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The map label for this gene is fkb [C]

Identifier: 68535497

GI number: 68535497

Start: 512568

End: 512927

Strand: Direct

Name: fkb [C]

Synonym: jk0427

Alternate gene names: 68535497

Gene position: 512568-512927 (Clockwise)

Preceding gene: 68535496

Following gene: 68535500

Centisome position: 20.81

GC content: 64.17

Gene sequence:

>360_bases
ATGAGCAAACCGCAGATCGACCTCTCGAACGGCCCCGCACCGAAGGACCTGGTGATTGAAGACCTGGTGATCGGTGATGG
CGCAGAGGCCGTACCGGGCGGCATGGTGGAGGTGCACTACGTGGGAGTGGACTTCGCGACCGGCGAGGAGTTCGACTCTT
CCTGGGATCGCGGCGAGTCCATCGAGTTCCCCCTTTCCGGCCTGATCGAGGGCTGGCAGGAGGGTATCCCGGGCATGCGC
GCCGGTGGTCGCCGCAAGCTGACTATTCCCCCGGAGAAGGCGTACGGCCCGGCCGGTATGGGCCACCCCCTGTCTGGCCG
TACGCTGGTCTTCATTATTGACCTGATCGCCGTGAACTAA

Upstream 100 bases:

>100_bases
CCTCGGTGTGGCTGCGCGAAGCGCATGCCCCCAAGGGGGCTTTTCGCGTTTTGCTAGGGTGGAGCCTCGAGAAGCTATCA
GTTTTCGAAGGAGACTTCCC

Downstream 100 bases:

>100_bases
AGCGGTTAGGCGCCCTTTAGCGCCTTGGCCCAGCTCATCTTCTTACCGTTGTTCAGAATGGAATTGCGGTAGACGCGGGC
CACCAGCAGAATCACCAGAA

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MSKPQIDLSNGPAPKDLVIEDLVIGDGAEAVPGGMVEVHYVGVDFATGEEFDSSWDRGESIEFPLSGLIEGWQEGIPGMR
AGGRRKLTIPPEKAYGPAGMGHPLSGRTLVFIIDLIAVN

Sequences:

>Translated_119_residues
MSKPQIDLSNGPAPKDLVIEDLVIGDGAEAVPGGMVEVHYVGVDFATGEEFDSSWDRGESIEFPLSGLIEGWQEGIPGMR
AGGRRKLTIPPEKAYGPAGMGHPLSGRTLVFIIDLIAVN
>Mature_118_residues
SKPQIDLSNGPAPKDLVIEDLVIGDGAEAVPGGMVEVHYVGVDFATGEEFDSSWDRGESIEFPLSGLIEGWQEGIPGMRA
GGRRKLTIPPEKAYGPAGMGHPLSGRTLVFIIDLIAVN

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI87082390, Length=101, Percent_Identity=44.5544554455446, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI1789745, Length=103, Percent_Identity=41.747572815534, Blast_Score=64, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320727, Length=108, Percent_Identity=40.7407407407407, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324194, Length=108, Percent_Identity=38.8888888888889, Blast_Score=64, Evalue=6e-12,
Organism=Drosophila melanogaster, GI281363946, Length=89, Percent_Identity=40.4494382022472, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17352457, Length=89, Percent_Identity=40.4494382022472, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647110, Length=118, Percent_Identity=38.9830508474576, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 12616; Mature: 12485

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPQIDLSNGPAPKDLVIEDLVIGDGAEAVPGGMVEVHYVGVDFATGEEFDSSWDRGES
CCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCC
IEFPLSGLIEGWQEGIPGMRAGGRRKLTIPPEKAYGPAGMGHPLSGRTLVFIIDLIAVN
CCCCHHHHHHHHHHCCCCCCCCCEEEEECCCHHCCCCCCCCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure 
SKPQIDLSNGPAPKDLVIEDLVIGDGAEAVPGGMVEVHYVGVDFATGEEFDSSWDRGES
CCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCC
IEFPLSGLIEGWQEGIPGMRAGGRRKLTIPPEKAYGPAGMGHPLSGRTLVFIIDLIAVN
CCCCHHHHHHHHHHCCCCCCCCCEEEEECCCHHCCCCCCCCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7522844; 12948626 [H]