Click here to switch to the map view.

The map label for this gene is gntK [H]

Identifier: 68535446

GI number: 68535446

Start: 454707

End: 455258

Strand: Direct

Name: gntK [H]

Synonym: jk0381

Alternate gene names: 68535446

Gene position: 454707-455258 (Clockwise)

Preceding gene: 68535445

Following gene: 68535450

Centisome position: 18.47

GC content: 63.04

Gene sequence:

>552_bases
ATGTCTAGCCAAGAGACTCCGGCAACCCTCCACGTCGTCGTGATGGGGGTCAGTGGCAGTGGCAAGACCACCCTGGCGCG
CGCTTTTGCCGAGAAGACCGGCTGGCAGTTGCAGGAAGCCGACGATCTGCACCCTGAGGGTGCGCTGGAGATCCTGCAAG
ACGGCAAGCTCCCGCCGGAGGAGGGGCGCCGAACGTGGCTAAGGATTGTCCGCGATTGGATTGCGGATGAGGCAGCCCAG
GGTAACAACACTGTCACCGCTTGTACCGCGCTGCGCATCGACCACCGCGAGATTCTCAATGACGCGGGCGAGAACGCGAC
CGTGTTCTACGTGCACCTGTACGGTACCGAGGATGTCCTCGCGGAGCGGATGAAGAACCGTGTAGGAGACGCGGACATGC
CACGCGAACTGCTGACCGCGCAGCTGGAGGATCTGCAGCGCCTCACGCCAGGGGAGAAGGGCATCCAGCTGGATGTTAGC
CGTACTCCGGAACAGCTGCTCGACGATGCGCTGAACGCCGCGATGTTCGCGAAGAAGGCATACGCGCGCTAG

Upstream 100 bases:

>100_bases
GTTCCGGTTCGAACCGGAACCCCGCTTTTGGCGTCAATAATAAAAATAAAACGGCATACTGGAAGGCAGTAACGGGCACC
GCGAAGAAGAAAGGAGCCAC

Downstream 100 bases:

>100_bases
CAGGCCAGCGCTAGTAATCGAAGTTCGTGTCGTAGCGGTACCGCAGCTCGTCGAATTGCTCGCGGAAGCGCTTCTGCAGC
TCCTCGTCTTCCTGCTTTCG

Product: putative gluconokinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSSQETPATLHVVVMGVSGSGKTTLARAFAEKTGWQLQEADDLHPEGALEILQDGKLPPEEGRRTWLRIVRDWIADEAAQ
GNNTVTACTALRIDHREILNDAGENATVFYVHLYGTEDVLAERMKNRVGDADMPRELLTAQLEDLQRLTPGEKGIQLDVS
RTPEQLLDDALNAAMFAKKAYAR

Sequences:

>Translated_183_residues
MSSQETPATLHVVVMGVSGSGKTTLARAFAEKTGWQLQEADDLHPEGALEILQDGKLPPEEGRRTWLRIVRDWIADEAAQ
GNNTVTACTALRIDHREILNDAGENATVFYVHLYGTEDVLAERMKNRVGDADMPRELLTAQLEDLQRLTPGEKGIQLDVS
RTPEQLLDDALNAAMFAKKAYAR
>Mature_182_residues
SSQETPATLHVVVMGVSGSGKTTLARAFAEKTGWQLQEADDLHPEGALEILQDGKLPPEEGRRTWLRIVRDWIADEAAQG
NNTVTACTALRIDHREILNDAGENATVFYVHLYGTEDVLAERMKNRVGDADMPRELLTAQLEDLQRLTPGEKGIQLDVSR
TPEQLLDDALNAAMFAKKAYAR

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=172, Percent_Identity=32.5581395348837, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI87082265, Length=141, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=6e-14,
Organism=Escherichia coli, GI1790719, Length=150, Percent_Identity=29.3333333333333, Blast_Score=66, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25146487, Length=147, Percent_Identity=29.9319727891156, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 20240; Mature: 20109

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQETPATLHVVVMGVSGSGKTTLARAFAEKTGWQLQEADDLHPEGALEILQDGKLPPE
CCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHH
EGRRTWLRIVRDWIADEAAQGNNTVTACTALRIDHREILNDAGENATVFYVHLYGTEDVL
HHHHHHHHHHHHHHHHHHCCCCCCEEEHHEEHHHHHHHHHCCCCCCEEEEEEEECCHHHH
AERMKNRVGDADMPRELLTAQLEDLQRLTPGEKGIQLDVSRTPEQLLDDALNAAMFAKKA
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
YAR
HCC
>Mature Secondary Structure 
SSQETPATLHVVVMGVSGSGKTTLARAFAEKTGWQLQEADDLHPEGALEILQDGKLPPE
CCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHH
EGRRTWLRIVRDWIADEAAQGNNTVTACTALRIDHREILNDAGENATVFYVHLYGTEDVL
HHHHHHHHHHHHHHHHHHCCCCCCEEEHHEEHHHHHHHHHCCCCCCEEEEEEEECCHHHH
AERMKNRVGDADMPRELLTAQLEDLQRLTPGEKGIQLDVSRTPEQLLDDALNAAMFAKKA
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
YAR
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]