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The map label for this gene is yjcE [H]

Identifier: 71891821

GI number: 71891821

Start: 35067

End: 36710

Strand: Direct

Name: yjcE [H]

Synonym: BPEN_029

Alternate gene names: 71891821

Gene position: 35067-36710 (Clockwise)

Preceding gene: 71891820

Following gene: 71891822

Centisome position: 4.43

GC content: 35.4

Gene sequence:

>1644_bases
ATGGAGATTTTTTTTACGATTCTGATTCTTACTTTAGCTGTCTCTATTTCAGGAGTTATAACACGAATTTTGCCGTTTCA
AATGCCATTGCCTCTCATGCAAATTGTATTAGGGGCTTTATTAGCTTGGCCTAGATTTGGATTACATGTAGATTTTAATC
CTGAGCTATTTTTATTGCTTTTTATCCCCCCGTTATTATTCTCCGATGGTTGGAAAACCCCAATGCGTGAGTTTTTACGT
CATGGAGGTGAAATTGTTATATTAGCATTGGTGTTGGTAATTATTACTGTGGTTGGTATTGGATATTTAATTCATTGGAT
GATACCAGACATGCCTCTTGTAGCAGCGTTAGCACTGGCAGCGGTTTTATCTCCAACTGATGCAGTAGCGCTTTCAGGTA
TCGTAGGAGAGGGACGTATTTCTAAAAAGCTTATGGACATTCTTCAAGGAGAAGCTTTGATGAATGATGCGTCAGGATTA
GTATCTCTTAAATTTGCTATTTCAGTAGCTATGGGCACTATGGTTTTCAGTGTGAGCGGAGCTTCTATAGAATTTATTAA
AATATCTATGGGTGGTTTATTAACGGGGATAGCTGTTACTTGGGGATATAGTAAATCATTAAGGTTTATTACTCATTGGA
GTGGTGGTGATCCTGCAACTCAAACAATACTTCTTTTATTGTTACCTTTTGCGGCATATTTAGTTGCTGAGCATATTGGA
GTATCTGGAATATTATCGTCAGTTGCCTCAGGAATGACTATTGGCCAATCAGGAATAATCCGTAATGCCCCGTTAGCTAT
GCGTTTGAGGGGAAATAGTGTTTGGACAATGTTAGAGTTTGTGTTTAATGGTATGGTGTTTATTATGCTGGGATTGCAAT
TACCAGATATTTTATCGACTTCTATTTCACAAGCAGCAATGGATCCAACTACTAAAACATGGATGTTATTTGTATATGTA
ATTCTTATTTATTTCGCATTAATGATACTTAGATTTGGATGGTTGTGGTTAATGAAAAATATAAGTTTATATTTTATGAC
TAAACGTCCAATGGTATTTAGCGAATATAGTGTACGAGAAATTTTAATTGCTTCTTTTGCTGGAGTACGGGGTGCTATTA
CATTAGCAGGAGTACTTTCAATACCACTTTTTTTAAGAGATGGATCAGCTTTTCCGTTTCGTTATCAATTAGTTTTTATT
GCCACTGGTGTTATTTTATTCTCTTTATTATGTGGTGTAATTGTTCTTCCGTGGTTGTTGCAGGGAATTATAGTATCTGA
TAAATTATTACAACGAAAAGAAGAGCGTATGGCACGGGCTATAGCAGCAGAAGTAGCTATTGAAAGTTTATATAAACTAG
AAGAACGGTTAATGCATAGCCAAGAAGAAAATATTGATAGTCAAATTATTAATGAGGTAAGCGCACGTGTTATAGGTAAT
TTACGCCGTCGTATAGACGGAAATAATGATGTAAATTCTATGTTAACTGAAGAGTTAGAGAGACGGATGAGGTTAAACGC
ATTACGTGCTGAAAGAGGAGAATATTATCATTTACGTGCGCAACAAAAAATTAGTAATGAAACGTTAACTAAATTGTTAC
GCGACTTAGATTTTTTAGAAGCTTTATTAGCAGAGAATGAATAA

Upstream 100 bases:

>100_bases
GGTGTGCCATGCTTATTCACAATATGAAGTACATATAAAAAATAAATACTATATTTGTAGAAAAATACTTATTTTTTTGG
ATATGATTGAGATTTAAAGT

Downstream 100 bases:

>100_bases
TATTACCTTATTTAATAAGGGTGATTGCAATTTTTATAAATATTTATATCATTAATGCTGAGAAATTTTAAGGAATTAAC
AGGAATTGATGTAAAGATCA

Product: CPA1 family Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MEIFFTILILTLAVSISGVITRILPFQMPLPLMQIVLGALLAWPRFGLHVDFNPELFLLLFIPPLLFSDGWKTPMREFLR
HGGEIVILALVLVIITVVGIGYLIHWMIPDMPLVAALALAAVLSPTDAVALSGIVGEGRISKKLMDILQGEALMNDASGL
VSLKFAISVAMGTMVFSVSGASIEFIKISMGGLLTGIAVTWGYSKSLRFITHWSGGDPATQTILLLLLPFAAYLVAEHIG
VSGILSSVASGMTIGQSGIIRNAPLAMRLRGNSVWTMLEFVFNGMVFIMLGLQLPDILSTSISQAAMDPTTKTWMLFVYV
ILIYFALMILRFGWLWLMKNISLYFMTKRPMVFSEYSVREILIASFAGVRGAITLAGVLSIPLFLRDGSAFPFRYQLVFI
ATGVILFSLLCGVIVLPWLLQGIIVSDKLLQRKEERMARAIAAEVAIESLYKLEERLMHSQEENIDSQIINEVSARVIGN
LRRRIDGNNDVNSMLTEELERRMRLNALRAERGEYYHLRAQQKISNETLTKLLRDLDFLEALLAENE

Sequences:

>Translated_547_residues
MEIFFTILILTLAVSISGVITRILPFQMPLPLMQIVLGALLAWPRFGLHVDFNPELFLLLFIPPLLFSDGWKTPMREFLR
HGGEIVILALVLVIITVVGIGYLIHWMIPDMPLVAALALAAVLSPTDAVALSGIVGEGRISKKLMDILQGEALMNDASGL
VSLKFAISVAMGTMVFSVSGASIEFIKISMGGLLTGIAVTWGYSKSLRFITHWSGGDPATQTILLLLLPFAAYLVAEHIG
VSGILSSVASGMTIGQSGIIRNAPLAMRLRGNSVWTMLEFVFNGMVFIMLGLQLPDILSTSISQAAMDPTTKTWMLFVYV
ILIYFALMILRFGWLWLMKNISLYFMTKRPMVFSEYSVREILIASFAGVRGAITLAGVLSIPLFLRDGSAFPFRYQLVFI
ATGVILFSLLCGVIVLPWLLQGIIVSDKLLQRKEERMARAIAAEVAIESLYKLEERLMHSQEENIDSQIINEVSARVIGN
LRRRIDGNNDVNSMLTEELERRMRLNALRAERGEYYHLRAQQKISNETLTKLLRDLDFLEALLAENE
>Mature_547_residues
MEIFFTILILTLAVSISGVITRILPFQMPLPLMQIVLGALLAWPRFGLHVDFNPELFLLLFIPPLLFSDGWKTPMREFLR
HGGEIVILALVLVIITVVGIGYLIHWMIPDMPLVAALALAAVLSPTDAVALSGIVGEGRISKKLMDILQGEALMNDASGL
VSLKFAISVAMGTMVFSVSGASIEFIKISMGGLLTGIAVTWGYSKSLRFITHWSGGDPATQTILLLLLPFAAYLVAEHIG
VSGILSSVASGMTIGQSGIIRNAPLAMRLRGNSVWTMLEFVFNGMVFIMLGLQLPDILSTSISQAAMDPTTKTWMLFVYV
ILIYFALMILRFGWLWLMKNISLYFMTKRPMVFSEYSVREILIASFAGVRGAITLAGVLSIPLFLRDGSAFPFRYQLVFI
ATGVILFSLLCGVIVLPWLLQGIIVSDKLLQRKEERMARAIAAEVAIESLYKLEERLMHSQEENIDSQIINEVSARVIGN
LRRRIDGNNDVNSMLTEELERRMRLNALRAERGEYYHLRAQQKISNETLTKLLRDLDFLEALLAENE

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI148727259, Length=467, Percent_Identity=24.8394004282655, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI15529998, Length=430, Percent_Identity=23.953488372093, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI14211919, Length=377, Percent_Identity=23.342175066313, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI27734935, Length=462, Percent_Identity=22.2943722943723, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI294997330, Length=381, Percent_Identity=23.6220472440945, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI110227626, Length=381, Percent_Identity=23.6220472440945, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI5454070, Length=381, Percent_Identity=23.6220472440945, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4759144, Length=355, Percent_Identity=24.5070422535211, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI41872703, Length=484, Percent_Identity=23.9669421487603, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI194239733, Length=408, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1790501, Length=548, Percent_Identity=69.7080291970803, Blast_Score=761, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980847, Length=414, Percent_Identity=25.1207729468599, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25150332, Length=382, Percent_Identity=23.2984293193717, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71987535, Length=509, Percent_Identity=25.147347740668, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71987537, Length=509, Percent_Identity=25.147347740668, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71999819, Length=466, Percent_Identity=24.0343347639485, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71990932, Length=421, Percent_Identity=23.0403800475059, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71999821, Length=466, Percent_Identity=24.0343347639485, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71999817, Length=466, Percent_Identity=24.0343347639485, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71990924, Length=421, Percent_Identity=24.2280285035629, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71992101, Length=337, Percent_Identity=23.4421364985163, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71992107, Length=337, Percent_Identity=23.4421364985163, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320663, Length=258, Percent_Identity=25.968992248062, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221510734, Length=466, Percent_Identity=22.3175965665236, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221510738, Length=424, Percent_Identity=22.877358490566, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 60759; Mature: 60759

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFFTILILTLAVSISGVITRILPFQMPLPLMQIVLGALLAWPRFGLHVDFNPELFLLL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEHHH
FIPPLLFSDGWKTPMREFLRHGGEIVILALVLVIITVVGIGYLIHWMIPDMPLVAALALA
HHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AVLSPTDAVALSGIVGEGRISKKLMDILQGEALMNDASGLVSLKFAISVAMGTMVFSVSG
HHHCCCHHHHHHCCCCCCHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHEEECC
ASIEFIKISMGGLLTGIAVTWGYSKSLRFITHWSGGDPATQTILLLLLPFAAYLVAEHIG
CEEEEEEEEHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
VSGILSSVASGMTIGQSGIIRNAPLAMRLRGNSVWTMLEFVFNGMVFIMLGLQLPDILST
HHHHHHHHHCCCEECCCCCEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SISQAAMDPTTKTWMLFVYVILIYFALMILRFGWLWLMKNISLYFMTKRPMVFSEYSVRE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEECHHHHHH
ILIASFAGVRGAITLAGVLSIPLFLRDGSAFPFRYQLVFIATGVILFSLLCGVIVLPWLL
HHHHHHHCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGIIVSDKLLQRKEERMARAIAAEVAIESLYKLEERLMHSQEENIDSQIINEVSARVIGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LRRRIDGNNDVNSMLTEELERRMRLNALRAERGEYYHLRAQQKISNETLTKLLRDLDFLE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ALLAENE
HHHCCCC
>Mature Secondary Structure
MEIFFTILILTLAVSISGVITRILPFQMPLPLMQIVLGALLAWPRFGLHVDFNPELFLLL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEHHH
FIPPLLFSDGWKTPMREFLRHGGEIVILALVLVIITVVGIGYLIHWMIPDMPLVAALALA
HHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AVLSPTDAVALSGIVGEGRISKKLMDILQGEALMNDASGLVSLKFAISVAMGTMVFSVSG
HHHCCCHHHHHHCCCCCCHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHEEECC
ASIEFIKISMGGLLTGIAVTWGYSKSLRFITHWSGGDPATQTILLLLLPFAAYLVAEHIG
CEEEEEEEEHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
VSGILSSVASGMTIGQSGIIRNAPLAMRLRGNSVWTMLEFVFNGMVFIMLGLQLPDILST
HHHHHHHHHCCCEECCCCCEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SISQAAMDPTTKTWMLFVYVILIYFALMILRFGWLWLMKNISLYFMTKRPMVFSEYSVRE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEECHHHHHH
ILIASFAGVRGAITLAGVLSIPLFLRDGSAFPFRYQLVFIATGVILFSLLCGVIVLPWLL
HHHHHHHCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGIIVSDKLLQRKEERMARAIAAEVAIESLYKLEERLMHSQEENIDSQIINEVSARVIGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LRRRIDGNNDVNSMLTEELERRMRLNALRAERGEYYHLRAQQKISNETLTKLLRDLDFLE
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
ALLAENE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]