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The map label for this gene is gcp

Identifier: 71893984

GI number: 71893984

Start: 836729

End: 837697

Strand: Reverse

Name: gcp

Synonym: MHJ_0636

Alternate gene names: 71893984

Gene position: 837697-836729 (Counterclockwise)

Preceding gene: 71893985

Following gene: 71893979

Centisome position: 93.35

GC content: 31.06

Gene sequence:

>969_bases
ATGAAAATTTTAGGAATCGAAACTTCACATGATGATGCATCAGTTGCACTTTTTAGCGAAAATAAAGTGGAAATTTTGTT
AACAATTAGTCAATTTGAACTCCATGAACAATTTGGAGGAACAGTTCCTGAGCTTGCATCGCGAGAGCATTCGCGCAATT
TAGCAATAATTTTAGAGAAATTATTAGGAAAAAATATCGATTTTTCCACTATTGATGCAATTGCATATACAAAAAATCCG
GGATTGATAGGGCCTTTAAAAATTGGGTTTTTATTTGCCAGCGCGCTCTCGCTTTTTTTTAATAAGCCGTTAATTCCAAT
TGATCATCTTTTAGGGCATTTTTGGTCGGCTGCAATCGAAAACGACTTAGAATTCCCGGTATTATCCTTGTTGATTTCAG
GGGGTCATACTCAATTAATTTTTGCTGAAAACAAAAATAATTTAGAAATTATTGGTTCGACAGTTGATGATGCTCTTGGT
GAAATTTATGATAAAATTGGCCGAAGTTTGGGTTGTGGTTACCCCGGAGGACCTAAAATTGACTTAATTTGGCAACAAAA
TAATGTAAGAAATATGGAACTAATTGACTTTAGCCTGCCAAAAGTACTTGAAAATCCGTTAGATTTTTCTTTTAGCGGCC
TTAAAACCCAAGTAATAAATTATACTAATAATTTAAAGGAAAATTATTTATTTTCGCAAAAAAAAGTTGTTGAAATTGCT
GTTTCTTTTCAAAAAACAGTTATAAAATATTTAAAAAGGCAGCTTGATTTAGCACTTAAAACTAAAAAAAATGTAAAAAC
AATAACATTAGTAGGTGGGGTCGCGGCAAATTCAGAAATTCGGAAATTAATTAAAACATATGAAAATAAATATAAAGTGG
TTATTCCAAAAAAAGAATTCTGTACTGATAATGGGGCAATGATAGCAAAAGCAGCTCAAATTTTTCTTAAATTTAATGAA
GAAAAATAA

Upstream 100 bases:

>100_bases
CTCTTGAGTACTGACCCATATTATATATTTTAAGTTTTATATTATAATTATAACATAACATAGAAAAAATAAAAATAAAA
AATTAAAAAAAGTAGGTAAA

Downstream 100 bases:

>100_bases
ATAAAATTAAAGAAAATATAACTAAAGTCCAAAAAAATAAAGCATACTTAAAAAAATTAGTATTCTGCTTTTTAAGTTCA
AGATTTAGAATTGAATTATT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKILGIETSHDDASVALFSENKVEILLTISQFELHEQFGGTVPELASREHSRNLAIILEKLLGKNIDFSTIDAIAYTKNP
GLIGPLKIGFLFASALSLFFNKPLIPIDHLLGHFWSAAIENDLEFPVLSLLISGGHTQLIFAENKNNLEIIGSTVDDALG
EIYDKIGRSLGCGYPGGPKIDLIWQQNNVRNMELIDFSLPKVLENPLDFSFSGLKTQVINYTNNLKENYLFSQKKVVEIA
VSFQKTVIKYLKRQLDLALKTKKNVKTITLVGGVAANSEIRKLIKTYENKYKVVIPKKEFCTDNGAMIAKAAQIFLKFNE
EK

Sequences:

>Translated_322_residues
MKILGIETSHDDASVALFSENKVEILLTISQFELHEQFGGTVPELASREHSRNLAIILEKLLGKNIDFSTIDAIAYTKNP
GLIGPLKIGFLFASALSLFFNKPLIPIDHLLGHFWSAAIENDLEFPVLSLLISGGHTQLIFAENKNNLEIIGSTVDDALG
EIYDKIGRSLGCGYPGGPKIDLIWQQNNVRNMELIDFSLPKVLENPLDFSFSGLKTQVINYTNNLKENYLFSQKKVVEIA
VSFQKTVIKYLKRQLDLALKTKKNVKTITLVGGVAANSEIRKLIKTYENKYKVVIPKKEFCTDNGAMIAKAAQIFLKFNE
EK
>Mature_322_residues
MKILGIETSHDDASVALFSENKVEILLTISQFELHEQFGGTVPELASREHSRNLAIILEKLLGKNIDFSTIDAIAYTKNP
GLIGPLKIGFLFASALSLFFNKPLIPIDHLLGHFWSAAIENDLEFPVLSLLISGGHTQLIFAENKNNLEIIGSTVDDALG
EIYDKIGRSLGCGYPGGPKIDLIWQQNNVRNMELIDFSLPKVLENPLDFSFSGLKTQVINYTNNLKENYLFSQKKVVEIA
VSFQKTVIKYLKRQLDLALKTKKNVKTITLVGGVAANSEIRKLIKTYENKYKVVIPKKEFCTDNGAMIAKAAQIFLKFNE
EK

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=329, Percent_Identity=32.8267477203647, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI8923380, Length=317, Percent_Identity=28.391167192429, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1789445, Length=326, Percent_Identity=37.7300613496933, Blast_Score=210, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI17557464, Length=332, Percent_Identity=29.8192771084337, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71995670, Length=324, Percent_Identity=27.7777777777778, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320099, Length=340, Percent_Identity=29.7058823529412, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6322891, Length=318, Percent_Identity=27.3584905660377, Blast_Score=89, Evalue=7e-19,
Organism=Drosophila melanogaster, GI20129063, Length=333, Percent_Identity=29.7297297297297, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21357207, Length=328, Percent_Identity=27.4390243902439, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_MYCH2 (Q5ZZQ1)

Other databases:

- EMBL:   AE017332
- RefSeq:   YP_116164.1
- ProteinModelPortal:   Q5ZZQ1
- SMR:   Q5ZZQ1
- STRING:   Q5ZZQ1
- GeneID:   3105195
- GenomeReviews:   AE017332_GR
- KEGG:   mhy:mhp656
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   MHYO295358:MHP656-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 35961; Mature: 35961

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILGIETSHDDASVALFSENKVEILLTISQFELHEQFGGTVPELASREHSRNLAIILEK
CEEEEECCCCCCCEEEEEECCCEEEEEEEHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHH
LLGKNIDFSTIDAIAYTKNPGLIGPLKIGFLFASALSLFFNKPLIPIDHLLGHFWSAAIE
HHCCCCCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
NDLEFPVLSLLISGGHTQLIFAENKNNLEIIGSTVDDALGEIYDKIGRSLGCGYPGGPKI
CCCCHHHHHHHHCCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEE
DLIWQQNNVRNMELIDFSLPKVLENPLDFSFSGLKTQVINYTNNLKENYLFSQKKVVEIA
EEEECCCCCCCEEEEECCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSFQKTVIKYLKRQLDLALKTKKNVKTITLVGGVAANSEIRKLIKTYENKYKVVIPKKEF
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCHHH
CTDNGAMIAKAAQIFLKFNEEK
CCCCCHHHHHHHHHHEEECCCC
>Mature Secondary Structure
MKILGIETSHDDASVALFSENKVEILLTISQFELHEQFGGTVPELASREHSRNLAIILEK
CEEEEECCCCCCCEEEEEECCCEEEEEEEHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHH
LLGKNIDFSTIDAIAYTKNPGLIGPLKIGFLFASALSLFFNKPLIPIDHLLGHFWSAAIE
HHCCCCCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
NDLEFPVLSLLISGGHTQLIFAENKNNLEIIGSTVDDALGEIYDKIGRSLGCGYPGGPKI
CCCCHHHHHHHHCCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCEE
DLIWQQNNVRNMELIDFSLPKVLENPLDFSFSGLKTQVINYTNNLKENYLFSQKKVVEIA
EEEECCCCCCCEEEEECCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSFQKTVIKYLKRQLDLALKTKKNVKTITLVGGVAANSEIRKLIKTYENKYKVVIPKKEF
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCHHH
CTDNGAMIAKAAQIFLKFNEEK
CCCCCHHHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA