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The map label for this gene is qor [H]

Identifier: 68537128

GI number: 68537128

Start: 2383594

End: 2384595

Strand: Direct

Name: qor [H]

Synonym: jk2033

Alternate gene names: 68537128

Gene position: 2383594-2384595 (Clockwise)

Preceding gene: 68537126

Following gene: 68537131

Centisome position: 96.8

GC content: 63.27

Gene sequence:

>1002_bases
ATGAGCATCACCACGAACGCAATCATCCAGACCGATACCGAAAACCCCAGCTCCCTGGCCTGGCAAACCACCAGCATCGC
CGACCCCCAACCCGGCGAAGCCCTGGTGCGCATCCACTACGCGGGCGTCAATAGAGCAGACACCCTACAAGCCCAAGGCC
ACTATCCCCCACCCCACGGCACCACCGACATCATCGGACTCGAAGCCGCAGGCGTAATCGAAGACCCCAACGGAGCCACC
CGACCCGACGGCTCCCCCTGGCACCCGGGCGACGAAGTCGCAGTCCTGCTCTCCGGGGGCGGATACAGCGAATACGCCAC
CGTGCCCGAAGGCCAACTGCTGCCCATCCCCGCCGGATACAGCCTCGCCGAAGCCGCCAGCGTGGTGGAAGTTGCCTGCA
CCGTCTGGTCCAACATCATGATGACCGCCCACCTACGCGAAGGCGATACCATCCTCTTCCACGGCGGTGGCGGAGGCATC
GGCATTTTCGGCATCCAACTGGCCAAAGCACTCGGTGCCACCGTGGCCGTCACCGCCGGCTCCGAAGAAAAGCTTCACGT
ATGCCGCCGCTATGGCGCGGATATCCTCATTAACTATAAGGAGGAAGACTTCGCCGAGGTCCTGGCCGCACACGGCGGGG
CGGACGTGATTCTGGACATCATCGGCGCAAAATACCTCGACCGCAACATCAAGGCCCTGGCCCCCGACGGGCACATCGTA
ATCATCGGCATGCAAGGCGGCGTGAAAGGCGAACTGAACATCGCCAAGCTACTCAACAAACGCGGCAACATCAGCGCCAC
CGGCCTGCGCTACCGCGACAACCAAGACAAGGCAGGCATCGTCGCCGAAACCCTGCACAACGTCTGGCCGCTGCTGGAAA
ACGAGCAGATCACCCACCACATCGACCGGATCATGCCCATCGCCGAAGCCGCCGCCGCGCACAAGGCACTGCTGGCCGGG
GAAGTCACCGGCAAGATCGTGCTCGAACTGCCGCAGAGCTAG

Upstream 100 bases:

>100_bases
CATACTTCCAACGCGGCTCAATACCGCTCAAAACATCTTACACGCCACCCCACTACGCACCCCATTCCCAGCCGCACAAT
GATTCATTAGGGTGGAGACC

Downstream 100 bases:

>100_bases
GCGCGGCGCGAACGCCGCCGCGGCCACCCGCCCGTCTGCACCAACACCAGCGCCGCCAGCACCAGCAGCAGGCCAACCCA
CTGCACCAGCGAAAGCCGCT

Product: putative quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSITTNAIIQTDTENPSSLAWQTTSIADPQPGEALVRIHYAGVNRADTLQAQGHYPPPHGTTDIIGLEAAGVIEDPNGAT
RPDGSPWHPGDEVAVLLSGGGYSEYATVPEGQLLPIPAGYSLAEAASVVEVACTVWSNIMMTAHLREGDTILFHGGGGGI
GIFGIQLAKALGATVAVTAGSEEKLHVCRRYGADILINYKEEDFAEVLAAHGGADVILDIIGAKYLDRNIKALAPDGHIV
IIGMQGGVKGELNIAKLLNKRGNISATGLRYRDNQDKAGIVAETLHNVWPLLENEQITHHIDRIMPIAEAAAAHKALLAG
EVTGKIVLELPQS

Sequences:

>Translated_333_residues
MSITTNAIIQTDTENPSSLAWQTTSIADPQPGEALVRIHYAGVNRADTLQAQGHYPPPHGTTDIIGLEAAGVIEDPNGAT
RPDGSPWHPGDEVAVLLSGGGYSEYATVPEGQLLPIPAGYSLAEAASVVEVACTVWSNIMMTAHLREGDTILFHGGGGGI
GIFGIQLAKALGATVAVTAGSEEKLHVCRRYGADILINYKEEDFAEVLAAHGGADVILDIIGAKYLDRNIKALAPDGHIV
IIGMQGGVKGELNIAKLLNKRGNISATGLRYRDNQDKAGIVAETLHNVWPLLENEQITHHIDRIMPIAEAAAAHKALLAG
EVTGKIVLELPQS
>Mature_332_residues
SITTNAIIQTDTENPSSLAWQTTSIADPQPGEALVRIHYAGVNRADTLQAQGHYPPPHGTTDIIGLEAAGVIEDPNGATR
PDGSPWHPGDEVAVLLSGGGYSEYATVPEGQLLPIPAGYSLAEAASVVEVACTVWSNIMMTAHLREGDTILFHGGGGGIG
IFGIQLAKALGATVAVTAGSEEKLHVCRRYGADILINYKEEDFAEVLAAHGGADVILDIIGAKYLDRNIKALAPDGHIVI
IGMQGGVKGELNIAKLLNKRGNISATGLRYRDNQDKAGIVAETLHNVWPLLENEQITHHIDRIMPIAEAAAAHKALLAGE
VTGKIVLELPQS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=326, Percent_Identity=38.6503067484663, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI22538444, Length=326, Percent_Identity=38.6503067484663, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI194239674, Length=312, Percent_Identity=24.6794871794872, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI13236495, Length=312, Percent_Identity=24.6794871794872, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI28557745, Length=324, Percent_Identity=26.5432098765432, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI18379349, Length=315, Percent_Identity=26.3492063492064, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI41872631, Length=257, Percent_Identity=28.0155642023346, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI24308257, Length=328, Percent_Identity=23.1707317073171, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI194239676, Length=190, Percent_Identity=27.3684210526316, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI47519420, Length=227, Percent_Identity=29.0748898678414, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1790485, Length=245, Percent_Identity=30.6122448979592, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17507255, Length=307, Percent_Identity=23.4527687296417, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI212642053, Length=350, Percent_Identity=24.8571428571429, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=312, Percent_Identity=27.2435897435897, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323961, Length=284, Percent_Identity=29.2253521126761, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=264, Percent_Identity=27.6515151515151, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=284, Percent_Identity=25.3521126760563, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=259, Percent_Identity=26.2548262548263, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24581345, Length=252, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920632, Length=255, Percent_Identity=23.921568627451, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221330659, Length=255, Percent_Identity=23.921568627451, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35079; Mature: 34948

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITTNAIIQTDTENPSSLAWQTTSIADPQPGEALVRIHYAGVNRADTLQAQGHYPPPHG
CCEECCEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCC
TTDIIGLEAAGVIEDPNGATRPDGSPWHPGDEVAVLLSGGGYSEYATVPEGQLLPIPAGY
CCEEEEEEECCEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCEEECCCCC
SLAEAASVVEVACTVWSNIMMTAHLREGDTILFHGGGGGIGIFGIQLAKALGATVAVTAG
CHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCEEHHHHHHHHHHCCEEEEECC
SEEKLHVCRRYGADILINYKEEDFAEVLAAHGGADVILDIIGAKYLDRNIKALAPDGHIV
CCHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCEE
IIGMQGGVKGELNIAKLLNKRGNISATGLRYRDNQDKAGIVAETLHNVWPLLENEQITHH
EEEECCCCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHH
IDRIMPIAEAAAAHKALLAGEVTGKIVLELPQS
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
>Mature Secondary Structure 
SITTNAIIQTDTENPSSLAWQTTSIADPQPGEALVRIHYAGVNRADTLQAQGHYPPPHG
CEECCEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCC
TTDIIGLEAAGVIEDPNGATRPDGSPWHPGDEVAVLLSGGGYSEYATVPEGQLLPIPAGY
CCEEEEEEECCEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCEEECCCCC
SLAEAASVVEVACTVWSNIMMTAHLREGDTILFHGGGGGIGIFGIQLAKALGATVAVTAG
CHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCEEHHHHHHHHHHCCEEEEECC
SEEKLHVCRRYGADILINYKEEDFAEVLAAHGGADVILDIIGAKYLDRNIKALAPDGHIV
CCHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCEE
IIGMQGGVKGELNIAKLLNKRGNISATGLRYRDNQDKAGIVAETLHNVWPLLENEQITHH
EEEECCCCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHH
IDRIMPIAEAAAAHKALLAGEVTGKIVLELPQS
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]