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The map label for this gene is ybeX [C]

Identifier: 68535677

GI number: 68535677

Start: 731679

End: 733106

Strand: Direct

Name: ybeX [C]

Synonym: jk0605

Alternate gene names: 68535677

Gene position: 731679-733106 (Clockwise)

Preceding gene: 68535676

Following gene: 68535678

Centisome position: 29.71

GC content: 62.32

Gene sequence:

>1428_bases
ATGACGATCGACATCCCCTTATCCATCCCATTTGCGATCCTTGCGCTCTTCTTAGGCGGTGTGCTGTCGCTGGTGGAAAC
GGCAGTGTCATCGCTCTCCGCAGCGCGGGTGGAGAACCTTGTGAAGGAGGATCGCCCGGGTGCTGCCCGGTTGGAACGGG
TGCTCGAGGGGCGGGCTGGTCACATCAACCTGTTGGTGCTGCTCCGCACCATTTGCGAGGTCTCCGGCGCAGTGCTGGCT
GCCGCCGCCTGCGTAGAGCTGATGGGTTCGCGCGGCTGGGCATTCGCCACCGCCATCGTCATCGTCACGCTGCTGACATT
CATCCTGATCGGCGTGCTCTCCCGCACGCTCGGTCGACAGAACCCGTACACCATTAGTCTGGCGACCGCCCCGATTCTGC
TGGGACTATCCAAGCTGCTGGGACCCATCGCAAAGTTGCTGGTCGGTGCCGGTAATGTGCTGACGCCCGGCCGGGGTTTC
CGCAACGGTCCCTTCGCCTCCGAAATTGAGCTGCGCGAAATGGTGGACATCGCCTCCGAACGCGGCGTCGTGGAGATGGA
CGAGAGGCGGATGATCCAATCCGTCTTTGACCTCGCCGACACCTCGGCGCGCTCCGTAATGGTGCCGCGGCCAGAGATGG
TGTGGATCGAGGCGGATAAGACCGCCGGCCAGGCCACCAGCCTGTGCGTGCGCACCGGTCTTTCCCGGCTGCCCGTGGTG
GGGGATGACGTGGACGACATTGTGGGCGTCATTTACCTCAAAGACCTCATTGCCGAGACCTATCACATGACCGACGGCGG
CAGCTCCATCCGCGTGCGGGACTGCATGCGGCCCGCCGTGTTCGTACCGGATTCGAAAAAACTGGATGACCTGCTGGAGG
ACATGCAGCGCGACCAGATTCACATTGCCATGCTTATCGACGAATACGGTGCAGTGGCGGGGCTGATTTCCATCGAGGAC
ATCCTGGAGGAAATCGTCGGCGAGATCACCGACGAATACGACACGTCGGAGCAGGCGCCGATAGAGCCCCTGGAGGACGG
CAGCTACCGAGTACAGGCGCGTCTGTCGCTGGAGGAACTCGAGGAGCTATTCGAGGACGTGGAGTTCAGCGAAGAGCAGC
ACGAGGAAGTGGATACCGTCTACGGCCTCGGAGCCTTCGAGCTGGGCAGGGTGCCGATCCCAGGGGCGGAAATTTCCACC
ACCGGTCTGCACCTCCGCTACGAGGGCGGGCGCGACCGCCGTGGGCGCGTGAAGATCCGTACCGCCGTGGTGACCCGCGA
GAAGCAGGTGGAAGGCACTGGTGATGCTGGCCACGATGGTGAGGTGGTGGAAGGGATGGCCGTGGCGGCGTCCACAAGAA
ACAGCGCCCAAGATAAAGCCCAAGAGAAAACCCAAGATAAGAGCGCTAGCGATAAAGGGCAGCAATAA

Upstream 100 bases:

>100_bases
GGAGGAGCGCGGCGTGAGCTTCGCTCCGAAGCCGACTGGTGCCGGGGCCTTCCCCAGTGCTGCGGACCGCGACGACACTC
AAAACTAGAAGCTTCGAAAG

Downstream 100 bases:

>100_bases
GGGATACTTGATGACCATGAACGATCCTTATATCCCCGACGATCCCTTCGACCCGGGCGCGGGAATGCCCGAGGGGGCGG
GCGTGGCGCCCGAAGAAATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTIDIPLSIPFAILALFLGGVLSLVETAVSSLSAARVENLVKEDRPGAARLERVLEGRAGHINLLVLLRTICEVSGAVLA
AAACVELMGSRGWAFATAIVIVTLLTFILIGVLSRTLGRQNPYTISLATAPILLGLSKLLGPIAKLLVGAGNVLTPGRGF
RNGPFASEIELREMVDIASERGVVEMDERRMIQSVFDLADTSARSVMVPRPEMVWIEADKTAGQATSLCVRTGLSRLPVV
GDDVDDIVGVIYLKDLIAETYHMTDGGSSIRVRDCMRPAVFVPDSKKLDDLLEDMQRDQIHIAMLIDEYGAVAGLISIED
ILEEIVGEITDEYDTSEQAPIEPLEDGSYRVQARLSLEELEELFEDVEFSEEQHEEVDTVYGLGAFELGRVPIPGAEIST
TGLHLRYEGGRDRRGRVKIRTAVVTREKQVEGTGDAGHDGEVVEGMAVAASTRNSAQDKAQEKTQDKSASDKGQQ

Sequences:

>Translated_475_residues
MTIDIPLSIPFAILALFLGGVLSLVETAVSSLSAARVENLVKEDRPGAARLERVLEGRAGHINLLVLLRTICEVSGAVLA
AAACVELMGSRGWAFATAIVIVTLLTFILIGVLSRTLGRQNPYTISLATAPILLGLSKLLGPIAKLLVGAGNVLTPGRGF
RNGPFASEIELREMVDIASERGVVEMDERRMIQSVFDLADTSARSVMVPRPEMVWIEADKTAGQATSLCVRTGLSRLPVV
GDDVDDIVGVIYLKDLIAETYHMTDGGSSIRVRDCMRPAVFVPDSKKLDDLLEDMQRDQIHIAMLIDEYGAVAGLISIED
ILEEIVGEITDEYDTSEQAPIEPLEDGSYRVQARLSLEELEELFEDVEFSEEQHEEVDTVYGLGAFELGRVPIPGAEIST
TGLHLRYEGGRDRRGRVKIRTAVVTREKQVEGTGDAGHDGEVVEGMAVAASTRNSAQDKAQEKTQDKSASDKGQQ
>Mature_474_residues
TIDIPLSIPFAILALFLGGVLSLVETAVSSLSAARVENLVKEDRPGAARLERVLEGRAGHINLLVLLRTICEVSGAVLAA
AACVELMGSRGWAFATAIVIVTLLTFILIGVLSRTLGRQNPYTISLATAPILLGLSKLLGPIAKLLVGAGNVLTPGRGFR
NGPFASEIELREMVDIASERGVVEMDERRMIQSVFDLADTSARSVMVPRPEMVWIEADKTAGQATSLCVRTGLSRLPVVG
DDVDDIVGVIYLKDLIAETYHMTDGGSSIRVRDCMRPAVFVPDSKKLDDLLEDMQRDQIHIAMLIDEYGAVAGLISIEDI
LEEIVGEITDEYDTSEQAPIEPLEDGSYRVQARLSLEELEELFEDVEFSEEQHEEVDTVYGLGAFELGRVPIPGAEISTT
GLHLRYEGGRDRRGRVKIRTAVVTREKQVEGTGDAGHDGEVVEGMAVAASTRNSAQDKAQEKTQDKSASDKGQQ

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=389, Percent_Identity=25.9640102827763, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI94681046, Length=177, Percent_Identity=28.2485875706215, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786879, Length=245, Percent_Identity=33.8775510204082, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI145693175, Length=381, Percent_Identity=23.6220472440945, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI87082033, Length=214, Percent_Identity=28.5046728971963, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788119, Length=234, Percent_Identity=28.2051282051282, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790664, Length=308, Percent_Identity=20.4545454545455, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 51439; Mature: 51308

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDIPLSIPFAILALFLGGVLSLVETAVSSLSAARVENLVKEDRPGAARLERVLEGRAG
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
HINLLVLLRTICEVSGAVLAAAACVELMGSRGWAFATAIVIVTLLTFILIGVLSRTLGRQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPYTISLATAPILLGLSKLLGPIAKLLVGAGNVLTPGRGFRNGPFASEIELREMVDIASE
CCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
RGVVEMDERRMIQSVFDLADTSARSVMVPRPEMVWIEADKTAGQATSLCVRTGLSRLPVV
CCCEEHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHCHHHCCCC
GDDVDDIVGVIYLKDLIAETYHMTDGGSSIRVRDCMRPAVFVPDSKKLDDLLEDMQRDQI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCCEECCCCHHHHHHHHHHHHCCE
HIAMLIDEYGAVAGLISIEDILEEIVGEITDEYDTSEQAPIEPLEDGSYRVQARLSLEEL
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHH
EELFEDVEFSEEQHEEVDTVYGLGAFELGRVPIPGAEISTTGLHLRYEGGRDRRGRVKIR
HHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCEEECEEEEEECCCCCCCCCEEEE
TAVVTREKQVEGTGDAGHDGEVVEGMAVAASTRNSAQDKAQEKTQDKSASDKGQQ
EEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TIDIPLSIPFAILALFLGGVLSLVETAVSSLSAARVENLVKEDRPGAARLERVLEGRAG
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
HINLLVLLRTICEVSGAVLAAAACVELMGSRGWAFATAIVIVTLLTFILIGVLSRTLGRQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPYTISLATAPILLGLSKLLGPIAKLLVGAGNVLTPGRGFRNGPFASEIELREMVDIASE
CCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
RGVVEMDERRMIQSVFDLADTSARSVMVPRPEMVWIEADKTAGQATSLCVRTGLSRLPVV
CCCEEHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHCHHHCCCC
GDDVDDIVGVIYLKDLIAETYHMTDGGSSIRVRDCMRPAVFVPDSKKLDDLLEDMQRDQI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCCEECCCCHHHHHHHHHHHHCCE
HIAMLIDEYGAVAGLISIEDILEEIVGEITDEYDTSEQAPIEPLEDGSYRVQARLSLEEL
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHHH
EELFEDVEFSEEQHEEVDTVYGLGAFELGRVPIPGAEISTTGLHLRYEGGRDRRGRVKIR
HHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCEEECEEEEEECCCCCCCCCEEEE
TAVVTREKQVEGTGDAGHDGEVVEGMAVAASTRNSAQDKAQEKTQDKSASDKGQQ
EEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]