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The map label for this gene is hldE [H]

Identifier: 71906126

GI number: 71906126

Start: 549288

End: 549776

Strand: Reverse

Name: hldE [H]

Synonym: Daro_0486

Alternate gene names: 71906126

Gene position: 549776-549288 (Counterclockwise)

Preceding gene: 71906127

Following gene: 71906121

Centisome position: 12.21

GC content: 63.8

Gene sequence:

>489_bases
ATGTCCTACGCCTCCCCTTCCTTCGAATCGAAAATCTGCCCGCCGCACCAGCTGGCTGCCAGAGCCGCCCAGTTAGACCA
CCCGCTGGTGTTCACCAACGGCTGTTTCGACATCCTGCACCGTGGCCATGTGACCTACCTGGCCCAGGCGGCCGCTCTCG
GCACGAGCATGGTCGTCGCGCTGAATACCGATGCCTCGGTCAAGCGTCTGGGGAAGGGCGACGACCGTCCGGTCAATGCG
CTGGAAGACCGCCTGGCGGTCATGGCCTCGCTGGCCTGCGTTTCGCTGGTCACCTGGTTCGATGAAGATACGCCGCTACA
ACGCATCCTCGAATGCCGCCCCGACATCCTGGTCAAGGGCGGCGACTGGCCGGTGGACAAGATCGTTGGCTGCAGCGAAG
TCCGCGGCTGGGGTGGCACGGTGCATTCGATCCCCTTCATCCACCAGACATCGACGACGGCGCTACTGGAAAAGATCCGC
CGCCTCTGA

Upstream 100 bases:

>100_bases
ACCGGATTGCGCAGCAACCAGGCCGAACAGCAAGAATGCTTAATTTGATGCTCGGCCAACAGGCACTAAAATAGACACTT
ACTCCATTCGTAAAGCAGCC

Downstream 100 bases:

>100_bases
GGGCTGCATATCGCCAAGCGCGACAGACATCAGCCAGCCCAAACCGGTCCTGACAGAGAATAGAAATTCGCCAGCGGATG
GCCGCTGGCGCTGGCGGTCG

Product: cytidyltransferase-related

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSYASPSFESKICPPHQLAARAAQLDHPLVFTNGCFDILHRGHVTYLAQAAALGTSMVVALNTDASVKRLGKGDDRPVNA
LEDRLAVMASLACVSLVTWFDEDTPLQRILECRPDILVKGGDWPVDKIVGCSEVRGWGGTVHSIPFIHQTSTTALLEKIR
RL

Sequences:

>Translated_162_residues
MSYASPSFESKICPPHQLAARAAQLDHPLVFTNGCFDILHRGHVTYLAQAAALGTSMVVALNTDASVKRLGKGDDRPVNA
LEDRLAVMASLACVSLVTWFDEDTPLQRILECRPDILVKGGDWPVDKIVGCSEVRGWGGTVHSIPFIHQTSTTALLEKIR
RL
>Mature_161_residues
SYASPSFESKICPPHQLAARAAQLDHPLVFTNGCFDILHRGHVTYLAQAAALGTSMVVALNTDASVKRLGKGDDRPVNAL
EDRLAVMASLACVSLVTWFDEDTPLQRILECRPDILVKGGDWPVDKIVGCSEVRGWGGTVHSIPFIHQTSTTALLEKIRR
L

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=142, Percent_Identity=49.2957746478873, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 17664; Mature: 17532

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYASPSFESKICPPHQLAARAAQLDHPLVFTNGCFDILHRGHVTYLAQAAALGTSMVVA
CCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHHHHHCCHHHHHHHHHHHCCEEEEE
LNTDASVKRLGKGDDRPVNALEDRLAVMASLACVSLVTWFDEDTPLQRILECRPDILVKG
ECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEC
GDWPVDKIVGCSEVRGWGGTVHSIPFIHQTSTTALLEKIRRL
CCCCHHHHCCHHHHCCCCCCCCCCCCEECCHHHHHHHHHHCC
>Mature Secondary Structure 
SYASPSFESKICPPHQLAARAAQLDHPLVFTNGCFDILHRGHVTYLAQAAALGTSMVVA
CCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHHHHHCCHHHHHHHHHHHCCEEEEE
LNTDASVKRLGKGDDRPVNALEDRLAVMASLACVSLVTWFDEDTPLQRILECRPDILVKG
ECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEC
GDWPVDKIVGCSEVRGWGGTVHSIPFIHQTSTTALLEKIRRL
CCCCHHHHCCHHHHCCCCCCCCCCCCEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA