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The map label for this gene is xseA

Identifier: 68536536

GI number: 68536536

Start: 1708717

End: 1710027

Strand: Direct

Name: xseA

Synonym: jk1450

Alternate gene names: 68536536

Gene position: 1708717-1710027 (Clockwise)

Preceding gene: 68536534

Following gene: 68536537

Centisome position: 69.39

GC content: 61.48

Gene sequence:

>1311_bases
ATGAGCGTTCCTAACTCCCCTGAAGCCCCGTGGGCGGTCGGGCAGCTAAACGACCAGGTGAAGAACTGGATTCAAAGGCT
GGGGTTCATCTGGGTCGAAGGCCAGGTCACGCAGGTGAACATGAAGAGCACCTGGCGGTTTTCCTATATCACCCTCCGCG
ATGTGAACTTGGAAGCTTCAGTCTCCCTGACCGTGGAGACGAGCGCGCTGAAGAACTTGGCTACGCCGGTGAAGGACGGC
GACCGCATCGTCGTGCACGGCAAGCCGTCGTTCTATTCCAAGCGCGGCAGCTTTTCCCTGTGGGTCACGGAGATCCGGCA
GGTTGGTATCGGCCAGTTGCTAGCACAGATCGAACAGCTGAAAAAGGCCATGTTTGCCGAGGGACTTTTCGACCCTCGGC
TGAAGACTCCCCTTCCCTTCCTGCCCACCACCGTGGGATTGATTACTGGCCGTGGCTCGGCGGCGGAGCGGGACGTGATG
GAAGTAGCCAAGCGCCGCTGGCCGGCAGTGCGGTTTCGGGTGATTAATACAGCCGTCCAAGGCCCGAAAACGGTCCCGCA
GGTTGTCGATGCCCTGCAAGAATTGGAGCGAGACTCGGCGGTGGACGTAATCATCGTCGCCCGCGGCGGTGGTTCGGTGG
AAGACCTACTGCCGTTTTCCGAAGAAACACTGGTTCGCGAAGTATCCCGCCTGCGCACCCCAGTGGTGTCGGCCATTGGG
CACGAGCCAGACAATCCCTTGCTGGACTACGTAGCCGATGTGCGCGCAGCCACCCCCACGGACGCAGCCAAAACGGTGGT
TCCTGATGTAGTTCAGGAGCTGCGAATCATCAGCGAAGCGAGGCAGCGCGGCGCCGGTGCCCTGCGTAACTGGGTAGCAC
ACGAGCGTAAGGGACTGGCACAGATCCGCACCCGACCCGTGATGGCGGATCCTAGCCTCCCGGTCGCCCGCCAACAGGAC
ATCATCGCGGAAGCCCTGCAGCGTAAGGACCGCGCCCTGGGAGTGCACGTCCGTTCGCTGCGTTCCTCCATCGAGTCGCT
GAAGGCACAGGTCAATGCCTTGGGTCCATCACAGACCCTGGCGCGTGGGTATTCCATCGTGCAGGTCATCCCACGCGATA
AGTCAGGGGCCCAGGTGGTCACCACGGTGGATCAGGTTACCCCAGGTTCGCAGCTGCGCATCCGTGTCCCCGACGGATCC
ATCACGGCTGCGGCGATGGGCGTGCAGGCGGCACCTGGGGGCGTCATGAATAAAAACAGCAACACAACAGACAGCACCGA
CAACACCGAGAACGGCACAGGAGAGGCATAA

Upstream 100 bases:

>100_bases
AGTACCTGACAGTGCCCATCCCCTGCCCATCCCGTGCCCAACCGCTGCCCATCCCATGCCCAACCGCCGGTGTCCGGGCC
GTCATTTAAAATGCTTAACC

Downstream 100 bases:

>100_bases
GACAATGGCGGACAACACCAACAACGGCGCCAACAACACCGACAACGGCGAGCAGCAGAAGTTTCGCCCGCTCAACCAGC
TGAGTTACGAGCAGGCGCGC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSVPNSPEAPWAVGQLNDQVKNWIQRLGFIWVEGQVTQVNMKSTWRFSYITLRDVNLEASVSLTVETSALKNLATPVKDG
DRIVVHGKPSFYSKRGSFSLWVTEIRQVGIGQLLAQIEQLKKAMFAEGLFDPRLKTPLPFLPTTVGLITGRGSAAERDVM
EVAKRRWPAVRFRVINTAVQGPKTVPQVVDALQELERDSAVDVIIVARGGGSVEDLLPFSEETLVREVSRLRTPVVSAIG
HEPDNPLLDYVADVRAATPTDAAKTVVPDVVQELRIISEARQRGAGALRNWVAHERKGLAQIRTRPVMADPSLPVARQQD
IIAEALQRKDRALGVHVRSLRSSIESLKAQVNALGPSQTLARGYSIVQVIPRDKSGAQVVTTVDQVTPGSQLRIRVPDGS
ITAAAMGVQAAPGGVMNKNSNTTDSTDNTENGTGEA

Sequences:

