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The map label for this gene is coaA

Identifier: 68536552

GI number: 68536552

Start: 1726472

End: 1727398

Strand: Direct

Name: coaA

Synonym: jk1466

Alternate gene names: 68536552

Gene position: 1726472-1727398 (Clockwise)

Preceding gene: 68536548

Following gene: 68536556

Centisome position: 70.11

GC content: 59.65

Gene sequence:

>927_bases
ATGGATGCTATGACTTCCCCCAGCCCTTACATTGAGCTGGACCGTACTCAGTGGCGCACCTTAAGAAAGTCGATGCCCCA
GGTCCTCACCGAAGATGAACTGGAACAGCTCCGCGGCATCGGCGATGAAATCGACCTGGAAGAAGTCTCCGAGGTCTACC
TCCCGCTGTCCCGCCTGATTTTCCTACGCGTCGAAGCGCACCGCAGGCTCAACGCCGCCACTGAAACGTTCCTCGGCGAG
GCAATGCCGCAGATTCCTTACATCATCGGCGTGTGCGGCTCCGTCGCTGTCGGCAAATCCACTACCGCTCGTGTTCTGCA
GGTTCTGCTGCAGCGCTGGGAGACAAACCCGCGGGTGGACCTCGTGACCACCGACGGGTTCCTTCTGCCCACCGCAGAGC
TCGAGCGCCGCAAGCTTATGCACCGCAAGGGTTTCCCGGAGTCCTACGACCAGGCGGAACTGCTGAGCTTCATCACTAAG
GTGAAGTCCGGCACCCAAAAGGTGCAGGCTCCTGTGTACTCCCACGAGGCATACGACCGAATTCCGGATCAGACCATCAC
CGTCGACCGCCCGGACATCCTCATCGTCGAGGGGCTGAACGTCTTGCAGACCGGCCCCACCCTCATGGTCTCCGACCTCT
TCGACTTTTCCGTCTACGTCGATGCCCGGCGCGAAGACATCGAGGATTGGTACATCGACCGCTTCCTACGTCTGAAGAAC
ACTGCGTTTAAGGATCCAGAGGCGCACTTCCACCACTTTGCCAACTTCAGCGATGAAGAGGCCACCGTGGTCGCCAGGGA
GATCTGGCAGACCGTGAACTTACCGAACCTGATGGAAAACATCCTCCCCACCCGCGTGCGTGCTTCCTTGGTTCTGCGCA
AGGGCCCGGACCACCTGGTGCAGAAAGTGCGGATGCGGAAGATCTAG

Upstream 100 bases:

>100_bases
ATCTGCATCACCATCATAGCGAGTGGCTGCGCCAGCCCACACCGAGCCCGCAGTGATCCCATTGCGATCCAATTTCACCT
TGCCCCAATTTCGGGGCACA

Downstream 100 bases:

>100_bases
CCCCCCGCGCGCTATCGCGGGCAGTTATCGCCCGCACCCCTATCGCCGGTTATCCCCCGCTTATAGCCCGAAGCGCCTGT
GCCGCTGCGAGTAGTCGCGC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDAMTSPSPYIELDRTQWRTLRKSMPQVLTEDELEQLRGIGDEIDLEEVSEVYLPLSRLIFLRVEAHRRLNAATETFLGE
AMPQIPYIIGVCGSVAVGKSTTARVLQVLLQRWETNPRVDLVTTDGFLLPTAELERRKLMHRKGFPESYDQAELLSFITK
VKSGTQKVQAPVYSHEAYDRIPDQTITVDRPDILIVEGLNVLQTGPTLMVSDLFDFSVYVDARREDIEDWYIDRFLRLKN
TAFKDPEAHFHHFANFSDEEATVVAREIWQTVNLPNLMENILPTRVRASLVLRKGPDHLVQKVRMRKI

Sequences:

>Translated_308_residues
MDAMTSPSPYIELDRTQWRTLRKSMPQVLTEDELEQLRGIGDEIDLEEVSEVYLPLSRLIFLRVEAHRRLNAATETFLGE
AMPQIPYIIGVCGSVAVGKSTTARVLQVLLQRWETNPRVDLVTTDGFLLPTAELERRKLMHRKGFPESYDQAELLSFITK
VKSGTQKVQAPVYSHEAYDRIPDQTITVDRPDILIVEGLNVLQTGPTLMVSDLFDFSVYVDARREDIEDWYIDRFLRLKN
TAFKDPEAHFHHFANFSDEEATVVAREIWQTVNLPNLMENILPTRVRASLVLRKGPDHLVQKVRMRKI
>Mature_308_residues
MDAMTSPSPYIELDRTQWRTLRKSMPQVLTEDELEQLRGIGDEIDLEEVSEVYLPLSRLIFLRVEAHRRLNAATETFLGE
AMPQIPYIIGVCGSVAVGKSTTARVLQVLLQRWETNPRVDLVTTDGFLLPTAELERRKLMHRKGFPESYDQAELLSFITK
VKSGTQKVQAPVYSHEAYDRIPDQTITVDRPDILIVEGLNVLQTGPTLMVSDLFDFSVYVDARREDIEDWYIDRFLRLKN
TAFKDPEAHFHHFANFSDEEATVVAREIWQTVNLPNLMENILPTRVRASLVLRKGPDHLVQKVRMRKI

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=307, Percent_Identity=52.7687296416938, Blast_Score=334, Evalue=4e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_CORJK (Q4JU68)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_251257.1
- ProteinModelPortal:   Q4JU68
- SMR:   Q4JU68
- STRING:   Q4JU68
- GeneID:   3432188
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk1466
- NMPDR:   fig|306537.3.peg.606
- eggNOG:   COG1072
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- ProtClustDB:   PRK05439
- BioCyc:   CJEI306537:JK1466-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 35476; Mature: 35476

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAMTSPSPYIELDRTQWRTLRKSMPQVLTEDELEQLRGIGDEIDLEEVSEVYLPLSRLI
CCCCCCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
FLRVEAHRRLNAATETFLGEAMPQIPYIIGVCGSVAVGKSTTARVLQVLLQRWETNPRVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHCCCCCEE
LVTTDGFLLPTAELERRKLMHRKGFPESYDQAELLSFITKVKSGTQKVQAPVYSHEAYDR
EEECCCEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHH
IPDQTITVDRPDILIVEGLNVLQTGPTLMVSDLFDFSVYVDARREDIEDWYIDRFLRLKN
CCCCEEECCCCCEEEECCCHHHHCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHH
TAFKDPEAHFHHFANFSDEEATVVAREIWQTVNLPNLMENILPTRVRASLVLRKGPDHLV
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
QKVRMRKI
HHHHHHCC
>Mature Secondary Structure
MDAMTSPSPYIELDRTQWRTLRKSMPQVLTEDELEQLRGIGDEIDLEEVSEVYLPLSRLI
CCCCCCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
FLRVEAHRRLNAATETFLGEAMPQIPYIIGVCGSVAVGKSTTARVLQVLLQRWETNPRVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHCCCCCEE
LVTTDGFLLPTAELERRKLMHRKGFPESYDQAELLSFITKVKSGTQKVQAPVYSHEAYDR
EEECCCEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHH
IPDQTITVDRPDILIVEGLNVLQTGPTLMVSDLFDFSVYVDARREDIEDWYIDRFLRLKN
CCCCEEECCCCCEEEECCCHHHHCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHH
TAFKDPEAHFHHFANFSDEEATVVAREIWQTVNLPNLMENILPTRVRASLVLRKGPDHLV
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
QKVRMRKI
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA