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The map label for this gene is pgl [H]

Identifier: 66768296

GI number: 66768296

Start: 2387974

End: 2388693

Strand: Reverse

Name: pgl [H]

Synonym: XC_1975

Alternate gene names: 66768296

Gene position: 2388693-2387974 (Counterclockwise)

Preceding gene: 66768297

Following gene: 66768295

Centisome position: 46.39

GC content: 68.47

Gene sequence:

>720_bases
ATGAGTTTGCAGGACAACGACCGCATCAGCCTGGTGCGCTACGACGACCTCGACGAATGGACCGAAGCGGTGGCCAGCGA
AATGGCCGACCTGCTGGAACAGGAAATCTCGCGCCGCGGCCAGGCGCGCATGCTGCTGTCCGGCGGCACCACCCCGGCGC
CGGTGTACGAATCGCTGGCGCATCGCCCGCTGGATTGGTCGCGGGTCGAGGTGGGCCTGGTGGATGAGCGCTGGCTCTCT
CCACAGGACCAGGACAGCAATGCCTGGCTGGTCAAGCAGAGCTTCCTGGACCATGCACCGGCGGCCACCTTCATTCCGTT
GGTGCGCCCGGGCAAGCAGTTGCCCGAGTGCGTGCATACCGCCAACCTGCAGGCCACGCATGCCGAACCGGCCTGCCTGG
CGGTGATGGGCATGGGCGGCGACGGGCATACCGCCTCGCTATTCCCCGGCTCGACCGATCTACCCAAGGCCCTGGCCAGC
CCGCAGCCGTACGCGTCGCTGGACGCCACCGGCTGCCCCGGTGCCAACCAGTGGCCGCTGCGCATCACCTTGACCCCGGC
CGGGCTGGCGCCAATTCCCACGCGCCTGCTGTTGCTGCGCGGCAAGCAGAAGCTCGATGTGCTGCAGGCGGCGCTGGCAG
GCGAGGACATCAGCGAATACCCGATCCGGGTCGCGCTGCAGCAGCCTGGCCCGCGCCTGCGGGTGCATTGGTGCAGTTAG

Upstream 100 bases:

>100_bases
CGCGGGTGCCCTCGCTGGCGGTGATGCATCCGCATGCCGGCCTCCTGGGTGCAGCGGCGTATGCGGTGGACGCCGAACGC
GCATTGCCGGGAGAGCAGCG

Downstream 100 bases:

>100_bases
TGGATGTCGGGACCTCGGGTGGGTGGCTTGGTCATGCTGATGGCGTGCAAGCACTTGCCCACGTTGTGATACCGCGGCAG
CCCGCATCGCCTGATGCCGG

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSLQDNDRISLVRYDDLDEWTEAVASEMADLLEQEISRRGQARMLLSGGTTPAPVYESLAHRPLDWSRVEVGLVDERWLS
PQDQDSNAWLVKQSFLDHAPAATFIPLVRPGKQLPECVHTANLQATHAEPACLAVMGMGGDGHTASLFPGSTDLPKALAS
PQPYASLDATGCPGANQWPLRITLTPAGLAPIPTRLLLLRGKQKLDVLQAALAGEDISEYPIRVALQQPGPRLRVHWCS

Sequences:

>Translated_239_residues
MSLQDNDRISLVRYDDLDEWTEAVASEMADLLEQEISRRGQARMLLSGGTTPAPVYESLAHRPLDWSRVEVGLVDERWLS
PQDQDSNAWLVKQSFLDHAPAATFIPLVRPGKQLPECVHTANLQATHAEPACLAVMGMGGDGHTASLFPGSTDLPKALAS
PQPYASLDATGCPGANQWPLRITLTPAGLAPIPTRLLLLRGKQKLDVLQAALAGEDISEYPIRVALQQPGPRLRVHWCS
>Mature_238_residues
SLQDNDRISLVRYDDLDEWTEAVASEMADLLEQEISRRGQARMLLSGGTTPAPVYESLAHRPLDWSRVEVGLVDERWLSP
QDQDSNAWLVKQSFLDHAPAATFIPLVRPGKQLPECVHTANLQATHAEPACLAVMGMGGDGHTASLFPGSTDLPKALASP
QPYASLDATGCPGANQWPLRITLTPAGLAPIPTRLLLLRGKQKLDVLQAALAGEDISEYPIRVALQQPGPRLRVHWCS

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 26039; Mature: 25908

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQDNDRISLVRYDDLDEWTEAVASEMADLLEQEISRRGQARMLLSGGTTPAPVYESLA
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
HRPLDWSRVEVGLVDERWLSPQDQDSNAWLVKQSFLDHAPAATFIPLVRPGKQLPECVHT
CCCCCCCEEEEEEEHHHCCCCCCCCCCEEEEEHHHHCCCCCHHEECCCCCCHHHHHHHHH
ANLQATHAEPACLAVMGMGGDGHTASLFPGSTDLPKALASPQPYASLDATGCPGANQWPL
CCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCE
RITLTPAGLAPIPTRLLLLRGKQKLDVLQAALAGEDISEYPIRVALQQPGPRLRVHWCS
EEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECC
>Mature Secondary Structure 
SLQDNDRISLVRYDDLDEWTEAVASEMADLLEQEISRRGQARMLLSGGTTPAPVYESLA
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
HRPLDWSRVEVGLVDERWLSPQDQDSNAWLVKQSFLDHAPAATFIPLVRPGKQLPECVHT
CCCCCCCEEEEEEEHHHCCCCCCCCCCEEEEEHHHHCCCCCHHEECCCCCCHHHHHHHHH
ANLQATHAEPACLAVMGMGGDGHTASLFPGSTDLPKALASPQPYASLDATGCPGANQWPL
CCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCE
RITLTPAGLAPIPTRLLLLRGKQKLDVLQAALAGEDISEYPIRVALQQPGPRLRVHWCS
EEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]