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The map label for this gene is apt

Identifier: 71892082

GI number: 71892082

Start: 363915

End: 364469

Strand: Direct

Name: apt

Synonym: BPEN_308

Alternate gene names: 71892082

Gene position: 363915-364469 (Clockwise)

Preceding gene: 71892081

Following gene: 71892083

Centisome position: 45.97

GC content: 32.25

Gene sequence:

>555_bases
ATGACAAATGTTACGGATCAACAATTAGAATTGATCAAAAAAAGTATCCAATTTGTACCTAATTATCCAAAAAAAGGCAT
TTTATTTCGAGACATCACTGAATTGTTAAAAAATCCTCAAGCATATTCAGCAAGCATTACTCTTTTGGCCTATTATTATA
GAAATCATAAATTAACTAAAGTAGTAGGTATAGAAGCTAGAGGATTCTTATTCAGTGCTCCATTAGCACTAATACTGAAA
CTAGGTTTTATTCCAGCCCGTAAATCAGGAAGGTTACCCCGTGATACTATTAGAGAGCCATATATTTTAGAATATGATAA
TGGATTCTTAGAAATACACACCGATTCTATTACTCCAGGTGACCAAGTTTTAATCATAGATGATTTACTAGCAACGGGCG
GAACAATTGCAGCAGCGGTAAAATTAATCAGACGGTTAGGAGGAGAAGTAAATCATGCTGGATTTATAATAGATTTAGAA
AATCTAGGTGGAAAATCATTATTAAAGGAAATAGGAATAAATTCCTATAGTTTAGTGACGTTCTCTAATCATTAA

Upstream 100 bases:

>100_bases
TTTACGAATAAAATAATTTAATAAAATTTAGTGGCAAAATAAAATTTATGTATAAATGTATACAAATTCAAATAAATATT
GTTTTTATTTTGGAAAAAAT

Downstream 100 bases:

>100_bases
AATATACCCCACTAAACCAATAAGTTTTAGTTCTTATATTTATAATAATTACTATATGAGTTATATTCTGATGAGTTATC
AAGTACTCGCCCGTAAGTGG

Product: adenine phosphoribosyltransferase

Products: NA

Alternate protein names: APRT

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MTNVTDQQLELIKKSIQFVPNYPKKGILFRDITELLKNPQAYSASITLLAYYYRNHKLTKVVGIEARGFLFSAPLALILK
LGFIPARKSGRLPRDTIREPYILEYDNGFLEIHTDSITPGDQVLIIDDLLATGGTIAAAVKLIRRLGGEVNHAGFIIDLE
NLGGKSLLKEIGINSYSLVTFSNH

Sequences:

>Translated_184_residues
MTNVTDQQLELIKKSIQFVPNYPKKGILFRDITELLKNPQAYSASITLLAYYYRNHKLTKVVGIEARGFLFSAPLALILK
LGFIPARKSGRLPRDTIREPYILEYDNGFLEIHTDSITPGDQVLIIDDLLATGGTIAAAVKLIRRLGGEVNHAGFIIDLE
NLGGKSLLKEIGINSYSLVTFSNH
>Mature_183_residues
TNVTDQQLELIKKSIQFVPNYPKKGILFRDITELLKNPQAYSASITLLAYYYRNHKLTKVVGIEARGFLFSAPLALILKL
GFIPARKSGRLPRDTIREPYILEYDNGFLEIHTDSITPGDQVLIIDDLLATGGTIAAAVKLIRRLGGEVNHAGFIIDLEN
LGGKSLLKEIGINSYSLVTFSNH

Specific function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family

Homologues:

Organism=Homo sapiens, GI4502171, Length=171, Percent_Identity=39.1812865497076, Blast_Score=133, Evalue=7e-32,
Organism=Homo sapiens, GI71773201, Length=133, Percent_Identity=40.6015037593985, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI1786675, Length=182, Percent_Identity=62.0879120879121, Blast_Score=225, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17509087, Length=180, Percent_Identity=41.1111111111111, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323619, Length=161, Percent_Identity=36.6459627329193, Blast_Score=101, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6320649, Length=171, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17136334, Length=166, Percent_Identity=38.5542168674699, Blast_Score=114, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APT_BLOPB (Q493A5)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277812.1
- HSSP:   P07741
- ProteinModelPortal:   Q493A5
- SMR:   Q493A5
- STRING:   Q493A5
- GeneID:   3562585
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_308
- eggNOG:   COG0503
- HOGENOM:   HBG703830
- OMA:   GILFYDI
- ProtClustDB:   PRK02304
- BioCyc:   CBLO291272:BPEN_308-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00004
- InterPro:   IPR005764
- InterPro:   IPR000836
- TIGRFAMs:   TIGR01090

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.7

Molecular weight: Translated: 20457; Mature: 20326

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER; PS00144 ASN_GLN_ASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVTDQQLELIKKSIQFVPNYPKKGILFRDITELLKNPQAYSASITLLAYYYRNHKLTK
CCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHHHHEEEEEHHCCCEEE
VVGIEARGFLFSAPLALILKLGFIPARKSGRLPRDTIREPYILEYDNGFLEIHTDSITPG
EEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEECCCEEEEEECCCCCC
DQVLIIDDLLATGGTIAAAVKLIRRLGGEVNHAGFIIDLENLGGKSLLKEIGINSYSLVT
CEEEEEEHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEE
FSNH
EECC
>Mature Secondary Structure 
TNVTDQQLELIKKSIQFVPNYPKKGILFRDITELLKNPQAYSASITLLAYYYRNHKLTK
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHHHHEEEEEHHCCCEEE
VVGIEARGFLFSAPLALILKLGFIPARKSGRLPRDTIREPYILEYDNGFLEIHTDSITPG
EEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEECCCEEEEEECCCCCC
DQVLIIDDLLATGGTIAAAVKLIRRLGGEVNHAGFIIDLENLGGKSLLKEIGINSYSLVT
CEEEEEEHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEE
FSNH
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA