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The map label for this gene is sigM [H]

Identifier: 68537187

GI number: 68537187

Start: 2450979

End: 2451596

Strand: Direct

Name: sigM [H]

Synonym: jk2092

Alternate gene names: 68537187

Gene position: 2450979-2451596 (Clockwise)

Preceding gene: 68537186

Following gene: 68537188

Centisome position: 99.53

GC content: 61.97

Gene sequence:

>618_bases
ATGATGCTGGGGGCGTCACAAAATACAAAGAACGACACACGGCCAGCGCAACAAACGGACCATGAACTGCTGCGCGGCCA
CAACGATGGGCAACCCGGCGCGTTTCGCGAGCTGATCGACCGCCACCAGCGCACATTGTGGTGGGCAGTGCGGCGAGTCA
ACGTGCCTGAGGGCCACCAAATGGACGTTTACCAGGAAGGACTGCTGCGCGTGCACCGTTTCGCAGCGCGCTTCAACGGA
GATCGCTCCGCCAGCGTAAGCACCTGGATGGCCACCATTATGCGCAACGCGGCGCTTTCATATATGCAGCGCTACAGTCG
CGAGGCACAACCGGGACGCGAAGACTTCAACGAATGCACGCGAACCTTGCCCGCGCGGGGAATGCGGGAGGAAGCCACCG
TCGCCCGACTGGATGTCCACCGCAGCCTGCGACGACTCTCGCCCGAAATGCGGGACGTGATGGTGCTGACGGAGATTCGA
GGCCTAAGCGAGGCAAAAGCCGCAGCGCAACTGGGGATCCCCGTTGGCACTGTGAAGTCGCGGAAGAACCGGGCAAAGCG
CATGATGTACGAACACCTCGGTGGGGCAGAGGAATACGGGATGGCCGTGGCCGGTTAA

Upstream 100 bases:

>100_bases
TCCACAGGTCCAAGACTAAAGACCCACAACCTGGCCCACCGATGAATAAAGTGTGAGGCAAGGGGGGCGGCATGGCTCCC
GACGACACACTAGGGGGAAG

Downstream 100 bases:

>100_bases
ACTGGAGTGAACAACATCTCCGACCTCAAAGGATAGATATGAACCAGCCATTCCTGCAGGCCAGCGGTATTCTCAACAAT
GATTCGAAGGGTGCCGCGGA

Product: ECF family RNA polymerasesigma factor M

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MMLGASQNTKNDTRPAQQTDHELLRGHNDGQPGAFRELIDRHQRTLWWAVRRVNVPEGHQMDVYQEGLLRVHRFAARFNG
DRSASVSTWMATIMRNAALSYMQRYSREAQPGREDFNECTRTLPARGMREEATVARLDVHRSLRRLSPEMRDVMVLTEIR
GLSEAKAAAQLGIPVGTVKSRKNRAKRMMYEHLGGAEEYGMAVAG

Sequences:

>Translated_205_residues
MMLGASQNTKNDTRPAQQTDHELLRGHNDGQPGAFRELIDRHQRTLWWAVRRVNVPEGHQMDVYQEGLLRVHRFAARFNG
DRSASVSTWMATIMRNAALSYMQRYSREAQPGREDFNECTRTLPARGMREEATVARLDVHRSLRRLSPEMRDVMVLTEIR
GLSEAKAAAQLGIPVGTVKSRKNRAKRMMYEHLGGAEEYGMAVAG
>Mature_205_residues
MMLGASQNTKNDTRPAQQTDHELLRGHNDGQPGAFRELIDRHQRTLWWAVRRVNVPEGHQMDVYQEGLLRVHRFAARFNG
DRSASVSTWMATIMRNAALSYMQRYSREAQPGREDFNECTRTLPARGMREEATVARLDVHRSLRRLSPEMRDVMVLTEIR
GLSEAKAAAQLGIPVGTVKSRKNRAKRMMYEHLGGAEEYGMAVAG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=178, Percent_Identity=30.3370786516854, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 23335; Mature: 23335

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLGASQNTKNDTRPAQQTDHELLRGHNDGQPGAFRELIDRHQRTLWWAVRRVNVPEGHQ
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MDVYQEGLLRVHRFAARFNGDRSASVSTWMATIMRNAALSYMQRYSREAQPGREDFNECT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RTLPARGMREEATVARLDVHRSLRRLSPEMRDVMVLTEIRGLSEAKAAAQLGIPVGTVKS
HHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHH
RKNRAKRMMYEHLGGAEEYGMAVAG
HHHHHHHHHHHHCCCHHHHCCCCCC
>Mature Secondary Structure
MMLGASQNTKNDTRPAQQTDHELLRGHNDGQPGAFRELIDRHQRTLWWAVRRVNVPEGHQ
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MDVYQEGLLRVHRFAARFNGDRSASVSTWMATIMRNAALSYMQRYSREAQPGREDFNECT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RTLPARGMREEATVARLDVHRSLRRLSPEMRDVMVLTEIRGLSEAKAAAQLGIPVGTVKS
HHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHH
RKNRAKRMMYEHLGGAEEYGMAVAG
HHHHHHHHHHHHCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]