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The map label for this gene is ribB [H]

Identifier: 71891855

GI number: 71891855

Start: 79574

End: 80218

Strand: Direct

Name: ribB [H]

Synonym: BPEN_067

Alternate gene names: 71891855

Gene position: 79574-80218 (Clockwise)

Preceding gene: 71891854

Following gene: 71891856

Centisome position: 10.05

GC content: 37.52

Gene sequence:

>645_bases
ATGCACCGGAGGAATGTTTTATCTGAATTTGGATCGCCTGTCGAGCGTGTCCAAAATGCGTTAAAAGCATTGCGCAATGG
ACGGGGTATTTTAGTAATGGATGATGAAAATCGTGAGAATGAAGGTGATATGATATTTGCTGCGGAAAATATGACAGTTG
AACAAATGGCATTAACTATTCGTTATGGCAGTGGGATAGTTTGTTTATGCTTGACAGAGGATCGATGTAAACAGTTAAAT
TTAACAATGATGGTGGAGAATAATAGTAATAGGTATAGAACTGCTTTTACTGTTACTATAGAAGCAGCAAAAGGTGTAAC
TACTGGGGTTTCGGCTGCAGATCGATTAACTACTATTAGAGCTTCTATAGAAGATAGTGCAAAGCCTTCTGACTTAAATC
GTCCTGGACATGTGTTTCCCTTACGCGCTCAAAATGGGGGAGTATTAGCTCGTTTTGGTCATACAGAAGCAGCTGTTGAT
TTAACTTTATTAGCTGGATTAAAGCCATTTGGGGTATTATGTGAAGTAACAAATGAAGATGGAAGTATGGCGCGTATATT
AGAAATAATTGCGTTTGCACGTAGACACAAAATGCCAGTTTTAACTATTTCAGATTTGATAACTTATCGTATTCATATGA
CTTAA

Upstream 100 bases:

>100_bases
AATAGAATATATATATTCTATTTATTAAAATTGTACTTTTTATAGTTTGATCGTATTTTTATTGCAATAAATTATGGTAT
TTAGTGAGGATTTAATTATC

Downstream 100 bases:

>100_bases
TGAAAATAATTGTTCATTAAGTAATAAAGTTTTAAGAATATTTTAAATATATCGCATAAAGAAAATTATATATATTGAAT
ATCATCAATAATGATTGTGT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MHRRNVLSEFGSPVERVQNALKALRNGRGILVMDDENRENEGDMIFAAENMTVEQMALTIRYGSGIVCLCLTEDRCKQLN
LTMMVENNSNRYRTAFTVTIEAAKGVTTGVSAADRLTTIRASIEDSAKPSDLNRPGHVFPLRAQNGGVLARFGHTEAAVD
LTLLAGLKPFGVLCEVTNEDGSMARILEIIAFARRHKMPVLTISDLITYRIHMT

Sequences:

>Translated_214_residues
MHRRNVLSEFGSPVERVQNALKALRNGRGILVMDDENRENEGDMIFAAENMTVEQMALTIRYGSGIVCLCLTEDRCKQLN
LTMMVENNSNRYRTAFTVTIEAAKGVTTGVSAADRLTTIRASIEDSAKPSDLNRPGHVFPLRAQNGGVLARFGHTEAAVD
LTLLAGLKPFGVLCEVTNEDGSMARILEIIAFARRHKMPVLTISDLITYRIHMT
>Mature_214_residues
MHRRNVLSEFGSPVERVQNALKALRNGRGILVMDDENRENEGDMIFAAENMTVEQMALTIRYGSGIVCLCLTEDRCKQLN
LTMMVENNSNRYRTAFTVTIEAAKGVTTGVSAADRLTTIRASIEDSAKPSDLNRPGHVFPLRAQNGGVLARFGHTEAAVD
LTLLAGLKPFGVLCEVTNEDGSMARILEIIAFARRHKMPVLTISDLITYRIHMT

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=207, Percent_Identity=72.9468599033817, Blast_Score=320, Evalue=5e-89,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=42.7860696517413, Blast_Score=178, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 23652; Mature: 23652

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRRNVLSEFGSPVERVQNALKALRNGRGILVMDDENRENEGDMIFAAENMTVEQMALTI
CCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCEEEHEEEEE
RYGSGIVCLCLTEDRCKQLNLTMMVENNSNRYRTAFTVTIEAAKGVTTGVSAADRLTTIR
EECCCEEEEEECHHHHHCCEEEEEEECCCCEEEEEEEEEEECCCCCCCCCCHHHHHHEEE
ASIEDSAKPSDLNRPGHVFPLRAQNGGVLARFGHTEAAVDLTLLAGLKPFGVLCEVTNED
ECCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCHHHHEEEEECCCCCCEEEEEEECCC
GSMARILEIIAFARRHKMPVLTISDLITYRIHMT
CCHHHHHHHHHHHHHCCCCEEECCCEEEEEEEEC
>Mature Secondary Structure
MHRRNVLSEFGSPVERVQNALKALRNGRGILVMDDENRENEGDMIFAAENMTVEQMALTI
CCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCEEEHEEEEE
RYGSGIVCLCLTEDRCKQLNLTMMVENNSNRYRTAFTVTIEAAKGVTTGVSAADRLTTIR
EECCCEEEEEECHHHHHCCEEEEEEECCCCEEEEEEEEEEECCCCCCCCCCHHHHHHEEE
ASIEDSAKPSDLNRPGHVFPLRAQNGGVLARFGHTEAAVDLTLLAGLKPFGVLCEVTNED
ECCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCHHHHEEEEECCCCCCEEEEEEECCC
GSMARILEIIAFARRHKMPVLTISDLITYRIHMT
CCHHHHHHHHHHHHHCCCCEEECCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12886019 [H]