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The map label for this gene is lysA [H]

Identifier: 71892045

GI number: 71892045

Start: 309411

End: 310700

Strand: Direct

Name: lysA [H]

Synonym: BPEN_271

Alternate gene names: 71892045

Gene position: 309411-310700 (Clockwise)

Preceding gene: 71892044

Following gene: 71892046

Centisome position: 39.08

GC content: 31.86

Gene sequence:

>1290_bases
GTGACATATAATATCTTTGCGCGAACAAGTGCTCTTACCTATGAAAGCTTAAAAAAATTACATAAAAAATATAAAGGTCC
AGTATGGGTATACGATGCATCGATTATAATTAATCGTATCACACAATTAAAACAATTTGATGTTATACGGTACGCTCAAA
AATCTTGTTCTAATATTCATATTTTACGATTAATGCATAATTATGAAGTTAAAGTAGATGCTGTTTCTTTAGGCGAGATC
GAACGAGCATTATTAGCTGGTTTTAAAGCGGGAAAACAAAGCAATGAAATAGTTTTCACTGCTGATATTTTAGAAGAAGA
AACATTATTAAGAATATCAGAACTAAATATTGTTGTTAATGCAGGATCGATAGATATGTTAGCACAATTAGGAGCTTGTT
CTCCTGGACATAAAATATGGTTACGTATTAATCCTGGATTTGGACATGGACATAATCAAAAAACTAATACTGGAGGAGAA
AATAGCAAGCATGGAATTTGGCATGAAGATATACCAATAGCTTTATCTTATATTCATCATTATGATCTACAGTTAATCGG
ACTGCATATGCATATTGGTTCTGGAGTACGGTACGATCATTTATCTAAAGTATGTAATGCGATGGTCCAGCAGATTTTGA
AATATAAAATAGATGTAGATGTTATTTCTGCTGGAGGAGGATTAACAATACCATATGAACATAATGATATGGTTTTAGAT
GTAAATCATTATTTTCGATTATGGAATAACGCGAGAAAATACATTAGCCAATATTTAAATCACACAGTAACATTAGAAAT
AGAACCTGGTCGTTTTCTTGTGGCTGAATCAGGAATATTAATTACACAGATTAGAGCGGTAAAAAACATGGGTAATCGTC
ATTTTGTATTAATAGACGCAGGGTATAATGATTTAATGCGCCCAGTTATGTATGGTAGTTATCATCATATTTCATTAGTA
CCTGGAGATAATCGCAGCGTTATTTTAGAAACATTATGCGATACCGTTGTTGGTGGTCCACTATGTGAATCTGGAGATAT
TTTTACACAAAATATGAATGGAACAATATTAGCACGTAAATTACCTTGTTCAGCAAAAGTAGGAGATTATTTAATATTTC
ATGACACTGGTGCATACGGCGCTTCTATGTCTTCTAATTATAATACACGTCCGTTACTACCAGAAGTTTTATTTGAAAAT
GGACAAATTCGTCAAATTCGCCGAAAACAAAAACTAGAAGATTTATTTATGTTGGAAACAATGGAAAAATTTAATAAGGA
AAATTGTTGA

Upstream 100 bases:

>100_bases
AAACCTATTTTTTACGATTTTCGACTATATATTCAAAATATAATTTCGAAATATTTTGATATTTAAAATATATATCAAAA
AAAGATAATGGGAATATAGC

Downstream 100 bases:

>100_bases
AATTATCGAATATCATAAATATGACACTATATAAAATTATTTATTAAAAACTTATTATTTAGTATATGGTAAAATACCAG
ATTAAATGATTTAAATATAC

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTYNIFARTSALTYESLKKLHKKYKGPVWVYDASIIINRITQLKQFDVIRYAQKSCSNIHILRLMHNYEVKVDAVSLGEI
ERALLAGFKAGKQSNEIVFTADILEEETLLRISELNIVVNAGSIDMLAQLGACSPGHKIWLRINPGFGHGHNQKTNTGGE
NSKHGIWHEDIPIALSYIHHYDLQLIGLHMHIGSGVRYDHLSKVCNAMVQQILKYKIDVDVISAGGGLTIPYEHNDMVLD
VNHYFRLWNNARKYISQYLNHTVTLEIEPGRFLVAESGILITQIRAVKNMGNRHFVLIDAGYNDLMRPVMYGSYHHISLV
PGDNRSVILETLCDTVVGGPLCESGDIFTQNMNGTILARKLPCSAKVGDYLIFHDTGAYGASMSSNYNTRPLLPEVLFEN
GQIRQIRRKQKLEDLFMLETMEKFNKENC

Sequences:

