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The map label for this gene is ack

Identifier: 68535316

GI number: 68535316

Start: 308991

End: 310202

Strand: Direct

Name: ack

Synonym: jk0251

Alternate gene names: 68535316

Gene position: 308991-310202 (Clockwise)

Preceding gene: 68535315

Following gene: 68535320

Centisome position: 12.55

GC content: 61.3

Gene sequence:

>1212_bases
GTGACCAAGTACGTACTCGTCCTCAACTCGGGCTCCAGCTCCATCAAGTTCCAAGTCCTCGACCCGGAAGCAAACGCGAC
GGCGGACCCATTCGTCTCCGGCATCGTCGAGAAAATCGGCGAAAAGAAGGGGCACATCCAGATTCAGACGGAAACGTCGA
AGATGGAAGACAATCGCCCTATCCTCAGCCACTCTGTTGGCCTAGAACGCGCCTTCGGCATGATGACGCTACTGGGCGTC
GGCCCCCAAGACCTAGACCTGGTAGCAGCAGGGCACCGCGTGGTCCACGGTGGCGCGACGTTCACAGAGCCTGTGCTCAT
CGACGATGAGGTGATCGAGCAGCTCAAGGAGCTCATCCCGCTGGCGCCGCTACACAACCCCGCCAACATCGACGGCATCG
AAAATGCCCGCGCGCTGCTGGAGCACGTGCCGCACGTGGCCGTGTTCGACACCGCGTTCTTCTCCACACTGCCGGAGCAC
GCGGCGAACTACGCCATCAAGAAGGACATCGCCGACGAGTACAACATCCGCCGCTACGGCTTCCACGGCACCAGCCACGA
GTACGTGTCCTCCAAGGTTCCGGACCTGCTGGGCAAGCCCGCCGAGGAGGTCAACCAGATCACCCTGCACCTGGGCAACG
GTGCCTCGGCCGCCGCGATTCGTGGCGGTGAGGCAGTAGATACGACGATGGGATTGACGCCACTTGCCGGCCTGGTGATG
GGCACCCGTTCCGGCGACATTGACCCAGGCATTATTTTCCACCTGGCGCGCTCCGGCGGGATGACGGTGGATCAGGCAGA
TAAGCTGCTAAACCGCGAGTCCGGTCTGAAGGGTATGGCTGGCGTGAACGATTTCCGCGAGCTGAAAACCTTGATCGAGG
ACGGCGATGAAAATGCTCAGCTGGCCTACGACGTGTACATCCACGCGCTGCGTCGCTTTATTGGGTCTTACATGCTGATC
CTCGGTGGCGTGGATGCGATTGTGTTCACCGCGGGCGTGGGCGAGAACGCGGTGCAGGTGCGCCGCGATGCGATGGCTGA
CCTGCAGAACTTTGGTATTGAGATTGACGATGCGCGGAATGAGAACTCCGAGGGGATTGTCGGCGCGCGGGAGATCTCTA
CTGACGATTCGACGGTGAAGGTGTTCGTGGTTCCGACGAATGAGGAGCTGGCAATCGCGCGCCAGGCGACGGAGCTGGCC
GAGCAGCAGTAG

Upstream 100 bases:

>100_bases
CATTTGCCAGCGGGAACTACCCCGCCCGCTGGCTGAGCGGCAAAACGGCGCCGGCAGAAGAAGAGAAAAAGAGAATAAGA
GAAAAGAAGAGAGAAGAATA

Downstream 100 bases:

>100_bases
GGTCTGGAGCTGGCGATTGCGCGCTAGGCGACGGAGCCGGCCGAGCAGCAGTAGGGGCTGCCTGGGGCGGCAGTAGGGTC
TGCCCGGGGCGCCGGGTTGC

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTKYVLVLNSGSSSIKFQVLDPEANATADPFVSGIVEKIGEKKGHIQIQTETSKMEDNRPILSHSVGLERAFGMMTLLGV
GPQDLDLVAAGHRVVHGGATFTEPVLIDDEVIEQLKELIPLAPLHNPANIDGIENARALLEHVPHVAVFDTAFFSTLPEH
AANYAIKKDIADEYNIRRYGFHGTSHEYVSSKVPDLLGKPAEEVNQITLHLGNGASAAAIRGGEAVDTTMGLTPLAGLVM
GTRSGDIDPGIIFHLARSGGMTVDQADKLLNRESGLKGMAGVNDFRELKTLIEDGDENAQLAYDVYIHALRRFIGSYMLI
LGGVDAIVFTAGVGENAVQVRRDAMADLQNFGIEIDDARNENSEGIVGAREISTDDSTVKVFVVPTNEELAIARQATELA
EQQ

Sequences:

>Translated_403_residues
MTKYVLVLNSGSSSIKFQVLDPEANATADPFVSGIVEKIGEKKGHIQIQTETSKMEDNRPILSHSVGLERAFGMMTLLGV
GPQDLDLVAAGHRVVHGGATFTEPVLIDDEVIEQLKELIPLAPLHNPANIDGIENARALLEHVPHVAVFDTAFFSTLPEH
AANYAIKKDIADEYNIRRYGFHGTSHEYVSSKVPDLLGKPAEEVNQITLHLGNGASAAAIRGGEAVDTTMGLTPLAGLVM
GTRSGDIDPGIIFHLARSGGMTVDQADKLLNRESGLKGMAGVNDFRELKTLIEDGDENAQLAYDVYIHALRRFIGSYMLI
LGGVDAIVFTAGVGENAVQVRRDAMADLQNFGIEIDDARNENSEGIVGAREISTDDSTVKVFVVPTNEELAIARQATELA
EQQ
>Mature_402_residues
TKYVLVLNSGSSSIKFQVLDPEANATADPFVSGIVEKIGEKKGHIQIQTETSKMEDNRPILSHSVGLERAFGMMTLLGVG
PQDLDLVAAGHRVVHGGATFTEPVLIDDEVIEQLKELIPLAPLHNPANIDGIENARALLEHVPHVAVFDTAFFSTLPEHA
ANYAIKKDIADEYNIRRYGFHGTSHEYVSSKVPDLLGKPAEEVNQITLHLGNGASAAAIRGGEAVDTTMGLTPLAGLVMG
TRSGDIDPGIIFHLARSGGMTVDQADKLLNRESGLKGMAGVNDFRELKTLIEDGDENAQLAYDVYIHALRRFIGSYMLIL
GGVDAIVFTAGVGENAVQVRRDAMADLQNFGIEIDDARNENSEGIVGAREISTDDSTVKVFVVPTNEELAIARQATELAE
QQ

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI1788633, Length=410, Percent_Identity=45.3658536585366, Blast_Score=316, Evalue=1e-87,
Organism=Escherichia coli, GI145693184, Length=399, Percent_Identity=40.8521303258145, Blast_Score=283, Evalue=2e-77,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ACKA_CORJK (Q4JXQ4)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250021.1
- ProteinModelPortal:   Q4JXQ4
- SMR:   Q4JXQ4
- STRING:   Q4JXQ4
- GeneID:   3432028
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0251
- NMPDR:   fig|306537.3.peg.795
- eggNOG:   COG0282
- HOGENOM:   HBG285863
- OMA:   EELMIAC
- ProtClustDB:   PRK00180
- BioCyc:   CJEI306537:JK0251-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 43403; Mature: 43271

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYVLVLNSGSSSIKFQVLDPEANATADPFVSGIVEKIGEKKGHIQIQTETSKMEDNRP
CCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
ILSHSVGLERAFGMMTLLGVGPQDLDLVAAGHRVVHGGATFTEPVLIDDEVIEQLKELIP
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECCCCCCCCEEECHHHHHHHHHHCC
LAPLHNPANIDGIENARALLEHVPHVAVFDTAFFSTLPEHAANYAIKKDIADEYNIRRYG
CCCCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
FHGTSHEYVSSKVPDLLGKPAEEVNQITLHLGNGASAAAIRGGEAVDTTMGLTPLAGLVM
CCCCCHHHHHHCCHHHHCCCHHHHCEEEEEECCCCCEEEECCCCCHHHHCCHHHHHHHHE
GTRSGDIDPGIIFHLARSGGMTVDQADKLLNRESGLKGMAGVNDFRELKTLIEDGDENAQ
ECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCE
LAYDVYIHALRRFIGSYMLILGGVDAIVFTAGVGENAVQVRRDAMADLQNFGIEIDDARN
EHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEECCCC
ENSEGIVGAREISTDDSTVKVFVVPTNEELAIARQATELAEQQ
CCCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKYVLVLNSGSSSIKFQVLDPEANATADPFVSGIVEKIGEKKGHIQIQTETSKMEDNRP
CEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
ILSHSVGLERAFGMMTLLGVGPQDLDLVAAGHRVVHGGATFTEPVLIDDEVIEQLKELIP
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECCCCCCCCEEECHHHHHHHHHHCC
LAPLHNPANIDGIENARALLEHVPHVAVFDTAFFSTLPEHAANYAIKKDIADEYNIRRYG
CCCCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
FHGTSHEYVSSKVPDLLGKPAEEVNQITLHLGNGASAAAIRGGEAVDTTMGLTPLAGLVM
CCCCCHHHHHHCCHHHHCCCHHHHCEEEEEECCCCCEEEECCCCCHHHHCCHHHHHHHHE
GTRSGDIDPGIIFHLARSGGMTVDQADKLLNRESGLKGMAGVNDFRELKTLIEDGDENAQ
ECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCE
LAYDVYIHALRRFIGSYMLILGGVDAIVFTAGVGENAVQVRRDAMADLQNFGIEIDDARN
EHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEECCCC
ENSEGIVGAREISTDDSTVKVFVVPTNEELAIARQATELAEQQ
CCCCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA