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The map label for this gene is argC

Identifier: 66768196

GI number: 66768196

Start: 2269203

End: 2270153

Strand: Direct

Name: argC

Synonym: XC_1875

Alternate gene names: 66768196

Gene position: 2269203-2270153 (Clockwise)

Preceding gene: 66768195

Following gene: 66768197

Centisome position: 44.07

GC content: 66.04

Gene sequence:

>951_bases
ATGACTGTTCAACCAACCACCATCGGCATTGTGGGCGCACGCGGCCATACCGGCGCGGAGCTGATCAAGCTGATTGCCGC
GCACCCGCAGTTGCAGCTGGTGTTCGTGTCCTCGCGCGAGCTCGCCGGCCAGCGCGTGGCCGAGCACAGCGATGGCTATG
AGGGCGAGCTGCGCTATGAAAGCCTGGACGCCGACGCGGTGGCTGCCAAGGCCGCGGACGTGGTGATCCTGGCATTGCCC
AACGGCAAGGCCGAGCCCTTCGTGGCGGCCATCGATGCCAACCGGCCGCAGACGTTGCTGATCGACCTGTCGGCCGACTA
CCGCTTCGATCCGGCCTGGTATTACGGCTTGCCGGAGCTTACCCGCCACACCTACGCCGGGCAGCGCCGCATCAGCAATC
CCGGCTGCTATGCCACGGCCATGCAGCTGGCGATCACGCCGCTGCGCGAGCAACTGGCAGGGCCGCCGCAGTGCTTTGGC
GTCTCCGGCTATTCCGGTGCGGGCACCACGCCTTCAGACAAGAACAATCCCGCGTTGCTGGCCGACAACCTGATGCCGTA
CGCGCTGACCAACCACATGCACGAGCGCGAAGTCTCCGCGCAGCTCGGCGTGCCGGTGGAATTCATGCCGCATGTGGCGC
CGCATTTCCGCGGCATCACCATGACCGTGAACCTGTGGCTGCAGCAGCCGTTGACGCGCGAGCAGATCCACGCACGCTAC
CTGGAGCGGTATGCGCATGAGCCCTTGATCGAGATCGTGGACGAGGCGCCGTGGGTGAGCCGTATCGCCGGCACCCAGGG
CGTGCAGATCGGTGGGTTCACCATGGCGCCGGGCAACAAGCGCGTGGTGGTGGTGGCAACGCTGGACAACCTGCTCAAGG
GTGCGGCCACGCAGGCCATGCAGAACCTCAACCTGGCGCTGGGCTGGGACGAATTGACCGCAATTGGCTGA

Upstream 100 bases:

>100_bases
ACGCCGACGGCACGCCACGCGACACCGTGGTGTTTTCCATCATCAATGCGGAATGGGCCGGGGTGAAACGCCACCTGCAG
TTCCGCCTGGACGCACACGC

Downstream 100 bases:

>100_bases
TGCGCGTCCCTCGCAAGCGCCCGCACATCCATCTGCGGGGATTCAATTGGACGACTTATTTCGAGACGCTTTCCGATGAC
CAATCTGTTGTGGCAAAAAC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTVQPTTIGIVGARGHTGAELIKLIAAHPQLQLVFVSSRELAGQRVAEHSDGYEGELRYESLDADAVAAKAADVVILALP
NGKAEPFVAAIDANRPQTLLIDLSADYRFDPAWYYGLPELTRHTYAGQRRISNPGCYATAMQLAITPLREQLAGPPQCFG
VSGYSGAGTTPSDKNNPALLADNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIHARY
LERYAHEPLIEIVDEAPWVSRIAGTQGVQIGGFTMAPGNKRVVVVATLDNLLKGAATQAMQNLNLALGWDELTAIG

Sequences:

>Translated_316_residues
MTVQPTTIGIVGARGHTGAELIKLIAAHPQLQLVFVSSRELAGQRVAEHSDGYEGELRYESLDADAVAAKAADVVILALP
NGKAEPFVAAIDANRPQTLLIDLSADYRFDPAWYYGLPELTRHTYAGQRRISNPGCYATAMQLAITPLREQLAGPPQCFG
VSGYSGAGTTPSDKNNPALLADNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIHARY
LERYAHEPLIEIVDEAPWVSRIAGTQGVQIGGFTMAPGNKRVVVVATLDNLLKGAATQAMQNLNLALGWDELTAIG
>Mature_315_residues
TVQPTTIGIVGARGHTGAELIKLIAAHPQLQLVFVSSRELAGQRVAEHSDGYEGELRYESLDADAVAAKAADVVILALPN
GKAEPFVAAIDANRPQTLLIDLSADYRFDPAWYYGLPELTRHTYAGQRRISNPGCYATAMQLAITPLREQLAGPPQCFGV
SGYSGAGTTPSDKNNPALLADNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIHARYL
ERYAHEPLIEIVDEAPWVSRIAGTQGVQIGGFTMAPGNKRVVVVATLDNLLKGAATQAMQNLNLALGWDELTAIG

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=339, Percent_Identity=29.7935103244838, Blast_Score=121, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6320913, Length=323, Percent_Identity=47.3684210526316, Blast_Score=295, Evalue=7e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_XANC8 (Q4UVI5)

Other databases:

- EMBL:   CP000050
- RefSeq:   YP_242958.1
- HSSP:   Q9X2A2
- ProteinModelPortal:   Q4UVI5
- SMR:   Q4UVI5
- STRING:   Q4UVI5
- GeneID:   3380422
- GenomeReviews:   CP000050_GR
- KEGG:   xcb:XC_1875
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   XCAM314565:XC_1875-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh

EC number: =1.2.1.38

Molecular weight: Translated: 34264; Mature: 34132

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 136-136

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQPTTIGIVGARGHTGAELIKLIAAHPQLQLVFVSSRELAGQRVAEHSDGYEGELRYE
CCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCCCEEEEE
SLDADAVAAKAADVVILALPNGKAEPFVAAIDANRPQTLLIDLSADYRFDPAWYYGLPEL
CCCCHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCEECCCEECCCHHH
TRHTYAGQRRISNPGCYATAMQLAITPLREQLAGPPQCFGVSGYSGAGTTPSDKNNPALL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEE
ADNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIHARY
ECCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHCCEEEEEEEEECCCCCHHHHHHHH
LERYAHEPLIEIVDEAPWVSRIAGTQGVQIGGFTMAPGNKRVVVVATLDNLLKGAATQAM
HHHHHCCHHHHHHHCCCHHHHHCCCCCEEECCEEECCCCCEEEEEEEHHHHHHHHHHHHH
QNLNLALGWDELTAIG
HHCCEEECCHHHHCCC
>Mature Secondary Structure 
TVQPTTIGIVGARGHTGAELIKLIAAHPQLQLVFVSSRELAGQRVAEHSDGYEGELRYE
CCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCCCEEEEE
SLDADAVAAKAADVVILALPNGKAEPFVAAIDANRPQTLLIDLSADYRFDPAWYYGLPEL
CCCCHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCEECCCEECCCHHH
TRHTYAGQRRISNPGCYATAMQLAITPLREQLAGPPQCFGVSGYSGAGTTPSDKNNPALL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEE
ADNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIHARY
ECCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHCCEEEEEEEEECCCCCHHHHHHHH
LERYAHEPLIEIVDEAPWVSRIAGTQGVQIGGFTMAPGNKRVVVVATLDNLLKGAATQAM
HHHHHCCHHHHHHHCCCHHHHHCCCCCEEECCEEECCCCCEEEEEEEHHHHHHHHHHHHH
QNLNLALGWDELTAIG
HHCCEEECCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA