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The map label for this gene is cat1 [H]

Identifier: 68535450

GI number: 68535450

Start: 457524

End: 459029

Strand: Direct

Name: cat1 [H]

Synonym: jk0384

Alternate gene names: 68535450

Gene position: 457524-459029 (Clockwise)

Preceding gene: 68535446

Following gene: 68535451

Centisome position: 18.58

GC content: 60.89

Gene sequence:

>1506_bases
ATGTCTGAGCGCATCGCCAACGAGTTCTACAGGTCCAAGGTCATGTCCGCCGACGAGGCGGCGCAGTTCATCAACCACGG
CGACAAGATCGGCATGTCCGGCTTCACGGGAGCGGGCTACCCCAAGGCGCTGCCGACGGCCATCGCCGAGAAGGCTAAGG
AACTGCACGGTCGCGGTGAGAACTTCCAGATTGACCTCTTCACTGGCGCCTCCACCGCACCTGACTGCGACGGCGTGCTG
GCCGAGGCTGATGCTGTGCGCTACCGTACCCCCTACGCTTCCGACCCGGTGATGCGCAAGAAGATCAATGCCGGCGAGAT
TAAGTACCAAGATATCCACCTCTCCCACCTCGGCCAGCAGGTCGAGGAAGGCTTCTTCGGCCAGCTGGATGTAGCTGTCG
TGGAAGCTGTGCGCATCGATGAGGCGGGCAACATCATCCCGTCCTCGGCAGTCGGCAATAACGTGGAGTACCTCAACTCC
GCCCGCAAGATCATCATCGAGGTCAATGAATGGCAGTCCCTCGACCTGGAGGGCATGCACGACATCTACAAGATCCAGGA
CCTGCCGAACCGCACCCCGATCCCGATCAACCGCCCCGGCGACCGCATCGGCACGCCGTACATTCCGGTGGATCAGAATA
AGGTCGTGGCCGTGGTGAAGACCAACGCCGAAGACCGCAACGCGCCGTTCAAGCCGACCGATGAGGTCTCCGAAAAGATT
GCCGGGCACTTCCTGGATCTTCTGGAGGGCGAGGTCGAGGCTGGTCGCCTGACCTACGACGGCTACATCATGCAGTCTGG
CGTGGGCAACGTGCCGAATGCTGTGATGGCGGGGCTTCTGGACTCCAAGTTCGAGAACATCCAGGCCTACACTGAGGTGA
TCCAGGACGGCATGCTGGACCTCATCGACAACGGCAAGATGACCGTTGCCTCCGCAACCTCCTTCGCGTTGTCCCCGGAA
TACGCAAAGAAGATGAACGATGAGGCGAAGCGCTACCGCGAGCACATCGTCCTGCGCCCACAGCAGATCTCCAACCACCC
GGAGGTCATCCGTCGCACGGGCCTGATCGCCTCCAACGGCATGATCGGCTGTGATATCTACGGCAACGTGAACTCCACGA
ACGTGTCTGGTTCGCGCATCATGAATGGCATCGGCGGCTCCGGTGATTTCACGCGCAACGCCTTCCTATCGACCTTCATC
TCCCCGTCAACGGCCAAGGACGGCGCCATTTCCGCCATCGTGCCCTTTGCCTCCCATATTGACCACACAGAGCACGACGT
GATGGTCATCATCACGGAGTACGGCTACGCAGACCTGCGTGGTCTGGCGCCGCGTGATCGCGTGCCGAAGATTATCTCCG
TTGCGCACCCGGACTACCGTCCGCTGCTGGAGGAGTACTACGAGCGTGCCTGCGCCGAGGGCAACCACCTGCAGACCCCG
CACGATCTGAAGACCGCCTTCAGCTTCCACATCAACCTGGCGGAAAAGGGCTCAATGAAGGGCTAG

Upstream 100 bases:

>100_bases
GTTCAACAATAGGCTGGAGGGTGAGGGCGATCTACGTCACATTTATGTAGGCTGAAGAAAGAAGCGGAGAAACCGCTAAA
CAGCTATGGAGGAGGAACCG

Downstream 100 bases:

>100_bases
CGCTGGCGCAAGTTCTGGTGCCGGCACATTGCCGGCGCCGGTACTAGGGGGCAATTTTCCGCTTCGGTGAGGCTTTAGAT
AGAATGCTCCCGTTGGGCCT

Product: succinyl-CoA:coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MSERIANEFYRSKVMSADEAAQFINHGDKIGMSGFTGAGYPKALPTAIAEKAKELHGRGENFQIDLFTGASTAPDCDGVL
AEADAVRYRTPYASDPVMRKKINAGEIKYQDIHLSHLGQQVEEGFFGQLDVAVVEAVRIDEAGNIIPSSAVGNNVEYLNS
ARKIIIEVNEWQSLDLEGMHDIYKIQDLPNRTPIPINRPGDRIGTPYIPVDQNKVVAVVKTNAEDRNAPFKPTDEVSEKI
AGHFLDLLEGEVEAGRLTYDGYIMQSGVGNVPNAVMAGLLDSKFENIQAYTEVIQDGMLDLIDNGKMTVASATSFALSPE
YAKKMNDEAKRYREHIVLRPQQISNHPEVIRRTGLIASNGMIGCDIYGNVNSTNVSGSRIMNGIGGSGDFTRNAFLSTFI
SPSTAKDGAISAIVPFASHIDHTEHDVMVIITEYGYADLRGLAPRDRVPKIISVAHPDYRPLLEEYYERACAEGNHLQTP
HDLKTAFSFHINLAEKGSMKG

Sequences:

>Translated_501_residues
MSERIANEFYRSKVMSADEAAQFINHGDKIGMSGFTGAGYPKALPTAIAEKAKELHGRGENFQIDLFTGASTAPDCDGVL
AEADAVRYRTPYASDPVMRKKINAGEIKYQDIHLSHLGQQVEEGFFGQLDVAVVEAVRIDEAGNIIPSSAVGNNVEYLNS
ARKIIIEVNEWQSLDLEGMHDIYKIQDLPNRTPIPINRPGDRIGTPYIPVDQNKVVAVVKTNAEDRNAPFKPTDEVSEKI
AGHFLDLLEGEVEAGRLTYDGYIMQSGVGNVPNAVMAGLLDSKFENIQAYTEVIQDGMLDLIDNGKMTVASATSFALSPE
YAKKMNDEAKRYREHIVLRPQQISNHPEVIRRTGLIASNGMIGCDIYGNVNSTNVSGSRIMNGIGGSGDFTRNAFLSTFI
SPSTAKDGAISAIVPFASHIDHTEHDVMVIITEYGYADLRGLAPRDRVPKIISVAHPDYRPLLEEYYERACAEGNHLQTP
HDLKTAFSFHINLAEKGSMKG
>Mature_500_residues
SERIANEFYRSKVMSADEAAQFINHGDKIGMSGFTGAGYPKALPTAIAEKAKELHGRGENFQIDLFTGASTAPDCDGVLA
EADAVRYRTPYASDPVMRKKINAGEIKYQDIHLSHLGQQVEEGFFGQLDVAVVEAVRIDEAGNIIPSSAVGNNVEYLNSA
RKIIIEVNEWQSLDLEGMHDIYKIQDLPNRTPIPINRPGDRIGTPYIPVDQNKVVAVVKTNAEDRNAPFKPTDEVSEKIA
GHFLDLLEGEVEAGRLTYDGYIMQSGVGNVPNAVMAGLLDSKFENIQAYTEVIQDGMLDLIDNGKMTVASATSFALSPEY
AKKMNDEAKRYREHIVLRPQQISNHPEVIRRTGLIASNGMIGCDIYGNVNSTNVSGSRIMNGIGGSGDFTRNAFLSTFIS
PSTAKDGAISAIVPFASHIDHTEHDVMVIITEYGYADLRGLAPRDRVPKIISVAHPDYRPLLEEYYERACAEGNHLQTPH
DLKTAFSFHINLAEKGSMKG

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=489, Percent_Identity=45.8077709611452, Blast_Score=414, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17538151, Length=392, Percent_Identity=26.530612244898, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32563853, Length=236, Percent_Identity=30.0847457627119, Blast_Score=79, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319456, Length=515, Percent_Identity=41.3592233009709, Blast_Score=388, Evalue=1e-108,
Organism=Drosophila melanogaster, GI21358615, Length=239, Percent_Identity=27.1966527196653, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 54933; Mature: 54801

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERIANEFYRSKVMSADEAAQFINHGDKIGMSGFTGAGYPKALPTAIAEKAKELHGRGE
CCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
NFQIDLFTGASTAPDCDGVLAEADAVRYRTPYASDPVMRKKINAGEIKYQDIHLSHLGQQ
CEEEEEEECCCCCCCCCCHHHCCCHHEECCCCCCCCHHHHCCCCCCEEEEEEEHHHHHHH
VEEGFFGQLDVAVVEAVRIDEAGNIIPSSAVGNNVEYLNSARKIIIEVNEWQSLDLEGMH
HHHCCCCCHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHCCEEEEEEECCCCCCCCCCHH
DIYKIQDLPNRTPIPINRPGDRIGTPYIPVDQNKVVAVVKTNAEDRNAPFKPTDEVSEKI
HHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHH
AGHFLDLLEGEVEAGRLTYDGYIMQSGVGNVPNAVMAGLLDSKFENIQAYTEVIQDGMLD
HHHHHHHHCCCCCCCEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDNGKMTVASATSFALSPEYAKKMNDEAKRYREHIVLRPQQISNHPEVIRRTGLIASNG
HHCCCCEEEEECCHHCCCHHHHHHCCHHHHHHHHHEEECHHHHCCCHHHHHHHCCEECCC
MIGCDIYGNVNSTNVSGSRIMNGIGGSGDFTRNAFLSTFISPSTAKDGAISAIVPFASHI
EEEEEEECCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
DHTEHDVMVIITEYGYADLRGLAPRDRVPKIISVAHPDYRPLLEEYYERACAEGNHLQTP
CCCCCCEEEEEECCCCHHHCCCCCCCCCCHHEEECCCCHHHHHHHHHHHHHCCCCCCCCC
HDLKTAFSFHINLAEKGSMKG
HHHHHEEEEEEEECCCCCCCC
>Mature Secondary Structure 
SERIANEFYRSKVMSADEAAQFINHGDKIGMSGFTGAGYPKALPTAIAEKAKELHGRGE
CHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
NFQIDLFTGASTAPDCDGVLAEADAVRYRTPYASDPVMRKKINAGEIKYQDIHLSHLGQQ
CEEEEEEECCCCCCCCCCHHHCCCHHEECCCCCCCCHHHHCCCCCCEEEEEEEHHHHHHH
VEEGFFGQLDVAVVEAVRIDEAGNIIPSSAVGNNVEYLNSARKIIIEVNEWQSLDLEGMH
HHHCCCCCHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHCCEEEEEEECCCCCCCCCCHH
DIYKIQDLPNRTPIPINRPGDRIGTPYIPVDQNKVVAVVKTNAEDRNAPFKPTDEVSEKI
HHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHH
AGHFLDLLEGEVEAGRLTYDGYIMQSGVGNVPNAVMAGLLDSKFENIQAYTEVIQDGMLD
HHHHHHHHCCCCCCCEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIDNGKMTVASATSFALSPEYAKKMNDEAKRYREHIVLRPQQISNHPEVIRRTGLIASNG
HHCCCCEEEEECCHHCCCHHHHHHCCHHHHHHHHHEEECHHHHCCCHHHHHHHCCEECCC
MIGCDIYGNVNSTNVSGSRIMNGIGGSGDFTRNAFLSTFISPSTAKDGAISAIVPFASHI
EEEEEEECCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
DHTEHDVMVIITEYGYADLRGLAPRDRVPKIISVAHPDYRPLLEEYYERACAEGNHLQTP
CCCCCCEEEEEECCCCHHHCCCCCCCCCCHHEEECCCCHHHHHHHHHHHHHCCCCCCCCC
HDLKTAFSFHINLAEKGSMKG
HHHHHEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]