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The map label for this gene is pmbA [H]

Identifier: 71892080

GI number: 71892080

Start: 357217

End: 358557

Strand: Direct

Name: pmbA [H]

Synonym: BPEN_306

Alternate gene names: 71892080

Gene position: 357217-358557 (Clockwise)

Preceding gene: 71892079

Following gene: 71892081

Centisome position: 45.12

GC content: 32.44

Gene sequence:

>1341_bases
ATGAATGATATAGATGACGTGATACAACAACGTAATTTTTTAGAAAATATAGTACATCAAACATTAAATTTAGCACATAC
ATATTCAAATGAAGTGGCAGTTTCAGTAGTTAAAACCACAGGAATTACAGTCAGTACTCGTTACGGAAAACTTGAGAATG
TGGAATTTAATAATCGTAGTATCTTAGATATAACTATATTTCGTCAACAACGAAAAGGCAGCGCTCTTTCGAATGATTTA
AATAAGAAAGCAATAAATCGTACTGTAGCAGCTGCAGCAGATATAGCATCTTATACTTCTCCAGACCCATATGCTGGAAT
TGCCGATAAAGAACTATTAGCATTCAATTCTATGAATCTTGAATTATTTCATCCAATTAGTTTAGATACTAAATTAGGAG
TGACTTTAGCATCTACAGCAGAAGAAACAGCATTAAAATATGATAAACGTATAATTTATACTGAAGGAGGTAGATTTAGC
AGTTATTTTACCACTAAAGTTTTTGGGAATAGTCATGGTATGTTACAAAGTTACACCAGTAGCCGACATTCTTTATGTTG
TGGTGTGATTGCTGCAAGCAATGATATTATGGAACAAAATTATGCATATACATTAAGTCGTTCATTTGATGATTTACGTT
CAGCAGAATGGGTTGGACAAGAATGTGCTCAACGCGCTCTAAATCATTTAAATCCTAAAAAATTAAAAACAATGGAATCT
CCAGTATTATTCTCTGCAGAAGTAGCTACAAGTTTATTCCACCATTTAGCAAGTGCTATTCATGGGGATAATGTATTTCG
TAAATCTACTTTTTTATTAAATGATCTGAAGAAAAAAATTTTTCCTTCTTGGATATCAATCAAAGAACGCCCGCATGTAT
TAAAAGGATTAGGATCAGCTCCATTTGATAGCGAAGGAATACAAACTTTGAACCGCACTATTGTAGAAAATGGTATATTA
AATAGTTGGATTTTAAACAGTTATTCTGCACGTAAAATGGGGATAAAAAACACTGGACATGCTGACGGTATCTATAATTG
GTATATTAGTTATCAAAATTTAAGTTTTATGGAATTAATTAAGAATATGCAACGCGGCCTTGTTGTTACTAACATCATGG
GGCAAGGAATTAATATTACTACCGGAGATTACTCACGTGGAGTAGCTGGTTTTTGGGTAGAAAACGGTGATATTCAGTAT
CCAGTAAATGAAATTGCTATTGCTGGCAATCTAAAAGATATGTTTTATAACATTGATGCTATTGGACACGATATTGAAAC
ACGTAATCATATTCATTGTGGATCTGTTTTAATATCTTCTATGAAGATAGCAGGTATTTAA

Upstream 100 bases:

>100_bases
CATGCTGTATAGTTATTAACATCAGTTACTGATGTTAATAACTCTGATATGGATTAGAGACATTTATATTAATTAGGAAT
TTTTATTACAGGAGGATAGT

Downstream 100 bases:

>100_bases
AATAATAATTATACATATACAGATATACATAATTAATAAAATTATTGTATCTATTGCATGATTTTTGTAGTTTTACAGCG
TAAAGAATAACTCTTTAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MNDIDDVIQQRNFLENIVHQTLNLAHTYSNEVAVSVVKTTGITVSTRYGKLENVEFNNRSILDITIFRQQRKGSALSNDL
NKKAINRTVAAAADIASYTSPDPYAGIADKELLAFNSMNLELFHPISLDTKLGVTLASTAEETALKYDKRIIYTEGGRFS
SYFTTKVFGNSHGMLQSYTSSRHSLCCGVIAASNDIMEQNYAYTLSRSFDDLRSAEWVGQECAQRALNHLNPKKLKTMES
PVLFSAEVATSLFHHLASAIHGDNVFRKSTFLLNDLKKKIFPSWISIKERPHVLKGLGSAPFDSEGIQTLNRTIVENGIL
NSWILNSYSARKMGIKNTGHADGIYNWYISYQNLSFMELIKNMQRGLVVTNIMGQGINITTGDYSRGVAGFWVENGDIQY
PVNEIAIAGNLKDMFYNIDAIGHDIETRNHIHCGSVLISSMKIAGI

Sequences:

>Translated_446_residues
MNDIDDVIQQRNFLENIVHQTLNLAHTYSNEVAVSVVKTTGITVSTRYGKLENVEFNNRSILDITIFRQQRKGSALSNDL
NKKAINRTVAAAADIASYTSPDPYAGIADKELLAFNSMNLELFHPISLDTKLGVTLASTAEETALKYDKRIIYTEGGRFS
SYFTTKVFGNSHGMLQSYTSSRHSLCCGVIAASNDIMEQNYAYTLSRSFDDLRSAEWVGQECAQRALNHLNPKKLKTMES
PVLFSAEVATSLFHHLASAIHGDNVFRKSTFLLNDLKKKIFPSWISIKERPHVLKGLGSAPFDSEGIQTLNRTIVENGIL
NSWILNSYSARKMGIKNTGHADGIYNWYISYQNLSFMELIKNMQRGLVVTNIMGQGINITTGDYSRGVAGFWVENGDIQY
PVNEIAIAGNLKDMFYNIDAIGHDIETRNHIHCGSVLISSMKIAGI
>Mature_446_residues
MNDIDDVIQQRNFLENIVHQTLNLAHTYSNEVAVSVVKTTGITVSTRYGKLENVEFNNRSILDITIFRQQRKGSALSNDL
NKKAINRTVAAAADIASYTSPDPYAGIADKELLAFNSMNLELFHPISLDTKLGVTLASTAEETALKYDKRIIYTEGGRFS
SYFTTKVFGNSHGMLQSYTSSRHSLCCGVIAASNDIMEQNYAYTLSRSFDDLRSAEWVGQECAQRALNHLNPKKLKTMES
PVLFSAEVATSLFHHLASAIHGDNVFRKSTFLLNDLKKKIFPSWISIKERPHVLKGLGSAPFDSEGIQTLNRTIVENGIL
NSWILNSYSARKMGIKNTGHADGIYNWYISYQNLSFMELIKNMQRGLVVTNIMGQGINITTGDYSRGVAGFWVENGDIQY
PVNEIAIAGNLKDMFYNIDAIGHDIETRNHIHCGSVLISSMKIAGI

Specific function: May facilitate the secretion of the peptide antibiotic microcin B17 (MccB17) by completing its maturation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1790682, Length=445, Percent_Identity=59.5505617977528, Blast_Score=564, Evalue=1e-162,
Organism=Escherichia coli, GI1789640, Length=247, Percent_Identity=21.8623481781377, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49674; Mature: 49674

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDIDDVIQQRNFLENIVHQTLNLAHTYSNEVAVSVVKTTGITVSTRYGKLENVEFNNRS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEECCCCEECEECCCCE
ILDITIFRQQRKGSALSNDLNKKAINRTVAAAADIASYTSPDPYAGIADKELLAFNSMNL
EEEEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCE
ELFHPISLDTKLGVTLASTAEETALKYDKRIIYTEGGRFSSYFTTKVFGNSHGMLQSYTS
EEEECCCCCCCCCEEEECCHHHHHHHHCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHC
SRHSLCCGVIAASNDIMEQNYAYTLSRSFDDLRSAEWVGQECAQRALNHLNPKKLKTMES
CCCCEEEEEEECCCHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
PVLFSAEVATSLFHHLASAIHGDNVFRKSTFLLNDLKKKIFPSWISIKERPHVLKGLGSA
CCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHCCCC
PFDSEGIQTLNRTIVENGILNSWILNSYSARKMGIKNTGHADGIYNWYISYQNLSFMELI
CCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHCCCCCCCCCCCEEEEEEEECCCHHHHHH
KNMQRGLVVTNIMGQGINITTGDYSRGVAGFWVENGDIQYPVNEIAIAGNLKDMFYNIDA
HHHHCCEEEEEECCCCCEEECCCCCCCCEEEEEECCCEECCHHHEEEECCHHHHHEEHHH
IGHDIETRNHIHCGSVLISSMKIAGI
HCCCCCCCCCEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDIDDVIQQRNFLENIVHQTLNLAHTYSNEVAVSVVKTTGITVSTRYGKLENVEFNNRS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEECCCCEECEECCCCE
ILDITIFRQQRKGSALSNDLNKKAINRTVAAAADIASYTSPDPYAGIADKELLAFNSMNL
EEEEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCE
ELFHPISLDTKLGVTLASTAEETALKYDKRIIYTEGGRFSSYFTTKVFGNSHGMLQSYTS
EEEECCCCCCCCCEEEECCHHHHHHHHCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHC
SRHSLCCGVIAASNDIMEQNYAYTLSRSFDDLRSAEWVGQECAQRALNHLNPKKLKTMES
CCCCEEEEEEECCCHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
PVLFSAEVATSLFHHLASAIHGDNVFRKSTFLLNDLKKKIFPSWISIKERPHVLKGLGSA
CCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHCCCC
PFDSEGIQTLNRTIVENGILNSWILNSYSARKMGIKNTGHADGIYNWYISYQNLSFMELI
CCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHCCCCCCCCCCCEEEEEEEECCCHHHHHH
KNMQRGLVVTNIMGQGINITTGDYSRGVAGFWVENGDIQYPVNEIAIAGNLKDMFYNIDA
HHHHCCEEEEEECCCCCEEECCCCCCCCEEEEEECCCEECCHHHEEEECCHHHHHEEHHH
IGHDIETRNHIHCGSVLISSMKIAGI
HCCCCCCCCCEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]