Click here to switch to the map view.

The map label for this gene is prpC [H]

Identifier: 71906077

GI number: 71906077

Start: 479421

End: 480311

Strand: Reverse

Name: prpC [H]

Synonym: Daro_0437

Alternate gene names: 71906077

Gene position: 480311-479421 (Counterclockwise)

Preceding gene: 71906080

Following gene: 71906076

Centisome position: 10.67

GC content: 60.83

Gene sequence:

>891_bases
GTGTCAAGAAAGGCAAAACCGATATGCTATATTTCAGCGCGTTTTCCCGCTCCTCACTGGCTTTTCGCTGACAAATTGAA
CAAACAACGCTTTTCCCTCGAAGCCATCGCCCTTTCCGATCCCGGCCGGATGCGCGCACTCAATGAAGACGCCGTTGCCG
TCGATGTCGAGTACGGATTCGCCGTCGTCGCCGACGGCATGGGCGGCCACAACGCAGGAGAAATCGCCAGCCGGATCGCC
GTCGACACCCTCCGCGAACGCCTGCCGATCAAGATCCAGCAATTTCGCGCCGGCGCACGCCAGCCGCGACCACATCAGTT
CGCCGAGCAGTTAATCGGCGAGGCCAACCGTGCCATCTACTCCACGGCGGCCGGCCACGCGAACTGCAAGGGCATGGGCA
CAACCATCGCGCTCTGGCTGATGCATGGTGAGCATGCCGCGCTGCTGCATATCGGCGACTCACGCATCTACCGCCTGCGC
AACGGCCAATTGCAGCAACTGACCCGCGACGACTCGCTGCTCCGTGATCAGGTCGAAAGTGGGCTGATTTCGGCCAACGA
AGCCGCCAGCTCGCACAACCGGCACTTCGTTACACGCGCCCTCGGCCTCGAGCTGCAAACCGCAGTTCATATCCACGAAG
AAGCCCTACGGGCCGGCGACCTTTACCTGCTCTGCTCCGACGGCTTGACCGACATGGTCGAGGACAGCGACATCGAGCTG
ATTCTGGACCAGCTAAAAACCAATCTGGAATTGGCTGCCCAACACCTGATCCAGCTCGCCAACGACTACGGCGGAGCCGA
CAACATCTCGGTGGCACTCGTGCGCGTTTTTGATACGGCGCCGGAAAAATCCGGCCTGCTCGGTCGCCTGCTAAGCTGGC
TGAAGCGCTGA

Upstream 100 bases:

>100_bases
GATCTTGAATCGCCCCAGTTGTTCGATTGCCATGTCAAAAAATGCCGATGTAATATACCGCGTGCGGACGAGGGTTGAAT
ATCGTCTACCGGGATAGATA

Downstream 100 bases:

>100_bases
AGGGGAGACAGAATCATGGCAAAACTCGTGCTCAGCCTGAACGGCACCGTGATCAACCAGTTTTTTACCGACAAGCCCAA
CCTCTGCATCGGGCAGGCTG

Product: protein phosphatase 2C-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSRKAKPICYISARFPAPHWLFADKLNKQRFSLEAIALSDPGRMRALNEDAVAVDVEYGFAVVADGMGGHNAGEIASRIA
VDTLRERLPIKIQQFRAGARQPRPHQFAEQLIGEANRAIYSTAAGHANCKGMGTTIALWLMHGEHAALLHIGDSRIYRLR
NGQLQQLTRDDSLLRDQVESGLISANEAASSHNRHFVTRALGLELQTAVHIHEEALRAGDLYLLCSDGLTDMVEDSDIEL
ILDQLKTNLELAAQHLIQLANDYGGADNISVALVRVFDTAPEKSGLLGRLLSWLKR

Sequences:

>Translated_296_residues
MSRKAKPICYISARFPAPHWLFADKLNKQRFSLEAIALSDPGRMRALNEDAVAVDVEYGFAVVADGMGGHNAGEIASRIA
VDTLRERLPIKIQQFRAGARQPRPHQFAEQLIGEANRAIYSTAAGHANCKGMGTTIALWLMHGEHAALLHIGDSRIYRLR
NGQLQQLTRDDSLLRDQVESGLISANEAASSHNRHFVTRALGLELQTAVHIHEEALRAGDLYLLCSDGLTDMVEDSDIEL
ILDQLKTNLELAAQHLIQLANDYGGADNISVALVRVFDTAPEKSGLLGRLLSWLKR
>Mature_295_residues
SRKAKPICYISARFPAPHWLFADKLNKQRFSLEAIALSDPGRMRALNEDAVAVDVEYGFAVVADGMGGHNAGEIASRIAV
DTLRERLPIKIQQFRAGARQPRPHQFAEQLIGEANRAIYSTAAGHANCKGMGTTIALWLMHGEHAALLHIGDSRIYRLRN
GQLQQLTRDDSLLRDQVESGLISANEAASSHNRHFVTRALGLELQTAVHIHEEALRAGDLYLLCSDGLTDMVEDSDIELI
LDQLKTNLELAAQHLIQLANDYGGADNISVALVRVFDTAPEKSGLLGRLLSWLKR

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 32616; Mature: 32484

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKAKPICYISARFPAPHWLFADKLNKQRFSLEAIALSDPGRMRALNEDAVAVDVEYGF
CCCCCCCEEEEEECCCCCCCHHHHHHCCHHEEEEEEEECCCCHHEECCCCCEEEEEECCE
AVVADGMGGHNAGEIASRIAVDTLRERLPIKIQQFRAGARQPRPHQFAEQLIGEANRAIY
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHE
STAAGHANCKGMGTTIALWLMHGEHAALLHIGDSRIYRLRNGQLQQLTRDDSLLRDQVES
EECCCCCCCCCCCCEEEEEEEECCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHH
GLISANEAASSHNRHFVTRALGLELQTAVHIHEEALRAGDLYLLCSDGLTDMVEDSDIEL
CCCCCCHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCHHHH
ILDQLKTNLELAAQHLIQLANDYGGADNISVALVRVFDTAPEKSGLLGRLLSWLKR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SRKAKPICYISARFPAPHWLFADKLNKQRFSLEAIALSDPGRMRALNEDAVAVDVEYGF
CCCCCCEEEEEECCCCCCCHHHHHHCCHHEEEEEEEECCCCHHEECCCCCEEEEEECCE
AVVADGMGGHNAGEIASRIAVDTLRERLPIKIQQFRAGARQPRPHQFAEQLIGEANRAIY
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHE
STAAGHANCKGMGTTIALWLMHGEHAALLHIGDSRIYRLRNGQLQQLTRDDSLLRDQVES
EECCCCCCCCCCCCEEEEEEEECCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHH
GLISANEAASSHNRHFVTRALGLELQTAVHIHEEALRAGDLYLLCSDGLTDMVEDSDIEL
CCCCCCHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCHHHH
ILDQLKTNLELAAQHLIQLANDYGGADNISVALVRVFDTAPEKSGLLGRLLSWLKR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]