Click here to switch to the map view.

The map label for this gene is gpsA [H]

Identifier: 71910008

GI number: 71910008

Start: 199408

End: 200223

Strand: Reverse

Name: gpsA [H]

Synonym: M5005_Spy_0194

Alternate gene names: 71910008

Gene position: 200223-199408 (Counterclockwise)

Preceding gene: 71910033

Following gene: 71910007

Centisome position: 10.89

GC content: 43.38

Gene sequence:

>816_bases
ATGACAAAACAAAAAGTAGCTATTTTAGGACCTGGTTCTTGGGGAACTGCCCTTTCTCAGGTTCTTAATGACAATGGCCA
TGACGTCCGTTTATGGGGAAATATTCCTGATCAAATTGAAGAGATAAATACCAAGCATACCAATAGACACTACTTCAAAG
ACATTGTGTTAGACAAAAACATTACGGCAACTCTTGATTTAGGTCAAGCCCTATCAGATGTTGATGCGGTGCTTTTTGTT
GTGCCAACTAAAGTAACACGATTAGTTGCTAGACAAGTTGCCGCCATTTTAGATCATAAAGTAGTGGTCATGCATGCCTC
AAAAGGTCTAGAACCAGAGACCCACGAACGTTTATCAACTATCCTAGAAGAAGAAATTCCAGCTCATTTTCGTAGTGAAG
TGGTCGTTGTATCAGGTCCTAGTCATGCTGAAGAAACTATCGTTCGCGATATTACTCTCATCACGGCAGCCTCAAAAGAT
ATTGAAGCTGCAAAGTATGTTCAGTCCCTCTTTAGTAACCACTACTTCCGACTTTATACCAATACCGACGTCATCGGAGT
TGAAACAGCTGGTGCCCTCAAAAACATTATTGCTGTTGGAGCAGGAGCTCTCCATGGACTTGGGTATGGAGATAATGCCA
AAGCAGCGGTAATTACTCGTGGGTTAGCTGAAATCACCCGTCTAGGCGTCAAGCTTGGTGCTGACCCGTTAACCTACAGT
GGGTTATCTGGTGTTGGTGATCTAATTGTAACAGGTACTTCTGTCCATTCACGTAACTGGCGGGCTGGAGCTGCCTTGGA
CGTGGTGAAAAATTAG

Upstream 100 bases:

>100_bases
TGGGAACGCCTTATTAGCCAAGACCATATACCTTTTCTAATAGAGCTAATCAAGGTGTTATGTTATAATAGAGTGACTAG
CTCTTGAAGGAGAATTTAGA

Downstream 100 bases:

>100_bases
AAGATATTGAACGCAACATGGGTATGGTTATCGAAGGTATCGCAACAACTAAGGTAGCCTATGAAATTGCCCAAGACCTC
GGAGTTTACATGCCAATTAC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFV
VPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYS
GLSGVGDLIVTGTSVHSRNWRAGAALDVVKN

Sequences:

>Translated_271_residues
MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFV
VPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYS
GLSGVGDLIVTGTSVHSRNWRAGAALDVVKN
>Mature_270_residues
TKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVV
PTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKDI
EAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYSG
LSGVGDLIVTGTSVHSRNWRAGAALDVVKN

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=285, Percent_Identity=31.2280701754386, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI24307999, Length=279, Percent_Identity=30.8243727598566, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI1790037, Length=266, Percent_Identity=40.6015037593985, Blast_Score=190, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI32564399, Length=284, Percent_Identity=30.2816901408451, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI193210136, Length=292, Percent_Identity=29.7945205479452, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32564403, Length=277, Percent_Identity=30.3249097472924, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17507425, Length=276, Percent_Identity=27.1739130434783, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193210134, Length=275, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320181, Length=274, Percent_Identity=31.021897810219, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324513, Length=277, Percent_Identity=28.8808664259928, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136202, Length=282, Percent_Identity=30.1418439716312, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI17136200, Length=282, Percent_Identity=30.1418439716312, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17136204, Length=282, Percent_Identity=30.1418439716312, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45551945, Length=242, Percent_Identity=28.099173553719, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281362270, Length=242, Percent_Identity=28.099173553719, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI22026922, Length=284, Percent_Identity=23.5915492957746, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648969, Length=230, Percent_Identity=27.3913043478261, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 29110; Mature: 28978

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKN
CCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHEECCC
ITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLST
CEEEEHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
ILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKDIEAAKYVQSLFSNHYFRLYT
HHHHHCCHHHHCCEEEEECCCCHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCEEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
GLSGVGDLIVTGTSVHSRNWRAGAALDVVKN
CCCCCCCEEEECCCCCCCCCCCCCEEHCCCC
>Mature Secondary Structure 
TKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKN
CCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHEECCC
ITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLST
CEEEEHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
ILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKDIEAAKYVQSLFSNHYFRLYT
HHHHHCCHHHHCCEEEEECCCCHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCEEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
GLSGVGDLIVTGTSVHSRNWRAGAALDVVKN
CCCCCCCEEEECCCCCCCCCCCCCEEHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA