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The map label for this gene is dnaX [H]

Identifier: 71892083

GI number: 71892083

Start: 364540

End: 366636

Strand: Direct

Name: dnaX [H]

Synonym: BPEN_309

Alternate gene names: 71892083

Gene position: 364540-366636 (Clockwise)

Preceding gene: 71892082

Following gene: 71892084

Centisome position: 46.05

GC content: 27.94

Gene sequence:

>2097_bases
ATGAGTTATCAAGTACTCGCCCGTAAGTGGCGACCAAAAAAATTTTCTGATATTGTAGGGCAAGAACACATCATTCAAGC
AATAACACATACTTTTTCATTAAATAAAATTCACCACGCTTATATATTATCTGGTACAAGAGGAGTAGGAAAAACTACTA
TTGCTCGATTATTCGCAAAAGGATTAAACTGTGAACAAGGAACAACATATACCATGTGTGGTCAATGTAATAATTGCAAA
GATATTGAATTAGGTTGTTTTATTGATCTGATTGAAATAGACGCAGCATCACGCACTAAAGTAGAAGATACTAGGGAATT
TCTAGATAATGTACAATACATGCCATCTCGAGGTCGCTTTAAAGTATATCTTATAGATGAAGTACATATGTTATCCCGTC
ACAGTTTCAATGCTTTATTAAAGACGTTAGAAGAACCACCTACACATGTTAAATTTATTTTGGTTACTACTGAATACCAA
AAATTACCGGAGACTATCTTATCCCGGTGTTTACAGTTTTACTTGAAACCTCTAAACATTTCTCAAATTATAAATCAACT
AACATATATCTTTCATAAAGAAAACATAAACATAGAAACTTCTGCTTTAGAATCGTTAGCATATGCATCAAAAGGAAGTA
TGCGTGATGCGCTTAGTTTGGCAGAACAAGCTATTGTCTTAGGAAATAATGAGATAACTAATAATGTTATTAATAATATG
TTTGGTATATCGAATATCGAACATCCATTATGTTTAATCGAGAGCTTAATTGATGAAGATATACATAATATTATGCACCA
AATTGAAAATTTGACTGTTTTAGGAGTTCATTGGGATTATGTTTTCAATGAAATTCTTACTATCTTGCAGAAAATAGCTA
TAGGTCAATTTCTGTCAAATTCTGTACAAAAAGAGGATAACAATGTAACACAACATATCAATCAACGTATGCGTAGATTA
AGTAATCGTATTACTCCGGAAAATGTACAATTATATTATCAGATATTTCTATTAGGTCGTCGCGAATTGCCTTACGCTCC
TAGTCATCGCATGGGAATAGAAATGACCATGTTACGAGCATTAGCTTTTCGTCCTGATGTAGACATAGCAAACAAAAAAA
ATGGTAATGGTGATGATAATGATCATATACTTAAAAAATCTGTATGCTCAAATAATAATGTCGAGATAAATACTAATGAT
ACACAACATATTGCTACTGATCTTTTCCAAAAAAAAAATCATAATCAAGGTAGTAAGAATGTATTAAATACAGAAAAATT
AAAAAAAACAAATAATATATTACTTTTAAATTTTAAAAAATCCGAATTAAATTCGGATAATACCAAACCTAAAATTTCAA
AATCTGTCTCTAGTAGAGATACTAGGGATATTACTTCTACAATATTAGAAGCTCGATCAAAGCTATTACAATATAAAGAA
CGTGACAAGTTAAATGTCATAGAAAAAAAATCAAATTTAACTTTAGAATCTCAAAAAAAAATAAAAGATATATTAGAACG
ATTTGCCAGTATTAATACAATAATTTTAAAAAATAGTTCTGATCGTTTCGAAAAAATTAATAAAGATTTATCAGGATATT
TAGAATTTAGTAATAACAGTAATAATAAAGAAAATTTACATAGAAACCATCAAAATATGCCCGATTTCATAAAAGAAATA
CTTCAAAAAGCAATAAACAATAATTTATGGATATCACAAATATATCGTTTGTCGTTACCAAAATTAGCAAAAAAATTAGT
TATGAATTCGTGGAAAGAAAAAATTTCTTCAGATGAGATATGCTTACATGTTCGTTCTGATTACCAACATTTAAATTCTA
CAGAACTCCGTAATATCATACAAAAATCACTTAGCAATAATATAGGTATAGCAATAAAATTACATATAAAAAAAGATGAC
AATTATGCAATAAAAACACCAATGGAACATTTATATACTTTATATAAAGAAAAAATATCATTAATAAAGAAAGAATTTTC
AAGTGATCCGTACGTTAAAATGATTAAATCTTTTTTTGATGCTGAAATAGATGAAAATGATATTCAAGTACTTTATGATC
AGAATAAAAACTTATAA

Upstream 100 bases:

>100_bases
TATAGTTTAGTGACGTTCTCTAATCATTAAAATATACCCCACTAAACCAATAAGTTTTAGTTCTTATATTTATAATAATT
ACTATATGAGTTATATTCTG

Downstream 100 bases:

>100_bases
AAATTAATTAAATAAAATACACTATCTCTCAATTACATCGAAATTATAATGTAATATAGCAAATTAATATCAATTGCATA
TTTTTAAAAAATGTAATTTT

Product: DNA polymerase III, tau and gamma subunits

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 697

Protein sequence:

>698_residues
MSYQVLARKWRPKKFSDIVGQEHIIQAITHTFSLNKIHHAYILSGTRGVGKTTIARLFAKGLNCEQGTTYTMCGQCNNCK
DIELGCFIDLIEIDAASRTKVEDTREFLDNVQYMPSRGRFKVYLIDEVHMLSRHSFNALLKTLEEPPTHVKFILVTTEYQ
KLPETILSRCLQFYLKPLNISQIINQLTYIFHKENINIETSALESLAYASKGSMRDALSLAEQAIVLGNNEITNNVINNM
FGISNIEHPLCLIESLIDEDIHNIMHQIENLTVLGVHWDYVFNEILTILQKIAIGQFLSNSVQKEDNNVTQHINQRMRRL
SNRITPENVQLYYQIFLLGRRELPYAPSHRMGIEMTMLRALAFRPDVDIANKKNGNGDDNDHILKKSVCSNNNVEINTND
TQHIATDLFQKKNHNQGSKNVLNTEKLKKTNNILLLNFKKSELNSDNTKPKISKSVSSRDTRDITSTILEARSKLLQYKE
RDKLNVIEKKSNLTLESQKKIKDILERFASINTIILKNSSDRFEKINKDLSGYLEFSNNSNNKENLHRNHQNMPDFIKEI
LQKAINNNLWISQIYRLSLPKLAKKLVMNSWKEKISSDEICLHVRSDYQHLNSTELRNIIQKSLSNNIGIAIKLHIKKDD
NYAIKTPMEHLYTLYKEKISLIKKEFSSDPYVKMIKSFFDAEIDENDIQVLYDQNKNL

Sequences:

>Translated_698_residues
MSYQVLARKWRPKKFSDIVGQEHIIQAITHTFSLNKIHHAYILSGTRGVGKTTIARLFAKGLNCEQGTTYTMCGQCNNCK
DIELGCFIDLIEIDAASRTKVEDTREFLDNVQYMPSRGRFKVYLIDEVHMLSRHSFNALLKTLEEPPTHVKFILVTTEYQ
KLPETILSRCLQFYLKPLNISQIINQLTYIFHKENINIETSALESLAYASKGSMRDALSLAEQAIVLGNNEITNNVINNM
FGISNIEHPLCLIESLIDEDIHNIMHQIENLTVLGVHWDYVFNEILTILQKIAIGQFLSNSVQKEDNNVTQHINQRMRRL
SNRITPENVQLYYQIFLLGRRELPYAPSHRMGIEMTMLRALAFRPDVDIANKKNGNGDDNDHILKKSVCSNNNVEINTND
TQHIATDLFQKKNHNQGSKNVLNTEKLKKTNNILLLNFKKSELNSDNTKPKISKSVSSRDTRDITSTILEARSKLLQYKE
RDKLNVIEKKSNLTLESQKKIKDILERFASINTIILKNSSDRFEKINKDLSGYLEFSNNSNNKENLHRNHQNMPDFIKEI
LQKAINNNLWISQIYRLSLPKLAKKLVMNSWKEKISSDEICLHVRSDYQHLNSTELRNIIQKSLSNNIGIAIKLHIKKDD
NYAIKTPMEHLYTLYKEKISLIKKEFSSDPYVKMIKSFFDAEIDENDIQVLYDQNKNL
>Mature_697_residues
SYQVLARKWRPKKFSDIVGQEHIIQAITHTFSLNKIHHAYILSGTRGVGKTTIARLFAKGLNCEQGTTYTMCGQCNNCKD
IELGCFIDLIEIDAASRTKVEDTREFLDNVQYMPSRGRFKVYLIDEVHMLSRHSFNALLKTLEEPPTHVKFILVTTEYQK
LPETILSRCLQFYLKPLNISQIINQLTYIFHKENINIETSALESLAYASKGSMRDALSLAEQAIVLGNNEITNNVINNMF
GISNIEHPLCLIESLIDEDIHNIMHQIENLTVLGVHWDYVFNEILTILQKIAIGQFLSNSVQKEDNNVTQHINQRMRRLS
NRITPENVQLYYQIFLLGRRELPYAPSHRMGIEMTMLRALAFRPDVDIANKKNGNGDDNDHILKKSVCSNNNVEINTNDT
QHIATDLFQKKNHNQGSKNVLNTEKLKKTNNILLLNFKKSELNSDNTKPKISKSVSSRDTRDITSTILEARSKLLQYKER
DKLNVIEKKSNLTLESQKKIKDILERFASINTIILKNSSDRFEKINKDLSGYLEFSNNSNNKENLHRNHQNMPDFIKEIL
QKAINNNLWISQIYRLSLPKLAKKLVMNSWKEKISSDEICLHVRSDYQHLNSTELRNIIQKSLSNNIGIAIKLHIKKDDN
YAIKTPMEHLYTLYKEKISLIKKEFSSDPYVKMIKSFFDAEIDENDIQVLYDQNKNL

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI194306571, Length=269, Percent_Identity=23.0483271375465, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI194306567, Length=269, Percent_Identity=23.0483271375465, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI6677723, Length=266, Percent_Identity=23.3082706766917, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4506491, Length=246, Percent_Identity=23.5772357723577, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI31881687, Length=246, Percent_Identity=23.5772357723577, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI31563534, Length=306, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=3e-12,
Organism=Escherichia coli, GI1786676, Length=689, Percent_Identity=41.0740203193033, Blast_Score=546, Evalue=1e-156,
Organism=Escherichia coli, GI1787341, Length=173, Percent_Identity=28.3236994219653, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17541988, Length=309, Percent_Identity=23.3009708737864, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71986063, Length=264, Percent_Identity=23.4848484848485, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324478, Length=259, Percent_Identity=23.5521235521236, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322528, Length=294, Percent_Identity=22.108843537415, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324039, Length=257, Percent_Identity=24.124513618677, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17647857, Length=298, Percent_Identity=25.8389261744966, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19921076, Length=218, Percent_Identity=26.1467889908257, Blast_Score=74, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 80720; Mature: 80589

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQVLARKWRPKKFSDIVGQEHIIQAITHTFSLNKIHHAYILSGTRGVGKTTIARLFAK
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
GLNCEQGTTYTMCGQCNNCKDIELGCFIDLIEIDAASRTKVEDTREFLDNVQYMPSRGRF
CCCCCCCCCEEECCCCCCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCE
KVYLIDEVHMLSRHSFNALLKTLEEPPTHVKFILVTTEYQKLPETILSRCLQFYLKPLNI
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCH
SQIINQLTYIFHKENINIETSALESLAYASKGSMRDALSLAEQAIVLGNNEITNNVINNM
HHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCHHHHHHHHHH
FGISNIEHPLCLIESLIDEDIHNIMHQIENLTVLGVHWDYVFNEILTILQKIAIGQFLSN
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
SVQKEDNNVTQHINQRMRRLSNRITPENVQLYYQIFLLGRRELPYAPSHRMGIEMTMLRA
HHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHEEHHCCCCCCCCCCCCCCHHHHHHHH
LAFRPDVDIANKKNGNGDDNDHILKKSVCSNNNVEINTNDTQHIATDLFQKKNHNQGSKN
HHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCC
VLNTEKLKKTNNILLLNFKKSELNSDNTKPKISKSVSSRDTRDITSTILEARSKLLQYKE
CCCHHHHHCCCCEEEEEEEHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RDKLNVIEKKSNLTLESQKKIKDILERFASINTIILKNSSDRFEKINKDLSGYLEFSNNS
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHEEEECCCC
NNKENLHRNHQNMPDFIKEILQKAINNNLWISQIYRLSLPKLAKKLVMNSWKEKISSDEI
CCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
CLHVRSDYQHLNSTELRNIIQKSLSNNIGIAIKLHIKKDDNYAIKTPMEHLYTLYKEKIS
EEEEHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEECCHHHHHHHHHHHHHH
LIKKEFSSDPYVKMIKSFFDAEIDENDIQVLYDQNKNL
HHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SYQVLARKWRPKKFSDIVGQEHIIQAITHTFSLNKIHHAYILSGTRGVGKTTIARLFAK
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
GLNCEQGTTYTMCGQCNNCKDIELGCFIDLIEIDAASRTKVEDTREFLDNVQYMPSRGRF
CCCCCCCCCEEECCCCCCCCCCCHHHEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCE
KVYLIDEVHMLSRHSFNALLKTLEEPPTHVKFILVTTEYQKLPETILSRCLQFYLKPLNI
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCH
SQIINQLTYIFHKENINIETSALESLAYASKGSMRDALSLAEQAIVLGNNEITNNVINNM
HHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCHHHHHHHHHH
FGISNIEHPLCLIESLIDEDIHNIMHQIENLTVLGVHWDYVFNEILTILQKIAIGQFLSN
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
SVQKEDNNVTQHINQRMRRLSNRITPENVQLYYQIFLLGRRELPYAPSHRMGIEMTMLRA
HHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHEEHHCCCCCCCCCCCCCCHHHHHHHH
LAFRPDVDIANKKNGNGDDNDHILKKSVCSNNNVEINTNDTQHIATDLFQKKNHNQGSKN
HHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCC
VLNTEKLKKTNNILLLNFKKSELNSDNTKPKISKSVSSRDTRDITSTILEARSKLLQYKE
CCCHHHHHCCCCEEEEEEEHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RDKLNVIEKKSNLTLESQKKIKDILERFASINTIILKNSSDRFEKINKDLSGYLEFSNNS
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHEEEECCCC
NNKENLHRNHQNMPDFIKEILQKAINNNLWISQIYRLSLPKLAKKLVMNSWKEKISSDEI
CCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
CLHVRSDYQHLNSTELRNIIQKSLSNNIGIAIKLHIKKDDNYAIKTPMEHLYTLYKEKIS
EEEEHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEECCHHHHHHHHHHHHHH
LIKKEFSSDPYVKMIKSFFDAEIDENDIQVLYDQNKNL
HHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]