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The map label for this gene is cmtR [H]

Identifier: 68536523

GI number: 68536523

Start: 1695461

End: 1695820

Strand: Direct

Name: cmtR [H]

Synonym: jk1437

Alternate gene names: 68536523

Gene position: 1695461-1695820 (Clockwise)

Preceding gene: 68536521

Following gene: 68536524

Centisome position: 68.85

GC content: 66.39

Gene sequence:

>360_bases
ATGCTGACCATTGTTTCACGCCTCGACGTCATGAACCGGCTCGGCCGGGCCATGGCGGATCCGACGCGCTCCAGAATCCT
GATGACACTACTCGACGGCCCGAGCTACCCGGCCGTGCTTTCGCGCGACCTGGACCTGACCCGCTCGAACGTCTCGAACC
ACCTGACCTGCCTGCGCGACTGCGGCATCGTCGTCGCCGAGCCGGAGGGCCGCAAGACACGCTACGAAATCGCCGATCCG
CACCTCGCGGCAGCGCTCAACGCGCTGGTGAACGCGACGTTGGCTGTCGACGAAAACGCCCCGTGCATCGACCCTGAATG
CTCGGTGCCCGGCTGCGGCGAGAAGGGAGCGGACGCATGA

Upstream 100 bases:

>100_bases
TGCTATCCCATCGACTAATTCTTGCAGGTCGCAGGACCTTCGCGTAACTGTCAGTTCAGCGCATTTTGAATAGTTCAGCA
CACGATGTATTGTTCAGCAC

Downstream 100 bases:

>100_bases
GCTCGGCGTGTGGATGCGCACACGAACCCGCCACAGAGATCGAAGAACTCGATCGGCCATGGTGGAAGGACCCCGAGTTG
CTACTGCCGATCTTCTCCGG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MLTIVSRLDVMNRLGRAMADPTRSRILMTLLDGPSYPAVLSRDLDLTRSNVSNHLTCLRDCGIVVAEPEGRKTRYEIADP
HLAAALNALVNATLAVDENAPCIDPECSVPGCGEKGADA

Sequences:

>Translated_119_residues
MLTIVSRLDVMNRLGRAMADPTRSRILMTLLDGPSYPAVLSRDLDLTRSNVSNHLTCLRDCGIVVAEPEGRKTRYEIADP
HLAAALNALVNATLAVDENAPCIDPECSVPGCGEKGADA
>Mature_119_residues
MLTIVSRLDVMNRLGRAMADPTRSRILMTLLDGPSYPAVLSRDLDLTRSNVSNHLTCLRDCGIVVAEPEGRKTRYEIADP
HLAAALNALVNATLAVDENAPCIDPECSVPGCGEKGADA

Specific function: Metal-responsive transcriptional repressor for the cmt operon. Binding of cadmium or lead causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12732; Mature: 12732

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTIVSRLDVMNRLGRAMADPTRSRILMTLLDGPSYPAVLSRDLDLTRSNVSNHLTCLRD
CCHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHH
CGIVVAEPEGRKTRYEIADPHLAAALNALVNATLAVDENAPCIDPECSVPGCGEKGADA
CCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTIVSRLDVMNRLGRAMADPTRSRILMTLLDGPSYPAVLSRDLDLTRSNVSNHLTCLRD
CCHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHH
CGIVVAEPEGRKTRYEIADPHLAAALNALVNATLAVDENAPCIDPECSVPGCGEKGADA
CCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]