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The map label for this gene is 68536794

Identifier: 68536794

GI number: 68536794

Start: 1987106

End: 1988398

Strand: Direct

Name: 68536794

Synonym: jk1704

Alternate gene names: NA

Gene position: 1987106-1988398 (Clockwise)

Preceding gene: 68536785

Following gene: 68536797

Centisome position: 80.69

GC content: 65.89

Gene sequence:

>1293_bases
ATGAGCAACTCCCCCTCCCGCAGCTTCGACCGCAGCTTCGACATCACCCTGATGGGTGCCACCGGTTTCGTCGGCGCGCT
GACCGCCGGCTACCTGGCCGCCAACGCTCCCGCCGACGTGCGCATCGCCCTGGCTGGCCGGAACCAGACCAAGCTAGAAG
CCCTGCGCGAGCAGCTGGCTGCAAAGCACCCGCGGGCGGCGGACTTCCCTCTAGTCATCGCCGATTCCAGCGATAATCGC
TCCCTGGAGAAGCTGGCTCGCGATACCCGTGTGGTTATCTCCACCGTCGGCCCCTATTACCGCTATGGGTTCCCCCTGGT
CCGCGAATGCGCCACCCACGGCACGCACTATGTCGACCTCGCCGGAGAAGCGCTCTTCATGCGCGAATCCGCGGATTCCT
ACCACGACCGCGCCACCGCCAGCGGGGCGCGCATCGTCCACGCCTGCGGCTTCGATTCCGTTCCGAGTGACCTGGGAATG
CTACTGCTGGGACAGAGGGCGTCCGAAAATAAAGACAGCCTCAAGTCCGCCACCATGATCGTGAAGATGAAGGGCGGGCT
CTCCGGCGGCACGATCGACTCGATGCGCGAACAATTCGCAGCCGCCAAGGGCAACCAGGAGAAGAAGCGGCTGCTAGCCG
ACCCGTACACCCTCTCCCCCGACCGTGCCAAAGAGCCGGACCTGGGCAAGCAGCCGGACTTCGGTGTAGTGCGGGAAAGC
GACATCGGGGGTGCTAGCGCTAGCGACGGCGAGGACGTCTGGGCCGGGCCGTTCATCATGGCGGGCTCCAACACGCGCGT
GGTGCGCCGCTCGAACGCGCTGCTCGGCTACGAATACGGCGATAAGCTGCGCTACAGCGAATACCAGTACACCGGCAAGG
GGCTGAAGGGTCGCATGCGTGCCTTCACCATGGGCGCGGTGCTCGGCACTGCGGTGGCGGCGCTGAACCAGGACAAGCTG
CGCACGTTCCTCTCTCGCTGGGTGCCGGAGCCCGGCGAGGGGCCGTCCGAGGCCGAACGCGATTCCGGCTTCTTCCACAC
CACGCATTTCGGCGTGGGCAACAGCGGAGCCACCTACACCCAAACCATCAGCCTGGACGCCGACCCGGGGTACAAGGGCA
CGTCCCTGATGCTTAGCGAGGCTGCGCTCACTCTTGTTCTTTGTGACGCCGAACTGCCGACAGGCTCCGCCTACCAAGGA
AAAACCGGCGGCGGAGTGCTCACTCCGGCCACCGGCCTGGGGATGCCCTACGTGCGCCGCCTCGGCGACGCGGGCATGAA
GTTCAGCGACTAG

Upstream 100 bases:

>100_bases
GGATCTCCGGGCGGTCGAAGACTACGTGCAGTGGTGGGTTCACACCCGCAAACTGGTTTTCAGACGTCATTCCCTCAATC
TAACCGGTACAAATGTAGCC

Downstream 100 bases:

>100_bases
TTGAACATGCCTAGCTGAACAGGTTCTGCTCGTCCTCGGGCACGCCGTTCACCTGGTTTAGGTTCAGAGTATTGAGCTGG
GTGACGTGCTCCGGGGTCAG

Product: putative secreted protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MSNSPSRSFDRSFDITLMGATGFVGALTAGYLAANAPADVRIALAGRNQTKLEALREQLAAKHPRAADFPLVIADSSDNR
SLEKLARDTRVVISTVGPYYRYGFPLVRECATHGTHYVDLAGEALFMRESADSYHDRATASGARIVHACGFDSVPSDLGM
LLLGQRASENKDSLKSATMIVKMKGGLSGGTIDSMREQFAAAKGNQEKKRLLADPYTLSPDRAKEPDLGKQPDFGVVRES
DIGGASASDGEDVWAGPFIMAGSNTRVVRRSNALLGYEYGDKLRYSEYQYTGKGLKGRMRAFTMGAVLGTAVAALNQDKL
RTFLSRWVPEPGEGPSEAERDSGFFHTTHFGVGNSGATYTQTISLDADPGYKGTSLMLSEAALTLVLCDAELPTGSAYQG
KTGGGVLTPATGLGMPYVRRLGDAGMKFSD

Sequences:

>Translated_430_residues
MSNSPSRSFDRSFDITLMGATGFVGALTAGYLAANAPADVRIALAGRNQTKLEALREQLAAKHPRAADFPLVIADSSDNR
SLEKLARDTRVVISTVGPYYRYGFPLVRECATHGTHYVDLAGEALFMRESADSYHDRATASGARIVHACGFDSVPSDLGM
LLLGQRASENKDSLKSATMIVKMKGGLSGGTIDSMREQFAAAKGNQEKKRLLADPYTLSPDRAKEPDLGKQPDFGVVRES
DIGGASASDGEDVWAGPFIMAGSNTRVVRRSNALLGYEYGDKLRYSEYQYTGKGLKGRMRAFTMGAVLGTAVAALNQDKL
RTFLSRWVPEPGEGPSEAERDSGFFHTTHFGVGNSGATYTQTISLDADPGYKGTSLMLSEAALTLVLCDAELPTGSAYQG
KTGGGVLTPATGLGMPYVRRLGDAGMKFSD
>Mature_429_residues
SNSPSRSFDRSFDITLMGATGFVGALTAGYLAANAPADVRIALAGRNQTKLEALREQLAAKHPRAADFPLVIADSSDNRS
LEKLARDTRVVISTVGPYYRYGFPLVRECATHGTHYVDLAGEALFMRESADSYHDRATASGARIVHACGFDSVPSDLGML
LLGQRASENKDSLKSATMIVKMKGGLSGGTIDSMREQFAAAKGNQEKKRLLADPYTLSPDRAKEPDLGKQPDFGVVRESD
IGGASASDGEDVWAGPFIMAGSNTRVVRRSNALLGYEYGDKLRYSEYQYTGKGLKGRMRAFTMGAVLGTAVAALNQDKLR
TFLSRWVPEPGEGPSEAERDSGFFHTTHFGVGNSGATYTQTISLDADPGYKGTSLMLSEAALTLVLCDAELPTGSAYQGK
TGGGVLTPATGLGMPYVRRLGDAGMKFSD

Specific function: Unknown

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=447, Percent_Identity=27.9642058165548, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17560066, Length=431, Percent_Identity=25.2900232018561, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32567112, Length=410, Percent_Identity=25.1219512195122, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI71991033, Length=154, Percent_Identity=31.8181818181818, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24644140, Length=456, Percent_Identity=28.5087719298246, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24644142, Length=456, Percent_Identity=28.5087719298246, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21356081, Length=456, Percent_Identity=28.5087719298246, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24646278, Length=457, Percent_Identity=26.6958424507659, Blast_Score=118, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 45919; Mature: 45788

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSPSRSFDRSFDITLMGATGFVGALTAGYLAANAPADVRIALAGRNQTKLEALREQLA
CCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHH
AKHPRAADFPLVIADSSDNRSLEKLARDTRVVISTVGPYYRYGFPLVRECATHGTHYVDL
HCCCCCCCCCEEEECCCCCHHHHHHHHHCEEEEECCCCHHHHCCHHHHHHHHCCCEEEEE
AGEALFMRESADSYHDRATASGARIVHACGFDSVPSDLGMLLLGQRASENKDSLKSATMI
CCCEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHEECCCCCCCHHHHHHEEEE
VKMKGGLSGGTIDSMREQFAAAKGNQEKKRLLADPYTLSPDRAKEPDLGKQPDFGVVRES
EEECCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEECC
DIGGASASDGEDVWAGPFIMAGSNTRVVRRSNALLGYEYGDKLRYSEYQYTGKGLKGRMR
CCCCCCCCCCCCEECCCEEEECCCCEEEEECCCEEEECCCCCCCCCCEEECCCCCCCHHH
AFTMGAVLGTAVAALNQDKLRTFLSRWVPEPGEGPSEAERDSGFFHTTHFGVGNSGATYT
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEECCCCCCCCEEE
QTISLDADPGYKGTSLMLSEAALTLVLCDAELPTGSAYQGKTGGGVLTPATGLGMPYVRR
EEEEECCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCHHHHH
LGDAGMKFSD
HCCCCCCCCC
>Mature Secondary Structure 
SNSPSRSFDRSFDITLMGATGFVGALTAGYLAANAPADVRIALAGRNQTKLEALREQLA
CCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHH
AKHPRAADFPLVIADSSDNRSLEKLARDTRVVISTVGPYYRYGFPLVRECATHGTHYVDL
HCCCCCCCCCEEEECCCCCHHHHHHHHHCEEEEECCCCHHHHCCHHHHHHHHCCCEEEEE
AGEALFMRESADSYHDRATASGARIVHACGFDSVPSDLGMLLLGQRASENKDSLKSATMI
CCCEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHEECCCCCCCHHHHHHEEEE
VKMKGGLSGGTIDSMREQFAAAKGNQEKKRLLADPYTLSPDRAKEPDLGKQPDFGVVRES
EEECCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEECC
DIGGASASDGEDVWAGPFIMAGSNTRVVRRSNALLGYEYGDKLRYSEYQYTGKGLKGRMR
CCCCCCCCCCCCEECCCEEEECCCCEEEEECCCEEEECCCCCCCCCCEEECCCCCCCHHH
AFTMGAVLGTAVAALNQDKLRTFLSRWVPEPGEGPSEAERDSGFFHTTHFGVGNSGATYT
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEECCCCCCCCEEE
QTISLDADPGYKGTSLMLSEAALTLVLCDAELPTGSAYQGKTGGGVLTPATGLGMPYVRR
EEEEECCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCHHHHH
LGDAGMKFSD
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]