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The map label for this gene is clpC [H]

Identifier: 68535364

GI number: 68535364

Start: 365369

End: 368026

Strand: Direct

Name: clpC [H]

Synonym: jk0299

Alternate gene names: 68535364

Gene position: 365369-368026 (Clockwise)

Preceding gene: 68535361

Following gene: 68535368

Centisome position: 14.84

GC content: 64.9

Gene sequence:

>2658_bases
ATGTTCGAGAGGTTCACGGATCGCGCGCGCCGCGTCGTTGTGTTGGCGCAGGAGGAAGCACGCGCGCTGAATCACAACTA
CATCGGCACCGAGCACATCCTGCTCGGCCTGATCCAAGAGGGCGAAGGTGTCGCGGCGAAGGCCCTGGAGTCCATGGGCA
TCTCCCTGGATGCCGTGCGCACCGAGGTCAAGGACATCATCGGCACCGGTGGCCACCCGCCGAGCGGCTACATCCCGTTC
ACCCCGCGCGCCAAGAAGGTGCTGGAACTCGCGCTGCGCGAGGCACTGCAGCTGGGCCACAAGTACATCGGCACCGAGCA
CATCCTGCTGGGCCTCATCCGCGAGGGTGAAGGCGTGGCGGCGCAGGTGCTGGTCAAGCTGGGTGCGGACCTGTCCCGCG
TGCGCCAGCAGGTAATTCAGCTGCTCAGCGGCTACGAGGGGAACGATGAAGAAAGCGGTGGCGGCGAGCCCGCTACCGCC
GGTGTGGGCAGCAGCCCGGAGGGTGCACCGAGCCGCCCGGGCCAGAAGTCCAACTCCCTGGTACTGGACCAGTTTGGCCG
TAACCTCACCCAGGCAGCGAAGGATGGCAAGCTGGATCCTGTCGTGGGTCGCGAGAACGAGATCGAGCGCGTAATGCAGG
TGCTGTCCCGCCGCACCAAGAACAACCCGGTACTGATCGGCGAGCCCGGTGTGGGTAAGACCGCCGTGGTCGAGGGGCTG
GCGCTGGACATCGTCAACGGCAAGGTGCCGGAGACTCTGAAGGATAAGCAGCTGTACTCCCTGGATCTGGGCTCCCTGGT
GGCGGGTTCCCGCTACCGCGGTGACTTCGAGGAGCGTCTGAAGAAGGTGCTGAAGGAGATCAACCAGCGCGGTGACATCA
TTCTGTTTATCGACGAGATCCACACCCTCGTCGGCGCAGGTGCCGCCGAGGGCGCGATCGACGCTGCCAGCATCCTGAAG
CCGAAGCTGGCTCGCGGCGAGCTGCAGACCATCGGTGCCACCACCCTGGACGAGTACCGCAAGCACATCGAGAAGGACGC
CGCGCTGGAGCGCCGCTTCCAGCCTGTACAGGTTCCGGAGCCTTCCGTGGAGCTGACCGTGGAGATCCTTAAGGGGCTGC
GCGACCGCTACGAGGCGCACCACCGCGTATCCATCACTGATGGTGCGCTGAAGGCCGCAGCCCAGCTGGCAGATCGCTAC
ATCAACGACCGCTTCCTGCCGGATAAGGCCGTGGACCTGATCGACGAGGCCGGCGCCCGCATGCGCATCAAGCGCATGAC
CGCCCCGAAGGCCATCCAGGACATCGACGACAAGATCGCCGAGGTGCGCCGTAAGAAGGAGGCTGCCATCGACGACCAGG
ACTTCGAGAAGGCAGCAGCTCTGCGTGACGACGAGCGCAAGCTGGGCGAAGAGCGCGCGGAGAAGGAAAAGGCCTGGCGC
GCCGGCGAGCTGGACGAGGTCGCCGAGGTGGGCGAGGAGCAGATCGCCGAGGTCATGGGCACCTGGACCGGCATCCCCGT
GTTCAAGCTCACCGAGGAAGAATCCACCCGCCTGCTGCACATGGAAGACGAGCTGCACAAGCGCATCATCGGCCAGGACG
ATGCCGTCAAGGCCGTCTCCCGTGCCATCCGCCGCACCCGCGCCGGCCTGAAGGACCCGAAGCGCCCGTCCGGTTCGTTC
ATCTTCGCCGGCCCGTCCGGTGTGGGTAAGACTGAGCTGTCGAAGGCGCTGGCCGAGTTCCTGTTCGGCGACGATGACGC
GCTGATCCAGATCGACATGGGCGAGTTCCACGACAAGTTCACGGCATCCCGCCTGTTCGGTGCGCCTCCGGGATACGTCG
GCTACGACGAGGGTGGGCAGCTGACCGAGAAGGTCCGCCGCAAGCCGTTCTCTGTGGTGCTGTTCGACGAGATCGAGAAG
GCCCACACGGAGATCTACAACACCCTGCTGCAGGTGCTGGAAGACGGTCGCCTGACCGACGGCCAGGGCCGCATGGTGGA
CTTCAAGAACACCGTTCTGATCTTCACCTCCAACCTGGGCACCAGGGACATCTCCAAGGCTGTGGGCATGGGCTTCAGCG
CTTCTGGTGAGGCCGACGAGGACACCCAGTACGAGCGGATGAAGCAGAAGGTCGACGACGAGCTGAAGAAGCACTTCCGC
CCGGAGTTCCTGAACCGCATCGACGACATCGTGGTCTTCCACCAGCTAACTCGCGAGCAGATCGTGCAGATGGTGGACCT
GCTGCTGGGGCGCGTGCGCACCGCGCTGGAGGCAAAGGACATGGGTCTGGAGCTCACCGAGCAGGCGAAGTCCCTGCTGG
CCAAGCGTGGTTTCGACCCGGTACTGGGTGCCCGCCCGCTGCGCCGCACGATCCAGCGCGAGATCGAGGATCACCTGTCC
GAGAAGATCCTGTTCGGCGAGATCGGCGCCGGCGAGATCGTCACCGTCGACGTCGAAAACTGGGACGGCGAGTCCAAGGG
CGACGATGCGAAGTTCGTCTTCGACACCAAGCCCAAGCCGCTGCCGGAGGTCGGCGAGGATGACCTCTCCGCCGACGAGG
CCCAGGAGGCGGTGTCTGTCGCCGCCGAGGGCAACGTGCCGGAGGATAAGGACTTTGACGCCGCAGATTCCAGCGACGAC
TGGAATCAGAAAGGCTAA

