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The map label for this gene is glk [H]

Identifier: 66768297

GI number: 66768297

Start: 2388690

End: 2389697

Strand: Reverse

Name: glk [H]

Synonym: XC_1976

Alternate gene names: 66768297

Gene position: 2389697-2388690 (Counterclockwise)

Preceding gene: 66768298

Following gene: 66768296

Centisome position: 46.41

GC content: 68.35

Gene sequence:

>1008_bases
ATGACTGCTCCTTCCAAGCCGGTGCTGGTTGCCGACATCGGTGGCACCAACGCGCGCTTCGCGCTGGCCGACATCGATGC
CTCGGTACCGCTGCTGGACGACACCTGCCGTGAGTTCGCGGTGGTCGAGTTCGGCTCGCTGGGCGAGGCCGCGCGCTATT
ACCTGGACCAGATTGGCGTGCAGGCCACCAAGGGCGTGTTCGCGGTGGCCGGCCGTGTGGATGGCGACGAAGCCCGCATC
ACCAACCATCCGTGGGTGATCTCGCGCTCGCGCACCGCCACCATGCTGGGCTTCAGCACGCTGCACCTGATCAACGACTT
CGCCGCGCAAGCGATGGCGATCAGCCTGCTGCGCCCGCAGGACGTGGTGCAGGTGGGCGGCGCCAGCTGGCGCCCGGCAC
CGATCGAGCTGCCGCGCAACTACGGCGTCATCGGCCCGGGCACCGGGCTGGGCGTGGGTGGCCTGATCATCCGCAACGGC
CGCTGTTTTCCGCTGGAAACCGAAGGCGGCCATGTCAGCTTCCCGCCCGGCACGCCGGAAGAGATTCGCGTGCTGGAGAT
CCTGTCCGAGCAGTTCGGCCGGGTCTCCAACGAGCGCCTGATCTGCGGCCCGGGCCTGGTCAACATCCACCGCGCGCTGA
GCGAGATTGCCGGCATCGACCCCGGCCCGCTGGAGCCCAAGGACATCACCGCACGTGCCGCCGCTGGCGACCCGCGTGCC
TCGCGCACCATTGATCTGTTCTGCGCCATCTTCGGCGCGATCGCCGGTGACATGGTGCTGATGCAGGGTGCCTGGGACGG
CGTCTTCCTCACCGGCGGGCTGGTGCCCAAGGTGCTGGATTCGCTGCAGCATTCCGGCTTCCGCCAGCGCTTCGAACACA
AGGGCCGTTTCTCCGCAATCATGTCGCGGGTGCCCTCGCTGGCGGTGATGCATCCGCATGCCGGCCTCCTGGGTGCAGCG
GCGTATGCGGTGGACGCCGAACGCGCATTGCCGGGAGAGCAGCGATGA

Upstream 100 bases:

>100_bases
ACGCACAGCTGCCGCTGCAGCCGTATCCGGCCGGTAGCTGGGGCCCCGAGACCGCCGCACCGTTCCTGCCCCCGGCCACC
GACGCACAGGGAAACAACGC

Downstream 100 bases:

>100_bases
GTTTGCAGGACAACGACCGCATCAGCCTGGTGCGCTACGACGACCTCGACGAATGGACCGAAGCGGTGGCCAGCGAAATG
GCCGACCTGCTGGAACAGGA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTAPSKPVLVADIGGTNARFALADIDASVPLLDDTCREFAVVEFGSLGEAARYYLDQIGVQATKGVFAVAGRVDGDEARI
TNHPWVISRSRTATMLGFSTLHLINDFAAQAMAISLLRPQDVVQVGGASWRPAPIELPRNYGVIGPGTGLGVGGLIIRNG
RCFPLETEGGHVSFPPGTPEEIRVLEILSEQFGRVSNERLICGPGLVNIHRALSEIAGIDPGPLEPKDITARAAAGDPRA
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAIMSRVPSLAVMHPHAGLLGAA
AYAVDAERALPGEQR

Sequences:

>Translated_335_residues
MTAPSKPVLVADIGGTNARFALADIDASVPLLDDTCREFAVVEFGSLGEAARYYLDQIGVQATKGVFAVAGRVDGDEARI
TNHPWVISRSRTATMLGFSTLHLINDFAAQAMAISLLRPQDVVQVGGASWRPAPIELPRNYGVIGPGTGLGVGGLIIRNG
RCFPLETEGGHVSFPPGTPEEIRVLEILSEQFGRVSNERLICGPGLVNIHRALSEIAGIDPGPLEPKDITARAAAGDPRA
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAIMSRVPSLAVMHPHAGLLGAA
AYAVDAERALPGEQR
>Mature_334_residues
TAPSKPVLVADIGGTNARFALADIDASVPLLDDTCREFAVVEFGSLGEAARYYLDQIGVQATKGVFAVAGRVDGDEARIT
NHPWVISRSRTATMLGFSTLHLINDFAAQAMAISLLRPQDVVQVGGASWRPAPIELPRNYGVIGPGTGLGVGGLIIRNGR
CFPLETEGGHVSFPPGTPEEIRVLEILSEQFGRVSNERLICGPGLVNIHRALSEIAGIDPGPLEPKDITARAAAGDPRAS
RTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAIMSRVPSLAVMHPHAGLLGAAA
YAVDAERALPGEQR

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=319, Percent_Identity=41.692789968652, Blast_Score=232, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 35520; Mature: 35389

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSKPVLVADIGGTNARFALADIDASVPLLDDTCREFAVVEFGSLGEAARYYLDQIGV
CCCCCCCEEEEECCCCCCEEEEEECCCCCCCHHHHHHHEEEEECCCCCHHHHHHHHHHCC
QATKGVFAVAGRVDGDEARITNHPWVISRSRTATMLGFSTLHLINDFAAQAMAISLLRPQ
HHHCCEEEEEECCCCCCCEECCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCH
DVVQVGGASWRPAPIELPRNYGVIGPGTGLGVGGLIIRNGRCFPLETEGGHVSFPPGTPE
HHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCEEEEEECCCCEEECCCCCHH
EIRVLEILSEQFGRVSNERLICGPGLVNIHRALSEIAGIDPGPLEPKDITARAAAGDPRA
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCC
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAI
HHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHH
MSRVPSLAVMHPHAGLLGAAAYAVDAERALPGEQR
HHHCCCEEEECCCCCHHHHHHHHCCHHHCCCCCCC
>Mature Secondary Structure 
TAPSKPVLVADIGGTNARFALADIDASVPLLDDTCREFAVVEFGSLGEAARYYLDQIGV
CCCCCCEEEEECCCCCCEEEEEECCCCCCCHHHHHHHEEEEECCCCCHHHHHHHHHHCC
QATKGVFAVAGRVDGDEARITNHPWVISRSRTATMLGFSTLHLINDFAAQAMAISLLRPQ
HHHCCEEEEEECCCCCCCEECCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCH
DVVQVGGASWRPAPIELPRNYGVIGPGTGLGVGGLIIRNGRCFPLETEGGHVSFPPGTPE
HHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCEEEEEECCCCEEECCCCCHH
EIRVLEILSEQFGRVSNERLICGPGLVNIHRALSEIAGIDPGPLEPKDITARAAAGDPRA
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCC
SRTIDLFCAIFGAIAGDMVLMQGAWDGVFLTGGLVPKVLDSLQHSGFRQRFEHKGRFSAI
HHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHH
MSRVPSLAVMHPHAGLLGAAAYAVDAERALPGEQR
HHHCCCEEEECCCCCHHHHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]