Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 71905866

GI number: 71905866

Start: 248540

End: 249271

Strand: Reverse

Name: ompR [H]

Synonym: Daro_0224

Alternate gene names: 71905866

Gene position: 249271-248540 (Counterclockwise)

Preceding gene: 71905867

Following gene: 71905865

Centisome position: 5.54

GC content: 63.93

Gene sequence:

>732_bases
ATGAAAGACAACGAATCCGCCAAGCTGATCGCCATTGTCGAGGACGATCCCGATGTCGCCAAGATCATTGAGCAGGTGCT
CGGCGACTTCGGTTTCCGCACCTGCTGGTGTCGCAGCGCCGGCGACCTGCTGCGCCGCCTGCGCACCCTGGCGCCGGACT
TGTGCATTATCGATCTCGGACTGCCGGACATGGATGGCCTCGAAGCCATGCAGCGGGTACGCGCCCAGTCTGGCTGCGGC
ATCCTGATCCTGACCGGACGGGCCCACGTCAGCGACCGCGTCATGGGCCTTGAACTCGGGGCTGACGATTACGTTCTGAA
ACCGTTCGAGCCGCGCGAACTGGTCGCCCGGGTGCGCAGCATCGTACGCCGGCGTGAGAGCAGCGAAACACCCGCCCGCC
AGATTGCCGAGTTCGGCGGCTGGCGCTTCAACCTGAGCAACAATCGGCTCACCGCACCAAACGGCGACGAACTTGCCCTC
AGCACGGCCGAATCCGAATTGCTGAAGGTCTTCGTCAGCCATCCGAACCGCATCCTGCAACGCGAAAAACTGATGGGATC
GCGCGACCTTGCCCCCAGCGACCGCGCCATCGATGTCCGCATCTCGCGCCTGCGCCGCAAGCTCGAACCCGATCCGCAAA
GCCCGGCTTTTCTCAAGACGGTCTACGGCGCTGGCTATCTGTTTCTGGCCGCGGTCTCCTGGTCCGGTGAACCCGGCGCT
AGCCAGCACTGA

Upstream 100 bases:

>100_bases
AAGCCGAAACAGATGGCACCAGTGCGCTGCCCATTCTCGCCAAACCATTCGACCGCCAGGATCTGGCTCGCGCCCTGCAA
AGCGCACACCGAGGCACGCC

Downstream 100 bases:

>100_bases
GTACCCGCAACGCGCCTTTCCTCGGTTTTCTGTCTGCACTTTTTCCCGACAAAGTATTGAAGCCCCCTGTCGCAATAAAA
CATTGATATATTTGTGTTTT

Product: response regulator receiver:transcriptional regulatory protein, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKDNESAKLIAIVEDDPDVAKIIEQVLGDFGFRTCWCRSAGDLLRRLRTLAPDLCIIDLGLPDMDGLEAMQRVRAQSGCG
ILILTGRAHVSDRVMGLELGADDYVLKPFEPRELVARVRSIVRRRESSETPARQIAEFGGWRFNLSNNRLTAPNGDELAL
STAESELLKVFVSHPNRILQREKLMGSRDLAPSDRAIDVRISRLRRKLEPDPQSPAFLKTVYGAGYLFLAAVSWSGEPGA
SQH

Sequences:

>Translated_243_residues
MKDNESAKLIAIVEDDPDVAKIIEQVLGDFGFRTCWCRSAGDLLRRLRTLAPDLCIIDLGLPDMDGLEAMQRVRAQSGCG
ILILTGRAHVSDRVMGLELGADDYVLKPFEPRELVARVRSIVRRRESSETPARQIAEFGGWRFNLSNNRLTAPNGDELAL
STAESELLKVFVSHPNRILQREKLMGSRDLAPSDRAIDVRISRLRRKLEPDPQSPAFLKTVYGAGYLFLAAVSWSGEPGA
SQH
>Mature_243_residues
MKDNESAKLIAIVEDDPDVAKIIEQVLGDFGFRTCWCRSAGDLLRRLRTLAPDLCIIDLGLPDMDGLEAMQRVRAQSGCG
ILILTGRAHVSDRVMGLELGADDYVLKPFEPRELVARVRSIVRRRESSETPARQIAEFGGWRFNLSNNRLTAPNGDELAL
STAESELLKVFVSHPNRILQREKLMGSRDLAPSDRAIDVRISRLRRKLEPDPQSPAFLKTVYGAGYLFLAAVSWSGEPGA
SQH

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=37.9912663755458, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=32.15859030837, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=37.3913043478261, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=34.061135371179, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=35.2422907488987, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=34.841628959276, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI2367329, Length=245, Percent_Identity=33.8775510204082, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=31.390134529148, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=31.4159292035398, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=32.1266968325792, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=243, Percent_Identity=33.7448559670782, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790552, Length=181, Percent_Identity=34.8066298342541, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=29.7777777777778, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=31.1320754716981, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790437, Length=154, Percent_Identity=27.9220779220779, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27010; Mature: 27010

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDNESAKLIAIVEDDPDVAKIIEQVLGDFGFRTCWCRSAGDLLRRLRTLAPDLCIIDLG
CCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCEEEEECC
LPDMDGLEAMQRVRAQSGCGILILTGRAHVSDRVMGLELGADDYVLKPFEPRELVARVRS
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCEECCCCHHHHHHHHHH
IVRRRESSETPARQIAEFGGWRFNLSNNRLTAPNGDELALSTAESELLKVFVSHPNRILQ
HHHHHCCCCCHHHHHHHHCCEEEEECCCEEECCCCCCEEEHHHHHHHHHHHHHCCHHHHH
REKLMGSRDLAPSDRAIDVRISRLRRKLEPDPQSPAFLKTVYGAGYLFLAAVSWSGEPGA
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCC
SQH
CCC
>Mature Secondary Structure
MKDNESAKLIAIVEDDPDVAKIIEQVLGDFGFRTCWCRSAGDLLRRLRTLAPDLCIIDLG
CCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCEEEEECC
LPDMDGLEAMQRVRAQSGCGILILTGRAHVSDRVMGLELGADDYVLKPFEPRELVARVRS
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCEECCCCHHHHHHHHHH
IVRRRESSETPARQIAEFGGWRFNLSNNRLTAPNGDELALSTAESELLKVFVSHPNRILQ
HHHHHCCCCCHHHHHHHHCCEEEEECCCEEECCCCCCEEEHHHHHHHHHHHHHCCHHHHH
REKLMGSRDLAPSDRAIDVRISRLRRKLEPDPQSPAFLKTVYGAGYLFLAAVSWSGEPGA
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCC
SQH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]