Upstream 100 bases:

>100_bases
AGTGTTGTGTGAAAGGCGATATGAGTTGTCCACACTCACGGCTAAGGTGGGCAACATTGGCGAATACGCAAGCTACATCT
TTTGATAAAGGGAGCACACC

Downstream 100 bases:

>100_bases
CTAAGCCTTTTGGGCTGGACCTTGTTGATTAGGCCTTGTTGAACTGCACTGGGCGATCGTGGATCACGTTATCCACCCAG
TCCAGCGCAGGCAGCAGGTG

Product: ATP-dependent Clp protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 885; Mature: 885

Protein sequence:

>885_residues
MFERFTDRARRVVVLAQEEARALNHNYIGTEHILLGLIQEGEGVAAKALESMGISLDAVRTEVKDIIGTGGHPPSGYIPF
TPRAKKVLELALREALQLGHKYIGTEHILLGLIREGEGVAAQVLVKLGADLSRVRQQVIQLLSGYEGNDEESGGGEPATA
GVGSSPEGAPSRPGQKSNSLVLDQFGRNLTQAAKDGKLDPVVGRENEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGL
ALDIVNGKVPETLKDKQLYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEIHTLVGAGAAEGAIDAASILK
PKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPEPSVELTVEILKGLRDRYEAHHRVSITDGALKAAAQLADRY
INDRFLPDKAVDLIDEAGARMRIKRMTAPKAIQDIDDKIAEVRRKKEAAIDDQDFEKAAALRDDERKLGEERAEKEKAWR
AGELDEVAEVGEEQIAEVMGTWTGIPVFKLTEEESTRLLHMEDELHKRIIGQDDAVKAVSRAIRRTRAGLKDPKRPSGSF
IFAGPSGVGKTELSKALAEFLFGDDDALIQIDMGEFHDKFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVVLFDEIEK
AHTEIYNTLLQVLEDGRLTDGQGRMVDFKNTVLIFTSNLGTRDISKAVGMGFSASGEADEDTQYERMKQKVDDELKKHFR
PEFLNRIDDIVVFHQLTREQIVQMVDLLLGRVRTALEAKDMGLELTEQAKSLLAKRGFDPVLGARPLRRTIQREIEDHLS
EKILFGEIGAGEIVTVDVENWDGESKGDDAKFVFDTKPKPLPEVGEDDLSADEAQEAVSVAAEGNVPEDKDFDAADSSDD
WNQKG

