQIQMLAEVHDQRLQQARQLFFDQGGLPEGLIDPLILRSWERCRRFGLGELSLTPATEAMDRVALKTEQDRNRYLLMQG
RPIMEHVFEQIRDSGSMVILADANGLLLETVGDPEFVNRADRVALSAGASWDENLRGTNAIGTALSEEAPVAVLGGEHFI
EHNGFLTCCASPIFGPDGRLIGVLDISGDYRSHQRHTLGLVRLSSAIVEKRLFESIHARDILVCFHSRPDYLGSPKEGIA
AVSPDGQVLAINRNGTEILGIRQVDAVRRDFSMVFESNLSALVDRLRHNSQGTCEINVSGKVINVQLRGQLPPLAVAGRV
FDEPLPQRAPRRAETAAAPTLTLDTLNTGDPRLQAAIDRARRMLGRDIPILIQGESGAGKEMFAKGYHNSGPRRDQAFVA
LNCASIPETLIESELFGYQGGAFTGARKEGAPGKIQQAHGGTLFLDEIGDMPLNLQARLLRVLQERCVTPLGSTRSIQVD
ISLVCATHRKLREEVARGTFREDLYYRLNGMSVTLPALRERTDIRSMVAKLAAVEIAARGGPVKFSEGALQAIEGYSWPG
NIRQLFNVIRVAIALLDDDETLITESHLPEELFESSPLAATASVPAYDPWAAAPLEGANSMDAISRQAAMRALEAAGGNI
SSAARQLGISRNTLYRKLGRM

Sequences:

>Translated_661_residues
MGQIQMLAEVHDQRLQQARQLFFDQGGLPEGLIDPLILRSWERCRRFGLGELSLTPATEAMDRVALKTEQDRNRYLLMQG
RPIMEHVFEQIRDSGSMVILADANGLLLETVGDPEFVNRADRVALSAGASWDENLRGTNAIGTALSEEAPVAVLGGEHFI
EHNGFLTCCASPIFGPDGRLIGVLDISGDYRSHQRHTLGLVRLSSAIVEKRLFESIHARDILVCFHSRPDYLGSPKEGIA
AVSPDGQVLAINRNGTEILGIRQVDAVRRDFSMVFESNLSALVDRLRHNSQGTCEINVSGKVINVQLRGQLPPLAVAGRV
FDEPLPQRAPRRAETAAAPTLTLDTLNTGDPRLQAAIDRARRMLGRDIPILIQGESGAGKEMFAKGYHNSGPRRDQAFVA
LNCASIPETLIESELFGYQGGAFTGARKEGAPGKIQQAHGGTLFLDEIGDMPLNLQARLLRVLQERCVTPLGSTRSIQVD
ISLVCATHRKLREEVARGTFREDLYYRLNGMSVTLPALRERTDIRSMVAKLAAVEIAARGGPVKFSEGALQAIEGYSWPG
NIRQLFNVIRVAIALLDDDETLITESHLPEELFESSPLAATASVPAYDPWAAAPLEGANSMDAISRQAAMRALEAAGGNI
SSAARQLGISRNTLYRKLGRM
>Mature_660_residues
GQIQMLAEVHDQRLQQARQLFFDQGGLPEGLIDPLILRSWERCRRFGLGELSLTPATEAMDRVALKTEQDRNRYLLMQGR
PIMEHVFEQIRDSGSMVILADANGLLLETVGDPEFVNRADRVALSAGASWDENLRGTNAIGTALSEEAPVAVLGGEHFIE
HNGFLTCCASPIFGPDGRLIGVLDISGDYRSHQRHTLGLVRLSSAIVEKRLFESIHARDILVCFHSRPDYLGSPKEGIAA
VSPDGQVLAINRNGTEILGIRQVDAVRRDFSMVFESNLSALVDRLRHNSQGTCEINVSGKVINVQLRGQLPPLAVAGRVF
DEPLPQRAPRRAETAAAPTLTLDTLNTGDPRLQAAIDRARRMLGRDIPILIQGESGAGKEMFAKGYHNSGPRRDQAFVAL
NCASIPETLIESELFGYQGGAFTGARKEGAPGKIQQAHGGTLFLDEIGDMPLNLQARLLRVLQERCVTPLGSTRSIQVDI
SLVCATHRKLREEVARGTFREDLYYRLNGMSVTLPALRERTDIRSMVAKLAAVEIAARGGPVKFSEGALQAIEGYSWPGN
IRQLFNVIRVAIALLDDDETLITESHLPEELFESSPLAATASVPAYDPWAAAPLEGANSMDAISRQAAMRALEAAGGNIS
SAARQLGISRNTLYRKLGRM

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=344, Percent_Identity=40.1162790697674, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1789233, Length=510, Percent_Identity=31.3725490196078, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1790437, Length=293, Percent_Identity=43.3447098976109, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI1790299, Length=325, Percent_Identity=42.4615384615385, Blast_Score=210, Evalue=3e-55,
Organism=Escherichia coli, GI1788550, Length=294, Percent_Identity=40.8163265306122, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1786524, Length=310, Percent_Identity=41.2903225806452, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789087, Length=300, Percent_Identity=39.6666666666667, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI87082117, Length=305, Percent_Identity=39.672131147541, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI87082152, Length=297, Percent_Identity=38.7205387205387, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1787583, Length=315, Percent_Identity=35.2380952380952, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI87081858, Length=645, Percent_Identity=25.1162790697674, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI87081872, Length=210, Percent_Identity=42.8571428571429, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1789828, Length=511, Percent_Identity=30.5283757338552, Blast_Score=148, Evalue=9e-37,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72183; Mature: 72052

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQIQMLAEVHDQRLQQARQLFFDQGGLPEGLIDPLILRSWERCRRFGLGELSLTPATEA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCHHHH
MDRVALKTEQDRNRYLLMQGRPIMEHVFEQIRDSGSMVILADANGLLLETVGDPEFVNRA
HHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHHCHH
DRVALSAGASWDENLRGTNAIGTALSEEAPVAVLGGEHFIEHNGFLTCCASPIFGPDGRL
HHEEEECCCCCCCCCCCCCHHHHHHCCCCCEEEECCCEEEECCCEEEEECCCCCCCCCCE
IGVLDISGDYRSHQRHTLGLVRLSSAIVEKRLFESIHARDILVCFHSRPDYLGSPKEGIA
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCE
AVSPDGQVLAINRNGTEILGIRQVDAVRRDFSMVFESNLSALVDRLRHNSQGTCEINVSG
EECCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECC
KVINVQLRGQLPPLAVAGRVFDEPLPQRAPRRAETAAAPTLTLDTLNTGDPRLQAAIDRA
EEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHH
RRMLGRDIPILIQGESGAGKEMFAKGYHNSGPRRDQAFVALNCASIPETLIESELFGYQG
HHHHCCCCCEEEECCCCCCHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCC
GAFTGARKEGAPGKIQQAHGGTLFLDEIGDMPLNLQARLLRVLQERCVTPLGSTRSIQVD
CCCCCCCCCCCCCCEEECCCCEEEEHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEE
ISLVCATHRKLREEVARGTFREDLYYRLNGMSVTLPALRERTDIRSMVAKLAAVEIAARG
EEEEHHHHHHHHHHHHHCCHHHHHHEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
GPVKFSEGALQAIEGYSWPGNIRQLFNVIRVAIALLDDDETLITESHLPEELFESSPLAA
CCCEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHCCCCCEE
TASVPAYDPWAAAPLEGANSMDAISRQAAMRALEAAGGNISSAARQLGISRNTLYRKLGR
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCC
M
C
>Mature Secondary Structure 
GQIQMLAEVHDQRLQQARQLFFDQGGLPEGLIDPLILRSWERCRRFGLGELSLTPATEA
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCHHHH
MDRVALKTEQDRNRYLLMQGRPIMEHVFEQIRDSGSMVILADANGLLLETVGDPEFVNRA
HHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHHCHH
DRVALSAGASWDENLRGTNAIGTALSEEAPVAVLGGEHFIEHNGFLTCCASPIFGPDGRL
HHEEEECCCCCCCCCCCCCHHHHHHCCCCCEEEECCCEEEECCCEEEEECCCCCCCCCCE
IGVLDISGDYRSHQRHTLGLVRLSSAIVEKRLFESIHARDILVCFHSRPDYLGSPKEGIA
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCE
AVSPDGQVLAINRNGTEILGIRQVDAVRRDFSMVFESNLSALVDRLRHNSQGTCEINVSG
EECCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECC
KVINVQLRGQLPPLAVAGRVFDEPLPQRAPRRAETAAAPTLTLDTLNTGDPRLQAAIDRA
EEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHH
RRMLGRDIPILIQGESGAGKEMFAKGYHNSGPRRDQAFVALNCASIPETLIESELFGYQG
HHHHCCCCCEEEECCCCCCHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCC
GAFTGARKEGAPGKIQQAHGGTLFLDEIGDMPLNLQARLLRVLQERCVTPLGSTRSIQVD
CCCCCCCCCCCCCCEEECCCCEEEEHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEE
ISLVCATHRKLREEVARGTFREDLYYRLNGMSVTLPALRERTDIRSMVAKLAAVEIAARG
EEEEHHHHHHHHHHHHHCCHHHHHHEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
GPVKFSEGALQAIEGYSWPGNIRQLFNVIRVAIALLDDDETLITESHLPEELFESSPLAA
CCCEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHCCCCCEE
TASVPAYDPWAAAPLEGANSMDAISRQAAMRALEAAGGNISSAARQLGISRNTLYRKLGR
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCC
M
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]