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The map label for this gene is obgE

Identifier: 71891883

GI number: 71891883

Start: 115536

End: 116558

Strand: Direct

Name: obgE

Synonym: BPEN_098

Alternate gene names: 71891883

Gene position: 115536-116558 (Clockwise)

Preceding gene: 71891882

Following gene: 71891884

Centisome position: 14.59

GC content: 33.04

Gene sequence:

>1023_bases
ATGAAATTTGTTGATATGACCAACATTACGGTTATTGCTGGTAACGGAGGGAATGGGTGTGTTAGTTTTCAAAAATCGGG
AAGAAGAGCTTCTTTTTTGAAGAAACCTAATGGTAGTAATGGAGGAAATGGAGGGGATGTTTGGTTATTAGCAGATCCTA
ATATTAATACTTTAAATTATTTTCATTCTAATTGTGTTTTTAGAGCCGGTCATGGACAAAGTGGCCGTAGCCGTGGTTGT
ACTGGTAAAAGAGGCAAAGATGTTATTGTGAAAGTACCGTGGGGAACTAGAGTAAGTTATAAAAAAACAAATAAATTATT
GGGAGATATGGGTATTCATCACAAACGGTTGATGGTGGCTAAAGGAGGGCGTCATGGTTTGGGAAATGGACATTTTAAAT
CTTCTTTGCATTATTGTAAGGTACTTAATACAAATGGGTCAACAGGAGAGTTCCAACATTTGCTATTAGAATTGCTTCTA
ATAGCAAATGTTGGAATATTTGGATTACCTAATTCTGGAAAATCTAGTTTTATTCGTATAATATCGTCAGCGAAACCAAA
AGTAGCAGATTATCCATTTACTACATTAGTACCGTATTTAGGTGTGGTACAAATTAATAACTATGATAGATTTATTATTG
CGGATATTCCTGGTATTATTAAAGGCGCTTCTCATGGTTTGGGATTAGGAATGCGATTTTTGAAGCATCTAGAACACTGT
CAAATTTTACTGCATTTTATTGATATTGCGCCTGTGGATAATTCCGATCCATTAGAAAATATTATTACTATTCAGCATGA
ATTAAGTAATTACAATGAAAATTTAGTTAGAAAACCTTGTTGGTTAATATTCAATAAAATAGACTTGTTGGAACAACAAG
TGGCGGAAAAAAGGATTAACCATGTTATTAGTTCTTTAAAATGGAAAGGGCGCTATTACTCAATATCTTCTATACATAAT
ACTAATGTATTATCGCTATGTAACAGTATTATGAAGTTTATTATGCATCATACTCACAGTTAA

Upstream 100 bases:

>100_bases
AACAATATGGAATAAATTTTATTATTACAAAATTTACACTAACTTATTAAGTGACAAGTTATTTATACTATAAATATAGA
CGATATGTTAGAGATATATT

Downstream 100 bases:

>100_bases
GAACCAACTCTTATGTATACACAAGACAATGAGTAGGAATCAGGATTAGCTAATTCTATTGTTATTTTAAAACAATACAC
ATAATATACCTTTAAGTTTA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKFVDMTNITVIAGNGGNGCVSFQKSGRRASFLKKPNGSNGGNGGDVWLLADPNINTLNYFHSNCVFRAGHGQSGRSRGC
TGKRGKDVIVKVPWGTRVSYKKTNKLLGDMGIHHKRLMVAKGGRHGLGNGHFKSSLHYCKVLNTNGSTGEFQHLLLELLL
IANVGIFGLPNSGKSSFIRIISSAKPKVADYPFTTLVPYLGVVQINNYDRFIIADIPGIIKGASHGLGLGMRFLKHLEHC
QILLHFIDIAPVDNSDPLENIITIQHELSNYNENLVRKPCWLIFNKIDLLEQQVAEKRINHVISSLKWKGRYYSISSIHN
TNVLSLCNSIMKFIMHHTHS

Sequences:

>Translated_340_residues
MKFVDMTNITVIAGNGGNGCVSFQKSGRRASFLKKPNGSNGGNGGDVWLLADPNINTLNYFHSNCVFRAGHGQSGRSRGC
TGKRGKDVIVKVPWGTRVSYKKTNKLLGDMGIHHKRLMVAKGGRHGLGNGHFKSSLHYCKVLNTNGSTGEFQHLLLELLL
IANVGIFGLPNSGKSSFIRIISSAKPKVADYPFTTLVPYLGVVQINNYDRFIIADIPGIIKGASHGLGLGMRFLKHLEHC
QILLHFIDIAPVDNSDPLENIITIQHELSNYNENLVRKPCWLIFNKIDLLEQQVAEKRINHVISSLKWKGRYYSISSIHN
TNVLSLCNSIMKFIMHHTHS
>Mature_340_residues
MKFVDMTNITVIAGNGGNGCVSFQKSGRRASFLKKPNGSNGGNGGDVWLLADPNINTLNYFHSNCVFRAGHGQSGRSRGC
TGKRGKDVIVKVPWGTRVSYKKTNKLLGDMGIHHKRLMVAKGGRHGLGNGHFKSSLHYCKVLNTNGSTGEFQHLLLELLL
IANVGIFGLPNSGKSSFIRIISSAKPKVADYPFTTLVPYLGVVQINNYDRFIIADIPGIIKGASHGLGLGMRFLKHLEHC
QILLHFIDIAPVDNSDPLENIITIQHELSNYNENLVRKPCWLIFNKIDLLEQQVAEKRINHVISSLKWKGRYYSISSIHN
TNVLSLCNSIMKFIMHHTHS

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=292, Percent_Identity=37.3287671232877, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI111955139, Length=312, Percent_Identity=33.6538461538462, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI111955063, Length=155, Percent_Identity=38.7096774193548, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789574, Length=339, Percent_Identity=53.3923303834808, Blast_Score=354, Evalue=4e-99,
Organism=Escherichia coli, GI1790615, Length=132, Percent_Identity=30.3030303030303, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=304, Percent_Identity=36.5131578947368, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17552324, Length=375, Percent_Identity=28.2666666666667, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=140, Percent_Identity=31.4285714285714, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=162, Percent_Identity=38.2716049382716, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=30.1587301587302, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129375, Length=293, Percent_Identity=34.8122866894198, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24585318, Length=294, Percent_Identity=31.6326530612245, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_BLOPB (Q493U5)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277613.1
- HSSP:   Q5SJ29
- ProteinModelPortal:   Q493U5
- SMR:   Q493U5
- STRING:   Q493U5
- GeneID:   3563179
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_098
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- BioCyc:   CBLO291272:BPEN_098-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 37694; Mature: 37694

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDMTNITVIAGNGGNGCVSFQKSGRRASFLKKPNGSNGGNGGDVWLLADPNINTLNY
CCEEEECEEEEEECCCCCCEEEECCCCCCCHHEECCCCCCCCCCCEEEEEECCCCCEEEE
FHSNCVFRAGHGQSGRSRGCTGKRGKDVIVKVPWGTRVSYKKTNKLLGDMGIHHKRLMVA
ECCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEE
KGGRHGLGNGHFKSSLHYCKVLNTNGSTGEFQHLLLELLLIANVGIFGLPNSGKSSFIRI
CCCCCCCCCCCHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHH
ISSAKPKVADYPFTTLVPYLGVVQINNYDRFIIADIPGIIKGASHGLGLGMRFLKHLEHC
HHCCCCCCCCCCHHHHHHHHCEEEECCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHHHH
QILLHFIDIAPVDNSDPLENIITIQHELSNYNENLVRKPCWLIFNKIDLLEQQVAEKRIN
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
HVISSLKWKGRYYSISSIHNTNVLSLCNSIMKFIMHHTHS
HHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFVDMTNITVIAGNGGNGCVSFQKSGRRASFLKKPNGSNGGNGGDVWLLADPNINTLNY
CCEEEECEEEEEECCCCCCEEEECCCCCCCHHEECCCCCCCCCCCEEEEEECCCCCEEEE
FHSNCVFRAGHGQSGRSRGCTGKRGKDVIVKVPWGTRVSYKKTNKLLGDMGIHHKRLMVA
ECCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEE
KGGRHGLGNGHFKSSLHYCKVLNTNGSTGEFQHLLLELLLIANVGIFGLPNSGKSSFIRI
CCCCCCCCCCCHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHH
ISSAKPKVADYPFTTLVPYLGVVQINNYDRFIIADIPGIIKGASHGLGLGMRFLKHLEHC
HHCCCCCCCCCCHHHHHHHHCEEEECCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHHHH
QILLHFIDIAPVDNSDPLENIITIQHELSNYNENLVRKPCWLIFNKIDLLEQQVAEKRIN
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
HVISSLKWKGRYYSISSIHNTNVLSLCNSIMKFIMHHTHS
HHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA