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The map label for this gene is prlC [H]

Identifier: 71891815

GI number: 71891815

Start: 25566

End: 27638

Strand: Direct

Name: prlC [H]

Synonym: BPEN_023

Alternate gene names: 71891815

Gene position: 25566-27638 (Clockwise)

Preceding gene: 71891813

Following gene: 71891817

Centisome position: 3.23

GC content: 31.02

Gene sequence:

>2073_bases
ATGGATAATAATCCGCTATTAAATTATTCTATATTCCCTCCATTTTCTTCTATTAAGATAAATCATGTAAAAGAAGCTGT
ACAAAAGATTTTGACTAATTGTTATAATACGGTAGATCAGATTGTATCTGAAAAACGTATAACTTGGGATACGTTATATT
ATCCGTTGATGATTGCAGAAAATGAATTGCAACGCATTTGGTCTCCGATAACACATTTAAATTCTGTACAGCATAATTTA
GCATTACGTAAGGTTTATGAAGAAAGTCTGTCATTTATTTCTGAATATAGGAATTGGATCAATCAACATGATGGATTGTA
TAAATCTTATCAATCATTACAACGTGGAGATTCCGGTCAAAAGTTGAGCATAATACAGAAAAAAGTATTAAATAATATTT
TACATAATTTTAAGTTATCGGGGATTTATTTATCTCCCCAGAAAAAAAAAATATATGCATATATAACTTCTAGATTGTCC
CGATTAAGGTCAAATTATGCTAATAATGTATTTGATGCAACGCTAGGTTGGAGCAAGTTAATTACTGAAAAAAAGTTATT
ATCTGGGATACCAGATCATGCATTGGAGATTGCTCGTTTAGCAGCACAAGCTCGTGGAGAAAAAGGATGGTTATTTACAC
TGCAATACCCTAGTTATTCTTCAGTTCTTTTGTATTGTGATACCAAAGAACTTAGAGAAGAGTTATATTGGGCTTTTAAT
ACTCGTGCTTCTGACCAAGGACCTAATAGTGGAAAATGGGATAATACTTTAGTAATGGATGAAATTCTTGCATTACGCTA
TGAGTTAGCAAAAATATTAGGATTTAGAACTTATTTTGAAAAATCTTTATCAAAAAGAATGGTACAGAGCCCAAAAAAAG
TATTTAATTTTCTTATGAATTTATCTATCCAGATACGTTCTTCTGAATATAAGGAATTTTTAGAAATACAAAATTTTTCT
AAAAAAAACAGTTCTTGTATATCTTTAAATCCATGGGATATTGCATATTATAGAGAGAAACAGAAACAATATCTTTTTTC
TATTAAAAATGAAGAACTATGTTGTTATTTTCCTGAAAAAACAGTACTTCATGGAATGTTTTCAGTAGTGAATCGTATTT
ACGGAATTACTATTAAAGAGCGTTCTAATGTAGAAACATGGCATTCTGATGTACGATTTTTTGATATTTTTGATGGAGAA
GATAGATGGATGGGAGGATTTTATTTAGATATGTATCTTAGAGATGATAAACGTGAGGGTGCTTGGATGGATGAGTTAGT
AGGTAAGATGTATCGAAATGATACTATTAGCCAAAAACCTATCGCATACTTAACTTGTAACTTTAATTGTTCAGAGAAGC
AAAAATCATCATGTTTGTTAACGCATCATGATGTGATGACTTTGTTTCATGAATTTGGCCATGTACTACATCATATCATG
ACACGTATTGATATTCCGGAAATATCTGGAGTTAATGGAGTACCTTGGGATGCATTAGAATTACCTAGTCAACTTATGGA
AAAATTTTGTTGGGATCCCGATGTATTACAATTAATTTCTATGCATTATCGAACAAAAGAACCGCTACCTGGTTATATCA
TAAATAATTTATTAAAAACAAAAACATATCAATCATCATCTTATCTTTTACGTCAAGTGATATATGGGTTATTTGATTTA
CGAATACATCATGAATATATACCAGGAGAAAAGAGGAGTGCATTAAAAATATTTAACGAAGTAATAAAACAAGTATCAAC
GTGTCATCTTTCAATGGATTGGGATCGTTTCCCTAACTCTTTTCTGCATGCTTTTTCTGATGATTATTCTGCGGGGTATT
ATAGCTATTTATGGGCAGATATGTTAGCATCCAACGTTTGGTGTCGTTTTCAAGAATTAGGTATTCTTAATTCAAAAATA
GGGAAATTATTTCTTAATGACATCCTTGCGTTGGGAGGTACTATCGATTTGAAAAAATGTCTGGTAAAATTTTGTACACA
AACTATGACAGTAGAACCTATGCTAAAGTATTACGGGATCCCTGTTTCTGTTGACCATTCCATGCCAATATAA

Upstream 100 bases:

>100_bases
CATCAGATATACATGTGTCCCGTTTAGATATATAAACTCGATACAACGGAAGATTTCAAATTTGGCTACATAATAGTTAC
TAATTTTTAGGTTTTATTAT

Downstream 100 bases:

>100_bases
TATGCACAAATTATTAAAAATATTATTTTATATGTGAATCATTCTTCAATTAAGAATGATAGATTGATGTTTTTTAATTT
TTATTATAGACAAAGAATGT

Product: oligopeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MDNNPLLNYSIFPPFSSIKINHVKEAVQKILTNCYNTVDQIVSEKRITWDTLYYPLMIAENELQRIWSPITHLNSVQHNL
ALRKVYEESLSFISEYRNWINQHDGLYKSYQSLQRGDSGQKLSIIQKKVLNNILHNFKLSGIYLSPQKKKIYAYITSRLS
RLRSNYANNVFDATLGWSKLITEKKLLSGIPDHALEIARLAAQARGEKGWLFTLQYPSYSSVLLYCDTKELREELYWAFN
TRASDQGPNSGKWDNTLVMDEILALRYELAKILGFRTYFEKSLSKRMVQSPKKVFNFLMNLSIQIRSSEYKEFLEIQNFS
KKNSSCISLNPWDIAYYREKQKQYLFSIKNEELCCYFPEKTVLHGMFSVVNRIYGITIKERSNVETWHSDVRFFDIFDGE
DRWMGGFYLDMYLRDDKREGAWMDELVGKMYRNDTISQKPIAYLTCNFNCSEKQKSSCLLTHHDVMTLFHEFGHVLHHIM
TRIDIPEISGVNGVPWDALELPSQLMEKFCWDPDVLQLISMHYRTKEPLPGYIINNLLKTKTYQSSSYLLRQVIYGLFDL
RIHHEYIPGEKRSALKIFNEVIKQVSTCHLSMDWDRFPNSFLHAFSDDYSAGYYSYLWADMLASNVWCRFQELGILNSKI
GKLFLNDILALGGTIDLKKCLVKFCTQTMTVEPMLKYYGIPVSVDHSMPI

Sequences:

>Translated_690_residues
MDNNPLLNYSIFPPFSSIKINHVKEAVQKILTNCYNTVDQIVSEKRITWDTLYYPLMIAENELQRIWSPITHLNSVQHNL
ALRKVYEESLSFISEYRNWINQHDGLYKSYQSLQRGDSGQKLSIIQKKVLNNILHNFKLSGIYLSPQKKKIYAYITSRLS
RLRSNYANNVFDATLGWSKLITEKKLLSGIPDHALEIARLAAQARGEKGWLFTLQYPSYSSVLLYCDTKELREELYWAFN
TRASDQGPNSGKWDNTLVMDEILALRYELAKILGFRTYFEKSLSKRMVQSPKKVFNFLMNLSIQIRSSEYKEFLEIQNFS
KKNSSCISLNPWDIAYYREKQKQYLFSIKNEELCCYFPEKTVLHGMFSVVNRIYGITIKERSNVETWHSDVRFFDIFDGE
DRWMGGFYLDMYLRDDKREGAWMDELVGKMYRNDTISQKPIAYLTCNFNCSEKQKSSCLLTHHDVMTLFHEFGHVLHHIM
TRIDIPEISGVNGVPWDALELPSQLMEKFCWDPDVLQLISMHYRTKEPLPGYIINNLLKTKTYQSSSYLLRQVIYGLFDL
RIHHEYIPGEKRSALKIFNEVIKQVSTCHLSMDWDRFPNSFLHAFSDDYSAGYYSYLWADMLASNVWCRFQELGILNSKI
GKLFLNDILALGGTIDLKKCLVKFCTQTMTVEPMLKYYGIPVSVDHSMPI
>Mature_690_residues
MDNNPLLNYSIFPPFSSIKINHVKEAVQKILTNCYNTVDQIVSEKRITWDTLYYPLMIAENELQRIWSPITHLNSVQHNL
ALRKVYEESLSFISEYRNWINQHDGLYKSYQSLQRGDSGQKLSIIQKKVLNNILHNFKLSGIYLSPQKKKIYAYITSRLS
RLRSNYANNVFDATLGWSKLITEKKLLSGIPDHALEIARLAAQARGEKGWLFTLQYPSYSSVLLYCDTKELREELYWAFN
TRASDQGPNSGKWDNTLVMDEILALRYELAKILGFRTYFEKSLSKRMVQSPKKVFNFLMNLSIQIRSSEYKEFLEIQNFS
KKNSSCISLNPWDIAYYREKQKQYLFSIKNEELCCYFPEKTVLHGMFSVVNRIYGITIKERSNVETWHSDVRFFDIFDGE
DRWMGGFYLDMYLRDDKREGAWMDELVGKMYRNDTISQKPIAYLTCNFNCSEKQKSSCLLTHHDVMTLFHEFGHVLHHIM
TRIDIPEISGVNGVPWDALELPSQLMEKFCWDPDVLQLISMHYRTKEPLPGYIINNLLKTKTYQSSSYLLRQVIYGLFDL
RIHHEYIPGEKRSALKIFNEVIKQVSTCHLSMDWDRFPNSFLHAFSDDYSAGYYSYLWADMLASNVWCRFQELGILNSKI
GKLFLNDILALGGTIDLKKCLVKFCTQTMTVEPMLKYYGIPVSVDHSMPI

Specific function: May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4) [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=611, Percent_Identity=26.0229132569558, Blast_Score=215, Evalue=9e-56,
Organism=Homo sapiens, GI14149738, Length=599, Percent_Identity=26.8781302170284, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI156105687, Length=590, Percent_Identity=26.271186440678, Blast_Score=165, Evalue=1e-40,
Organism=Escherichia coli, GI1789913, Length=678, Percent_Identity=48.6725663716814, Blast_Score=695, Evalue=0.0,
Organism=Escherichia coli, GI1787819, Length=691, Percent_Identity=25.7597684515195, Blast_Score=221, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI32565901, Length=571, Percent_Identity=21.7162872154116, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71999758, Length=584, Percent_Identity=22.7739726027397, Blast_Score=103, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319793, Length=688, Percent_Identity=26.453488372093, Blast_Score=234, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6322715, Length=636, Percent_Identity=24.0566037735849, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356111, Length=690, Percent_Identity=25.6521739130435, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI20129717, Length=411, Percent_Identity=25.0608272506083, Blast_Score=140, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.24.70 [H]

