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The map label for this gene is can [H]

Identifier: 71905741

GI number: 71905741

Start: 115726

End: 116889

Strand: Reverse

Name: can [H]

Synonym: Daro_0099

Alternate gene names: 71905741

Gene position: 116889-115726 (Counterclockwise)

Preceding gene: 71905742

Following gene: 71905740

Centisome position: 2.6

GC content: 62.03

Gene sequence:

>1164_bases
ATGGAGCTAAACAGCATGACCGTTACCCTACGCACCCTCACCGCCAACGATAGCGAAGCCCTGGAGCAGGTTCGCCAGTA
CTTCCGCAACTATGCGGCCTGGCTGGGCGTCGACCTGTCGTACCAGAACTTCGATCAGGAAATGGCCTCGCTGCCCGGCA
CCTATGTCGCACCGCAGGGCCGCCTGTTCTTTGCCGAGGTTGATGGTCGCCCGGCCGGCTGTGTCGGCGTTCGCCCGCTG
CCGGACAGCGATGGTGTCTGCGAAATGAAGCGCCTCTATGTCGATCCGGCCGAACGCGGCCACGGGATCGGTGCCGCGCT
GGCGCTGGCCGCGATCAAGGCGGCCAAGGAAATCGGTTTCCGCAAGCTGATGATCGACACCCTGCCCAACATGCGTATGG
CCGTGAAGCTCTACCGCGAACTGGGCTTCACCGAAGCACCGAACTATTACCAGACGCCAGTCGAAGGCACGATGTTCCTC
GCCCTCGATCTGGAAAACTGGTCGGAAGAGGAAATCCGCAGCGAAAACCTGTCGCACCTGTTCGACTTCAACCGCGCCTG
GGCCCGCCAGATGCAGGAAGTTGACCCAACCTACTTCGACCGCCTGTCCCACCTGCAGACACCGGAATTCCTGTGGATCG
GCTGCTCCGATTCGCGCGTCCCGGCCAACCAGATCGTCGGCCTGCTACCGGGCGAGGTCTTCGTCCATCGCAACGTTGCC
AATGTCGTCGTCCATACCGACCTCAACTGCCTGTCGGTCATCCAGTACGCAGTCGATGTGCTGAAGGTCAAGCACATCAT
GGTCGTCGGCCATTACGGCTGCGGCGGCGTCGGCGCAGCATTGCAACGGGACCGGGTCGGCATCGTCGACCTCTGGCTGC
GTCACGTTCATGACGTGCATAACAAGCATCTGGCCAACGTCAACAGCCTGCCGGAAGCGCAACGCCACGACCGCCTTTGC
GAGCTGAACGTACTGGAGCAGGTGGTCAATGTCTGCCACAACCCGGTCGTCCAGGATGCCTGGAGCCGCGGCCAGCAACT
GACCGTCCACGGCTGGGTTTACGGCCTGAAGGACGGCCTGATCCACGACCTCGGCATCACGATCGATTGCCCACAGGATT
TGCCTTCCCGCTACGACGCCGCACTCAAAGCGTTGGACGCCTAG

Upstream 100 bases:

>100_bases
CAGGCACCTCGGAAATCCGTAGAATGCTGATTGGTCGCGAACTCTTCGCTGAAACCGCATAACACGCTCCTGCCGGCGCT
CCGGACAGGAGCGCCGCAAC

Downstream 100 bases:

>100_bases
TTACAACAACCACTCAGGAGAAATCAGCATGAATGACCCGATCGTTATCGTTTCCGCCGCCCGTACCGCCATGGGCGCCT
TTCAGGGCGGCTTTGCCGGC

Product: GCN5-related N-acetyltransferase:carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MELNSMTVTLRTLTANDSEALEQVRQYFRNYAAWLGVDLSYQNFDQEMASLPGTYVAPQGRLFFAEVDGRPAGCVGVRPL
PDSDGVCEMKRLYVDPAERGHGIGAALALAAIKAAKEIGFRKLMIDTLPNMRMAVKLYRELGFTEAPNYYQTPVEGTMFL
ALDLENWSEEEIRSENLSHLFDFNRAWARQMQEVDPTYFDRLSHLQTPEFLWIGCSDSRVPANQIVGLLPGEVFVHRNVA
NVVVHTDLNCLSVIQYAVDVLKVKHIMVVGHYGCGGVGAALQRDRVGIVDLWLRHVHDVHNKHLANVNSLPEAQRHDRLC
ELNVLEQVVNVCHNPVVQDAWSRGQQLTVHGWVYGLKDGLIHDLGITIDCPQDLPSRYDAALKALDA

Sequences:

>Translated_387_residues
MELNSMTVTLRTLTANDSEALEQVRQYFRNYAAWLGVDLSYQNFDQEMASLPGTYVAPQGRLFFAEVDGRPAGCVGVRPL
PDSDGVCEMKRLYVDPAERGHGIGAALALAAIKAAKEIGFRKLMIDTLPNMRMAVKLYRELGFTEAPNYYQTPVEGTMFL
ALDLENWSEEEIRSENLSHLFDFNRAWARQMQEVDPTYFDRLSHLQTPEFLWIGCSDSRVPANQIVGLLPGEVFVHRNVA
NVVVHTDLNCLSVIQYAVDVLKVKHIMVVGHYGCGGVGAALQRDRVGIVDLWLRHVHDVHNKHLANVNSLPEAQRHDRLC
ELNVLEQVVNVCHNPVVQDAWSRGQQLTVHGWVYGLKDGLIHDLGITIDCPQDLPSRYDAALKALDA
>Mature_387_residues
MELNSMTVTLRTLTANDSEALEQVRQYFRNYAAWLGVDLSYQNFDQEMASLPGTYVAPQGRLFFAEVDGRPAGCVGVRPL
PDSDGVCEMKRLYVDPAERGHGIGAALALAAIKAAKEIGFRKLMIDTLPNMRMAVKLYRELGFTEAPNYYQTPVEGTMFL
ALDLENWSEEEIRSENLSHLFDFNRAWARQMQEVDPTYFDRLSHLQTPEFLWIGCSDSRVPANQIVGLLPGEVFVHRNVA
NVVVHTDLNCLSVIQYAVDVLKVKHIMVVGHYGCGGVGAALQRDRVGIVDLWLRHVHDVHNKHLANVNSLPEAQRHDRLC
ELNVLEQVVNVCHNPVVQDAWSRGQQLTVHGWVYGLKDGLIHDLGITIDCPQDLPSRYDAALKALDA

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=211, Percent_Identity=51.6587677725119, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI1786534, Length=170, Percent_Identity=32.3529411764706, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI48995002, Length=136, Percent_Identity=33.8235294117647, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324292, Length=205, Percent_Identity=32.1951219512195, Blast_Score=112, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 43415; Mature: 43415

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELNSMTVTLRTLTANDSEALEQVRQYFRNYAAWLGVDLSYQNFDQEMASLPGTYVAPQG
CCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEECCCC
RLFFAEVDGRPAGCVGVRPLPDSDGVCEMKRLYVDPAERGHGIGAALALAAIKAAKEIGF
CEEEEEECCCCCCEECCCCCCCCCCHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHH
RKLMIDTLPNMRMAVKLYRELGFTEAPNYYQTPVEGTMFLALDLENWSEEEIRSENLSHL
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
FDFNRAWARQMQEVDPTYFDRLSHLQTPEFLWIGCSDSRVPANQIVGLLPGEVFVHRNVA
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCEEEECCCE
NVVVHTDLNCLSVIQYAVDVLKVKHIMVVGHYGCGGVGAALQRDRVGIVDLWLRHVHDVH
EEEEECCCHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
NKHLANVNSLPEAQRHDRLCELNVLEQVVNVCHNPVVQDAWSRGQQLTVHGWVYGLKDGL
HHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEEEEEHHCCC
IHDLGITIDCPQDLPSRYDAALKALDA
EECCCEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELNSMTVTLRTLTANDSEALEQVRQYFRNYAAWLGVDLSYQNFDQEMASLPGTYVAPQG
CCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEECCCC
RLFFAEVDGRPAGCVGVRPLPDSDGVCEMKRLYVDPAERGHGIGAALALAAIKAAKEIGF
CEEEEEECCCCCCEECCCCCCCCCCHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHH
RKLMIDTLPNMRMAVKLYRELGFTEAPNYYQTPVEGTMFLALDLENWSEEEIRSENLSHL
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
FDFNRAWARQMQEVDPTYFDRLSHLQTPEFLWIGCSDSRVPANQIVGLLPGEVFVHRNVA
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCEEEECCCE
NVVVHTDLNCLSVIQYAVDVLKVKHIMVVGHYGCGGVGAALQRDRVGIVDLWLRHVHDVH
EEEEECCCHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
NKHLANVNSLPEAQRHDRLCELNVLEQVVNVCHNPVVQDAWSRGQQLTVHGWVYGLKDGL
HHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEEEEEHHCCC
IHDLGITIDCPQDLPSRYDAALKALDA
EECCCEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]