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The map label for this gene is coaE

Identifier: 71891936

GI number: 71891936

Start: 189805

End: 190443

Strand: Reverse

Name: coaE

Synonym: BPEN_153

Alternate gene names: 71891936

Gene position: 190443-189805 (Counterclockwise)

Preceding gene: 71891939

Following gene: 71891920

Centisome position: 24.06

GC content: 28.33

Gene sequence:

>639_bases
ATGTCTTATATTGTTGCGCTTACCGGTGGTATTTGTTCTGGAAAAAGTGTTGTTGCTAAAAAATTTTCTAATTTATCAAA
GAAAGTATCCGTAATAGATGCTGATGTGATTTCTAAAAACATCACGCAACCTGGCAGCATTGCTTTACGTATGATAACAA
AACATTTTGGACCCCACATTTTATTTTCTAATGGATCATTAAATAGATCCATGTTAAAAAAAATTATTTTTTTCAATCCT
AAAGATAAAGAATGGCTTGAACAATTGTTGCATCCGCTTATTAGAAAAGAAACGCAAAAAACAATAAATATCTTATCCAA
TCGATCATCTTATATTTTATGGGTTGTTCCATTGTTAATAGAAAATAATTTACAAAAATATGCAGATCACATACTAATGA
TAGATGTACACGTTGATATTCAGTTAAATCGAATTATCAGTAGAGATAAAATACACAAACAATATGCTGAAAATATTTTA
TTATCACAAGTATCCCGTCAGCATAGATTAAACTATGCTGATAATGTTATTGAAAATAACAAAAGTATTGACGGAATGAC
ACAACATATTCATAATCTCCATCGAGATTATCTTAAGGCAGAAAAAACAACTACTAAAAAAACTATTTTTAGTAAATGA

Upstream 100 bases:

>100_bases
TCAGATATCGTTCTAAATATTCTTAATATTAATTTAATTTTATAATTTTTATAAAAAAATTTCATAAAAACATTTTTTAT
TTAATAACACACATCACATT

Downstream 100 bases:

>100_bases
AATAACACGTAAAATTATACCATATTTATATTGTAGCAAAAAAAACAGCATACGAAATTGTTTGTTATAAATAACACAAC
AACGTTTACATAAATTATAA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSYIVALTGGICSGKSVVAKKFSNLSKKVSVIDADVISKNITQPGSIALRMITKHFGPHILFSNGSLNRSMLKKIIFFNP
KDKEWLEQLLHPLIRKETQKTINILSNRSSYILWVVPLLIENNLQKYADHILMIDVHVDIQLNRIISRDKIHKQYAENIL
LSQVSRQHRLNYADNVIENNKSIDGMTQHIHNLHRDYLKAEKTTTKKTIFSK

Sequences:

>Translated_212_residues
MSYIVALTGGICSGKSVVAKKFSNLSKKVSVIDADVISKNITQPGSIALRMITKHFGPHILFSNGSLNRSMLKKIIFFNP
KDKEWLEQLLHPLIRKETQKTINILSNRSSYILWVVPLLIENNLQKYADHILMIDVHVDIQLNRIISRDKIHKQYAENIL
LSQVSRQHRLNYADNVIENNKSIDGMTQHIHNLHRDYLKAEKTTTKKTIFSK
>Mature_211_residues
SYIVALTGGICSGKSVVAKKFSNLSKKVSVIDADVISKNITQPGSIALRMITKHFGPHILFSNGSLNRSMLKKIIFFNPK
DKEWLEQLLHPLIRKETQKTINILSNRSSYILWVVPLLIENNLQKYADHILMIDVHVDIQLNRIISRDKIHKQYAENILL
SQVSRQHRLNYADNVIENNKSIDGMTQHIHNLHRDYLKAEKTTTKKTIFSK

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=180, Percent_Identity=35.5555555555556, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI191252795, Length=180, Percent_Identity=35.5555555555556, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI110227607, Length=167, Percent_Identity=26.9461077844311, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI110227605, Length=167, Percent_Identity=26.9461077844311, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI110227603, Length=167, Percent_Identity=26.9461077844311, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI110227601, Length=167, Percent_Identity=26.9461077844311, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI205277394, Length=167, Percent_Identity=26.9461077844311, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1786292, Length=199, Percent_Identity=46.7336683417085, Blast_Score=188, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17554944, Length=193, Percent_Identity=29.5336787564767, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320402, Length=196, Percent_Identity=31.1224489795918, Blast_Score=99, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24644728, Length=199, Percent_Identity=32.6633165829146, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24658602, Length=165, Percent_Identity=29.6969696969697, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_BLOPB (Q493P4)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277666.1
- ProteinModelPortal:   Q493P4
- SMR:   Q493P4
- STRING:   Q493P4
- GeneID:   3563088
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_153
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   LSAKVVH
- BioCyc:   CBLO291272:BPEN_153-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 24383; Mature: 24252

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: PS51219 DPCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYIVALTGGICSGKSVVAKKFSNLSKKVSVIDADVISKNITQPGSIALRMITKHFGPHI
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEE
LFSNGSLNRSMLKKIIFFNPKDKEWLEQLLHPLIRKETQKTINILSNRSSYILWVVPLLI
EEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
ENNLQKYADHILMIDVHVDIQLNRIISRDKIHKQYAENILLSQVSRQHRLNYADNVIENN
HCCHHHHHCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
KSIDGMTQHIHNLHRDYLKAEKTTTKKTIFSK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYIVALTGGICSGKSVVAKKFSNLSKKVSVIDADVISKNITQPGSIALRMITKHFGPHI
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEE
LFSNGSLNRSMLKKIIFFNPKDKEWLEQLLHPLIRKETQKTINILSNRSSYILWVVPLLI
EEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
ENNLQKYADHILMIDVHVDIQLNRIISRDKIHKQYAENILLSQVSRQHRLNYADNVIENN
HCCHHHHHCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
KSIDGMTQHIHNLHRDYLKAEKTTTKKTIFSK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA