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The map label for this gene is nhaR [H]

Identifier: 71905934

GI number: 71905934

Start: 333418

End: 334326

Strand: Reverse

Name: nhaR [H]

Synonym: Daro_0292

Alternate gene names: 71905934

Gene position: 334326-333418 (Counterclockwise)

Preceding gene: 71905941

Following gene: 71905933

Centisome position: 7.43

GC content: 64.58

Gene sequence:

>909_bases
ATGACGCCACTTAACTACAAGCATCTTCATTACTTCTGGGTCGTCGCCCAGGAAGGCAGCATCACCCGAGCCGCCGAGCG
ACTCGATGTCGCCGTTCAGACCATCAGCGGCCAGCTTTCCCTGCTTGAACGCCATCTGGGCAAAGCGCTGTTCAACAGCC
AGGGACGCGGCCTGGTACTGAGCGAGGCCGGCCGCGTCGCACTCGGTTACGCCGACCAGATATTCCAGCTCGGCGACGCG
CTGGTCGACGCCGTGGAGCACAGCAACAGCGAGTCCACGCTTCGCCTGCGCGCCGGCATTTCCGACGGCATTCCCAAGCT
GCTAGCCTATCGACTGCTGTCGACGGTGACCGACATGCCGGCCGATGTCCGCTTGATTTGCGATGAAGGCGAATTCGAAA
CCCTGTTGGCCGATCTCGCCCTGCACCGCCTCGATGTGGTGCTGACCGATCGCTCTGCCCCGGTCGGTGGCAATCTGAAG
GTGTTCAGCACCCGGCTGGGCGAATTCGCCACCGGACTATTCGCCACACCGGCCCTCGTCGAGCGTTATCAGCCGGACTT
CCCGAACAGCCTCGACGGTGCGCCGATGCTGTTGCCGACTCGCCACAACGCCCTGCGTGGCCGGATTGATCGCTGGCTGG
AGAACACCAACATTCGTCCGAAGATCGTCGGCGAATTTGAAGACAGCGCGCTACTCAACACCTTCGGCCGCGGCGGCCTG
GGGATATTCCCGGCCCCGCTCGGCCTGGCCGAACAGATTGCCTCGCAACTCGATGCCCAGCCACTGGGCGCCATGGCCGG
CGTCAGCGAACAGATCTACGCGATCTCCAGCGAACGGCGCATCCGCCACCCGGCCGTCGAGGCGCTCTGCGCCGCAGCGC
CGCAGGCCGGCGCGGAGCCGAGGGTATAA

Upstream 100 bases:

>100_bases
CGAACTCCTCAAAAGACAAACGGGCCAATGGTATGGCGTTGCACAAAATTAAAAAACAGGAGCAAAATTGACTATTACTT
CGATTTTTCCTGACAAACCA

Downstream 100 bases:

>100_bases
TGTCCTCCCCCAACGCAAAACAAAGTACAAACCCCATGTCGCTGTTCCGCAAGACCGCTTTCATCCTCCTCAGTATTGTC
ACCGCTGGCCAGGCCATGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTPLNYKHLHYFWVVAQEGSITRAAERLDVAVQTISGQLSLLERHLGKALFNSQGRGLVLSEAGRVALGYADQIFQLGDA
LVDAVEHSNSESTLRLRAGISDGIPKLLAYRLLSTVTDMPADVRLICDEGEFETLLADLALHRLDVVLTDRSAPVGGNLK
VFSTRLGEFATGLFATPALVERYQPDFPNSLDGAPMLLPTRHNALRGRIDRWLENTNIRPKIVGEFEDSALLNTFGRGGL
GIFPAPLGLAEQIASQLDAQPLGAMAGVSEQIYAISSERRIRHPAVEALCAAAPQAGAEPRV

Sequences:

>Translated_302_residues
MTPLNYKHLHYFWVVAQEGSITRAAERLDVAVQTISGQLSLLERHLGKALFNSQGRGLVLSEAGRVALGYADQIFQLGDA
LVDAVEHSNSESTLRLRAGISDGIPKLLAYRLLSTVTDMPADVRLICDEGEFETLLADLALHRLDVVLTDRSAPVGGNLK
VFSTRLGEFATGLFATPALVERYQPDFPNSLDGAPMLLPTRHNALRGRIDRWLENTNIRPKIVGEFEDSALLNTFGRGGL
GIFPAPLGLAEQIASQLDAQPLGAMAGVSEQIYAISSERRIRHPAVEALCAAAPQAGAEPRV
>Mature_301_residues
TPLNYKHLHYFWVVAQEGSITRAAERLDVAVQTISGQLSLLERHLGKALFNSQGRGLVLSEAGRVALGYADQIFQLGDAL
VDAVEHSNSESTLRLRAGISDGIPKLLAYRLLSTVTDMPADVRLICDEGEFETLLADLALHRLDVVLTDRSAPVGGNLKV
FSTRLGEFATGLFATPALVERYQPDFPNSLDGAPMLLPTRHNALRGRIDRWLENTNIRPKIVGEFEDSALLNTFGRGGLG
IFPAPLGLAEQIASQLDAQPLGAMAGVSEQIYAISSERRIRHPAVEALCAAAPQAGAEPRV

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=302, Percent_Identity=34.4370860927152, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1788297, Length=244, Percent_Identity=24.5901639344262, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32685; Mature: 32554

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLNYKHLHYFWVVAQEGSITRAAERLDVAVQTISGQLSLLERHLGKALFNSQGRGLVL
CCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
SEAGRVALGYADQIFQLGDALVDAVEHSNSESTLRLRAGISDGIPKLLAYRLLSTVTDMP
ECCCCEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
ADVRLICDEGEFETLLADLALHRLDVVLTDRSAPVGGNLKVFSTRLGEFATGLFATPALV
CCEEEEECCCHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
ERYQPDFPNSLDGAPMLLPTRHNALRGRIDRWLENTNIRPKIVGEFEDSALLNTFGRGGL
HHCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHCCCCCC
GIFPAPLGLAEQIASQLDAQPLGAMAGVSEQIYAISSERRIRHPAVEALCAAAPQAGAEP
CCCCCCCCHHHHHHHHHCCCCHHHHHCCCHHHEEECCCCHHHHHHHHHHHHHCCCCCCCC
RV
CC
>Mature Secondary Structure 
TPLNYKHLHYFWVVAQEGSITRAAERLDVAVQTISGQLSLLERHLGKALFNSQGRGLVL
CCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
SEAGRVALGYADQIFQLGDALVDAVEHSNSESTLRLRAGISDGIPKLLAYRLLSTVTDMP
ECCCCEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
ADVRLICDEGEFETLLADLALHRLDVVLTDRSAPVGGNLKVFSTRLGEFATGLFATPALV
CCEEEEECCCHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
ERYQPDFPNSLDGAPMLLPTRHNALRGRIDRWLENTNIRPKIVGEFEDSALLNTFGRGGL
HHCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHCCCCCC
GIFPAPLGLAEQIASQLDAQPLGAMAGVSEQIYAISSERRIRHPAVEALCAAAPQAGAEP
CCCCCCCCHHHHHHHHHCCCCHHHHHCCCHHHEEECCCCHHHHHHHHHHHHHCCCCCCCC
RV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]