Sequences:

>Translated_885_residues
MFERFTDRARRVVVLAQEEARALNHNYIGTEHILLGLIQEGEGVAAKALESMGISLDAVRTEVKDIIGTGGHPPSGYIPF
TPRAKKVLELALREALQLGHKYIGTEHILLGLIREGEGVAAQVLVKLGADLSRVRQQVIQLLSGYEGNDEESGGGEPATA
GVGSSPEGAPSRPGQKSNSLVLDQFGRNLTQAAKDGKLDPVVGRENEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGL
ALDIVNGKVPETLKDKQLYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEIHTLVGAGAAEGAIDAASILK
PKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPEPSVELTVEILKGLRDRYEAHHRVSITDGALKAAAQLADRY
INDRFLPDKAVDLIDEAGARMRIKRMTAPKAIQDIDDKIAEVRRKKEAAIDDQDFEKAAALRDDERKLGEERAEKEKAWR
AGELDEVAEVGEEQIAEVMGTWTGIPVFKLTEEESTRLLHMEDELHKRIIGQDDAVKAVSRAIRRTRAGLKDPKRPSGSF
IFAGPSGVGKTELSKALAEFLFGDDDALIQIDMGEFHDKFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVVLFDEIEK
AHTEIYNTLLQVLEDGRLTDGQGRMVDFKNTVLIFTSNLGTRDISKAVGMGFSASGEADEDTQYERMKQKVDDELKKHFR
PEFLNRIDDIVVFHQLTREQIVQMVDLLLGRVRTALEAKDMGLELTEQAKSLLAKRGFDPVLGARPLRRTIQREIEDHLS
EKILFGEIGAGEIVTVDVENWDGESKGDDAKFVFDTKPKPLPEVGEDDLSADEAQEAVSVAAEGNVPEDKDFDAADSSDD
WNQKG
>Mature_885_residues
MFERFTDRARRVVVLAQEEARALNHNYIGTEHILLGLIQEGEGVAAKALESMGISLDAVRTEVKDIIGTGGHPPSGYIPF
TPRAKKVLELALREALQLGHKYIGTEHILLGLIREGEGVAAQVLVKLGADLSRVRQQVIQLLSGYEGNDEESGGGEPATA
GVGSSPEGAPSRPGQKSNSLVLDQFGRNLTQAAKDGKLDPVVGRENEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGL
ALDIVNGKVPETLKDKQLYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEIHTLVGAGAAEGAIDAASILK
PKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPEPSVELTVEILKGLRDRYEAHHRVSITDGALKAAAQLADRY
INDRFLPDKAVDLIDEAGARMRIKRMTAPKAIQDIDDKIAEVRRKKEAAIDDQDFEKAAALRDDERKLGEERAEKEKAWR
AGELDEVAEVGEEQIAEVMGTWTGIPVFKLTEEESTRLLHMEDELHKRIIGQDDAVKAVSRAIRRTRAGLKDPKRPSGSF
IFAGPSGVGKTELSKALAEFLFGDDDALIQIDMGEFHDKFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVVLFDEIEK
AHTEIYNTLLQVLEDGRLTDGQGRMVDFKNTVLIFTSNLGTRDISKAVGMGFSASGEADEDTQYERMKQKVDDELKKHFR
PEFLNRIDDIVVFHQLTREQIVQMVDLLLGRVRTALEAKDMGLELTEQAKSLLAKRGFDPVLGARPLRRTIQREIEDHLS
EKILFGEIGAGEIVTVDVENWDGESKGDDAKFVFDTKPKPLPEVGEDDLSADEAQEAVSVAAEGNVPEDKDFDAADSSDD
WNQKG

Specific function: Part Of A Stress-Induced Multi-Chaperone System, It Is Involved In The Recovery Of The Cell From Heat-Induced Damage, In Cooperation With Dnak, Dnaj And Grpe. Acts Before Dnak, In The Processing Of Protein Aggregates. Protein Binding Stimulates The Atpase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=321, Percent_Identity=33.9563862928349, Blast_Score=182, Evalue=2e-45,
Organism=Escherichia coli, GI1788943, Length=888, Percent_Identity=44.481981981982, Blast_Score=710, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=817, Percent_Identity=39.0452876376989, Blast_Score=543, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6320464, Length=711, Percent_Identity=46.8354430379747, Blast_Score=619, Evalue=1e-178,
Organism=Saccharomyces cerevisiae, GI6323002, Length=939, Percent_Identity=37.912673056443, Blast_Score=556, Evalue=1e-159,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 97586; Mature: 97586

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTDRARRVVVLAQEEARALNHNYIGTEHILLGLIQEGEGVAAKALESMGISLDAVR
CCCHHHHHCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHH
TEVKDIIGTGGHPPSGYIPFTPRAKKVLELALREALQLGHKYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHH
AQVLVKLGADLSRVRQQVIQLLSGYEGNDEESGGGEPATAGVGSSPEGAPSRPGQKSNSL
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VLDQFGRNLTQAAKDGKLDPVVGRENEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGL
HHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHH
ALDIVNGKVPETLKDKQLYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEI
HHEECCCCCCCHHCCCHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHH
HTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPE
HHHHCCCCCCCCHHHHHHHCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
PSVELTVEILKGLRDRYEAHHRVSITDGALKAAAQLADRYINDRFLPDKAVDLIDEAGAR
CCHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
MRIKRMTAPKAIQDIDDKIAEVRRKKEAAIDDQDFEKAAALRDDERKLGEERAEKEKAWR
EEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHC
AGELDEVAEVGEEQIAEVMGTWTGIPVFKLTEEESTRLLHMEDELHKRIIGQDDAVKAVS
CCCHHHHHHHCHHHHHHHHHHCCCCCEEEECCCCCCEEEEHHHHHHHHHCCCCHHHHHHH
RAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALAEFLFGDDDALIQIDMGEFHDKF
HHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHH
TASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVVLFDEIEKAHTEIYNTLLQVLEDGRLTD
HHHHHCCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
GQGRMVDFKNTVLIFTSNLGTRDISKAVGMGFSASGEADEDTQYERMKQKVDDELKKHFR
CCCCEEEECCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
PEFLNRIDDIVVFHQLTREQIVQMVDLLLGRVRTALEAKDMGLELTEQAKSLLAKRGFDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
VLGARPLRRTIQREIEDHLSEKILFGEIGAGEIVTVDVENWDGESKGDDAKFVFDTKPKP
CCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCCCC
LPEVGEDDLSADEAQEAVSVAAEGNVPEDKDFDAADSSDDWNQKG
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFERFTDRARRVVVLAQEEARALNHNYIGTEHILLGLIQEGEGVAAKALESMGISLDAVR
CCCHHHHHCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHH
TEVKDIIGTGGHPPSGYIPFTPRAKKVLELALREALQLGHKYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHH
AQVLVKLGADLSRVRQQVIQLLSGYEGNDEESGGGEPATAGVGSSPEGAPSRPGQKSNSL
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VLDQFGRNLTQAAKDGKLDPVVGRENEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGL
HHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHH
ALDIVNGKVPETLKDKQLYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEI
HHEECCCCCCCHHCCCHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHH
HTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPE
HHHHCCCCCCCCHHHHHHHCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
PSVELTVEILKGLRDRYEAHHRVSITDGALKAAAQLADRYINDRFLPDKAVDLIDEAGAR
CCHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
MRIKRMTAPKAIQDIDDKIAEVRRKKEAAIDDQDFEKAAALRDDERKLGEERAEKEKAWR
EEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHC
AGELDEVAEVGEEQIAEVMGTWTGIPVFKLTEEESTRLLHMEDELHKRIIGQDDAVKAVS
CCCHHHHHHHCHHHHHHHHHHCCCCCEEEECCCCCCEEEEHHHHHHHHHCCCCHHHHHHH
RAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALAEFLFGDDDALIQIDMGEFHDKF
HHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHH
TASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVVLFDEIEKAHTEIYNTLLQVLEDGRLTD
HHHHHCCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
GQGRMVDFKNTVLIFTSNLGTRDISKAVGMGFSASGEADEDTQYERMKQKVDDELKKHFR
CCCCEEEECCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
PEFLNRIDDIVVFHQLTREQIVQMVDLLLGRVRTALEAKDMGLELTEQAKSLLAKRGFDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
VLGARPLRRTIQREIEDHLSEKILFGEIGAGEIVTVDVENWDGESKGDDAKFVFDTKPKP
CCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCCCC
LPEVGEDDLSADEAQEAVSVAAEGNVPEDKDFDAADSSDDWNQKG
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]