>Translated_436_residues
MSVPNSPEAPWAVGQLNDQVKNWIQRLGFIWVEGQVTQVNMKSTWRFSYITLRDVNLEASVSLTVETSALKNLATPVKDG
DRIVVHGKPSFYSKRGSFSLWVTEIRQVGIGQLLAQIEQLKKAMFAEGLFDPRLKTPLPFLPTTVGLITGRGSAAERDVM
EVAKRRWPAVRFRVINTAVQGPKTVPQVVDALQELERDSAVDVIIVARGGGSVEDLLPFSEETLVREVSRLRTPVVSAIG
HEPDNPLLDYVADVRAATPTDAAKTVVPDVVQELRIISEARQRGAGALRNWVAHERKGLAQIRTRPVMADPSLPVARQQD
IIAEALQRKDRALGVHVRSLRSSIESLKAQVNALGPSQTLARGYSIVQVIPRDKSGAQVVTTVDQVTPGSQLRIRVPDGS
ITAAAMGVQAAPGGVMNKNSNTTDSTDNTENGTGEA
>Mature_435_residues
SVPNSPEAPWAVGQLNDQVKNWIQRLGFIWVEGQVTQVNMKSTWRFSYITLRDVNLEASVSLTVETSALKNLATPVKDGD
RIVVHGKPSFYSKRGSFSLWVTEIRQVGIGQLLAQIEQLKKAMFAEGLFDPRLKTPLPFLPTTVGLITGRGSAAERDVME
VAKRRWPAVRFRVINTAVQGPKTVPQVVDALQELERDSAVDVIIVARGGGSVEDLLPFSEETLVREVSRLRTPVVSAIGH
EPDNPLLDYVADVRAATPTDAAKTVVPDVVQELRIISEARQRGAGALRNWVAHERKGLAQIRTRPVMADPSLPVARQQDI
IAEALQRKDRALGVHVRSLRSSIESLKAQVNALGPSQTLARGYSIVQVIPRDKSGAQVVTTVDQVTPGSQLRIRVPDGSI
TAAAMGVQAAPGGVMNKNSNTTDSTDNTENGTGEA

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=453, Percent_Identity=30.4635761589404, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_CORJK (Q4JU84)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_251241.1
- STRING:   Q4JU84
- GeneID:   3433548
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk1450
- NMPDR:   fig|306537.3.peg.590
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   PWPVRTV
- ProtClustDB:   PRK00286
- BioCyc:   CJEI306537:JK1450-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 47372; Mature: 47240

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPNSPEAPWAVGQLNDQVKNWIQRLGFIWVEGQVTQVNMKSTWRFSYITLRDVNLEAS
CCCCCCCCCCEEHHHHHHHHHHHHHHHCEEEECCEEEEEECCCCEEEEEEEEEECCEEEE
VSLTVETSALKNLATPVKDGDRIVVHGKPSFYSKRGSFSLWVTEIRQVGIGQLLAQIEQL
EEEEEEHHHHHHHCCCCCCCCEEEEECCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KKAMFAEGLFDPRLKTPLPFLPTTVGLITGRGSAAERDVMEVAKRRWPAVRFRVINTAVQ
HHHHHHHCCCCCCCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHCCCHHEEHHHHHHHC
GPKTVPQVVDALQELERDSAVDVIIVARGGGSVEDLLPFSEETLVREVSRLRTPVVSAIG
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHC
HEPDNPLLDYVADVRAATPTDAAKTVVPDVVQELRIISEARQRGAGALRNWVAHERKGLA
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHH
QIRTRPVMADPSLPVARQQDIIAEALQRKDRALGVHVRSLRSSIESLKAQVNALGPSQTL
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ARGYSIVQVIPRDKSGAQVVTTVDQVTPGSQLRIRVPDGSITAAAMGVQAAPGGVMNKNS
HCCCEEEEEECCCCCCCEEEEEHHHCCCCCEEEEECCCCCEEHHHHCCCCCCCCCCCCCC
NTTDSTDNTENGTGEA
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVPNSPEAPWAVGQLNDQVKNWIQRLGFIWVEGQVTQVNMKSTWRFSYITLRDVNLEAS
CCCCCCCCCEEHHHHHHHHHHHHHHHCEEEECCEEEEEECCCCEEEEEEEEEECCEEEE
VSLTVETSALKNLATPVKDGDRIVVHGKPSFYSKRGSFSLWVTEIRQVGIGQLLAQIEQL
EEEEEEHHHHHHHCCCCCCCCEEEEECCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KKAMFAEGLFDPRLKTPLPFLPTTVGLITGRGSAAERDVMEVAKRRWPAVRFRVINTAVQ
HHHHHHHCCCCCCCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHCCCHHEEHHHHHHHC
GPKTVPQVVDALQELERDSAVDVIIVARGGGSVEDLLPFSEETLVREVSRLRTPVVSAIG
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHC
HEPDNPLLDYVADVRAATPTDAAKTVVPDVVQELRIISEARQRGAGALRNWVAHERKGLA
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHH
QIRTRPVMADPSLPVARQQDIIAEALQRKDRALGVHVRSLRSSIESLKAQVNALGPSQTL
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ARGYSIVQVIPRDKSGAQVVTTVDQVTPGSQLRIRVPDGSITAAAMGVQAAPGGVMNKNS
HCCCEEEEEECCCCCCCEEEEEHHHCCCCCEEEEECCCCCEEHHHHCCCCCCCCCCCCCC
NTTDSTDNTENGTGEA
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA