| Definition | Candidatus Blochmannia pennsylvanicus str. BPEN, complete genome. |
|---|---|
| Accession | NC_007292 |
| Length | 791,654 |
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The map label for this gene is lon [H]
Identifier: 71892081
GI number: 71892081
Start: 359892
End: 362255
Strand: Direct
Name: lon [H]
Synonym: BPEN_307
Alternate gene names: 71892081
Gene position: 359892-362255 (Clockwise)
Preceding gene: 71892080
Following gene: 71892082
Centisome position: 45.46
GC content: 34.64
Gene sequence:
>2364_bases ATGAATACTGATCAAACTGAGCGCATAGAAATACCTGTGTTACCTTTGCGTGATGTAGTGGTGTATCCACATATGGTGAT TCCGTTATTCGTTGGTCGGGAAAAATCAATTAAATGTCTCGAATCTGCCATGAATGGCGACAAAAAAGTTATGTTAGTAG CTCAAAAAGAAGCATCAACCGATGAACCAAGTATTAATGACCTTTTTTCGGTTGGAACAATATCTATAATATTACAGATG CTTAAATTACCAGATGGTACAGTCAAAGTATTAGTAGAAGGAATAGAGCGTGCCCGTATCATTGAGTTAACTGATACTGG AAATCATTTTAAAGCTCAAGCAAGTGTTTTTCATTCTAATGAATTAAACGAACGTGAACAAGAAATTCTAATGCGCACTG TTATTAATCAATTTGAAGGATTTCTTAAACTTAATAAGAAAATACCTTCTGAAGTTTTAACATCCTTGAATAATATTGAC AAGGCAGATCGTCTTGCTGATACCATCGCCGCGCATATGCCACTCAAATTAGATGATAAACAATCCATTTTAGAAATGTC AGATGTTACGGAAAGATTAGAATATTTAATAGCAATGATGGAATCAGAAATTGAATTATTACAAGTTGAAAAACGTATTC GTAATCGCGTAAAAAAACAAATGGAAAAAAGCCAACGTGAGTATTACTTAAATGAACAAATGAAAGCTATACAAAAAGAA CTGGGAGAACTAGATGCTGTTATTGACGAAAACGAATCTCTTAGACGTAAAATAGAAGCAGCTAAAATGCCTAAAGAGGC ACGAAACAAAGTAGAATCAGAGTGGCAAAAATTGAAAATGATGTCCCCTATGTCTGCTGAAGCTGCTGTAGTTCGCGGAT ATATTGATTGGATACTGTCAGTACCTTGGCATGCAAGAAGTAAAATGAAAAAAGATTTGCTTAAAGCTCAAGAAAGCCTG GACAAAGATCACTACGGATTAGAGCGTGTTAAAGATCGAATTTTAGAATATTTAGCAGTACAAAACAGAATCAATAAAAT TAAAGGACCTATTTTATGTTTAGTAGGACCGCCCGGAGTAGGTAAAACATCACTTGGGCGATCTATTGCTAAAGCAACTG GACGTAAGTATATACGTATGGCTTTAGGTGGTATGCGCGATGAAGCCGAAATTAGAGGCCACCGTCGCACCTACATTGGA TCTATGCCTGGTAAACTTATACAAAAGATGTCTAAAGTTGGAGTAAGGAATCCGTTATTCCTTTTAGATGAAATAGATAA AATGTCTTTAGATATGCGTGGAGATCCAGCGGCTGCTTTACTAGAAGTATTAGATCCCGAGCAAAATACTACTTTTAATG ATCATTATTTAGAAATAGATTATGATTTATCTGATGTTATGTTTGTTGCTACTTCTAACTCAATGGATATTCCCAGTCCT TTGTTAGATCGTATGGAAGTAATACGTCTATCTGGTTATACCGAAGATGAAAAGTTAAATATAGCACGACAACATTTATT CACTAAACAAATAGAGCGCAACGCTTTAAAGATAGAAGAACTAACAATTCAAGACGATGCTTTAGTAAATATTATTAGAC ATTATACACGCGAAGCTGGAGTACGTAATTTAGAACGAGAAATTTCTAAATTATGTCGTAAAACAGTAAAAATGCTTTTA ATGAATAAAAAAATAAGACATATAACCATTGATAAAAATAATTTAAAAGACTTTCTTGGTGTGCAACGCTATGATTGTAT TCATGCAGATCAAGAAAATCGTGTAGGGCAAGTTACTGGATTAGCTTGGACTGAAGTAGGAGGAGATCTTTTAACTATTG AAACTGCTTGTGTTCCGGGAAAAGGAAAATTAACATATACTGGATCTTTAGGTGAAGTTATGCAAGAATCTATTCAAGCC GCATTAACTGTGGTAAGAGCGCGTGCGGATAAATTAGGTATTAATACTGATTTTTATGAAAAAAAAGACATTCATGTACA TGTTCCAGAAGGAGCTACGCCAAAAGACGGACCAAGTGCTGGAATTGCTATGTGTACTGCTTTAGTTTCTTGCTTAACAG GAAATTCTGTTAAAGCTAGTGTAGCGATGACAGGAGAAATAACTTTAAGGGGACAAATATTACCTATTGGTGGATTGAAA GAAAAATTGTTAGCTGCGCATCGAGGAGGTATTAAAACAGTATTAATACCGTATGAAAACAAACGTGACTTAGAAGATAT GCCAGCTATTGTAGTTAATAATTTGGATATTCATCCAGTCAAACAAATAGACGAAGTTTTAATATTAGCGCTACAAGATA TCCCGTTTAATTCTGAAATAATACCTAAAGCACCATTAGTATGA
Upstream 100 bases:
>100_bases ATTTATCCCCATATTTTTAGGTATTTGATTATTAAAATGGTGCAGCCGAATATTAAAAATGTTATAATATTAATAAGTTA TAACCAAGAGAGATCGCTCT
Downstream 100 bases:
>100_bases TGTATCGTGTAATTTTTAGAAACATAGAGATATATTAAAAATAAGGTGTATCATTTATTGTATTAAAATAATCACATATG AATGTATGTGAGAACTATAG
Product: DNA-binding ATP-dependent protease La
Products: NA
Alternate protein names: ATP-dependent protease La [H]
Number of amino acids: Translated: 787; Mature: 787
Protein sequence:
>787_residues MNTDQTERIEIPVLPLRDVVVYPHMVIPLFVGREKSIKCLESAMNGDKKVMLVAQKEASTDEPSINDLFSVGTISIILQM LKLPDGTVKVLVEGIERARIIELTDTGNHFKAQASVFHSNELNEREQEILMRTVINQFEGFLKLNKKIPSEVLTSLNNID KADRLADTIAAHMPLKLDDKQSILEMSDVTERLEYLIAMMESEIELLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKE LGELDAVIDENESLRRKIEAAKMPKEARNKVESEWQKLKMMSPMSAEAAVVRGYIDWILSVPWHARSKMKKDLLKAQESL DKDHYGLERVKDRILEYLAVQNRINKIKGPILCLVGPPGVGKTSLGRSIAKATGRKYIRMALGGMRDEAEIRGHRRTYIG SMPGKLIQKMSKVGVRNPLFLLDEIDKMSLDMRGDPAAALLEVLDPEQNTTFNDHYLEIDYDLSDVMFVATSNSMDIPSP LLDRMEVIRLSGYTEDEKLNIARQHLFTKQIERNALKIEELTIQDDALVNIIRHYTREAGVRNLEREISKLCRKTVKMLL MNKKIRHITIDKNNLKDFLGVQRYDCIHADQENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQA ALTVVRARADKLGINTDFYEKKDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNSVKASVAMTGEITLRGQILPIGGLK EKLLAAHRGGIKTVLIPYENKRDLEDMPAIVVNNLDIHPVKQIDEVLILALQDIPFNSEIIPKAPLV
Sequences:
>Translated_787_residues MNTDQTERIEIPVLPLRDVVVYPHMVIPLFVGREKSIKCLESAMNGDKKVMLVAQKEASTDEPSINDLFSVGTISIILQM LKLPDGTVKVLVEGIERARIIELTDTGNHFKAQASVFHSNELNEREQEILMRTVINQFEGFLKLNKKIPSEVLTSLNNID KADRLADTIAAHMPLKLDDKQSILEMSDVTERLEYLIAMMESEIELLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKE LGELDAVIDENESLRRKIEAAKMPKEARNKVESEWQKLKMMSPMSAEAAVVRGYIDWILSVPWHARSKMKKDLLKAQESL DKDHYGLERVKDRILEYLAVQNRINKIKGPILCLVGPPGVGKTSLGRSIAKATGRKYIRMALGGMRDEAEIRGHRRTYIG SMPGKLIQKMSKVGVRNPLFLLDEIDKMSLDMRGDPAAALLEVLDPEQNTTFNDHYLEIDYDLSDVMFVATSNSMDIPSP LLDRMEVIRLSGYTEDEKLNIARQHLFTKQIERNALKIEELTIQDDALVNIIRHYTREAGVRNLEREISKLCRKTVKMLL MNKKIRHITIDKNNLKDFLGVQRYDCIHADQENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQA ALTVVRARADKLGINTDFYEKKDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNSVKASVAMTGEITLRGQILPIGGLK EKLLAAHRGGIKTVLIPYENKRDLEDMPAIVVNNLDIHPVKQIDEVLILALQDIPFNSEIIPKAPLV >Mature_787_residues MNTDQTERIEIPVLPLRDVVVYPHMVIPLFVGREKSIKCLESAMNGDKKVMLVAQKEASTDEPSINDLFSVGTISIILQM LKLPDGTVKVLVEGIERARIIELTDTGNHFKAQASVFHSNELNEREQEILMRTVINQFEGFLKLNKKIPSEVLTSLNNID KADRLADTIAAHMPLKLDDKQSILEMSDVTERLEYLIAMMESEIELLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKE LGELDAVIDENESLRRKIEAAKMPKEARNKVESEWQKLKMMSPMSAEAAVVRGYIDWILSVPWHARSKMKKDLLKAQESL DKDHYGLERVKDRILEYLAVQNRINKIKGPILCLVGPPGVGKTSLGRSIAKATGRKYIRMALGGMRDEAEIRGHRRTYIG SMPGKLIQKMSKVGVRNPLFLLDEIDKMSLDMRGDPAAALLEVLDPEQNTTFNDHYLEIDYDLSDVMFVATSNSMDIPSP LLDRMEVIRLSGYTEDEKLNIARQHLFTKQIERNALKIEELTIQDDALVNIIRHYTREAGVRNLEREISKLCRKTVKMLL MNKKIRHITIDKNNLKDFLGVQRYDCIHADQENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQA ALTVVRARADKLGINTDFYEKKDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNSVKASVAMTGEITLRGQILPIGGLK EKLLAAHRGGIKTVLIPYENKRDLEDMPAIVVNNLDIHPVKQIDEVLILALQDIPFNSEIIPKAPLV
Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced
COG id: COG0466
COG function: function code O; ATP-dependent Lon protease, bacterial type
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Lon domain [H]
Homologues:
Organism=Homo sapiens, GI21396489, Length=677, Percent_Identity=39.8818316100443, Blast_Score=506, Evalue=1e-143, Organism=Homo sapiens, GI31377667, Length=777, Percent_Identity=37.5804375804376, Blast_Score=501, Evalue=1e-141, Organism=Escherichia coli, GI1786643, Length=781, Percent_Identity=81.6901408450704, Blast_Score=1316, Evalue=0.0, Organism=Caenorhabditis elegans, GI17505831, Length=657, Percent_Identity=40.6392694063927, Blast_Score=489, Evalue=1e-138, Organism=Caenorhabditis elegans, GI17556486, Length=538, Percent_Identity=39.5910780669145, Blast_Score=410, Evalue=1e-114, Organism=Saccharomyces cerevisiae, GI6319449, Length=682, Percent_Identity=38.8563049853372, Blast_Score=476, Evalue=1e-135, Organism=Drosophila melanogaster, GI221513036, Length=626, Percent_Identity=44.408945686901, Blast_Score=528, Evalue=1e-150, Organism=Drosophila melanogaster, GI24666867, Length=626, Percent_Identity=44.408945686901, Blast_Score=527, Evalue=1e-150,
Paralogues:
None
Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR008269 - InterPro: IPR004815 - InterPro: IPR003111 - InterPro: IPR008268 - InterPro: IPR001984 - InterPro: IPR015947 - InterPro: IPR020568 [H]
Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]
EC number: =3.4.21.53 [H]
Molecular weight: Translated: 88673; Mature: 88673
Theoretical pI: Translated: 7.10; Mature: 7.10
Prosite motif: PS01046 LON_SER
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 5.0 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 4.1 %Met (Mature Protein) 5.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNTDQTERIEIPVLPLRDVVVYPHMVIPLFVGREKSIKCLESAMNGDKKVMLVAQKEAST CCCCCCCEEEECCCCHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCCC DEPSINDLFSVGTISIILQMLKLPDGTVKVLVEGIERARIIELTDTGNHFKAQASVFHSN CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHCC ELNEREQEILMRTVINQFEGFLKLNKKIPSEVLTSLNNIDKADRLADTIAAHMPLKLDDK CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCH QSILEMSDVTERLEYLIAMMESEIELLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LGELDAVIDENESLRRKIEAAKMPKEARNKVESEWQKLKMMSPMSAEAAVVRGYIDWILS HHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC VPWHARSKMKKDLLKAQESLDKDHYGLERVKDRILEYLAVQNRINKIKGPILCLVGPPGV CCHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC GKTSLGRSIAKATGRKYIRMALGGMRDEAEIRGHRRTYIGSMPGKLIQKMSKVGVRNPLF CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHCCCCCHHHHHHHHHCCCCCCCH LLDEIDKMSLDMRGDPAAALLEVLDPEQNTTFNDHYLEIDYDLSDVMFVATSNSMDIPSP HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCHH LLDRMEVIRLSGYTEDEKLNIARQHLFTKQIERNALKIEELTIQDDALVNIIRHYTREAG HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHHHHH VRNLEREISKLCRKTVKMLLMNKKIRHITIDKNNLKDFLGVQRYDCIHADQENRVGQVTG HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCHHHHCCCCCCCCCCEEEEC LAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARADKLGINTDFYE EEHHHCCCCEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC KKDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNSVKASVAMTGEITLRGQILPIGGLK CCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEEEECCCHH EKLLAAHRGGIKTVLIPYENKRDLEDMPAIVVNNLDIHPVKQIDEVLILALQDIPFNSEI HHHHHHHCCCCEEEEEECCCCCCHHHCCHHEECCCCCCCHHHHHHHHHHHHHCCCCCCCC IPKAPLV CCCCCCC >Mature Secondary Structure MNTDQTERIEIPVLPLRDVVVYPHMVIPLFVGREKSIKCLESAMNGDKKVMLVAQKEAST CCCCCCCEEEECCCCHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEECCCCC DEPSINDLFSVGTISIILQMLKLPDGTVKVLVEGIERARIIELTDTGNHFKAQASVFHSN CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHCC ELNEREQEILMRTVINQFEGFLKLNKKIPSEVLTSLNNIDKADRLADTIAAHMPLKLDDK CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCH QSILEMSDVTERLEYLIAMMESEIELLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LGELDAVIDENESLRRKIEAAKMPKEARNKVESEWQKLKMMSPMSAEAAVVRGYIDWILS HHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC VPWHARSKMKKDLLKAQESLDKDHYGLERVKDRILEYLAVQNRINKIKGPILCLVGPPGV CCHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC GKTSLGRSIAKATGRKYIRMALGGMRDEAEIRGHRRTYIGSMPGKLIQKMSKVGVRNPLF CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHCCCCCHHHHHHHHHCCCCCCCH LLDEIDKMSLDMRGDPAAALLEVLDPEQNTTFNDHYLEIDYDLSDVMFVATSNSMDIPSP HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCHH LLDRMEVIRLSGYTEDEKLNIARQHLFTKQIERNALKIEELTIQDDALVNIIRHYTREAG HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHHHHHHH VRNLEREISKLCRKTVKMLLMNKKIRHITIDKNNLKDFLGVQRYDCIHADQENRVGQVTG HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCHHHHCCCCCCCCCCEEEEC LAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQAALTVVRARADKLGINTDFYE EEHHHCCCCEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC KKDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNSVKASVAMTGEITLRGQILPIGGLK CCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEEEECCCHH EKLLAAHRGGIKTVLIPYENKRDLEDMPAIVVNNLDIHPVKQIDEVLILALQDIPFNSEI HHHHHHHCCCCEEEEEECCCCCCHHHCCHHEECCCCCCCHHHHHHHHHHHHHCCCCCCCC IPKAPLV CCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA