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The map label for this gene is fadE6 [H]

Identifier: 68536548

GI number: 68536548

Start: 1722207

End: 1723382

Strand: Direct

Name: fadE6 [H]

Synonym: jk1462

Alternate gene names: 68536548

Gene position: 1722207-1723382 (Clockwise)

Preceding gene: 68536547

Following gene: 68536552

Centisome position: 69.94

GC content: 61.39

Gene sequence:

>1176_bases
ATGAAGAACTTCCTGCCACGCAACATTTTCGAAGAAGAGCACAACATGTTCCGCGAGGCCTGCGCGGACTTCGTGAAGGC
CGAGATCGCCCCGAACGTTGACCGCTGGCACGAGCAGGGCTACTGCGACCGTGAGATGTTCCAGAAGGCTGGTCAGCAGG
GCCTGCTGGGCATGATGGCACCGGAACAGTTCGGCGGCGGCGGTATGGAGAACGACTACCGCTTCAACGCTGTACTGACC
GAGGAGCTGGCTAAGGCTGACTCTGGTTCCGTCATCGTGGGCATCCAGACCATCAACGACCTGGTCATTCCTTACCTGCA
GCGCTTCGGCAACGACGATCAGAAGGAGCGTTTCCTGAAGCCGCTGTGTGCCGGTGAGAAGATCGCCGCACTGGCAATGA
CCGAGCCGGGCGCAGGCGCCGACCTGGCTGGCATCCGCACCTTCGCTAAGAAGGACGAGAACGGCGACTACATCGTCAAC
GGCGCAAAGACCTTCATCTCCAACGGTGTCCAGGCAGACTTCACCCTGCTGGTCGTCGTGACCAACCCGGAGAAGGGCCG
CGCAGGCGTTTCCATGCTGATCGTTGAGGACGGTATGGAGGGCTACACCAAGACCGGCCCGCTGAAGAAGGTCGGCCTGA
AGTCCCAGGACACCGCTGAGCTGTCCTTCGAGGACACCCGCGTTCCGAAGGAGAACCTGCTGGGCGAAGAGGGCGCCGCA
TTCGGCTACCTGCGCACCAACCTGGCTCAGGAGCGTCTGTCCATCGCCGTGGGGTCCATCGCTACCTCCCGCCGCGCATT
CGACCTGGTTTACAAGCACTCCCAGGATCGCAAGACCTTCGGTCAGCGCCTGATCGACCACCAGGCATACCGCTGGGAGC
TGGCCAAGATGGCTACCAACATCCAGGGCTCCCAGTCCTTCGTTGATGCCTGCATCATGGAGAAGGTCAACGGCACCCTG
GACGAGGTCACCGGTGCAATGGCTAAGTACCAGACCACCGAGCTGCAGATCGAGGTTGTAAACGAGGCCCTGCAGCTGCA
CGGCGGCTACGGCTTCATGCTGGAGTACCCGATCTCCACCCACTACCTGGACTCCCGCGTCCAGCCGATCTACGGCGGCC
CGAACGAGATCATGATCGAGATCATCTCTCGCCGCCTGGCCAAGGGCGAGAACTAA

Upstream 100 bases:

>100_bases
CCAACCTTGCCGCTGCTGGCGCTACTTGCGACGCTGACGAATCCAGCGATTCAGCCTTTTAGTAGTTCACGCAGCCATTG
CCTTGGTTTGAAAGGAACCC

Downstream 100 bases:

>100_bases
GGTCTAGCCTTACTCCCCCTTAAACTGCGGTGGTCGCTTTCCTAGGAAGGCGGCCACCGCTTCGCTATGGTCGGCGGTGT
TAAACAGGCGCAGCTGTGCC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKNFLPRNIFEEEHNMFREACADFVKAEIAPNVDRWHEQGYCDREMFQKAGQQGLLGMMAPEQFGGGGMENDYRFNAVLT
EELAKADSGSVIVGIQTINDLVIPYLQRFGNDDQKERFLKPLCAGEKIAALAMTEPGAGADLAGIRTFAKKDENGDYIVN
GAKTFISNGVQADFTLLVVVTNPEKGRAGVSMLIVEDGMEGYTKTGPLKKVGLKSQDTAELSFEDTRVPKENLLGEEGAA
FGYLRTNLAQERLSIAVGSIATSRRAFDLVYKHSQDRKTFGQRLIDHQAYRWELAKMATNIQGSQSFVDACIMEKVNGTL
DEVTGAMAKYQTTELQIEVVNEALQLHGGYGFMLEYPISTHYLDSRVQPIYGGPNEIMIEIISRRLAKGEN

Sequences:

>Translated_391_residues
MKNFLPRNIFEEEHNMFREACADFVKAEIAPNVDRWHEQGYCDREMFQKAGQQGLLGMMAPEQFGGGGMENDYRFNAVLT
EELAKADSGSVIVGIQTINDLVIPYLQRFGNDDQKERFLKPLCAGEKIAALAMTEPGAGADLAGIRTFAKKDENGDYIVN
GAKTFISNGVQADFTLLVVVTNPEKGRAGVSMLIVEDGMEGYTKTGPLKKVGLKSQDTAELSFEDTRVPKENLLGEEGAA
FGYLRTNLAQERLSIAVGSIATSRRAFDLVYKHSQDRKTFGQRLIDHQAYRWELAKMATNIQGSQSFVDACIMEKVNGTL
DEVTGAMAKYQTTELQIEVVNEALQLHGGYGFMLEYPISTHYLDSRVQPIYGGPNEIMIEIISRRLAKGEN
>Mature_391_residues
MKNFLPRNIFEEEHNMFREACADFVKAEIAPNVDRWHEQGYCDREMFQKAGQQGLLGMMAPEQFGGGGMENDYRFNAVLT
EELAKADSGSVIVGIQTINDLVIPYLQRFGNDDQKERFLKPLCAGEKIAALAMTEPGAGADLAGIRTFAKKDENGDYIVN
GAKTFISNGVQADFTLLVVVTNPEKGRAGVSMLIVEDGMEGYTKTGPLKKVGLKSQDTAELSFEDTRVPKENLLGEEGAA
FGYLRTNLAQERLSIAVGSIATSRRAFDLVYKHSQDRKTFGQRLIDHQAYRWELAKMATNIQGSQSFVDACIMEKVNGTL
DEVTGAMAKYQTTELQIEVVNEALQLHGGYGFMLEYPISTHYLDSRVQPIYGGPNEIMIEIISRRLAKGEN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=382, Percent_Identity=43.717277486911, Blast_Score=315, Evalue=6e-86,
Organism=Homo sapiens, GI7656849, Length=383, Percent_Identity=33.6814621409922, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI4557233, Length=380, Percent_Identity=30.2631578947368, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI4501859, Length=387, Percent_Identity=28.4237726098191, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI226958412, Length=386, Percent_Identity=31.8652849740933, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI226958414, Length=347, Percent_Identity=31.9884726224784, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI4557231, Length=382, Percent_Identity=30.8900523560209, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI187960098, Length=382, Percent_Identity=30.8900523560209, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI21361497, Length=375, Percent_Identity=29.3333333333333, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI4557235, Length=350, Percent_Identity=33.1428571428571, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI76496475, Length=350, Percent_Identity=33.1428571428571, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI4503943, Length=375, Percent_Identity=25.3333333333333, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI48976061, Length=356, Percent_Identity=25, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI211971008, Length=356, Percent_Identity=25, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38505218, Length=398, Percent_Identity=23.3668341708543, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7669494, Length=355, Percent_Identity=25.3521126760563, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI87081958, Length=354, Percent_Identity=27.9661016949153, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786223, Length=358, Percent_Identity=25.1396648044693, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI87082384, Length=305, Percent_Identity=27.8688524590164, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17505929, Length=379, Percent_Identity=31.9261213720317, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17551932, Length=383, Percent_Identity=31.331592689295, Blast_Score=213, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=34.5013477088949, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=29.8429319371728, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=31.413612565445, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17508101, Length=381, Percent_Identity=30.1837270341207, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=384, Percent_Identity=29.6875, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17570075, Length=374, Percent_Identity=30.7486631016043, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17534899, Length=367, Percent_Identity=29.9727520435967, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=33.8129496402878, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI71982178, Length=285, Percent_Identity=32.6315789473684, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17534353, Length=389, Percent_Identity=28.2776349614396, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=28.2722513089005, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32563615, Length=236, Percent_Identity=33.8983050847458, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71985192, Length=312, Percent_Identity=29.4871794871795, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17562446, Length=336, Percent_Identity=27.0833333333333, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=28.6307053941909, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=280, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI86563381, Length=280, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356377, Length=382, Percent_Identity=28.5340314136126, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24666513, Length=383, Percent_Identity=29.242819843342, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=29.3333333333333, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21355753, Length=387, Percent_Identity=30.4909560723514, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24660351, Length=385, Percent_Identity=30.3896103896104, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI281363737, Length=332, Percent_Identity=30.1204819277108, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=26.8929503916449, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 43368; Mature: 43368

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFLPRNIFEEEHNMFREACADFVKAEIAPNVDRWHEQGYCDREMFQKAGQQGLLGMMA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCCCEECCC
PEQFGGGGMENDYRFNAVLTEELAKADSGSVIVGIQTINDLVIPYLQRFGNDDQKERFLK
CHHCCCCCCCCCEEEHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHH
PLCAGEKIAALAMTEPGAGADLAGIRTFAKKDENGDYIVNGAKTFISNGVQADFTLLVVV
HHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEECHHHHHCCCCCCCEEEEEEE
TNPEKGRAGVSMLIVEDGMEGYTKTGPLKKVGLKSQDTAELSFEDTRVPKENLLGEEGAA
ECCCCCCCCEEEEEEECCCCCCCCCCCCHHCCCCCCCCCEECCCCCCCCHHHCCCCCCCC
FGYLRTNLAQERLSIAVGSIATSRRAFDLVYKHSQDRKTFGQRLIDHQAYRWELAKMATN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
IQGSQSFVDACIMEKVNGTLDEVTGAMAKYQTTELQIEVVNEALQLHGGYGFMLEYPIST
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEECCCCH
HYLDSRVQPIYGGPNEIMIEIISRRLAKGEN
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNFLPRNIFEEEHNMFREACADFVKAEIAPNVDRWHEQGYCDREMFQKAGQQGLLGMMA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCCCEECCC
PEQFGGGGMENDYRFNAVLTEELAKADSGSVIVGIQTINDLVIPYLQRFGNDDQKERFLK
CHHCCCCCCCCCEEEHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHH
PLCAGEKIAALAMTEPGAGADLAGIRTFAKKDENGDYIVNGAKTFISNGVQADFTLLVVV
HHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEECHHHHHCCCCCCCEEEEEEE
TNPEKGRAGVSMLIVEDGMEGYTKTGPLKKVGLKSQDTAELSFEDTRVPKENLLGEEGAA
ECCCCCCCCEEEEEEECCCCCCCCCCCCHHCCCCCCCCCEECCCCCCCCHHHCCCCCCCC
FGYLRTNLAQERLSIAVGSIATSRRAFDLVYKHSQDRKTFGQRLIDHQAYRWELAKMATN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
IQGSQSFVDACIMEKVNGTLDEVTGAMAKYQTTELQIEVVNEALQLHGGYGFMLEYPIST
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEECCCCH
HYLDSRVQPIYGGPNEIMIEIISRRLAKGEN
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]