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The map label for this gene is metX

Identifier: 68536785

GI number: 68536785

Start: 1976196

End: 1977383

Strand: Direct

Name: metX

Synonym: jk1695

Alternate gene names: 68536785

Gene position: 1976196-1977383 (Clockwise)

Preceding gene: 68536784

Following gene: 68536794

Centisome position: 80.25

GC content: 65.4

Gene sequence:

>1188_bases
ATGAACCCCGAGTTCCTCCCCGCTTCTGGCGCGTCGCGCACTGTCTCTATCGGCGACGTTGTCACGGAGGCGGGTGTAAC
TATTTTTGACGCCGAACTCCGCTACTTCGCGTTCTACGACTCTCCGGATGGCGCCGCGGACTATGCCGAGTTCTCCGCTG
GCCCCGAGCCGGGCCTGTCCCCGGAGGAACGACCGATTGTTCTGATCGAGCATGCCCTCACCGGCGATGGCAATGCCGCC
GACTGGTGGGCGGACATGGTGGGTCCGAACAAGCCGATTGATACCACCCGCTACCTGGTGCTCTGCGCGAATGTGCTGGG
CGGCTGCCAGGGGTCCACCGGCCCGAGTTCGCCGCACCCCGATGGCCAGGCGTGGGGGTCGCGATTCCCGGGCCTGTCGA
TCCGTGACATGGTTACGGCGGAACGGCAGTTGTTGGAGCGTGTGGGCGTCACAAAGATTCATGCATTGATTGGCGCCTCG
ATGGGCGGGGCGCGGGTGCTGGAGTGGTCGCTCATGCACCCGGAGATGATCAACGCGGCGCTGCCGATCGCGGTGAGCGC
GCGTGCGTCTGCGTGGCAGATCGGCCTGCAGTCCAGCCAGATCCGCTTCATTGAGGCGGACCCGGCCTGGCACGGTGGCG
ACTACTACGACACGGGTGAGGTTCCTTCGCACGGGCTGGGGCAGGCCCGCCGCATCGCGCACCTGACGTACCGCGGCGAG
TTGGAGGTGGACGAGCGTTTCGGGGTGGATCCGCAGAACGGCGAGAACCCCTACGGGCCGTACCGCGACCCGCACCAGCG
CTTCGCGGTGGAAAGCTACCTGGATCGCCAGGCAGAGAAGCTGGTGGCACGCTTCGATGCGGGCAGCTACGTGGTGCTAA
CCGACGCGCTGAACAGGCACGACGTCGGCCGTAGCCGGGGTGGCATGAACGCTGCCCTGGGCTCGTGTGAGGTGCCGACG
ATGGTGGTAGGTGTGGATACCGACATTCTGTATCCGCTGCACCAGCAGGAGCACCTGTCGCGCAATCTGGGGGACTTCAT
CGGCATGTCGAAGATCACCTCTCCGACGGGTCACGATGGGTTTCTGATTGAGTCACGCCAGATGGGGCAGGCGTTGGCGA
AGTTCCTGGCGAAGGCGGAGATCATCGCCGAAGGTACCGAGGGCGCCGAGGGAACTGCGCGGGCTTAG

Upstream 100 bases:

>100_bases
TCTGTGGGCATCGAAGACATCACCGACATCATCAACGACCTGAAGCTCGGCTTCGCAGCCATCTAAGGTTGTTAGGTTTC
TAGGCTTTAGGCTGATTTCC

Downstream 100 bases:

>100_bases
CTGGTCAGCGGGTCGACGCTCACGGCGATCCACAAAATGATTATGCCGATGGCGGCTGTGAAGGCGGTATCGAACTTGCG
CGAACGCACCGCCAGCACGC

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MNPEFLPASGASRTVSIGDVVTEAGVTIFDAELRYFAFYDSPDGAADYAEFSAGPEPGLSPEERPIVLIEHALTGDGNAA
DWWADMVGPNKPIDTTRYLVLCANVLGGCQGSTGPSSPHPDGQAWGSRFPGLSIRDMVTAERQLLERVGVTKIHALIGAS
MGGARVLEWSLMHPEMINAALPIAVSARASAWQIGLQSSQIRFIEADPAWHGGDYYDTGEVPSHGLGQARRIAHLTYRGE
LEVDERFGVDPQNGENPYGPYRDPHQRFAVESYLDRQAEKLVARFDAGSYVVLTDALNRHDVGRSRGGMNAALGSCEVPT
MVVGVDTDILYPLHQQEHLSRNLGDFIGMSKITSPTGHDGFLIESRQMGQALAKFLAKAEIIAEGTEGAEGTARA

Sequences:

>Translated_395_residues
MNPEFLPASGASRTVSIGDVVTEAGVTIFDAELRYFAFYDSPDGAADYAEFSAGPEPGLSPEERPIVLIEHALTGDGNAA
DWWADMVGPNKPIDTTRYLVLCANVLGGCQGSTGPSSPHPDGQAWGSRFPGLSIRDMVTAERQLLERVGVTKIHALIGAS
MGGARVLEWSLMHPEMINAALPIAVSARASAWQIGLQSSQIRFIEADPAWHGGDYYDTGEVPSHGLGQARRIAHLTYRGE
LEVDERFGVDPQNGENPYGPYRDPHQRFAVESYLDRQAEKLVARFDAGSYVVLTDALNRHDVGRSRGGMNAALGSCEVPT
MVVGVDTDILYPLHQQEHLSRNLGDFIGMSKITSPTGHDGFLIESRQMGQALAKFLAKAEIIAEGTEGAEGTARA
>Mature_395_residues
MNPEFLPASGASRTVSIGDVVTEAGVTIFDAELRYFAFYDSPDGAADYAEFSAGPEPGLSPEERPIVLIEHALTGDGNAA
DWWADMVGPNKPIDTTRYLVLCANVLGGCQGSTGPSSPHPDGQAWGSRFPGLSIRDMVTAERQLLERVGVTKIHALIGAS
MGGARVLEWSLMHPEMINAALPIAVSARASAWQIGLQSSQIRFIEADPAWHGGDYYDTGEVPSHGLGQARRIAHLTYRGE
LEVDERFGVDPQNGENPYGPYRDPHQRFAVESYLDRQAEKLVARFDAGSYVVLTDALNRHDVGRSRGGMNAALGSCEVPT
MVVGVDTDILYPLHQQEHLSRNLGDFIGMSKITSPTGHDGFLIESRQMGQALAKFLAKAEIIAEGTEGAEGTARA

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=249, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_CORJK (Q4JTI5)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_251490.1
- ProteinModelPortal:   Q4JTI5
- SMR:   Q4JTI5
- STRING:   Q4JTI5
- GeneID:   3433308
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk1695
- NMPDR:   fig|306537.3.peg.1464
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   PRK00175
- BioCyc:   CJEI306537:JK1695-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 42548; Mature: 42548

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: ACT_SITE 160-160 ACT_SITE 358-358

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPEFLPASGASRTVSIGDVVTEAGVTIFDAELRYFAFYDSPDGAADYAEFSAGPEPGLS
CCCCCCCCCCCCCEEEHHHHHHHCCCEEEECCEEEEEEECCCCCCCHHHHHCCCCCCCCC
PEERPIVLIEHALTGDGNAADWWADMVGPNKPIDTTRYLVLCANVLGGCQGSTGPSSPHP
CCCCCEEEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
DGQAWGSRFPGLSIRDMVTAERQLLERVGVTKIHALIGASMGGARVLEWSLMHPEMINAA
CCHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
LPIAVSARASAWQIGLQSSQIRFIEADPAWHGGDYYDTGEVPSHGLGQARRIAHLTYRGE
CCEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEECC
LEVDERFGVDPQNGENPYGPYRDPHQRFAVESYLDRQAEKLVARFDAGSYVVLTDALNRH
EEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
DVGRSRGGMNAALGSCEVPTMVVGVDTDILYPLHQQEHLSRNLGDFIGMSKITSPTGHDG
CCCCCCCCCHHHCCCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
FLIESRQMGQALAKFLAKAEIIAEGTEGAEGTARA
EEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNPEFLPASGASRTVSIGDVVTEAGVTIFDAELRYFAFYDSPDGAADYAEFSAGPEPGLS
CCCCCCCCCCCCCEEEHHHHHHHCCCEEEECCEEEEEEECCCCCCCHHHHHCCCCCCCCC
PEERPIVLIEHALTGDGNAADWWADMVGPNKPIDTTRYLVLCANVLGGCQGSTGPSSPHP
CCCCCEEEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
DGQAWGSRFPGLSIRDMVTAERQLLERVGVTKIHALIGASMGGARVLEWSLMHPEMINAA
CCHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
LPIAVSARASAWQIGLQSSQIRFIEADPAWHGGDYYDTGEVPSHGLGQARRIAHLTYRGE
CCEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEECC
LEVDERFGVDPQNGENPYGPYRDPHQRFAVESYLDRQAEKLVARFDAGSYVVLTDALNRH
EEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
DVGRSRGGMNAALGSCEVPTMVVGVDTDILYPLHQQEHLSRNLGDFIGMSKITSPTGHDG
CCCCCCCCCHHHCCCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
FLIESRQMGQALAKFLAKAEIIAEGTEGAEGTARA
EEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA