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The map label for this gene is hflC [H]

Identifier: 71891871

GI number: 71891871

Start: 100556

End: 101584

Strand: Direct

Name: hflC [H]

Synonym: BPEN_085

Alternate gene names: 71891871

Gene position: 100556-101584 (Clockwise)

Preceding gene: 71891870

Following gene: 71891872

Centisome position: 12.7

GC content: 33.62

Gene sequence:

>1029_bases
ATGATACGAAATTTTTTTTCATTTGTTATATGTGTAATAGTAATATTATTTTTTTCTTTATTTACAATAGAAGAGGGGCA
TAAGGGTATTATATTGCGTTTTGGTAAAGTATTACGCGATGCAGATAACAATTCATTAATTTACAATCCAGGATTGCATA
TAAAAATTCCATTTATTGAGACAATAAAAATTTTAGATTCACGTATTCAGACTATGGACAATCAAGCAGATCGCTTTGTT
ACTATGGAAAAAAAAGATTTAATTATTGATTCTTATGTAAAATGGCGTATTAGCGATTTGAGTCGATATTATTTAGCAAC
AGGAGGGGGTGATATTAGCCAAGCAGAAGTACTGATAAAACGAAAATTTTCCGACCGTTTACGTTCAGAATTAGGGAGAT
TGAATGTTCAAGGTATTGTAACAGATTCTCGAAATAAATTAATGACCGATGTACGTGCATCGTTAAATCATGGAACTTCA
GGAGAGGAAGCGTCAGGATTTCATTGTAATCATGACATTAAAAAGTTTCATTTTCATTCTAAAAATTATGACTCGTCAAT
GCAAGAACAATATCGTGTTTCTGATTTGGTTAATCCAAATAGTATGGCTGCATTGGGCATTGAGATAGTGGATGTACGAA
TCAAGCAAATTAATTTGCCAACAGAAGTATCTGATGCAATTTATCAACGTATGCGTGCAGAACGCGATGCTGTTGCTAGA
CGCCATAGATCACAGGGACGAGAAGAAGCGGAAAAATTACGTGCTACAGCAGATTATGAAGTAACACGTACTCTAGCTGA
GGCTAAACGTCAGTCATTAATCATTCGGGGTGAAGCTGACGCAGAAACTGCTAAACTATATGCTACTACTTTTAATGAAG
ACCCTTCATTTTATGCTTTAGTACGTACCTTACGTGCATATGAAAATAGTTTTAAGAAAAATAATAATGATCTTATGGTG
TTAAGCGCAGAAACTGATTTTTTACGTTTTATGAAATCACCAAAAAGTACTACCGGGCTTAATAATTAA

Upstream 100 bases:

>100_bases
GTCTCGTCATACAAATTCTATACCTAAAGAAAAAGTATTAGACCAAAGACAGGCTAATGTACAACGTGTTGATATTGCGC
GCAAAGGGAGAGAGTCGTAG

Downstream 100 bases:

>100_bases
TTATGTAGTTAAAGATGTTCGCATATTCTTGGATAGTTATTATTCGTTATGTTTGATATATAGAGTATAGAGCAAATATT
ATATATGGTGTATTTCATAG

Product: FtsH protease regulator HflC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MIRNFFSFVICVIVILFFSLFTIEEGHKGIILRFGKVLRDADNNSLIYNPGLHIKIPFIETIKILDSRIQTMDNQADRFV
TMEKKDLIIDSYVKWRISDLSRYYLATGGGDISQAEVLIKRKFSDRLRSELGRLNVQGIVTDSRNKLMTDVRASLNHGTS
GEEASGFHCNHDIKKFHFHSKNYDSSMQEQYRVSDLVNPNSMAALGIEIVDVRIKQINLPTEVSDAIYQRMRAERDAVAR
RHRSQGREEAEKLRATADYEVTRTLAEAKRQSLIIRGEADAETAKLYATTFNEDPSFYALVRTLRAYENSFKKNNNDLMV
LSAETDFLRFMKSPKSTTGLNN

Sequences:

>Translated_342_residues
MIRNFFSFVICVIVILFFSLFTIEEGHKGIILRFGKVLRDADNNSLIYNPGLHIKIPFIETIKILDSRIQTMDNQADRFV
TMEKKDLIIDSYVKWRISDLSRYYLATGGGDISQAEVLIKRKFSDRLRSELGRLNVQGIVTDSRNKLMTDVRASLNHGTS
GEEASGFHCNHDIKKFHFHSKNYDSSMQEQYRVSDLVNPNSMAALGIEIVDVRIKQINLPTEVSDAIYQRMRAERDAVAR
RHRSQGREEAEKLRATADYEVTRTLAEAKRQSLIIRGEADAETAKLYATTFNEDPSFYALVRTLRAYENSFKKNNNDLMV
LSAETDFLRFMKSPKSTTGLNN
>Mature_342_residues
MIRNFFSFVICVIVILFFSLFTIEEGHKGIILRFGKVLRDADNNSLIYNPGLHIKIPFIETIKILDSRIQTMDNQADRFV
TMEKKDLIIDSYVKWRISDLSRYYLATGGGDISQAEVLIKRKFSDRLRSELGRLNVQGIVTDSRNKLMTDVRASLNHGTS
GEEASGFHCNHDIKKFHFHSKNYDSSMQEQYRVSDLVNPNSMAALGIEIVDVRIKQINLPTEVSDAIYQRMRAERDAVAR
RHRSQGREEAEKLRATADYEVTRTLAEAKRQSLIIRGEADAETAKLYATTFNEDPSFYALVRTLRAYENSFKKNNNDLMV
LSAETDFLRFMKSPKSTTGLNN

Specific function: HflC and HflK govern the stability of phage lambda cII protein and have been proposed to encode or regulate a cII- specific protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=322, Percent_Identity=67.3913043478261, Blast_Score=448, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 39212; Mature: 39212

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRNFFSFVICVIVILFFSLFTIEEGHKGIILRFGKVLRDADNNSLIYNPGLHIKIPFIE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEECCCCEEEECHHH
TIKILDSRIQTMDNQADRFVTMEKKDLIIDSYVKWRISDLSRYYLATGGGDISQAEVLIK
HHHHHHHHHHHHCCCCHHEEEECCHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHH
RKFSDRLRSELGRLNVQGIVTDSRNKLMTDVRASLNHGTSGEEASGFHCNHDIKKFHFHS
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEECC
KNYDSSMQEQYRVSDLVNPNSMAALGIEIVDVRIKQINLPTEVSDAIYQRMRAERDAVAR
CCCCHHHHHHHHHHHCCCCCCHHHHCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
RHRSQGREEAEKLRATADYEVTRTLAEAKRQSLIIRGEADAETAKLYATTFNEDPSFYAL
HHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECCCCCHHHHH
VRTLRAYENSFKKNNNDLMVLSAETDFLRFMKSPKSTTGLNN
HHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIRNFFSFVICVIVILFFSLFTIEEGHKGIILRFGKVLRDADNNSLIYNPGLHIKIPFIE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEECCCCEEEECHHH
TIKILDSRIQTMDNQADRFVTMEKKDLIIDSYVKWRISDLSRYYLATGGGDISQAEVLIK
HHHHHHHHHHHHCCCCHHEEEECCHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHH
RKFSDRLRSELGRLNVQGIVTDSRNKLMTDVRASLNHGTSGEEASGFHCNHDIKKFHFHS
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEECC
KNYDSSMQEQYRVSDLVNPNSMAALGIEIVDVRIKQINLPTEVSDAIYQRMRAERDAVAR
CCCCHHHHHHHHHHHCCCCCCHHHHCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
RHRSQGREEAEKLRATADYEVTRTLAEAKRQSLIIRGEADAETAKLYATTFNEDPSFYAL
HHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECCCCCHHHHH
VRTLRAYENSFKKNNNDLMVLSAETDFLRFMKSPKSTTGLNN
HHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]