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The map label for this gene is potH [H]

Identifier: 77761166

GI number: 77761166

Start: 2162356

End: 2163267

Strand: Direct

Name: potH [H]

Synonym: XC_1777

Alternate gene names: 77761166

Gene position: 2162356-2163267 (Clockwise)

Preceding gene: 66768097

Following gene: 66768099

Centisome position: 42.0

GC content: 62.83

Gene sequence:

>912_bases
TTGCTAACCACTCTTAGTCGCGGCCTGCCGGGTGCGCGTTGGGGCGTGATCGCCGCACCGTATCTGTGGTTGCTGGTGTT
CTTCGCGATCCCGTTCCTGATCGTGCTGAAGATTTCGTTTGCCGAACGCGCAACCGCGATGCCGCCGTACACGCCGCTGT
TTGCGTATGCGGCCGATGGCGCGGTGAGCCTCAAACTGCATCTGGGCAACTACCTGGCCCTGCTGCGCGACAGCCAGTAC
GTGGCCGCTTACCTGAGTTCGATCAAGATCGCTGCGATTTCCACCGCACTGGCGCTATTGATCGGCTACCCGATGGCATA
CGTGATCGCGCGCCTGCCTCTGGCCACCCGCAACGTGGCGATGATGCTGGTGGTGTTGCCGTCTTGGACCTCGTTCCTGA
TCCGTGTATACGCATGGATCGGCATTCTCGATGGCAACGGCCTGCTCAATCAGGCTCTGCTGGCGCTGGGTGTGATCGAG
CAGCCGCTGCAGTTGCTGTACACGCCGATCGCCGCCTACATCGGCTTCGTCTATTGCTATCTGCCCTTCATGGTGCTGCC
GCTGTACGCCAACCTGGTCAAGCACGATTCGCGGCTGCTGGAGGTGGCTTACGACCTGGGGGCGCGGCCGTGGCAGGCAT
TCGTGCGCATCACCTTGCCGCTGTCGCGCAACGGCATCGTCGCCGGCTGCATGCTGGTGATGATTCCGGCGGTGGGCGAG
TTCGTGATTCCCGAGATGCTGGGCGGTCCCGGTACGCTGATGATCGGCCGCGTGCTCTGGGGCGAGTTCTTCAATAACCG
CGACTGGCCGGTGGCCGCCGCGGTAGCCACGGTGATGCTGGTGCTGCTGCTGGTGCCGATCGTGATCTTCCACCGTTACC
AGCAGCGCGAACTGGAAGGGCGGCTGACATGA

Upstream 100 bases:

>100_bases
ACCAGGGGGGCGCGGCCGGCGCTCGGAATCCTCATGTACCACACGTACACTGCGGTTCCTCCGCGCCGTCCGCGCCCCCC
TGGCGACTGCTCGCTACGTT

Downstream 100 bases:

>100_bases
TGCGCGCCGCGCGCGGTGGGCGTGTGCTGGGCGGCAGCGTGCTCGCGCTGGGGTTCGGTTTTTTGTATCTGCCGATCCTG
TTGCTGATGGTGTATTCGTT

Product: polyamine transport protein

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MLTTLSRGLPGARWGVIAAPYLWLLVFFAIPFLIVLKISFAERATAMPPYTPLFAYAADGAVSLKLHLGNYLALLRDSQY
VAAYLSSIKIAAISTALALLIGYPMAYVIARLPLATRNVAMMLVVLPSWTSFLIRVYAWIGILDGNGLLNQALLALGVIE
QPLQLLYTPIAAYIGFVYCYLPFMVLPLYANLVKHDSRLLEVAYDLGARPWQAFVRITLPLSRNGIVAGCMLVMIPAVGE
FVIPEMLGGPGTLMIGRVLWGEFFNNRDWPVAAAVATVMLVLLLVPIVIFHRYQQRELEGRLT

Sequences:

>Translated_303_residues
MLTTLSRGLPGARWGVIAAPYLWLLVFFAIPFLIVLKISFAERATAMPPYTPLFAYAADGAVSLKLHLGNYLALLRDSQY
VAAYLSSIKIAAISTALALLIGYPMAYVIARLPLATRNVAMMLVVLPSWTSFLIRVYAWIGILDGNGLLNQALLALGVIE
QPLQLLYTPIAAYIGFVYCYLPFMVLPLYANLVKHDSRLLEVAYDLGARPWQAFVRITLPLSRNGIVAGCMLVMIPAVGE
FVIPEMLGGPGTLMIGRVLWGEFFNNRDWPVAAAVATVMLVLLLVPIVIFHRYQQRELEGRLT
>Mature_303_residues
MLTTLSRGLPGARWGVIAAPYLWLLVFFAIPFLIVLKISFAERATAMPPYTPLFAYAADGAVSLKLHLGNYLALLRDSQY
VAAYLSSIKIAAISTALALLIGYPMAYVIARLPLATRNVAMMLVVLPSWTSFLIRVYAWIGILDGNGLLNQALLALGVIE
QPLQLLYTPIAAYIGFVYCYLPFMVLPLYANLVKHDSRLLEVAYDLGARPWQAFVRITLPLSRNGIVAGCMLVMIPAVGE
FVIPEMLGGPGTLMIGRVLWGEFFNNRDWPVAAAVATVMLVLLLVPIVIFHRYQQRELEGRLT

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine [H]

COG id: COG1176

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787080, Length=283, Percent_Identity=61.13074204947, Blast_Score=328, Evalue=2e-91,
Organism=Escherichia coli, GI1787369, Length=282, Percent_Identity=39.3617021276596, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787713, Length=246, Percent_Identity=29.6747967479675, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33444; Mature: 33444

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTLSRGLPGARWGVIAAPYLWLLVFFAIPFLIVLKISFAERATAMPPYTPLFAYAADG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCC
AVSLKLHLGNYLALLRDSQYVAAYLSSIKIAAISTALALLIGYPMAYVIARLPLATRNVA
EEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
MMLVVLPSWTSFLIRVYAWIGILDGNGLLNQALLALGVIEQPLQLLYTPIAAYIGFVYCY
HHEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPFMVLPLYANLVKHDSRLLEVAYDLGARPWQAFVRITLPLSRNGIVAGCMLVMIPAVGE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHEEEEECCCCCCHHHHHHHHHHHHHHH
FVIPEMLGGPGTLMIGRVLWGEFFNNRDWPVAAAVATVMLVLLLVPIVIFHRYQQRELEG
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RLT
CCC
>Mature Secondary Structure
MLTTLSRGLPGARWGVIAAPYLWLLVFFAIPFLIVLKISFAERATAMPPYTPLFAYAADG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCC
AVSLKLHLGNYLALLRDSQYVAAYLSSIKIAAISTALALLIGYPMAYVIARLPLATRNVA
EEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
MMLVVLPSWTSFLIRVYAWIGILDGNGLLNQALLALGVIEQPLQLLYTPIAAYIGFVYCY
HHEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPFMVLPLYANLVKHDSRLLEVAYDLGARPWQAFVRITLPLSRNGIVAGCMLVMIPAVGE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHEEEEECCCCCCHHHHHHHHHHHHHHH
FVIPEMLGGPGTLMIGRVLWGEFFNNRDWPVAAAVATVMLVLLLVPIVIFHRYQQRELEG
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RLT
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8416922; 8905232; 9278503 [H]