>Translated_429_residues
MTYNIFARTSALTYESLKKLHKKYKGPVWVYDASIIINRITQLKQFDVIRYAQKSCSNIHILRLMHNYEVKVDAVSLGEI
ERALLAGFKAGKQSNEIVFTADILEEETLLRISELNIVVNAGSIDMLAQLGACSPGHKIWLRINPGFGHGHNQKTNTGGE
NSKHGIWHEDIPIALSYIHHYDLQLIGLHMHIGSGVRYDHLSKVCNAMVQQILKYKIDVDVISAGGGLTIPYEHNDMVLD
VNHYFRLWNNARKYISQYLNHTVTLEIEPGRFLVAESGILITQIRAVKNMGNRHFVLIDAGYNDLMRPVMYGSYHHISLV
PGDNRSVILETLCDTVVGGPLCESGDIFTQNMNGTILARKLPCSAKVGDYLIFHDTGAYGASMSSNYNTRPLLPEVLFEN
GQIRQIRRKQKLEDLFMLETMEKFNKENC
>Mature_428_residues
TYNIFARTSALTYESLKKLHKKYKGPVWVYDASIIINRITQLKQFDVIRYAQKSCSNIHILRLMHNYEVKVDAVSLGEIE
RALLAGFKAGKQSNEIVFTADILEEETLLRISELNIVVNAGSIDMLAQLGACSPGHKIWLRINPGFGHGHNQKTNTGGEN
SKHGIWHEDIPIALSYIHHYDLQLIGLHMHIGSGVRYDHLSKVCNAMVQQILKYKIDVDVISAGGGLTIPYEHNDMVLDV
NHYFRLWNNARKYISQYLNHTVTLEIEPGRFLVAESGILITQIRAVKNMGNRHFVLIDAGYNDLMRPVMYGSYHHISLVP
GDNRSVILETLCDTVVGGPLCESGDIFTQNMNGTILARKLPCSAKVGDYLIFHDTGAYGASMSSNYNTRPLLPEVLFENG
QIRQIRRKQKLEDLFMLETMEKFNKENC

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Escherichia coli, GI1789203, Length=412, Percent_Identity=62.621359223301, Blast_Score=565, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 48549; Mature: 48417

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYNIFARTSALTYESLKKLHKKYKGPVWVYDASIIINRITQLKQFDVIRYAQKSCSNIH
CEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ILRLMHNYEVKVDAVSLGEIERALLAGFKAGKQSNEIVFTADILEEETLLRISELNIVVN
EEEEEECCEEEEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEHHHCCCHHEEEEEEEEEEE
AGSIDMLAQLGACSPGHKIWLRINPGFGHGHNQKTNTGGENSKHGIWHEDIPIALSYIHH
CCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
YDLQLIGLHMHIGSGVRYDHLSKVCNAMVQQILKYKIDVDVISAGGGLTIPYEHNDMVLD
CCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCEEEE
VNHYFRLWNNARKYISQYLNHTVTLEIEPGRFLVAESGILITQIRAVKNMGNRHFVLIDA
HHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCCCEEHHHHHHCCCCEEEEEEEC
GYNDLMRPVMYGSYHHISLVPGDNRSVILETLCDTVVGGPLCESGDIFTQNMNGTILARK
CHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEE
LPCSAKVGDYLIFHDTGAYGASMSSNYNTRPLLPEVLFENGQIRQIRRKQKLEDLFMLET
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
MEKFNKENC
HHHHCCCCC
>Mature Secondary Structure 
TYNIFARTSALTYESLKKLHKKYKGPVWVYDASIIINRITQLKQFDVIRYAQKSCSNIH
EEEEEECCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ILRLMHNYEVKVDAVSLGEIERALLAGFKAGKQSNEIVFTADILEEETLLRISELNIVVN
EEEEEECCEEEEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEHHHCCCHHEEEEEEEEEEE
AGSIDMLAQLGACSPGHKIWLRINPGFGHGHNQKTNTGGENSKHGIWHEDIPIALSYIHH
CCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
YDLQLIGLHMHIGSGVRYDHLSKVCNAMVQQILKYKIDVDVISAGGGLTIPYEHNDMVLD
CCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCEEEE
VNHYFRLWNNARKYISQYLNHTVTLEIEPGRFLVAESGILITQIRAVKNMGNRHFVLIDA
HHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCCCEEHHHHHHCCCCEEEEEEEC
GYNDLMRPVMYGSYHHISLVPGDNRSVILETLCDTVVGGPLCESGDIFTQNMNGTILARK
CHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEE
LPCSAKVGDYLIFHDTGAYGASMSSNYNTRPLLPEVLFENGQIRQIRRKQKLEDLFMLET
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHH
MEKFNKENC
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6350601; 9278503 [H]