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The map label for this gene is pyrG [H]

Identifier: 71911423

GI number: 71911423

Start: 1567892

End: 1568044

Strand: Reverse

Name: pyrG [H]

Synonym: M5005_Spy_1610

Alternate gene names: 71911423

Gene position: 1568044-1567892 (Counterclockwise)

Preceding gene: 161936120

Following gene: 71911422

Centisome position: 85.29

GC content: 35.95

Gene sequence:

>153_bases
ATGACGAAATACATTTTTGTAACTGGTGGTGTTGTATCATCAATTGGCAAAGGAATTGTTGCGGCAAGTCTTGGCCGATT
GTTAAAAAATCGTGGACTTAAGGTGACGATTCAAAAATTTGATCCTTATATTAATATTGATCCAGGACGATGA

Upstream 100 bases:

>100_bases
ATATTTAGAAAACTAAGGTGATACCTAACCAATGTGGAACCAACTAATAGGGAATTAACAAGAAAGCAATGCTTTTATTC
AGCTTATATAAAGGAGTACT

Downstream 100 bases:

>100_bases
GCCCCTATCAGCATGGAGAAGTATATGTGACAGATGACGGTGCTGAAACCGACTTGGATTTGGGTCACTATGAACGTTTT
ATTGATATCAATCTTAATAA

Product: CTP synthase

Products: NA

Alternate protein names: CTP synthetase; UTP--ammonia ligase [H]

Number of amino acids: Translated: 50; Mature: 49

Protein sequence:

>50_residues
MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGR

Sequences:

>Translated_50_residues
MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGR
>Mature_49_residues
TKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGR

Specific function: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen [H]

COG id: COG0504

COG function: function code F; CTP synthase (UTP-ammonia lyase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI28559085, Length=47, Percent_Identity=68.0851063829787, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI28559083, Length=47, Percent_Identity=68.0851063829787, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI221316689, Length=47, Percent_Identity=68.0851063829787, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI148491070, Length=47, Percent_Identity=68.0851063829787, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789142, Length=48, Percent_Identity=75, Blast_Score=64, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25148299, Length=47, Percent_Identity=63.8297872340426, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322563, Length=47, Percent_Identity=63.8297872340426, Blast_Score=66, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319432, Length=47, Percent_Identity=61.7021276595745, Blast_Score=65, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24664469, Length=47, Percent_Identity=65.9574468085106, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004468
- InterPro:   IPR017456
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF06418 CTP_synth_N; PF00117 GATase [H]

EC number: =6.3.4.2 [H]

Molecular weight: Translated: 5394; Mature: 5262

Theoretical pI: Translated: 11.02; Mature: 11.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGR
CCEEEEEECCHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCC
>Mature Secondary Structure 
TKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGR
CEEEEEECCHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA