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The map label for this gene is murA

Identifier: 71891838

GI number: 71891838

Start: 57272

End: 58537

Strand: Direct

Name: murA

Synonym: BPEN_047

Alternate gene names: 71891838

Gene position: 57272-58537 (Clockwise)

Preceding gene: 71891837

Following gene: 71891841

Centisome position: 7.23

GC content: 36.89

Gene sequence:

>1266_bases
ATGACAGTGGATAGATTTTATATTCATGGTCCTACTCCTTTAAGTGGTGAAGTGAATATATCAGGTGCTAAAAATTCTGC
ATTACCAATTTTGTTTGCTACGTTATTAACTGAGGAACCGGTAGAAATTTTTAATGTGCCTAAATTAAAAGATATTGATG
TTACTATAAAATTATTAACACAACTTGGAGCAAAAGTGGATCATTGCGATGTAGTTTTTGTAGATACTAGTAGTGTTAAT
ACGTGCTGTGCATCCTATGATCTAGTTAAATCCATGCGTGCTTCCATTTGGGCATTAGGACCATTAGTAGCACGGTTTGG
AGAAGGTAAAATTTGGCTACCTGGAGGATGTTCAATTGGGAAAAGATTAGTAGATTTACATGTTAATGGTTTGGAGCAGT
TGGGGGCAACAATTATCTTAGAAGAAGAGTATGTTACAGCTTCTGTGAATGGACGATTACATGGTGCTCATATTATCATG
GATAAAATCAGTGTTGGAGCTACGGTTACTATCATGAGTGCTGCTGCATTAGCAGAGGGAGTTACTATCATTGATAATGC
TGCTCGCGAACCAGAGATTGTTGATACTGCTAATTTTCTTATTATGTTAGGAACTAATATTAACGGAGCTGGAAGCAATA
GAATTACTATCGAAGGGGCTCAAAAATTAGGAGGGGGAAAGTATTCAATTATGCCAGATCGCATTGAAACTGGTACCTTT
TTAGTTGCTGCCGCTGTTTCACGTACAAATGTAGTATGTTTGGGGTCTCGTCCGGATACGTTGCGTTTTGTGATAAAAAA
ATTACGTGAATCTGGTGCTGATATTAATATGGGTAAAGATTGGATCGGTTTGAACATGCATGGGAAAAGACCTAAAGCTG
TTACTGTATGCACGAAGCCGTATCCAGGGTTTCCTACTGATATGCAAGCACAGTTTACTTTATTAAATATAGTCTCCAAA
GGAAAGGGAAAAATTATAGAGACTATATTTGAAAATAGGTTTATGCACGTACCAGAGCTTGTTCGTATGGGAGCTCGTAT
TAAAATATTAAACAATATGATTGTTTGTCATGGTGTTGATTCATTAATTGGTACTCAAGTTATGGCAACGGACTTGCGGG
CTTCTGCAAGCTTAGTATTGGCTGGTTGTATTGCTGAAGGCTTGACGATAGTGGATTGTGTATATCATATTGATCGAGGA
TATGATCATATTGAAAAAAAGTTAAGAAATATGGGAGCTCATATAAAACGGGTTACTAATAAATAG

Upstream 100 bases:

>100_bases
GCATTTAATCCTCAGGAATGGAACAAAAAGCGTGGATTATGCGGGGTGTGAAGTAATTTTTAAATTAATATGAATTAATT
ATAATGATTGATATTAGGTC

Downstream 100 bases:

>100_bases
TCTTGTTATCAGGTGTGTAACAATTTTTAATTTCGATGATTTTTAGTGATATTATTAGAAGATATATTTCTGAGTTAATT
AATATTATCCCAAATAATCA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTVDRFYIHGPTPLSGEVNISGAKNSALPILFATLLTEEPVEIFNVPKLKDIDVTIKLLTQLGAKVDHCDVVFVDTSSVN
TCCASYDLVKSMRASIWALGPLVARFGEGKIWLPGGCSIGKRLVDLHVNGLEQLGATIILEEEYVTASVNGRLHGAHIIM
DKISVGATVTIMSAAALAEGVTIIDNAAREPEIVDTANFLIMLGTNINGAGSNRITIEGAQKLGGGKYSIMPDRIETGTF
LVAAAVSRTNVVCLGSRPDTLRFVIKKLRESGADINMGKDWIGLNMHGKRPKAVTVCTKPYPGFPTDMQAQFTLLNIVSK
GKGKIIETIFENRFMHVPELVRMGARIKILNNMIVCHGVDSLIGTQVMATDLRASASLVLAGCIAEGLTIVDCVYHIDRG
YDHIEKKLRNMGAHIKRVTNK

Sequences:

>Translated_421_residues
MTVDRFYIHGPTPLSGEVNISGAKNSALPILFATLLTEEPVEIFNVPKLKDIDVTIKLLTQLGAKVDHCDVVFVDTSSVN
TCCASYDLVKSMRASIWALGPLVARFGEGKIWLPGGCSIGKRLVDLHVNGLEQLGATIILEEEYVTASVNGRLHGAHIIM
DKISVGATVTIMSAAALAEGVTIIDNAAREPEIVDTANFLIMLGTNINGAGSNRITIEGAQKLGGGKYSIMPDRIETGTF
LVAAAVSRTNVVCLGSRPDTLRFVIKKLRESGADINMGKDWIGLNMHGKRPKAVTVCTKPYPGFPTDMQAQFTLLNIVSK
GKGKIIETIFENRFMHVPELVRMGARIKILNNMIVCHGVDSLIGTQVMATDLRASASLVLAGCIAEGLTIVDCVYHIDRG
YDHIEKKLRNMGAHIKRVTNK
>Mature_420_residues
TVDRFYIHGPTPLSGEVNISGAKNSALPILFATLLTEEPVEIFNVPKLKDIDVTIKLLTQLGAKVDHCDVVFVDTSSVNT
CCASYDLVKSMRASIWALGPLVARFGEGKIWLPGGCSIGKRLVDLHVNGLEQLGATIILEEEYVTASVNGRLHGAHIIMD
KISVGATVTIMSAAALAEGVTIIDNAAREPEIVDTANFLIMLGTNINGAGSNRITIEGAQKLGGGKYSIMPDRIETGTFL
VAAAVSRTNVVCLGSRPDTLRFVIKKLRESGADINMGKDWIGLNMHGKRPKAVTVCTKPYPGFPTDMQAQFTLLNIVSKG
KGKIIETIFENRFMHVPELVRMGARIKILNNMIVCHGVDSLIGTQVMATDLRASASLVLAGCIAEGLTIVDCVYHIDRGY
DHIEKKLRNMGAHIKRVTNK

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=70.1670644391408, Blast_Score=620, Evalue=1e-179,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_BLOPB (Q493Y9)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277567.1
- ProteinModelPortal:   Q493Y9
- SMR:   Q493Y9
- STRING:   Q493Y9
- GeneID:   3562894
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_047
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   CBLO291272:BPEN_047-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45491; Mature: 45360

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVDRFYIHGPTPLSGEVNISGAKNSALPILFATLLTEEPVEIFNVPKLKDIDVTIKLLT
CCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHH
QLGAKVDHCDVVFVDTSSVNTCCASYDLVKSMRASIWALGPLVARFGEGKIWLPGGCSIG
HHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHH
KRLVDLHVNGLEQLGATIILEEEYVTASVNGRLHGAHIIMDKISVGATVTIMSAAALAEG
HEEEEEECCCHHHCCCEEEEECCEEEEEECCEEEEEEEEEEECCCCEEEEHHHHHHHHCC
VTIIDNAAREPEIVDTANFLIMLGTNINGAGSNRITIEGAQKLGGGKYSIMPDRIETGTF
CEEEECCCCCCCEEECCCEEEEEECCCCCCCCCEEEEEEHHHCCCCEEEECCCCCCCCCE
LVAAAVSRTNVVCLGSRPDTLRFVIKKLRESGADINMGKDWIGLNMHGKRPKAVTVCTKP
EEEEEECCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCEEEEECCC
YPGFPTDMQAQFTLLNIVSKGKGKIIETIFENRFMHVPELVRMGARIKILNNMIVCHGVD
CCCCCCCCCHHHHEEEHHHCCCCHHHHHHHHCCCCCCHHHHHCCCEEEEECCEEEEECCH
SLIGTQVMATDLRASASLVLAGCIAEGLTIVDCVYHIDRGYDHIEKKLRNMGAHIKRVTN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
K
C
>Mature Secondary Structure 
TVDRFYIHGPTPLSGEVNISGAKNSALPILFATLLTEEPVEIFNVPKLKDIDVTIKLLT
CCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHH
QLGAKVDHCDVVFVDTSSVNTCCASYDLVKSMRASIWALGPLVARFGEGKIWLPGGCSIG
HHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHH
KRLVDLHVNGLEQLGATIILEEEYVTASVNGRLHGAHIIMDKISVGATVTIMSAAALAEG
HEEEEEECCCHHHCCCEEEEECCEEEEEECCEEEEEEEEEEECCCCEEEEHHHHHHHHCC
VTIIDNAAREPEIVDTANFLIMLGTNINGAGSNRITIEGAQKLGGGKYSIMPDRIETGTF
CEEEECCCCCCCEEECCCEEEEEECCCCCCCCCEEEEEEHHHCCCCEEEECCCCCCCCCE
LVAAAVSRTNVVCLGSRPDTLRFVIKKLRESGADINMGKDWIGLNMHGKRPKAVTVCTKP
EEEEEECCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCEEEEECCC
YPGFPTDMQAQFTLLNIVSKGKGKIIETIFENRFMHVPELVRMGARIKILNNMIVCHGVD
CCCCCCCCCHHHHEEEHHHCCCCHHHHHHHHCCCCCCHHHHHCCCEEEEECCEEEEECCH
SLIGTQVMATDLRASASLVLAGCIAEGLTIVDCVYHIDRGYDHIEKKLRNMGAHIKRVTN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA