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The map label for this gene is rbsK [H]

Identifier: 68537172

GI number: 68537172

Start: 2431172

End: 2432101

Strand: Direct

Name: rbsK [H]

Synonym: jk2077

Alternate gene names: 68537172

Gene position: 2431172-2432101 (Clockwise)

Preceding gene: 68537171

Following gene: 68537173

Centisome position: 98.73

GC content: 64.3

Gene sequence:

>930_bases
ATGAGAGACTCCAACGCCACCGTCGTCGTATCCGGCACCACCAACGTCGACACCTTCGTCACTGTCCAGAACTTTCCCCA
GCCAGGGGAAACGACCATCGCAGAACCCGGCATAGAGGGGCTGGGCGGAAAGGGCGCTAATCAGGCGGCAGCCTGCGCAC
ACATGGGCGTCAATACCGTGCTTTTGTCTGCGGTAGGCAACGACCCGCAGGGCGAACTCGCAATCACAGAGCTGCGCGAA
CACGGCGTAAACACCGACTACATCGTAAGTAGCCGACAGCCAACCGGTCGGGCGTTCATCATGAATGACCCGAGTGGCGA
GAACATCATTATCGTTACCTCGGGCGCGAACGAGCTGGTCAGCCCTGCCCAGCAGCGTGAAACCGTTAAGGAACTACGCC
GCCAGGGGCCCGTGCCGATTGTGCTTGCACAGGGTGACCTGACCCCCGAGCACAGTGCGGAGCTGCCGAAGCTGGTGGAG
AACTCGGACTCCCGGCTGGTGCTAAACCTCGCACCGGTAACCACACGCGATCCCGACCTACTGGCAGCTGCCGATCCACT
GGTGCTGAATGAGGGCGAGGCCGCCGCGGTGCTCGACGCCGCCCCCGGCACGCCCATCGAGGAACTGCTGGATCGCCTGC
GCCATATCGCTCGCTCTGTGGTGGTTACCTTGGGGCAGCGCGGAGCCATGATTGTGGAAGGTGACGCCGAACCGGTGCAC
ATCCCCGCCGTTTACGTCGAGCGCGTCGTGGACACCACTGGTGCAGGCGATGCGTTCTGCGGCACGCTCGCGGCAGCGCT
GGCGCAGGGGGAGAACCTGGTGGATGCGTGCACGTTGGGCGCGGCGGCCGGGGCGCTGGCCACGCAGAAGCGCGGCGCAG
CGGGCAGCTACGCCACCGAGAACGAAATCCGTCGACTAGGAGAAGCATAA

Upstream 100 bases:

>100_bases
AGATCCCCAGTTCCGCACCCGCTGCCCCTGTTCCACCGCACTCGCCGCCCCTGTTCCACCGCGCCAGCTAACCCAGTGTT
CTTCAGTATTCTGGGGAACC

Downstream 100 bases:

>100_bases
ATGACTCAGAAGATCATCCTGGACTGCGATCCGGGGCACGACGACGCAATCGCCATGCTCCTAGCCTGGGGAAACCCTAA
CCTGGACCTGGTGGCGGTCA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MRDSNATVVVSGTTNVDTFVTVQNFPQPGETTIAEPGIEGLGGKGANQAAACAHMGVNTVLLSAVGNDPQGELAITELRE
HGVNTDYIVSSRQPTGRAFIMNDPSGENIIIVTSGANELVSPAQQRETVKELRRQGPVPIVLAQGDLTPEHSAELPKLVE
NSDSRLVLNLAPVTTRDPDLLAAADPLVLNEGEAAAVLDAAPGTPIEELLDRLRHIARSVVVTLGQRGAMIVEGDAEPVH
IPAVYVERVVDTTGAGDAFCGTLAAALAQGENLVDACTLGAAAGALATQKRGAAGSYATENEIRRLGEA

Sequences:

>Translated_309_residues
MRDSNATVVVSGTTNVDTFVTVQNFPQPGETTIAEPGIEGLGGKGANQAAACAHMGVNTVLLSAVGNDPQGELAITELRE
HGVNTDYIVSSRQPTGRAFIMNDPSGENIIIVTSGANELVSPAQQRETVKELRRQGPVPIVLAQGDLTPEHSAELPKLVE
NSDSRLVLNLAPVTTRDPDLLAAADPLVLNEGEAAAVLDAAPGTPIEELLDRLRHIARSVVVTLGQRGAMIVEGDAEPVH
IPAVYVERVVDTTGAGDAFCGTLAAALAQGENLVDACTLGAAAGALATQKRGAAGSYATENEIRRLGEA
>Mature_309_residues
MRDSNATVVVSGTTNVDTFVTVQNFPQPGETTIAEPGIEGLGGKGANQAAACAHMGVNTVLLSAVGNDPQGELAITELRE
HGVNTDYIVSSRQPTGRAFIMNDPSGENIIIVTSGANELVSPAQQRETVKELRRQGPVPIVLAQGDLTPEHSAELPKLVE
NSDSRLVLNLAPVTTRDPDLLAAADPLVLNEGEAAAVLDAAPGTPIEELLDRLRHIARSVVVTLGQRGAMIVEGDAEPVH
IPAVYVERVVDTTGAGDAFCGTLAAALAQGENLVDACTLGAAAGALATQKRGAAGSYATENEIRRLGEA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=300, Percent_Identity=30.3333333333333, Blast_Score=124, Evalue=8e-29,
Organism=Escherichia coli, GI1790193, Length=314, Percent_Identity=31.5286624203822, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI87082343, Length=291, Percent_Identity=28.5223367697594, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=310, Percent_Identity=31.2903225806452, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17541820, Length=284, Percent_Identity=27.112676056338, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319884, Length=332, Percent_Identity=27.710843373494, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24583886, Length=305, Percent_Identity=28.8524590163934, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI20128807, Length=297, Percent_Identity=32.3232323232323, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31987; Mature: 31987

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDSNATVVVSGTTNVDTFVTVQNFPQPGETTIAEPGIEGLGGKGANQAAACAHMGVNTV
CCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHE
LLSAVGNDPQGELAITELREHGVNTDYIVSSRQPTGRAFIMNDPSGENIIIVTSGANELV
EEEECCCCCCCCEEHHHHHHCCCCCCEEEECCCCCCCEEEEECCCCCEEEEEECCCHHHH
SPAQQRETVKELRRQGPVPIVLAQGDLTPEHSAELPKLVENSDSRLVLNLAPVTTRDPDL
CHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHCHHHHCCCCCEEEEEECCCCCCCCCC
LAAADPLVLNEGEAAAVLDAAPGTPIEELLDRLRHIARSVVVTLGQRGAMIVEGDAEPVH
EECCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEE
IPAVYVERVVDTTGAGDAFCGTLAAALAQGENLVDACTLGAAAGALATQKRGAAGSYATE
EHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
NEIRRLGEA
HHHHHHCCC
>Mature Secondary Structure
MRDSNATVVVSGTTNVDTFVTVQNFPQPGETTIAEPGIEGLGGKGANQAAACAHMGVNTV
CCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHE
LLSAVGNDPQGELAITELREHGVNTDYIVSSRQPTGRAFIMNDPSGENIIIVTSGANELV
EEEECCCCCCCCEEHHHHHHCCCCCCEEEECCCCCCCEEEEECCCCCEEEEEECCCHHHH
SPAQQRETVKELRRQGPVPIVLAQGDLTPEHSAELPKLVENSDSRLVLNLAPVTTRDPDL
CHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHCHHHHCCCCCEEEEEECCCCCCCCCC
LAAADPLVLNEGEAAAVLDAAPGTPIEELLDRLRHIARSVVVTLGQRGAMIVEGDAEPVH
EECCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEE
IPAVYVERVVDTTGAGDAFCGTLAAALAQGENLVDACTLGAAAGALATQKRGAAGSYATE
EHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
NEIRRLGEA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]