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The map label for this gene is pmmB [C]

Identifier: 68536765

GI number: 68536765

Start: 1953675

End: 1955210

Strand: Direct

Name: pmmB [C]

Synonym: jk1675

Alternate gene names: 68536765

Gene position: 1953675-1955210 (Clockwise)

Preceding gene: 68536764

Following gene: 68536767

Centisome position: 79.34

GC content: 66.93

Gene sequence:

>1536_bases
ATGAGCCAGCTGAAGTTCGGCACCGCCGGCCTGCGCGCCAAGATCGGCCCCGGACCAGAGGAAATGAACGTCGGCACCGT
CACCCGCGCCACGGCTGGTGTGGCTGCGTGGCTTAAGGAACGGAAGCGCCCCTTGCGCGCCGACGGGGTTTTTCGCGCTG
CGGTGGGATATGACGCCCGCTACGCCTCCCACGCCCTAGCCCGCGCTACGGCGGAAACATTCGCCGGTGCAGGCTTCGAC
GTGACCCTCATCGCTGAACCCGCCCCCACCCCAGTGCTGGCGTGGCTGGTACGCTCCCGGCGAATGGATGTGGGCGTGCA
AATCACCGCCTCGCACAACCCCGCGCAGGACAACGGCTACAAGCTGTACCTGGACGGCGGCTCTCAGCTGGTCTCCCCCG
CCGACCGGCAGATCGAAGAGCACATTGCCGCCCAGCCAACCGACGCGGCGGAGATTCCGCGCTCTGAGGCGAAGTCGGTA
GACCTGTCCGTAGTCTCCGGCTATGTCACCGAGCTAAGTACCCTGGTGGCCACCGGCCGCCAATCCGAGCTGGCGCCACG
GCGAAAGCTGAAGATCCTCTACACCCCCATGCACGGCGTGGGTGGCAACGCACTGGAGTGGGCACTTCGTGAGAACGGCT
TCGGCAACGTGCACGCGGTGGCCTCGCAGCGCTGGCCGGATCCAACCTTCCCGACGGTGGACTTCCCAAACCCGGAGGAG
CCCGGCGCCACCGACGCGCTATTGGAAGAAGCCCGCGCCATCGACGCAGACCTGCTGATCGCTCTTGATCCGGATGCGGA
CCGCTGCATGCTGGGGCTCAAGCGCGCGGATGGCGAGTACCACATGCTGCGCGGGGACGAGACCGGCCCCTTGCTGGCGC
GCCGGGTGCTGGCGGACGTGGGGGCGTCCATAAAGAAAAAACCTGTGGTGGCGACAACGGTGGTCAGTTCGCAGCTGCTG
GGGCGCATGGCGCGCGCCGAGGGCTGGGATTACGTGGAGACGCTGACTGGTTTTAAGAACCTGGCGCGCGCTGCCGACAA
TCGGCCGGGCGAGCTGACCTTCGCCTACGAGGAGGCGATCGGCACCGCGCCTGCGCCACACATCGTGGCGGATAAGGATG
GCATTGCGACGGCACTGATCGCGGCGGCGTGGGCAGCCGAGGCAGACCTGGTCGCCGAGTTGGACGACATTGAGGCCACC
TATGGAGTATTCAGAACCTCACAGGTGAGCGCCCGTTTCGACAGTGCCGAGCAAGCCCAAGAGTTGATCGCTCGCTGGAC
GGATAATCCGCCGGCTGAGCTCGCAGGTGCGGCCATGCAGGCCGGGCCGATCGAGGATTCCGCTGGCAACCGCACCGACG
GCGTGCGACTGGTGGGCACTTCCGCGAATATGGGGCTGCGCGTAGTGGCCCGCGCGTCCGGCACCGAGCCGAAGGCGAAG
TTCTACCTGGAGGTCAGCGCGGAGCCAGGGACGGACCCACAGGCCGTGGGGGCGCTGCTAGAGCGGCTACAGGTCGATGT
TTCGGGGGCCGTATAG

Upstream 100 bases:

>100_bases
GAGTTACCGGCGAACCCCTGAACCACGAGGAAGTCCTGCAGGCGGGCAAGGAAGCTGCCAACGACATGGGCAAGTTGCTC
GGCGAGCTGGTGAACAACCT

Downstream 100 bases:

>100_bases
GCGGTCACCGGCATCGCCCAGGCCGGGCACGATGTACGCCTCCTTGTTCAGGCTCGGGTCAATAGTGGCGGTGTACAGCC
GGCGCACCCCCACGTTGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MSQLKFGTAGLRAKIGPGPEEMNVGTVTRATAGVAAWLKERKRPLRADGVFRAAVGYDARYASHALARATAETFAGAGFD
VTLIAEPAPTPVLAWLVRSRRMDVGVQITASHNPAQDNGYKLYLDGGSQLVSPADRQIEEHIAAQPTDAAEIPRSEAKSV
DLSVVSGYVTELSTLVATGRQSELAPRRKLKILYTPMHGVGGNALEWALRENGFGNVHAVASQRWPDPTFPTVDFPNPEE
PGATDALLEEARAIDADLLIALDPDADRCMLGLKRADGEYHMLRGDETGPLLARRVLADVGASIKKKPVVATTVVSSQLL
GRMARAEGWDYVETLTGFKNLARAADNRPGELTFAYEEAIGTAPAPHIVADKDGIATALIAAAWAAEADLVAELDDIEAT
YGVFRTSQVSARFDSAEQAQELIARWTDNPPAELAGAAMQAGPIEDSAGNRTDGVRLVGTSANMGLRVVARASGTEPKAK
FYLEVSAEPGTDPQAVGALLERLQVDVSGAV

Sequences:

>Translated_511_residues
MSQLKFGTAGLRAKIGPGPEEMNVGTVTRATAGVAAWLKERKRPLRADGVFRAAVGYDARYASHALARATAETFAGAGFD
VTLIAEPAPTPVLAWLVRSRRMDVGVQITASHNPAQDNGYKLYLDGGSQLVSPADRQIEEHIAAQPTDAAEIPRSEAKSV
DLSVVSGYVTELSTLVATGRQSELAPRRKLKILYTPMHGVGGNALEWALRENGFGNVHAVASQRWPDPTFPTVDFPNPEE
PGATDALLEEARAIDADLLIALDPDADRCMLGLKRADGEYHMLRGDETGPLLARRVLADVGASIKKKPVVATTVVSSQLL
GRMARAEGWDYVETLTGFKNLARAADNRPGELTFAYEEAIGTAPAPHIVADKDGIATALIAAAWAAEADLVAELDDIEAT
YGVFRTSQVSARFDSAEQAQELIARWTDNPPAELAGAAMQAGPIEDSAGNRTDGVRLVGTSANMGLRVVARASGTEPKAK
FYLEVSAEPGTDPQAVGALLERLQVDVSGAV
>Mature_510_residues
SQLKFGTAGLRAKIGPGPEEMNVGTVTRATAGVAAWLKERKRPLRADGVFRAAVGYDARYASHALARATAETFAGAGFDV
TLIAEPAPTPVLAWLVRSRRMDVGVQITASHNPAQDNGYKLYLDGGSQLVSPADRQIEEHIAAQPTDAAEIPRSEAKSVD
LSVVSGYVTELSTLVATGRQSELAPRRKLKILYTPMHGVGGNALEWALRENGFGNVHAVASQRWPDPTFPTVDFPNPEEP
GATDALLEEARAIDADLLIALDPDADRCMLGLKRADGEYHMLRGDETGPLLARRVLADVGASIKKKPVVATTVVSSQLLG
RMARAEGWDYVETLTGFKNLARAADNRPGELTFAYEEAIGTAPAPHIVADKDGIATALIAAAWAAEADLVAELDDIEATY
GVFRTSQVSARFDSAEQAQELIARWTDNPPAELAGAAMQAGPIEDSAGNRTDGVRLVGTSANMGLRVVARASGTEPKAKF
YLEVSAEPGTDPQAVGALLERLQVDVSGAV

Specific function: Unknown

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=553, Percent_Identity=31.6455696202532, Blast_Score=233, Evalue=5e-61,
Organism=Homo sapiens, GI31377548, Length=550, Percent_Identity=29.2727272727273, Blast_Score=193, Evalue=3e-49,
Organism=Escherichia coli, GI1789566, Length=302, Percent_Identity=29.1390728476821, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788361, Length=490, Percent_Identity=25.7142857142857, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71993870, Length=551, Percent_Identity=32.486388384755, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71993878, Length=286, Percent_Identity=35.3146853146853, Blast_Score=141, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6323934, Length=552, Percent_Identity=31.3405797101449, Blast_Score=221, Evalue=2e-58,
Organism=Drosophila melanogaster, GI20129809, Length=541, Percent_Identity=32.902033271719, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI24651977, Length=457, Percent_Identity=34.3544857768052, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24653722, Length=423, Percent_Identity=28.8416075650118, Blast_Score=162, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 54223; Mature: 54091

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLKFGTAGLRAKIGPGPEEMNVGTVTRATAGVAAWLKERKRPLRADGVFRAAVGYDAR
CCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHCCCHH
YASHALARATAETFAGAGFDVTLIAEPAPTPVLAWLVRSRRMDVGVQITASHNPAQDNGY
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCE
KLYLDGGSQLVSPADRQIEEHIAAQPTDAAEIPRSEAKSVDLSVVSGYVTELSTLVATGR
EEEECCCCCCCCCHHHHHHHHHCCCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHCCC
QSELAPRRKLKILYTPMHGVGGNALEWALRENGFGNVHAVASQRWPDPTFPTVDFPNPEE
CHHCCCCCCEEEEEECCCCCCCCCEEHHHHCCCCCCEEEEHHCCCCCCCCCCCCCCCCCC
PGATDALLEEARAIDADLLIALDPDADRCMLGLKRADGEYHMLRGDETGPLLARRVLADV
CCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHH
GASIKKKPVVATTVVSSQLLGRMARAEGWDYVETLTGFKNLARAADNRPGELTFAYEEAI
CCCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHC
GTAPAPHIVADKDGIATALIAAAWAAEADLVAELDDIEATYGVFRTSQVSARFDSAEQAQ
CCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHH
ELIARWTDNPPAELAGAAMQAGPIEDSAGNRTDGVRLVGTSANMGLRVVARASGTEPKAK
HHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCEE
FYLEVSAEPGTDPQAVGALLERLQVDVSGAV
EEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQLKFGTAGLRAKIGPGPEEMNVGTVTRATAGVAAWLKERKRPLRADGVFRAAVGYDAR
CCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHCCCHH
YASHALARATAETFAGAGFDVTLIAEPAPTPVLAWLVRSRRMDVGVQITASHNPAQDNGY
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCE
KLYLDGGSQLVSPADRQIEEHIAAQPTDAAEIPRSEAKSVDLSVVSGYVTELSTLVATGR
EEEECCCCCCCCCHHHHHHHHHCCCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHCCC
QSELAPRRKLKILYTPMHGVGGNALEWALRENGFGNVHAVASQRWPDPTFPTVDFPNPEE
CHHCCCCCCEEEEEECCCCCCCCCEEHHHHCCCCCCEEEEHHCCCCCCCCCCCCCCCCCC
PGATDALLEEARAIDADLLIALDPDADRCMLGLKRADGEYHMLRGDETGPLLARRVLADV
CCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHH
GASIKKKPVVATTVVSSQLLGRMARAEGWDYVETLTGFKNLARAADNRPGELTFAYEEAI
CCCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHC
GTAPAPHIVADKDGIATALIAAAWAAEADLVAELDDIEATYGVFRTSQVSARFDSAEQAQ
CCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHH
ELIARWTDNPPAELAGAAMQAGPIEDSAGNRTDGVRLVGTSANMGLRVVARASGTEPKAK
HHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCEE
FYLEVSAEPGTDPQAVGALLERLQVDVSGAV
EEEEEECCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]