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The map label for this gene is plsC [H]

Identifier: 71891856

GI number: 71891856

Start: 80554

End: 81291

Strand: Direct

Name: plsC [H]

Synonym: BPEN_068

Alternate gene names: 71891856

Gene position: 80554-81291 (Clockwise)

Preceding gene: 71891855

Following gene: 71891859

Centisome position: 10.18

GC content: 30.35

Gene sequence:

>738_bases
ATGCTTGCCATTATACGTATTATTTTAGTCTTGATATTGTCAATTAATATTTGTATATTTGGTATTATTTATTGTTTATT
AAGACCGCGTCAGTCATACCACACTGCTCTTTTTGGTCGATTGTTCGGAAGCATGGCTCCTATTTTTGGTATTCAACTTA
AAATACGAAATTTATCAAGTAATCAATTACCAAGGCATTGTATATATATTGCGAATCATCAAAATAATTACGATATGATC
ACAGTATCTTGTGTTGTGAAGCCCCGTACAATAATAGTAGGTAAAAAAAATTTATTGTGGATTCCATTTTTTGGGCAACT
ATATTGGTTATGTGGAAATATATTAATTAATCGTAGTAAAAATACTCGGTCTCATAATATTTTAATACAAAAGGCTAAAT
CTGTTAAAACGCACGATATTTCTATTTGGGTTTTTCCGGAAGGTACACGTAGTGCCGGCAGAGGATTGTTACCGTTTAAA
ATTGGTGCGTTTCATGCTGCAATTGCAGCTCGAATACCAATTGTACCTGTTTGTGTTTCTAATATTTCTAATAAAAAAAT
AAAATTAAATCGTTGGTCTAATGGTTTAGTGATTATTGAATTTATGCCTCCTATAGAAACTCAAAAATACGAACCCAATA
AAGTACGTGACATGACTAAATATTGTTATGAGATTATGAAAGTGAAAATTGATTCATTAAATAAAGAGGTAATTGAATAT
GAAACACAGATATCTTGA

Upstream 100 bases:

>100_bases
ATTAAGTATAAGAAATGATATTGTCTGATTAAACATAAACGCAATAATTATATAATTTTTTTTAATAACACGTTCCTAGC
GATATGTTCAAGGAGAAAAT

Downstream 100 bases:

>100_bases
TCATTAAAAACGCATGTATAAAATAATTTTTAACTGTATTGGAGGAGTGGATACGATTTTTAATCGTTTGTTAGTTTGAA
TATGTAAAAATTACGGATAT

Product: 1-acyl-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MLAIIRIILVLILSINICIFGIIYCLLRPRQSYHTALFGRLFGSMAPIFGIQLKIRNLSSNQLPRHCIYIANHQNNYDMI
TVSCVVKPRTIIVGKKNLLWIPFFGQLYWLCGNILINRSKNTRSHNILIQKAKSVKTHDISIWVFPEGTRSAGRGLLPFK
IGAFHAAIAARIPIVPVCVSNISNKKIKLNRWSNGLVIIEFMPPIETQKYEPNKVRDMTKYCYEIMKVKIDSLNKEVIEY
ETQIS

Sequences:

>Translated_245_residues
MLAIIRIILVLILSINICIFGIIYCLLRPRQSYHTALFGRLFGSMAPIFGIQLKIRNLSSNQLPRHCIYIANHQNNYDMI
TVSCVVKPRTIIVGKKNLLWIPFFGQLYWLCGNILINRSKNTRSHNILIQKAKSVKTHDISIWVFPEGTRSAGRGLLPFK
IGAFHAAIAARIPIVPVCVSNISNKKIKLNRWSNGLVIIEFMPPIETQKYEPNKVRDMTKYCYEIMKVKIDSLNKEVIEY
ETQIS
>Mature_245_residues
MLAIIRIILVLILSINICIFGIIYCLLRPRQSYHTALFGRLFGSMAPIFGIQLKIRNLSSNQLPRHCIYIANHQNNYDMI
TVSCVVKPRTIIVGKKNLLWIPFFGQLYWLCGNILINRSKNTRSHNILIQKAKSVKTHDISIWVFPEGTRSAGRGLLPFK
IGAFHAAIAARIPIVPVCVSNISNKKIKLNRWSNGLVIIEFMPPIETQKYEPNKVRDMTKYCYEIMKVKIDSLNKEVIEY
ETQIS

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=200, Percent_Identity=29, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI15100175, Length=200, Percent_Identity=29, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI6041665, Length=235, Percent_Identity=27.2340425531915, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI1789395, Length=242, Percent_Identity=55.7851239669422, Blast_Score=290, Evalue=7e-80,
Organism=Caenorhabditis elegans, GI17568319, Length=208, Percent_Identity=30.2884615384615, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17564032, Length=179, Percent_Identity=28.4916201117318, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320151, Length=241, Percent_Identity=31.5352697095436, Blast_Score=112, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281364648, Length=235, Percent_Identity=32.3404255319149, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24582856, Length=235, Percent_Identity=32.3404255319149, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24582854, Length=235, Percent_Identity=32.3404255319149, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24641614, Length=170, Percent_Identity=33.5294117647059, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24641612, Length=170, Percent_Identity=33.5294117647059, Blast_Score=100, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28100; Mature: 28100

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAIIRIILVLILSINICIFGIIYCLLRPRQSYHTALFGRLFGSMAPIFGIQLKIRNLSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCC
NQLPRHCIYIANHQNNYDMITVSCVVKPRTIIVGKKNLLWIPFFGQLYWLCGNILINRSK
CCCCCEEEEEEECCCCCEEEEEEEEECCEEEEEECCCEEEEEHHHHHHHHHHHHEEECCC
NTRSHNILIQKAKSVKTHDISIWVFPEGTRSAGRGLLPFKIGAFHAAIAARIPIVPVCVS
CCCCCEEEEEECCCCEEEEEEEEEEECCCHHCCCCCCCEEHHHHHHHHHHCCCEEEEECC
NISNKKIKLNRWSNGLVIIEFMPPIETQKYEPNKVRDMTKYCYEIMKVKIDSLNKEVIEY
CCCCCEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ETQIS
HHCCC
>Mature Secondary Structure
MLAIIRIILVLILSINICIFGIIYCLLRPRQSYHTALFGRLFGSMAPIFGIQLKIRNLSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCC
NQLPRHCIYIANHQNNYDMITVSCVVKPRTIIVGKKNLLWIPFFGQLYWLCGNILINRSK
CCCCCEEEEEEECCCCCEEEEEEEEECCEEEEEECCCEEEEEHHHHHHHHHHHHEEECCC
NTRSHNILIQKAKSVKTHDISIWVFPEGTRSAGRGLLPFKIGAFHAAIAARIPIVPVCVS
CCCCCEEEEEECCCCEEEEEEEEEEECCCHHCCCCCCCEEHHHHHHHHHHCCCEEEEECC
NISNKKIKLNRWSNGLVIIEFMPPIETQKYEPNKVRDMTKYCYEIMKVKIDSLNKEVIEY
CCCCCEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ETQIS
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]