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The map label for this gene is yybE [H]

Identifier: 68535209

GI number: 68535209

Start: 173718

End: 174626

Strand: Direct

Name: yybE [H]

Synonym: jk0144

Alternate gene names: 68535209

Gene position: 173718-174626 (Clockwise)

Preceding gene: 68535204

Following gene: 68535215

Centisome position: 7.05

GC content: 67.44

Gene sequence:

>909_bases
GTGAAAGACCTAACGTGGCTCCTGGACTTGGCTGAAACCCAGAACATGGTGGATACGTCGCTGCGCCTGGGGATCAGCCA
GTCGGCGCTTTCGCGGAGGCTATCGGCGCTGGAAAGAGAGCTCGGTGCGGAGCTGTTCGACCGCAACGGCAGGCACCTCG
CCCTCAACGAATGCGGAGCCGCGCTCGCCACGAACGCCCGCGAGGCTAACGAGGCATGGCAGCGGGGAGTCGACGAAGTA
CACCGGCTGATGGACCCGGAGCGGGGTACCGTGCGCGTGGACTTCATGCACTCACTGGGAACGTGGATGGTGCCGCAGCT
GTTGCGGGAGTTTAGGAACGCGCACCCGCAGGTGAGGTTCGAGCTGGTGCAGGGGGCCGCGCAACCGCTAACGGACCGCG
TGATCGCCGGAGAATCCGATGTGGCGATGGTGGGGCCGAAGCCCCATGCGCTGGTGGAGGCTGGTGAAGTGCGCTGGCAG
CAGCTAGCCACCCAGAGGCTGGCGATGGCGGTTCCGACGAACCACCGCTGGGCTGAACGCACAAGCATCAGCATCACAGA
GGCCGCGGACGAGCCCTTCGTGGCCATGCTGCCGGGGTACGGAACCCGTATGCTGTTGGACGATCTGGCGGCCGCGGCGG
GCTTCCGGCCACGCCTGGTGTTTGAGTCGATGGAGCTAACCACGATGGCGGGGCTGGTAAGCGCCGGTTTGGGCGTGGCC
CTGCTGCCGATGGGGGACCCGAACCTGGTGGTCGCGGGCATAGAAATGCTCCCCCTCGAGGAAGACCGCGAGAGGGAGCT
GGGAATGGTCTGGAGCGCACGGGCCCGGTCGGCGCCCGCCGCCGAGGCGTTCCGCGCGTTCGTCGTGGACCAGGCGGTCC
GGCGCGACGGTCGGCTGCGCTTCGGCTAG

Upstream 100 bases:

>100_bases
TATCAATTCACTAAATGCAATAAATAGCTTTAGCTGTCCCGGAAGGCGCATATGCTGAAGTGTGGGCGTCGATAAGAAGG
CAAGAAGGAAGATACAGAGC

Downstream 100 bases:

>100_bases
GCGCTGATCCTTAAGCGCCGATGGTGCCGAAGTCGTCCTTCCAGGCAACCACGGTGGCCGGGCGGGCGATGGAATCGCCG
CCATCCGGCCAGTGGGAGGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKDLTWLLDLAETQNMVDTSLRLGISQSALSRRLSALERELGAELFDRNGRHLALNECGAALATNAREANEAWQRGVDEV
HRLMDPERGTVRVDFMHSLGTWMVPQLLREFRNAHPQVRFELVQGAAQPLTDRVIAGESDVAMVGPKPHALVEAGEVRWQ
QLATQRLAMAVPTNHRWAERTSISITEAADEPFVAMLPGYGTRMLLDDLAAAAGFRPRLVFESMELTTMAGLVSAGLGVA
LLPMGDPNLVVAGIEMLPLEEDRERELGMVWSARARSAPAAEAFRAFVVDQAVRRDGRLRFG

Sequences:

>Translated_302_residues
MKDLTWLLDLAETQNMVDTSLRLGISQSALSRRLSALERELGAELFDRNGRHLALNECGAALATNAREANEAWQRGVDEV
HRLMDPERGTVRVDFMHSLGTWMVPQLLREFRNAHPQVRFELVQGAAQPLTDRVIAGESDVAMVGPKPHALVEAGEVRWQ
QLATQRLAMAVPTNHRWAERTSISITEAADEPFVAMLPGYGTRMLLDDLAAAAGFRPRLVFESMELTTMAGLVSAGLGVA
LLPMGDPNLVVAGIEMLPLEEDRERELGMVWSARARSAPAAEAFRAFVVDQAVRRDGRLRFG
>Mature_302_residues
MKDLTWLLDLAETQNMVDTSLRLGISQSALSRRLSALERELGAELFDRNGRHLALNECGAALATNAREANEAWQRGVDEV
HRLMDPERGTVRVDFMHSLGTWMVPQLLREFRNAHPQVRFELVQGAAQPLTDRVIAGESDVAMVGPKPHALVEAGEVRWQ
QLATQRLAMAVPTNHRWAERTSISITEAADEPFVAMLPGYGTRMLLDDLAAAAGFRPRLVFESMELTTMAGLVSAGLGVA
LLPMGDPNLVVAGIEMLPLEEDRERELGMVWSARARSAPAAEAFRAFVVDQAVRRDGRLRFG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=294, Percent_Identity=28.2312925170068, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI145693105, Length=283, Percent_Identity=24.3816254416961, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787530, Length=265, Percent_Identity=26.7924528301887, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI157672245, Length=242, Percent_Identity=25.6198347107438, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=29.2181069958848, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788481, Length=242, Percent_Identity=25.6198347107438, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790208, Length=298, Percent_Identity=27.1812080536913, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788748, Length=297, Percent_Identity=24.2424242424242, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788887, Length=291, Percent_Identity=23.3676975945017, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI2367136, Length=283, Percent_Identity=24.3816254416961, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33345; Mature: 33345

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLTWLLDLAETQNMVDTSLRLGISQSALSRRLSALERELGAELFDRNGRHLALNECGA
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCH
ALATNAREANEAWQRGVDEVHRLMDPERGTVRVDFMHSLGTWMVPQLLREFRNAHPQVRF
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCHHHHHHHHHHHHCCCCCEEH
ELVQGAAQPLTDRVIAGESDVAMVGPKPHALVEAGEVRWQQLATQRLAMAVPTNHRWAER
HHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHC
TSISITEAADEPFVAMLPGYGTRMLLDDLAAAAGFRPRLVFESMELTTMAGLVSAGLGVA
CCEEEECCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEE
LLPMGDPNLVVAGIEMLPLEEDRERELGMVWSARARSAPAAEAFRAFVVDQAVRRDGRLR
EEECCCCCEEEEEEEEECCCCCHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHCCCCC
FG
CC
>Mature Secondary Structure
MKDLTWLLDLAETQNMVDTSLRLGISQSALSRRLSALERELGAELFDRNGRHLALNECGA
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCH
ALATNAREANEAWQRGVDEVHRLMDPERGTVRVDFMHSLGTWMVPQLLREFRNAHPQVRF
HHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCHHHHHHHHHHHHCCCCCEEH
ELVQGAAQPLTDRVIAGESDVAMVGPKPHALVEAGEVRWQQLATQRLAMAVPTNHRWAER
HHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHC
TSISITEAADEPFVAMLPGYGTRMLLDDLAAAAGFRPRLVFESMELTTMAGLVSAGLGVA
CCEEEECCCCCCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEE
LLPMGDPNLVVAGIEMLPLEEDRERELGMVWSARARSAPAAEAFRAFVVDQAVRRDGRLR
EEECCCCCEEEEEEEEECCCCCHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHCCCCC
FG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]