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The map label for this gene is trxB [H]

Identifier: 68537188

GI number: 68537188

Start: 2451635

End: 2452669

Strand: Direct

Name: trxB [H]

Synonym: jk2093

Alternate gene names: 68537188

Gene position: 2451635-2452669 (Clockwise)

Preceding gene: 68537187

Following gene: 68537189

Centisome position: 99.56

GC content: 62.03

Gene sequence:

>1035_bases
ATGAACCAGCCATTCCTGCAGGCCAGCGGTATTCTCAACAATGATTCGAAGGGTGCCGCGGACGCGGATAACGCCAGCGC
GACGAGTGCAGCCGGCGCTGCGGAAGCGGAGGCAGGCAAGGTTCACGACGTCATCATCATCGGCTCCGGCCCGGCTGGCT
ACACCGCCGCTGTTTACGCAGCCCGCGCAGAGCTGAACCCGGTGGTCTTTGAAGGCGTGGAGTACGGCGGACTGCTGATG
CAGACCACCGAGGTGGAGAACTTCCCCGGCTTCCAGAAGGGCATCATGGGGCCCGACCTGATGGAAGAGATGCGCGCCCA
GGCCGAGCGTTTCGGCGCTGACCTGCGCCAAGAGGACGTAGAGAAGGTTGATCTAACCGGCGAGATCAAGAAGGTGTGGG
CTTACGGCGAGGAGTACCAAGCCCGCACAGTGATCCTGGCTACCGGCGCCGCCCCACGCTACCTGCACGTTCCCGGCGAG
CAGGAAATGCTGGGCCGTGGCGTATCCGCCTGTGCGACATGCGATGGCTTCTTCTTCAAGGACAAGCAGATCGCCGTGAT
CGGTGGCGGAGACTCCGCCATGGAGGAGGCCGACTTCCTGACGAAGTTCGGCGAGACCGTCACCATCATTCACCGCCGCG
ACGAATTCCGCGCCTCCAAGATCATGGAGGAGCGCGCCCGTAACAACCCGAAGATCAAATTCCTGACTAACGCCAAGGTC
GTGGAAGTGAAGGGCGATAAGTCCGTTGAGACTCTCGTGGTGGAAGATACCCAGAACGGCGAGCAGAAGGACGTTGCGAT
GGACGCCATGTTCGTCGCCATTGGCCATGATCCGCGCACCGCTGTCTTCGAGGGGCAGGTAGAGCTGCAGGATAACGGGT
ATGTGAAGGTCGAAGAGCCCTCCACCCGCACCAGCCTTCCTGGTGTGTTCGCCGCCGGCGACCTGGTGGATTCCCACTAC
CAGCAGGCAATCACCGCAGCTGGTTCTGGCTGCCGCGCTGCTCTGGATGCCGAGGCGTACCTCGCGACTCTTTAA

Upstream 100 bases:

>100_bases
AGCGCATGATGTACGAACACCTCGGTGGGGCAGAGGAATACGGGATGGCCGTGGCCGGTTAAACTGGAGTGAACAACATC
TCCGACCTCAAAGGATAGAT

Downstream 100 bases:

>100_bases
CTGTTTGCGGGCATGTTTTGGGGCCCGCTCCTGTTACGGATCGCGCTCCTCGTAACGGATCGGACAAGTTCGGTCACCGT
TAGGTAACTATGGCCGGTCG

Product: hypothetical protein

Products: NA

Alternate protein names: TR; TRXR [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNQPFLQASGILNNDSKGAADADNASATSAAGAAEAEAGKVHDVIIIGSGPAGYTAAVYAARAELNPVVFEGVEYGGLLM
QTTEVENFPGFQKGIMGPDLMEEMRAQAERFGADLRQEDVEKVDLTGEIKKVWAYGEEYQARTVILATGAAPRYLHVPGE
QEMLGRGVSACATCDGFFFKDKQIAVIGGGDSAMEEADFLTKFGETVTIIHRRDEFRASKIMEERARNNPKIKFLTNAKV
VEVKGDKSVETLVVEDTQNGEQKDVAMDAMFVAIGHDPRTAVFEGQVELQDNGYVKVEEPSTRTSLPGVFAAGDLVDSHY
QQAITAAGSGCRAALDAEAYLATL

Sequences:

>Translated_344_residues
MNQPFLQASGILNNDSKGAADADNASATSAAGAAEAEAGKVHDVIIIGSGPAGYTAAVYAARAELNPVVFEGVEYGGLLM
QTTEVENFPGFQKGIMGPDLMEEMRAQAERFGADLRQEDVEKVDLTGEIKKVWAYGEEYQARTVILATGAAPRYLHVPGE
QEMLGRGVSACATCDGFFFKDKQIAVIGGGDSAMEEADFLTKFGETVTIIHRRDEFRASKIMEERARNNPKIKFLTNAKV
VEVKGDKSVETLVVEDTQNGEQKDVAMDAMFVAIGHDPRTAVFEGQVELQDNGYVKVEEPSTRTSLPGVFAAGDLVDSHY
QQAITAAGSGCRAALDAEAYLATL
>Mature_344_residues
MNQPFLQASGILNNDSKGAADADNASATSAAGAAEAEAGKVHDVIIIGSGPAGYTAAVYAARAELNPVVFEGVEYGGLLM
QTTEVENFPGFQKGIMGPDLMEEMRAQAERFGADLRQEDVEKVDLTGEIKKVWAYGEEYQARTVILATGAAPRYLHVPGE
QEMLGRGVSACATCDGFFFKDKQIAVIGGGDSAMEEADFLTKFGETVTIIHRRDEFRASKIMEERARNNPKIKFLTNAKV
VEVKGDKSVETLVVEDTQNGEQKDVAMDAMFVAIGHDPRTAVFEGQVELQDNGYVKVEEPSTRTSLPGVFAAGDLVDSHY
QQAITAAGSGCRAALDAEAYLATL

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=316, Percent_Identity=51.2658227848101, Blast_Score=298, Evalue=3e-82,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=34.6031746031746, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=49.5268138801262, Blast_Score=308, Evalue=7e-85,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=48.2428115015974, Blast_Score=301, Evalue=9e-83,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 36859; Mature: 36859

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPFLQASGILNNDSKGAADADNASATSAAGAAEAEAGKVHDVIIIGSGPAGYTAAVYA
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHEEE
ARAELNPVVFEGVEYGGLLMQTTEVENFPGFQKGIMGPDLMEEMRAQAERFGADLRQEDV
HHCCCCCEEECCCCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHH
EKVDLTGEIKKVWAYGEEYQARTVILATGAAPRYLHVPGEQEMLGRGVSACATCDGFFFK
HHCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCEEECCCCHHHHHCCCHHHHCCCCEEEC
DKQIAVIGGGDSAMEEADFLTKFGETVTIIHRRDEFRASKIMEERARNNPKIKFLTNAKV
CCEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCEE
VEVKGDKSVETLVVEDTQNGEQKDVAMDAMFVAIGHDPRTAVFEGQVELQDNGYVKVEEP
EEEECCCCEEEEEEECCCCCCHHHHEEEEEEEEECCCCCCEEEECEEEECCCCEEEECCC
STRTSLPGVFAAGDLVDSHYQQAITAAGSGCRAALDAEAYLATL
CCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCEEECCHHHEECC
>Mature Secondary Structure
MNQPFLQASGILNNDSKGAADADNASATSAAGAAEAEAGKVHDVIIIGSGPAGYTAAVYA
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHEEE
ARAELNPVVFEGVEYGGLLMQTTEVENFPGFQKGIMGPDLMEEMRAQAERFGADLRQEDV
HHCCCCCEEECCCCCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHH
EKVDLTGEIKKVWAYGEEYQARTVILATGAAPRYLHVPGEQEMLGRGVSACATCDGFFFK
HHCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCEEECCCCHHHHHCCCHHHHCCCCEEEC
DKQIAVIGGGDSAMEEADFLTKFGETVTIIHRRDEFRASKIMEERARNNPKIKFLTNAKV
CCEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCEE
VEVKGDKSVETLVVEDTQNGEQKDVAMDAMFVAIGHDPRTAVFEGQVELQDNGYVKVEEP
EEEECCCCEEEEEEECCCCCCHHHHEEEEEEEEECCCCCCEEEECEEEECCCCEEEECCC
STRTSLPGVFAAGDLVDSHYQQAITAAGSGCRAALDAEAYLATL
CCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCEEECCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]