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The map label for this gene is apaH [H]

Identifier: 71891912

GI number: 71891912

Start: 156974

End: 157795

Strand: Reverse

Name: apaH [H]

Synonym: BPEN_129

Alternate gene names: 71891912

Gene position: 157795-156974 (Counterclockwise)

Preceding gene: 71891913

Following gene: 71891903

Centisome position: 19.93

GC content: 30.66

Gene sequence:

>822_bases
ATGTCTACTTATTTTATTGGAGATGTCCACGGATGTTACAAACACTTACAAACTATACTAGATCATGTATGCTTTAATCC
TAAAGTTGATACTCTGCATTTTACCGGAGATTTAATCGCCAGAGGACCAAATTCATTAGAGGTATTGCGTTTAGTCTATG
CATTTAAAAAAAGTGCTTCCATAGTGTTAGGTAATCATGAGCTACATTTATTAAAAACATATTTTGGAATAAATAGTAGA
AAACGTAAAGATTATTTTGATGCGATATTCAATGCTCCAGATCTAGAAGAATTAATTAATTGGTTACGTCATCAACCTAT
GTTATTCATAGATGAAAATAAAAAGATATTAATGACCCATGCAGGCATTAGTCCTAATTGGAATATTAACAATACTAAAA
AATATGCCCAAGAAATAGAAGAAATTTTAGTTAGCGACCATTATTTTCTGCTTTTTAAAAAAAGCATACATGACAATGTA
TCTGATACATATCAGATACATAATAATAAATTAAAACAAATACAAGAAAACATAAATGTATTCACACGAATGCGTTATAT
TTATCTAAATGGTCAATTAGATTTAAAATACAAAGGAGCTCCTAAGGATGCCCCAAAAAATATATATCCATGGTTTTCTT
TAAACAAATTAGTTGATCCCACATATAATATAATTTTTGGTCATTGGGCATCTTTAGGAGAAATAGAAATACCAGATGGT
ATTTATGGATTAGATTCTGGTTGTTGTTGGGGAGGGGCGCTGACCTTATTGCGATGGGAAGACAAAAAGATTGTATGCAT
ACCTTGTGACCCATCTACTTAA

Upstream 100 bases:

>100_bases
TAAAAAAGGAAAGTTTATCTTAATACAAAATATTAAAAATATTATGATATATTATGTATTTGATTAATTTTTATTGTAAA
AAAAATCTATAATCACCCAA

Downstream 100 bases:

>100_bases
CTTAAAAATAATTAAATTTGATGATTATTTATACATATTCTATACAAATAGAAATAAATTAGTACCATATTGTAATTATC
ACTCTTTTAAAAATAATTTA

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSTYFIGDVHGCYKHLQTILDHVCFNPKVDTLHFTGDLIARGPNSLEVLRLVYAFKKSASIVLGNHELHLLKTYFGINSR
KRKDYFDAIFNAPDLEELINWLRHQPMLFIDENKKILMTHAGISPNWNINNTKKYAQEIEEILVSDHYFLLFKKSIHDNV
SDTYQIHNNKLKQIQENINVFTRMRYIYLNGQLDLKYKGAPKDAPKNIYPWFSLNKLVDPTYNIIFGHWASLGEIEIPDG
IYGLDSGCCWGGALTLLRWEDKKIVCIPCDPST

Sequences:

>Translated_273_residues
MSTYFIGDVHGCYKHLQTILDHVCFNPKVDTLHFTGDLIARGPNSLEVLRLVYAFKKSASIVLGNHELHLLKTYFGINSR
KRKDYFDAIFNAPDLEELINWLRHQPMLFIDENKKILMTHAGISPNWNINNTKKYAQEIEEILVSDHYFLLFKKSIHDNV
SDTYQIHNNKLKQIQENINVFTRMRYIYLNGQLDLKYKGAPKDAPKNIYPWFSLNKLVDPTYNIIFGHWASLGEIEIPDG
IYGLDSGCCWGGALTLLRWEDKKIVCIPCDPST
>Mature_272_residues
STYFIGDVHGCYKHLQTILDHVCFNPKVDTLHFTGDLIARGPNSLEVLRLVYAFKKSASIVLGNHELHLLKTYFGINSRK
RKDYFDAIFNAPDLEELINWLRHQPMLFIDENKKILMTHAGISPNWNINNTKKYAQEIEEILVSDHYFLLFKKSIHDNVS
DTYQIHNNKLKQIQENINVFTRMRYIYLNGQLDLKYKGAPKDAPKNIYPWFSLNKLVDPTYNIIFGHWASLGEIEIPDGI
YGLDSGCCWGGALTLLRWEDKKIVCIPCDPST

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=270, Percent_Identity=48.1481481481481, Blast_Score=278, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31625; Mature: 31494

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTYFIGDVHGCYKHLQTILDHVCFNPKVDTLHFTGDLIARGPNSLEVLRLVYAFKKSAS
CCEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEECCHHEECCCCHHHHHHHHHHHHCCCE
IVLGNHELHLLKTYFGINSRKRKDYFDAIFNAPDLEELINWLRHQPMLFIDENKKILMTH
EEECCCCEEEEEEHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCCEEEEEE
AGISPNWNINNTKKYAQEIEEILVSDHYFLLFKKSIHDNVSDTYQIHNNKLKQIQENINV
CCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHEEEHHHHHHHHHHHHHH
FTRMRYIYLNGQLDLKYKGAPKDAPKNIYPWFSLNKLVDPTYNIIFGHWASLGEIEIPDG
EEEEEEEEECCEEEEEECCCCCCCCCCCCCCEECCHHCCCCCEEEEECCCCCCCEECCCC
IYGLDSGCCWGGALTLLRWEDKKIVCIPCDPST
CCCCCCCCCCCCEEEEEEECCCEEEEEECCCCC
>Mature Secondary Structure 
STYFIGDVHGCYKHLQTILDHVCFNPKVDTLHFTGDLIARGPNSLEVLRLVYAFKKSAS
CEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEECCHHEECCCCHHHHHHHHHHHHCCCE
IVLGNHELHLLKTYFGINSRKRKDYFDAIFNAPDLEELINWLRHQPMLFIDENKKILMTH
EEECCCCEEEEEEHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCCEEEEEE
AGISPNWNINNTKKYAQEIEEILVSDHYFLLFKKSIHDNVSDTYQIHNNKLKQIQENINV
CCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHEEEHHHHHHHHHHHHHH
FTRMRYIYLNGQLDLKYKGAPKDAPKNIYPWFSLNKLVDPTYNIIFGHWASLGEIEIPDG
EEEEEEEEECCEEEEEECCCCCCCCCCCCCCEECCHHCCCCCEEEEECCCCCCCEECCCC
IYGLDSGCCWGGALTLLRWEDKKIVCIPCDPST
CCCCCCCCCCCCEEEEEEECCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA