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The map label for this gene is pdxA [H]

Identifier: 71891914

GI number: 71891914

Start: 158972

End: 159991

Strand: Reverse

Name: pdxA [H]

Synonym: BPEN_131

Alternate gene names: 71891914

Gene position: 159991-158972 (Counterclockwise)

Preceding gene: 71891915

Following gene: 71891913

Centisome position: 20.21

GC content: 32.25

Gene sequence:

>1020_bases
ATGATAAAAAAAAATAAACAATTTCAACGCATTGTGCTTACTACGGGAGAACCGGCTGGGATCGGTCCTGACATAATTAT
TATGAGCGCACAAAAGAAATGGCCTGTAGAGTTGGTTGTGTGTGCAGACCCTAATTTACTATTAGATAGAGCAAAGCAAA
TAAATCTGCCTCTAAGATTACGTTCTTATCATTCTAAAAAAATAGCATCTCCTTGTATGCCCGGAGAATTATCTGTATTA
AAAATGTTACTTCCACAAAAAACTATACCTGGTCAATTAAATGTTAATAACAATAATTATGTTGTTCATACTCTAACAAG
AGCATCACAAGGATGTTTAAATGGAGAATTTTCAGCATTAGTGACCGGTCCTATACATAAAGCTATTCTTAATAAAGGAA
ACATAGCATTCAGTGGGCACACTGAATTTTTATCTCAAATCAACAAATGTAAAACAACTGTAATGATGCTAAGTAATAGA
AAATTACGTGTTGCTTTAGCCACTACCCATATACCTATATTATCTGTTCCAAAAATGATTACTCAAAAATCTCTTTGCGA
CACTATTTCCACTCTCGCGAAAGGATTAAAAAAATACTTTGGTGTTCCACACCCTAAAATTTATATATGCGGCTTAAATC
CACATTCCGGAGAATCCGGCTATATAGGAAAAGAAGAGATTAATATCATTATACCTGCTTTAAATATTTTAAAGAAAAAA
ATTAATTGTGAACTAATAGGTCCTTTGTCAGCTGATACAATATTTCAGAAAAAATATATTCAACATGCAGACGTAATATT
AGCTATGTATCATGATCAAGGTTTACCTGTTTTAAAATATTCTGGATTTGGTCAATCAGTAAATATTACTTTAGGATTAC
CTTTTATTAGAACCTCTGTAGATCACGGTACTGCTCTTGAACTATCTGGAACAGGAACAGCGCTACCTGATAGTATGATT
ATGGCTATTACAGTTGCAATTAAAATGTTGAGTCATCATTATGAAAAAAATATACTATAA

Upstream 100 bases:

>100_bases
CGTGCTTATTTATATTTATTAAATAACAAATTTGATGAAATTATGAAAAATTGGATTCAAGAATTACGATCCGAATCATA
TATTAAGATCATTAACTAAA

Downstream 100 bases:

>100_bases
AAATCATCTTATAAAAAAAAAATGGAGCCAAGTATTCCTTAAAGATCAAAATGTTATTGATACTATTGTTAAAACTATTA
ATCCTAAAAAACATCAAAAA

Product: pyridoxine phosphate biosynthetic protein PdxJ-PdxA subunit, NAD-dependent dehydrogenase/carboxylase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIKKNKQFQRIVLTTGEPAGIGPDIIIMSAQKKWPVELVVCADPNLLLDRAKQINLPLRLRSYHSKKIASPCMPGELSVL
KMLLPQKTIPGQLNVNNNNYVVHTLTRASQGCLNGEFSALVTGPIHKAILNKGNIAFSGHTEFLSQINKCKTTVMMLSNR
KLRVALATTHIPILSVPKMITQKSLCDTISTLAKGLKKYFGVPHPKIYICGLNPHSGESGYIGKEEINIIIPALNILKKK
INCELIGPLSADTIFQKKYIQHADVILAMYHDQGLPVLKYSGFGQSVNITLGLPFIRTSVDHGTALELSGTGTALPDSMI
MAITVAIKMLSHHYEKNIL

Sequences:

>Translated_339_residues
MIKKNKQFQRIVLTTGEPAGIGPDIIIMSAQKKWPVELVVCADPNLLLDRAKQINLPLRLRSYHSKKIASPCMPGELSVL
KMLLPQKTIPGQLNVNNNNYVVHTLTRASQGCLNGEFSALVTGPIHKAILNKGNIAFSGHTEFLSQINKCKTTVMMLSNR
KLRVALATTHIPILSVPKMITQKSLCDTISTLAKGLKKYFGVPHPKIYICGLNPHSGESGYIGKEEINIIIPALNILKKK
INCELIGPLSADTIFQKKYIQHADVILAMYHDQGLPVLKYSGFGQSVNITLGLPFIRTSVDHGTALELSGTGTALPDSMI
MAITVAIKMLSHHYEKNIL
>Mature_339_residues
MIKKNKQFQRIVLTTGEPAGIGPDIIIMSAQKKWPVELVVCADPNLLLDRAKQINLPLRLRSYHSKKIASPCMPGELSVL
KMLLPQKTIPGQLNVNNNNYVVHTLTRASQGCLNGEFSALVTGPIHKAILNKGNIAFSGHTEFLSQINKCKTTVMMLSNR
KLRVALATTHIPILSVPKMITQKSLCDTISTLAKGLKKYFGVPHPKIYICGLNPHSGESGYIGKEEINIIIPALNILKKK
INCELIGPLSADTIFQKKYIQHADVILAMYHDQGLPVLKYSGFGQSVNITLGLPFIRTSVDHGTALELSGTGTALPDSMI
MAITVAIKMLSHHYEKNIL

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=322, Percent_Identity=56.2111801242236, Blast_Score=378, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 37203; Mature: 37203

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKNKQFQRIVLTTGEPAGIGPDIIIMSAQKKWPVELVVCADPNLLLDRAKQINLPLRL
CCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHCCCCEEE
RSYHSKKIASPCMPGELSVLKMLLPQKTIPGQLNVNNNNYVVHTLTRASQGCLNGEFSAL
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEE
VTGPIHKAILNKGNIAFSGHTEFLSQINKCKTTVMMLSNRKLRVALATTHIPILSVPKMI
EECHHHHHHHCCCCEEECCHHHHHHHHHHHHHEEEEECCCEEEEEEEEECCCHHHCHHHH
TQKSLCDTISTLAKGLKKYFGVPHPKIYICGLNPHSGESGYIGKEEINIIIPALNILKKK
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECHHHHHHH
INCELIGPLSADTIFQKKYIQHADVILAMYHDQGLPVLKYSGFGQSVNITLGLPFIRTSV
CCEEEECCCCHHHHHHHHHHHHHCEEEEEEECCCCCEEEECCCCCEEEEEEECCHHEECC
DHGTALELSGTGTALPDSMIMAITVAIKMLSHHYEKNIL
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKKNKQFQRIVLTTGEPAGIGPDIIIMSAQKKWPVELVVCADPNLLLDRAKQINLPLRL
CCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHCCCCEEE
RSYHSKKIASPCMPGELSVLKMLLPQKTIPGQLNVNNNNYVVHTLTRASQGCLNGEFSAL
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEE
VTGPIHKAILNKGNIAFSGHTEFLSQINKCKTTVMMLSNRKLRVALATTHIPILSVPKMI
EECHHHHHHHCCCCEEECCHHHHHHHHHHHHHEEEEECCCEEEEEEEEECCCHHHCHHHH
TQKSLCDTISTLAKGLKKYFGVPHPKIYICGLNPHSGESGYIGKEEINIIIPALNILKKK
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECHHHHHHH
INCELIGPLSADTIFQKKYIQHADVILAMYHDQGLPVLKYSGFGQSVNITLGLPFIRTSV
CCEEEECCCCHHHHHHHHHHHHHCEEEEEEECCCCCEEEECCCCCEEEEEEECCHHEECC
DHGTALELSGTGTALPDSMIMAITVAIKMLSHHYEKNIL
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA