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The map label for this gene is era [H]

Identifier: 68535678

GI number: 68535678

Start: 733117

End: 734127

Strand: Direct

Name: era [H]

Synonym: jk0606

Alternate gene names: 68535678

Gene position: 733117-734127 (Clockwise)

Preceding gene: 68535677

Following gene: 68535679

Centisome position: 29.77

GC content: 64.69

Gene sequence:

>1011_bases
ATGACCATGAACGATCCTTATATCCCCGACGATCCCTTCGACCCGGGCGCGGGAATGCCCGAGGGGGCGGGCGTGGCGCC
CGAAGAAATGGAAGTGCCGGAGGAATACCGCGCACCCGAGGGCTTCCGCTCCGGGTTCGTCAGCTTCGTGGGGCGGCCGA
ACACCGGCAAGTCCACCCTGACGAACGCACTGGTGGGGGAGAAGATCGCCATCACCGCCGACCAGCCGGAAACCACGCGC
CACCCGATCCGCGGTATCGTCCACCGCGAAGATGCGCAGATCATTCTGGTGGACACTCCCGGCCTGCACCGGCCCCGCAC
GCTGCTTGGCGAGCGGCTGAACGAAGTGGTGAAGGAAACGTACTCGGATGTGGACGTCATCGCCATGTGCGTGCCCGCGG
ACGAGAAGATCGGCCCGGGGGACCGCTGGATTGTGGACGCCGTTCGTTCCGTCGCGCCGAAAACTCCGCTGATCGGTGTG
GTGACGAAGCTGGACAAGGTTTCCAAGGACCAGGTCGGTGCGCAACTGCTGGCACTGCACGAACTGCTGGACGGGGCGGA
CGTGGTGCCAGTTTCCTCCACCAAGCAGGTGCAGCTGGATGTGCTGCTGGACGTACTGCGCGACCAGCTGCCGGAAGGGC
CGAAGTTCTACCCGGACGACCACGTTACCGACGACGACCGCGATACCCGCATGGCCGAGCTGATCCGCGAAGCCGCGCTG
GAGGGGTTGCACGACGAGCTGCCGCACTCCGTGGCCGTGCAGATTGAGGAGGTCGTGCCGAACCCGCAGCGCGAGGGCGT
GCTGGACGTGCACGCGGTGATTTATGTGGAGCGCGAAGGCCAGAAGGCGATCTTGCGGGGCAAGGACGGGCGGCGACTGT
CGCGCATCGTCCACCGCTCCCGGTTGGAGATCGTGAAGATGTTGGACCAGAACATCTACCTGGACGTGCACATTAAGGTG
GCGAAGAACTGGCAGTCGGATCCGAAGCAGTTGGGGCGGATGGGATTCTAG

Upstream 100 bases:

>100_bases
GCCGTGGCGGCGTCCACAAGAAACAGCGCCCAAGATAAAGCCCAAGAGAAAACCCAAGATAAGAGCGCTAGCGATAAAGG
GCAGCAATAAGGGATACTTG

Downstream 100 bases:

>100_bases
CGGCTTGGTCTTGACCTGGGCCTGAACTGGGCTTGACCATCTTCTTGGTGCTTAGCCGGTGCGCGGAAGTGAAGTGCGAT
ACGTTGGTTTAGACTTTGAT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTMNDPYIPDDPFDPGAGMPEGAGVAPEEMEVPEEYRAPEGFRSGFVSFVGRPNTGKSTLTNALVGEKIAITADQPETTR
HPIRGIVHREDAQIILVDTPGLHRPRTLLGERLNEVVKETYSDVDVIAMCVPADEKIGPGDRWIVDAVRSVAPKTPLIGV
VTKLDKVSKDQVGAQLLALHELLDGADVVPVSSTKQVQLDVLLDVLRDQLPEGPKFYPDDHVTDDDRDTRMAELIREAAL
EGLHDELPHSVAVQIEEVVPNPQREGVLDVHAVIYVEREGQKAILRGKDGRRLSRIVHRSRLEIVKMLDQNIYLDVHIKV
AKNWQSDPKQLGRMGF

Sequences:

>Translated_336_residues
MTMNDPYIPDDPFDPGAGMPEGAGVAPEEMEVPEEYRAPEGFRSGFVSFVGRPNTGKSTLTNALVGEKIAITADQPETTR
HPIRGIVHREDAQIILVDTPGLHRPRTLLGERLNEVVKETYSDVDVIAMCVPADEKIGPGDRWIVDAVRSVAPKTPLIGV
VTKLDKVSKDQVGAQLLALHELLDGADVVPVSSTKQVQLDVLLDVLRDQLPEGPKFYPDDHVTDDDRDTRMAELIREAAL
EGLHDELPHSVAVQIEEVVPNPQREGVLDVHAVIYVEREGQKAILRGKDGRRLSRIVHRSRLEIVKMLDQNIYLDVHIKV
AKNWQSDPKQLGRMGF
>Mature_335_residues
TMNDPYIPDDPFDPGAGMPEGAGVAPEEMEVPEEYRAPEGFRSGFVSFVGRPNTGKSTLTNALVGEKIAITADQPETTRH
PIRGIVHREDAQIILVDTPGLHRPRTLLGERLNEVVKETYSDVDVIAMCVPADEKIGPGDRWIVDAVRSVAPKTPLIGVV
TKLDKVSKDQVGAQLLALHELLDGADVVPVSSTKQVQLDVLLDVLRDQLPEGPKFYPDDHVTDDDRDTRMAELIREAALE
GLHDELPHSVAVQIEEVVPNPQREGVLDVHAVIYVEREGQKAILRGKDGRRLSRIVHRSRLEIVKMLDQNIYLDVHIKVA
KNWQSDPKQLGRMGF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=296, Percent_Identity=35.472972972973, Blast_Score=178, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 37257; Mature: 37126

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNDPYIPDDPFDPGAGMPEGAGVAPEEMEVPEEYRAPEGFRSGFVSFVGRPNTGKSTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHCCCCHHHHHHHHHCCCCCCCHHHH
TNALVGEKIAITADQPETTRHPIRGIVHREDAQIILVDTPGLHRPRTLLGERLNEVVKET
HHHHHCCEEEEECCCCCCHHHHHHHHEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
YSDVDVIAMCVPADEKIGPGDRWIVDAVRSVAPKTPLIGVVTKLDKVSKDQVGAQLLALH
HCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELLDGADVVPVSSTKQVQLDVLLDVLRDQLPEGPKFYPDDHVTDDDRDTRMAELIREAAL
HHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
EGLHDELPHSVAVQIEEVVPNPQREGVLDVHAVIYVEREGQKAILRGKDGRRLSRIVHRS
HHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCEEEEECCCCHHHHHHHHHH
RLEIVKMLDQNIYLDVHIKVAKNWQSDPKQLGRMGF
HHHHHHHHCCCEEEEEEEEEECCCCCCHHHHCCCCC
>Mature Secondary Structure 
TMNDPYIPDDPFDPGAGMPEGAGVAPEEMEVPEEYRAPEGFRSGFVSFVGRPNTGKSTL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHCCCCHHHHHHHHHCCCCCCCHHHH
TNALVGEKIAITADQPETTRHPIRGIVHREDAQIILVDTPGLHRPRTLLGERLNEVVKET
HHHHHCCEEEEECCCCCCHHHHHHHHEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
YSDVDVIAMCVPADEKIGPGDRWIVDAVRSVAPKTPLIGVVTKLDKVSKDQVGAQLLALH
HCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELLDGADVVPVSSTKQVQLDVLLDVLRDQLPEGPKFYPDDHVTDDDRDTRMAELIREAAL
HHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
EGLHDELPHSVAVQIEEVVPNPQREGVLDVHAVIYVEREGQKAILRGKDGRRLSRIVHRS
HHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCEEEEECCCCHHHHHHHHHH
RLEIVKMLDQNIYLDVHIKVAKNWQSDPKQLGRMGF
HHHHHHHHCCCEEEEEEEEEECCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14602910 [H]