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The map label for this gene is adhA [H]

Identifier: 68537150

GI number: 68537150

Start: 2408236

End: 2408838

Strand: Direct

Name: adhA [H]

Synonym: jk2055

Alternate gene names: 68537150

Gene position: 2408236-2408838 (Clockwise)

Preceding gene: 68537145

Following gene: 68537151

Centisome position: 97.8

GC content: 60.86

Gene sequence:

>603_bases
ATGGACGCGGCTGCGGCGGCTACTCCCCTGCTGTGCGCTGGAATTACTACGTATTCTCCACTGAAGCACTGGGGTGTTGG
TGAGGGTTCCCGCGTGGCTGTTGTCGGCATGGGCGGCCTTGGCCATGTGGCCGTGAAGTTGGCTGCGGCGATGGGCGCGG
AGGTCACGGTGCTGAGCCACTCGAAGTCTAAGGAGGCCGATGGTCTGGCCTTTGGCGCCAACCGTTACGTAGCCACCAAG
GAGGAGGGTTGGCAGGAGCCCTTCGCTGCGCATTTCGACCTGATAATTAATACGGTCAGCGCACCGCTGGATCCGGCCCC
GTTTATTTCCACCCTCGCGCGCGGCGGGACGATGGTGATGTTGGGATTGCCCCCGGAGAAAATGCAGATCAGCGCCGATG
CGCTGATCGGTAAGCGTCGCTCCGTGGCGGGCAGTGCTATCGGTGGCATCCGGGACACCCAAGAAATGATTGATTTCTGC
GCTGCCCACGACATCACCGCGGAAACAGAGGTGATCCCGGCGGAGGATATCAACACGGCCTATCAGCGCGTGTTGGATTC
AGATGTGCGCTACCGCTTCGTCATCGACGTCAACACGATGTAG

Upstream 100 bases:

>100_bases
GTTGACTTGTTCCTTCATGATTCTTGTGGACGCCCCCTAGGCCGCCTGCGCCCGCATCCCAGCCACACAGCACAATTGCG
CTCCGGCGTAGCCTGGGGGC

Downstream 100 bases:

>100_bases
GCGCACTGACCTGACGCAGTAGTACGAGCAGTGCTTACTGCTCGGTGCCTACCACGCAGTCTTTACTGCTCCTTGGCCTG
CTCGGCCTCGATCTGCTTGC

Product: NADP-dependent alcohol dehydrogenase

Products: NA

Alternate protein names: Ms-ADHC 1 [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MDAAAAATPLLCAGITTYSPLKHWGVGEGSRVAVVGMGGLGHVAVKLAAAMGAEVTVLSHSKSKEADGLAFGANRYVATK
EEGWQEPFAAHFDLIINTVSAPLDPAPFISTLARGGTMVMLGLPPEKMQISADALIGKRRSVAGSAIGGIRDTQEMIDFC
AAHDITAETEVIPAEDINTAYQRVLDSDVRYRFVIDVNTM

Sequences:

>Translated_200_residues
MDAAAAATPLLCAGITTYSPLKHWGVGEGSRVAVVGMGGLGHVAVKLAAAMGAEVTVLSHSKSKEADGLAFGANRYVATK
EEGWQEPFAAHFDLIINTVSAPLDPAPFISTLARGGTMVMLGLPPEKMQISADALIGKRRSVAGSAIGGIRDTQEMIDFC
AAHDITAETEVIPAEDINTAYQRVLDSDVRYRFVIDVNTM
>Mature_200_residues
MDAAAAATPLLCAGITTYSPLKHWGVGEGSRVAVVGMGGLGHVAVKLAAAMGAEVTVLSHSKSKEADGLAFGANRYVATK
EEGWQEPFAAHFDLIINTVSAPLDPAPFISTLARGGTMVMLGLPPEKMQISADALIGKRRSVAGSAIGGIRDTQEMIDFC
AAHDITAETEVIPAEDINTAYQRVLDSDVRYRFVIDVNTM

Specific function: Prefers aldehydes over alcohols [H]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786518, Length=198, Percent_Identity=51.010101010101, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI87082401, Length=193, Percent_Identity=40.4145077720207, Blast_Score=118, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71988145, Length=197, Percent_Identity=30.4568527918782, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562582, Length=205, Percent_Identity=31.219512195122, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562584, Length=203, Percent_Identity=31.0344827586207, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323980, Length=194, Percent_Identity=35.5670103092784, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319949, Length=197, Percent_Identity=35.5329949238579, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=204, Percent_Identity=28.4313725490196, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=204, Percent_Identity=27.9411764705882, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323729, Length=201, Percent_Identity=26.865671641791, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.2 [H]

Molecular weight: Translated: 21044; Mature: 21044

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAAAATPLLCAGITTYSPLKHWGVGEGSRVAVVGMGGLGHVAVKLAAAMGAEVTVLSH
CCCCHHHCHHHHHCCCCCCCHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEC
SKSKEADGLAFGANRYVATKEEGWQEPFAAHFDLIINTVSAPLDPAPFISTLARGGTMVM
CCCCCCCCEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEE
LGLPPEKMQISADALIGKRRSVAGSAIGGIRDTQEMIDFCAAHDITAETEVIPAEDINTA
EECCCHHHEECHHHHHCCHHHHCCHHHCCCCHHHHHHHHHHHCCCCCCCEECCCHHHHHH
YQRVLDSDVRYRFVIDVNTM
HHHHHCCCCEEEEEEEEECC
>Mature Secondary Structure
MDAAAAATPLLCAGITTYSPLKHWGVGEGSRVAVVGMGGLGHVAVKLAAAMGAEVTVLSH
CCCCHHHCHHHHHCCCCCCCHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEC
SKSKEADGLAFGANRYVATKEEGWQEPFAAHFDLIINTVSAPLDPAPFISTLARGGTMVM
CCCCCCCCEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEE
LGLPPEKMQISADALIGKRRSVAGSAIGGIRDTQEMIDFCAAHDITAETEVIPAEDINTA
EECCCHHHEECHHHHHCCHHHHCCHHHCCCCHHHHHHHHHHHCCCCCCCEECCCHHHHHH
YQRVLDSDVRYRFVIDVNTM
HHHHHCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11257547 [H]