Molecular weight: Translated: 80795; Mature: 80795

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNPLLNYSIFPPFSSIKINHVKEAVQKILTNCYNTVDQIVSEKRITWDTLYYPLMIAE
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCH
NELQRIWSPITHLNSVQHNLALRKVYEESLSFISEYRNWINQHDGLYKSYQSLQRGDSGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
KLSIIQKKVLNNILHNFKLSGIYLSPQKKKIYAYITSRLSRLRSNYANNVFDATLGWSKL
HHHHHHHHHHHHHHHHCEECEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHH
ITEKKLLSGIPDHALEIARLAAQARGEKGWLFTLQYPSYSSVLLYCDTKELREELYWAFN
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECHHHHHHHHHHHHC
TRASDQGPNSGKWDNTLVMDEILALRYELAKILGFRTYFEKSLSKRMVQSPKKVFNFLMN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHC
LSIQIRSSEYKEFLEIQNFSKKNSSCISLNPWDIAYYREKQKQYLFSIKNEELCCYFPEK
CEEEEECHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCHH
TVLHGMFSVVNRIYGITIKERSNVETWHSDVRFFDIFDGEDRWMGGFYLDMYLRDDKREG
HHHHHHHHHHHHHHCEEEECCCCCHHHHCCCEEEEEECCCCCCCCCEEEEEEEECCCCCC
AWMDELVGKMYRNDTISQKPIAYLTCNFNCSEKQKSSCLLTHHDVMTLFHEFGHVLHHIM
CCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHCCCEEEHHHHHHHHHHHHHHHHHHHH
TRIDIPEISGVNGVPWDALELPSQLMEKFCWDPDVLQLISMHYRTKEPLPGYIINNLLKT
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
KTYQSSSYLLRQVIYGLFDLRIHHEYIPGEKRSALKIFNEVIKQVSTCHLSMDWDRFPNS
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCHHHCCHH
FLHAFSDDYSAGYYSYLWADMLASNVWCRFQELGILNSKIGKLFLNDILALGGTIDLKKC
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHH
LVKFCTQTMTVEPMLKYYGIPVSVDHSMPI
HHHHHHHHCCHHHHHHHCCCCEECCCCCCC
>Mature Secondary Structure
MDNNPLLNYSIFPPFSSIKINHVKEAVQKILTNCYNTVDQIVSEKRITWDTLYYPLMIAE
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCH
NELQRIWSPITHLNSVQHNLALRKVYEESLSFISEYRNWINQHDGLYKSYQSLQRGDSGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
KLSIIQKKVLNNILHNFKLSGIYLSPQKKKIYAYITSRLSRLRSNYANNVFDATLGWSKL
HHHHHHHHHHHHHHHHCEECEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHH
ITEKKLLSGIPDHALEIARLAAQARGEKGWLFTLQYPSYSSVLLYCDTKELREELYWAFN
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECHHHHHHHHHHHHC
TRASDQGPNSGKWDNTLVMDEILALRYELAKILGFRTYFEKSLSKRMVQSPKKVFNFLMN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHC
LSIQIRSSEYKEFLEIQNFSKKNSSCISLNPWDIAYYREKQKQYLFSIKNEELCCYFPEK
CEEEEECHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCHH
TVLHGMFSVVNRIYGITIKERSNVETWHSDVRFFDIFDGEDRWMGGFYLDMYLRDDKREG
HHHHHHHHHHHHHHCEEEECCCCCHHHHCCCEEEEEECCCCCCCCCEEEEEEEECCCCCC
AWMDELVGKMYRNDTISQKPIAYLTCNFNCSEKQKSSCLLTHHDVMTLFHEFGHVLHHIM
CCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHCCCEEEHHHHHHHHHHHHHHHHHHHH
TRIDIPEISGVNGVPWDALELPSQLMEKFCWDPDVLQLISMHYRTKEPLPGYIINNLLKT
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
KTYQSSSYLLRQVIYGLFDLRIHHEYIPGEKRSALKIFNEVIKQVSTCHLSMDWDRFPNS
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEECCHHHCCHH
FLHAFSDDYSAGYYSYLWADMLASNVWCRFQELGILNSKIGKLFLNDILALGGTIDLKKC
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHH
LVKFCTQTMTVEPMLKYYGIPVSVDHSMPI
HHHHHHHHCCHHHHHHHCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1325967; 8366062; 8041620; 9278503 [H]